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ABSTRACT


01 abril 2013

CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY. Mechanical Revascularization for Acute Ischemic Stroke: A Single-Center, Retrospective Analysis

Miran Jeromel, Z. V. Milosevic, I. J. Kocijancic, D. Lovric, V. Svigelj, B. Zvan

Background: Endovascular mechanical revascularization (thrombectomy) is an increasingly used method for intracranial large vessel recanalization in acute stroke. The purpose of the study was to analyze the recanalization rate, clinical outcome, and complication rate in our stroke patients treated with mechanical revascularization.

01 abril 2013

CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY. Elastoplasty: First Experience in 12 Patients

Thijs A. J. Urlings, Edwin van der Linden

Purpose: Percutaneous vertebroplasty with polymethylmethacrylate (PMMA) is used increasingly for pain relief in symptomatic neoplastic or osteoporotic compression fractures. However, restoration of the stiffness of the treated vertebrae might propagate secondary fracture of adjacent vertebrae. Elastoplasty might prevent these secondary fractures. We assessed retrospectively our experience with elastoplasty in 12 patients, focusing on silicone migration.

06 marzo 2013

CIRCULATION. Genetic Determinants of Dabigatran Plasma Levels and Their Relation to Bleeding

Guillaume Paré, MD; Niclas Eriksson, PhD; Thorsten Lehr, PhD; Stuart Connolly, MD; John Eikelboom, MD; Michael D. Ezekowitz, MD, PhD; Tomas Axelsson, PhD; Sebastian Haertter, PhD; Jonas Oldgren, MD, PhD; Paul Reilly, PhD; Agneta Siegbahn, MD, PhD; Ann-Christine Syvanen, PhD; Claes Wadelius, MD, PhD; Mia Wadelius, MD, PhD; Heike Zimdahl-Gelling, PhD; Salim Yusuf, MD; Lars Wallentin, MD, PhD

Background—Fixed-dose unmonitored treatment with dabigatran etexilate is effective and has a favorable safety profile in the prevention of stroke in atrial fibrillation patients compared with warfarin. We hypothesized that genetic variants could contribute to interindividual variability in blood concentrations of the active metabolite of dabigatran etexilate and influence the safety and efficacy of dabigatran.

01 julio 2012

NEURORADIOLOGY. Treatment of intracranial aneurysms. Reconstruction of the parent artery with flow-diverting (Silk) stent

Aase Wagner, Marie Cortsen, John Hauerberg, Bertil Romner, Mathias Pedersen Wagner

Introduction: Since the flow diverters (FDs) have been introduced it is possible to treat aneurysms that are considered difficult or impossible to treat with usual endovascular or surgical methods. It is still uncertain which aneurysms are suitable for this new treatment. We present the periprocedural complications, immediate result, late complications, imaging follow-up at 6 and 12 months and clinical follow-up at 2–23 months.

01 marzo 2013

JOURNAL OF NEURORADIOLOGY. Carotid artery stenting in patients with symptomatic carotid stenosis: A single-center series

I. Kessler, B. Gory, F. Macian, G. Nakiri, M. Al-Khawaldeh, R. Riva, M.P. Boncoeur, C. Mounayer

Objectives: Carotid angioplasty with stenting (CAS) in patients with carotid stenosis (CS) has become more restricted in France especially since the disclosure of such studies as EVA-3S and Stent-supported percutaneous angioplasty of the carotid artery versus endarterectomy (SPACE). This report is of a series of CS cases contraindicated for endarterectomy that underwent CAS at a French center of interventional neuroradiology.

01 marzo 2013

JOURNAL OF VASCULAR SURGERY. Effect of hospital-level variation in the use of carotid artery stenting versus carotid endarterectomy on perioperative stroke and death in asymptomatic patients

Theodore H. Yuo, MD , Howard S. Degenholtz, PhD , Rabih A. Chaer, MD , Kevin L. Kraemer, MD, MSc , Michel S. Makaroun, MD

Objective: Perioperative stroke and death (PSD) are more common after carotid artery stenting (CAS) than after carotid endarterectomy (CEA) in symptomatic patients, but whether this is also true in asymptomatic patients is unclear. Furthermore, use of both CEA and CAS varies geographically, suggesting possible variation in outcomes. We compared odds of PSD after CAS and CEA in asymptomatic patients to determine the impact of this variation.

15 enero 2013

STROKE. Endovascular Treatment of Intracranial Aneurysms With Flow Diverters

Waleed Brinjikji, MD, Mohammad H. Murad, MD, MPH, Giuseppe Lanzino, MD, Harry J. Cloft, MD, PhD and David F. Kallmes, MD

Background and Purpose—Flow diverters are important tools in the treatment of intracranial aneurysms. However, their impact on aneurysmal occlusion rates, morbidity, mortality, and complication rates is not fully examined.

01 marzo 2013

JOURNAL OF VASCULAR SURGERY. The risk of carotid artery stenting compared with carotid endarterectomy is greatest in patients treated within 7 days of symptoms

Barbara Rantner, MD, PhD , Georg Goebel, PhD , Leo H. Bonati, MD , Peter A. Ringleb, MD , Jean-Louis Mas, MD , Gustav Fraedrich, MD , Carotid Stenting Trialists Collaboration

Objective: Among patients with symptomatic carotid artery stenosis, carotid artery stenting (CAS) is associated with a higher risk of periprocedural stroke or death than carotid endarterectomy (CEA). Uncertainty remains whether the balance of risk changes with time since the most recent ischemic event.

01 octubre 2012

ACTA NEUROCHIRURGICA. Flow diversion treatment: intra-aneurismal blood flow velocity and WSS reduction are parameters to predict aneurysm thrombosis

Zsolt Kulcsár, Luca Augsburger, Philippe Reymond, Vitor M. Pereira, Sven Hirsch, Ajit S. Mallik, John Millar, Stephan G. Wetzel, Isabel Wanke, Daniel A. Rüfenacht

Background: To evaluate the haemodynamic changes induced by flow diversion treatment in cerebral aneurysms, resulting in thrombosis or persisting aneurysm patency over time.

01 enero 2012

NEURORADIOLOGY. Initial experiences with the Amplatzer Vascular Plug 4 for permanent occlusion of the internal carotid artery in the skull base in patients with head and neck tumors

Stephan Macht, Christian Mathys, Jörg Schipper, Bernd Turowski

Introduction: As the first report in the literature, we present our initial experiences with the latest generation s Amplatzer Vascular Plug 4 (AVP4) as a device for permanent occlusion of the internal carotid artery in its course in the skull base.

02 agosto 2012

AMERICAN JOURNAL OF NEURORADIOLOGY. Prospective Comparison of Angio-Seal versus Manual Compression for Hemostasis after Neurointerventional Procedures under Systemic Heparinization

H.-F. Wong, C.-W. Lee, Y.-L. Chen, Y.-M. Wu, H.-H. Weng, Y.-H. Wang and H.-M. Liu

BACKGROUND AND PURPOSE: The use of arterial closure device in patients with prolonged high ACT values has not been extensively studied. The aim of this study was to compare the safety and efficacy of an arterial closure device, Angio-Seal, with manual compression in patients on anticoagulation following neurointerventional procedures.

19 julio 2012

AMERICAN JOURNAL OF NEURORADIOLOGY. Mechanical Thrombectomy in Acute Stroke: Prospective Pilot Trial of the Solitaire FR Device while Under Conscious Sedation

S. Soize, K. Kadziolka, L. Estrade, I. Serre, S. Bakchine and L. Pierot

BACKGROUND AND PURPOSE: The best approach between general anesthesia and conscious sedation to perform mechanical thrombectomy remains unknown. The goal of our study was to evaluate the feasibility, safety, and efficacy of mechanical thrombectomy under conscious sedation in patients with acute ischemic stroke, using the Solitaire FR device, in a prospective, single-center, single-arm study.

12 julio 2012

AMERICAN JOURNAL OF NEURORADIOLOGY. Comparison of Stent-Retriever Devices versus the Merci Retriever for Endovascular Treatment of Acute Stroke

E. Broussalis, E. Trinka, W. Hitzl, A. Wallner, V. Chrousa and M. Killer-Oberpfalzer

BACKGROUND AND PURPOSE: Revascularization of large cerebral artery occlusion is the therapeutic goal in stroke therapy. Currently, many recanalization devices are in clinical use. This study compares the outcome parameters, efficacy, and safety of the new generation of stent-retriever devices with the well-established Merci retriever.

02 agosto 2012

AMERICAN JOURNAL OF NEURORADIOLOGY. Canadian Experience with the Pipeline Embolization Device for Repair of Unruptured Intracranial Aneurysms

BACKGROUND AND PURPOSE: Flow-diverting stents, such as the PED, have emerged as a novel means of treating complex intracranial aneurysms. This retrospective analysis of the initial Canadian experience provides insight into technical challenges, clinical and radiographic outcomes, and complication rates after the use of flow-diverting stents for unruptured aneurysms.

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