31 julio 2012

STROKE. Retrospective Multicenter Study of Solitaire FR for Revascularization in the Treatment of Acute Ischemic Stroke

Antoni Dávalos, MD; Vitor Mendes Pereira, MD; René Chapot, MD; Alain Bonafé, MD; Tommy Andersson, MD; Jan Gralla, MD by the Solitaire Group

Background and Purpose—The purpose of this study was to evaluate safety and efficacy of the Solitaire FR device in the treatment of patients with acute ischemic stroke secondary to large artery occlusion. Stroke. 2012; 43: 2699-2705 Published online before print July 31, 2012, doi: 10.1161/​STROKEAHA.112.663328. Copyright © 2012 American Heart Association, Inc. All rights reserved.

21 agosto 2012

STROKE. Predictors of Recurrent Stroke in Patients With Symptomatic Intracranial Arterial Stenosis

Jin-Man Jung, MD; Dong-Wha Kang, MD; Kyung-Ho Yu, MD; Ja-seong Koo, MD; Ju-Hun Lee, MD; Jong-Moo Park, MD; Keun-Sik Hong, MD; Yong-Jin Cho, MD; Jong S. Kim, MD; Sun U. Kwon, MD on behalf of the TOSS-2 Investigators

Background and Purpose—Our goal was to investigate whether initial ischemic lesion pattern can predict stroke recurrence in patients with symptomatic intracranial arterial stenosis. 2012; 43: 2785-2787 Published online before print August 21, 2012, doi: 10.1161/​STROKEAHA.112.659185. Copyright © 2012 American Heart Association, Inc. All rights reserved.

01 octubre 2012

AMERICAN JOURNAL OF NEURORADIOLOGY. Effects of Flow-Diverting Device Oversizing on Hemodynamics Alteration in Cerebral Aneurysms

F. Mut and J.R. Cebral

BACKGROUND AND PURPOSE: Flow-diverting devices are increasingly being considered for large or giant aneurysms with wide necks, which are difficult to treat with coils or clips. These devices are often oversized to achieve good positioning against the artery wall. The objective of this study was to analyze the effect of oversized flow-diverting devices in altering aneurysmal flows and creating hemodynamic environments favorable for thrombosis and aneurysm occlusion. Published online before print May 3, 2012, doi: 10.3174/ajnr.A3080 AJNR 2012 33: 2010-2016 . Copyright © 2012 by American Journal of Neuroradiology

01 noviembre 2012

STROKE. Secondary Intracerebral Hemorrhage Due to Early Initiation of Oral Anticoagulation After Ischemic Stroke. An Experimental Study in Mice

Michael Gliem, MD; Derik Hermsen, MD; Nico van Rooijen, PhD; Hans-Peter Hartung, MD; Sebastian Jander, MD

Background and Purpose—The uncertain risk of secondary intracerebral hemorrhage (sICH) frequently keeps clinicians from initiating oral anticoagulation (OAC) early after ischemic cardioembolic stroke. The goal of this experimental study was to determine the risk of sICH depending on the timing of OAC initiation relative to stroke onset and to address the role of hematogenous macrophages for repair processes preventing OAC-associated sICH. Stroke. 2012; 43: 3352-3357 Published online before print November 1, 2012, doi: 10.1161/​STROKEAHA.112.666818. Copyright © 2012 American Heart Association, Inc. All rights reserved.

01 noviembre 2012

STROKE. Randomized Controlled Trial of Symptomatic Middle Cerebral Artery Stenosis. Endovascular Versus Medical Therapy in a Chinese population

Zhongrong Miao, MD, PhD; Lidan Jiang, MD; Hao Wu, MD, PhD; Yuhai Bao, MD, PhD; Liqun Jiao, MD, PhD; Shenmao Li, MD; Jian Wu, MD, PhD; Yang Hua, MD, PhD; Yan Li, MD; Junlei Zhu, MD; Fengshui Zhu, MD; Xuezong Liu, MD; Feng Ling, MD, PhD

Background and Purpose—To investigate the efficacy and safety of percutaneous transluminal angioplasty and stenting (PTAS) for symptomatic middle cerebral artery stenosis compared with standard medical treatment in a low-risk Chinese population. Stroke. 2012; 43: 3284-3290 Published online before print November 1, 2012, doi: 10.1161/​STROKEAHA.112.662270. Copyright © 2012 American Heart Association, Inc. All rights reserved.

01 noviembre 2012

STROKE. Cerebrovascular Reserve and Stroke Risk in Patients With Carotid Stenosis or Occlusion. A Systematic Review and Meta-Analysis

Ajay Gupta, MD; J. Levi Chazen, MD; Maya Hartman, MD, MBA; Diana Delgado, MLS; Nikesh Anumula, MD; Huibo Shao, MS; Madhu Mazumdar, PhD; Alan Z. Segal, MD; Hooman Kamel, MD; Dana Leifer, MD; Pina C. Sanelli, MD, MPH

Background and Purpose—Impairments in cerebrovascular reserve (CVR) have been variably associated with increased risk of ischemic events and may stratify stroke risk in patients with high-grade internal carotid artery stenosis or occlusion. The purpose of this study is to perform a systematic review and meta-analysis to summarize the association of CVR impairment and stroke risk. Stroke. 2012; 43: 2884-2891 doi: 10.1161/​STROKEAHA.112.663716. Copyright © 2012 American Heart Association, Inc. All rights reserved.

01 noviembre 2012

STROKE. Antithrombotic Therapy and Bleeding Risk in a Prospective Cohort Study of Patients With Cerebral Cavernous Malformations

Hans-Martin Schneble, MD; Aicha Soumare, PhD; Dominique Hervé, MD, PhD; Damien Bresson, MD; Jean-Pierre Guichard, MD; Florence Riant, MD, PhD; Elisabeth Tournier-Lasserve, MD, PhD; Christophe Tzourio, MD, PhD; Hugues Chabriat, MD, PhD; Christian Stapf, MD

Background and Purpose—Cerebral cavernous malformations (CCMs) are one of the most frequently diagnosed vascular malformations of the brain and constitute a potential source of intracranial hemorrhage. In CCM patients suffering ischemic stroke or heart disease, the use of anticoagulants or antiplatelet therapy is generally avoided by fear of hemorrhagic complications, but no systematic studies exist to support this hypothesis. 2012; 43: 3196-3199 Published online before print November 13, 2012, doi: 10.1161/​STROKEAHA.112.668533. Copyright © 2012 American Heart Association, Inc. All rights reserved.

01 noviembre 2012

STROKE. Risk Prediction for Adverse Events After Carotid Artery Stenting in Higher Surgical Risk Patients

Neil J. Wimmer, MD; Robert W. Yeh, MD, MSc; Donald E. Cutlip, MD; Laura Mauri, MD, MSc

Background and Purpose—The goal of carotid artery stenting is to decrease the risk of stroke or other adverse events from carotid artery disease. Choosing a treatment strategy requires patient-specific information regarding periprocedural risk of adverse neurologic events. The aim of this study was to predict individual patient risk after carotid artery stenting in patients at higher risk for carotid endarterectomy. Stroke. 2012; 43: 3218-3224 Published online before print November 5, 2012, doi: 10.1161/​STROKEAHA.112.673194. Copyright © 2012 American Heart Association, Inc. All rights reserved.

01 noviembre 2012

STROKE. Stent-Based Thrombectomy Versus Intravenous Tissue Plasminogen Activator in Patients With Acute Middle Cerebral Artery Occlusion

Ronen R. Leker, MD FAHA; Roni Eichel, MD; John M. Gomori, MD; Fernando Ramirez de Noriega, MD; Tamir Ben-Hur, MD, PhD; Jose E. Cohen, MD

Background and Purpose—Our goal was to compare outcomes of patients with proximal middle cerebral artery occlusions treated with intravenous tissue plasminogen activator (tPA) with those of patients treated with stent-based thrombectomy (SBT). Stroke. 2012; 43: 3389-3391 Published online before print October 2, 2012, doi: 10.1161/​STROKEAHA.112.673665. Copyright © 2012 American Heart Association, Inc. All rights reserved.

01 noviembre 2012

JVIR. Stent Placement for Treatment of Long Segment (≥80mm) Carotid Artery Stenosis in Patients with Takayasu Disease

Jun Hu, MD, PhD , Heqing Huang, MD , Xiaofei Zhang, MD, MS , Guangjian Li, MD , Qu Liu, MD , Min Wu, MD , Gui Li, MD, PhD , Kangning Chen, MD, PhDemail address , Shugui Shi, MD, PhD

Purpose: To evaluate the effectiveness and safety of carotid artery stent (CAS) placement for treatment of long segment stenosis in patients with Takayasu arteritis. Journal of Vascular and Interventional Radiology Volume 23, Issue 11 , Pages 1473-1477, November 2012. November 2011. Copyright © 2012 SIR. Published by Elsevier Inc. All rights reserved.

15 noviembre 2012

STROKE. Final Infarct Volume Is a Stronger Predictor of Outcome Than Recanalization in Patients With Proximal Middle Cerebral Artery Occlusion Treated With Endovascular Therapy

Syed F. Zaidi, MD, Amin Aghaebrahim, MD, Xabier Urra, MD, Mouhammad A. Jumaa, MD, Brian Jankowitz, MD, Maxim Hammer, MD, Raul Nogueira, MD, Michael Horowitz, MD, Vivek Reddy, MD and Tudor G. Jovin, MD

Background and Purpose—The rationale for recanalization therapy in acute ischemic stroke is to preserve brain through penumbral salvage and thus improve clinical outcomes. We sought to determine the relationship between recanalization, clinical outcomes, and final infarct volumes in acute ischemic stroke patients presenting with middle cerebral artery occlusion who underwent endovascular therapy and post-procedure magnetic resonance imaging. STROKEAHA.112.671594 Published online before print November 15, 2012, doi: 10.1161/​STROKEAHA.112.671594. Copyright © 2012 American Heart Association, Inc.

01 noviembre 2012

STROKE. Persistent Hemodynamic Changes in Ruptured Brain Arteriovenous Malformations

Till Illies, MD; Nils Daniel Forkert, MSc; Dennis Saering, PhD; Karolin Wenzel; Thorsten Ries, MD; Jan Regelsberger, MD; Karl Wegscheider, PhD; Jens Fiehler, MD

Background and Purpose—Hemodynamic properties of brain arteriovenous malformations (AVMs) with risk factors for a future hemorrhage are essentially unknown. We hypothesized that AVMs with anatomic properties, which are associated with an increased rupture risk, exhibit different hemodynamic characteristics than those without these properties. Stroke. 2012; 43: 2910-2915 doi: 10.1161/​STROKEAHA.112.669945. Copyright © 2012 American Heart Association, Inc. All rights reserved.

13 septiembre 2012

STROKE. Associations Among Vascular Risk Factors, Carotid Atherosclerosis, and Cortical Volume and Thickness in Older Adults

Valerie A. Cardenas, PhD; Bruce Reed, PhD; Linda L. Chao, PhD; Helena Chui, MD; Nerses Sanossian, MD; Charles C. DeCarli, MD; Wendy Mack, PhD; Joel Kramer, PsyD; Howard N. Hodis, MD; Mingzhu Yan, MD, PhD; Michael H. Buonocore, MD, PhD; Owen Carmichael, PhD; William J. Jagust, MD; Michael W. Weiner, MD

Background and Purpose—The purpose of this study was to investigate whether the Framingham Cardiovascular Risk Profile and carotid artery intima-media thickness are associated with cortical volume and thickness. Stroke. 2012; 43: 2865-2870 Published online before print September 13, 2012, doi: 10.1161/​STROKEAHA.112.659722. Copyright © 2012 American Heart Association, Inc. All rights reserved.

03 octubre 2012

NEUROSURGERY. Microcatheter Looping Technique for Coil Embolization of Complex Configuration Middle Cerebral Artery Aneurysms

Cho, Young Dae MD; Kang, Hyun-Seung MD. PhD; Kim, Jeong Eun MD. PhD; Son, Young Je MD. PhD; Lee, Jong Young MD; Lee, Seung Jin MD; Seo, Jung Hwa MD; Han, Moon Hee MD, PhD.

Background: Protection techniques using stents or microcatheters allow treatment of aneurysms with complex configurations by coil embolization. However, the application of these techniques is occasionally limited in wide neck middle cerebral artery (MCA) aneurysms with acute angularity of the efferent branch vessel. Neurosurgery: POST ACCEPTANCE, 3 October 2012 doi: 10.1227/NEU.0b013e318271ee1a. Copyright © by the Congress of Neurological Surgeons

04 septiembre 2012

STROKE. Transcranial Doppler Ultrasound for Screening Cerebral Small Vessel Disease

Vincent Mok, MD; Ding Ding, MD, MPH; Jianhui Fu, MD, PhD; Yunyun Xiong, MD, PhD; Winnie W.C. Chu, MD; Defeng Wang, PhD; Jill M. Abrigo, MD; Jie Yang, MD; Adrian Wong, PhD; Qianhua Zhao, MD; Qihao Guo, MD; Zhen Hong, MD; Ka Sing Wong, MD

Background and Purpose: We explored the association between pulsatility index (PI) as derived from transcranial Doppler ultrasound with various measures of small vessel disease in the community. Stroke. 2012; 43: 2791-2793 Published online before print September 4, 2012, doi: 10.1161/​STROKEAHA.112.665711. Copyright © 2012 American Heart Association, Inc.