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ABSTRACT


02 agosto 2016

STROKE. Aspiration Thrombectomy After Intravenous Alteplase Versus Intravenous Alteplase Alone

J Mocco, Osama O. Zaidat, Rüdiger von Kummer, Albert J. Yoo, Rishi Gupta, Demetrius Lopes, Don Frei, Harish Shownkeen, Ron Budzik, Zahra A. Ajani, Aaron Grossman, Dorethea Altschul, Cameron McDougall, Lindsey Blake, Brian-Fred Fitzsimmons, Dileep Yavagal, John Terry, Jeffrey Farkas, Seon Kyu Lee, Blaise Baxter, Martin Wiesmann, Michael Knauth, Donald Heck, Syed Hussain, David Chiu, Michael J. Alexander, Timothy Malisch, Jawad Kirmani, Laszlo Miskolczi and Pooja Khatri and for the THERAPY Trial Investigators*

Background and Purpose: Thrombectomy, primarily with stent retrievers with or without adjunctive aspiration, provided clinical benefit across multiple prospective randomized trials. Whether this benefit is exclusive to stent retrievers is unclear.

09 agosto 2016

STROKE. Prescription of Guideline-Based Medical Therapies at Discharge After Carotid Artery Stenting and Endarterectomy. An NCDR Analysis

Herbert D. Aronow, Kevin F. Kennedy, Siddharth A. Wayangankar, Barry T. Katzen, Peter A. Schneider, Alex Abou-Chebl and Kenneth A. Rosenfield

Background and Purpose: Carotid artery revascularization was previously found to incrementally reduce stroke risk among patients with carotid stenosis treated with medical therapy. However, the frequency with which optimal medical therapies are used at discharge after carotid endarterectomy (CEA) and carotid artery stenting (CAS) is not known, and the influence of patient, operator, and hospital characteristics on the likelihood of prescription is poorly understood.

04 agosto 2016

STROKE. Use and Outcomes of Intravenous Thrombolysis for Acute Ischemic Stroke in Patients ≥90 Years of Age

Rohan Arora, Elliott Salamon, Jeffrey M. Katz, Margueritte Cox, Jeffrey L. Saver, Deepak L. Bhatt, Gregg C. Fonarow, Eric D. Peterson, Eric E. Smith, Lee H. Schwamm, Ying Xian and Richard B. Libman

Background and Purpose: Intravenous tissue-type plasminogen activator (tPA) is a proven treatment for acute ischemic stroke, but there has been limited evaluation among patients aged ≥90 years.

21 julio 2016

STROKE. Stenting as a Rescue Treatment After Failure of Mechanical Thrombectomy for Anterior Circulation Large Artery Occlusion

Jang-Hyun Baek, Byung Moon Kim, Dong Joon Kim, Ji Hoe Heo, Hyo Suk Nam and Joonsang Yoo

Background and Purpose: We hypothesized that permanent stenting may be a rescue treatment for stentriever-failed anterior circulation large artery occlusion. We compared the outcomes among patients with permanent stenting and those without stenting after stentriever failure.

04 agosto 2016

STROKE. Leukoaraiosis, Cerebral Hemorrhage, and Outcome After Intravenous Thrombolysis for Acute Ischemic Stroke. A Meta-Analysis

Andreas Charidimou, Marco Pasi, Marco Fiorelli, Sara Shams, Rüdiger von Kummer, Leonardo Pantoni and Natalia Rost

Background and Purpose: We performed a meta-analysis to assess whether leukoaraiosis on brain computed tomographic scans of acute ischemic stroke patients treated with intravenous thrombolysis is associated with an increased risk of symptomatic intracerebral hemorrhage (sICH) or poor functional outcome at 3 to 6 months after stroke, or both.

07 julio 2016

STROKE. Outcomes With Edoxaban Versus Warfarin in Patients With Previous Cerebrovascular Events. Findings From ENGAGE AF-TIMI 48 (Effective Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction 48)

Natalia S. Rost, Robert P. Giugliano, Christian T. Ruff, Sabina A. Murphy, Andrea E. Crompton, Andrew D. Norden, Scott Silverman, Aneesh B. Singhal, José C. Nicolau, Bhupathi SomaRaju, Michele F. Mercuri, Elliott M. Antman and Eugene Braunwald and on behalf of the ENGAGE AF-TIMI 48 Investigators

Background and Purpose: Patients with atrial fibrillation and previous ischemic stroke (IS)/transient ischemic attack (TIA) are at high risk of recurrent cerebrovascular events despite anticoagulation. In this prespecified subgroup analysis, we compared warfarin with edoxaban in patients with versus without previous IS/TIA.

08 agosto 2016

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Peripheral Vascular Disease. Long-Term Outcomes of Carotid Artery Stenting in Clinical Practice

Harald Mudra, MD, Stephan Staubach, MD, Ralph Hein-Rothweiler, MD, Manuela Segerer, MD, Henning Strohm, MD, Hannes Weber, MD and Jakob Ledwoch, MD

Background: There is a lack of long-term data and data outside of controlled clinical trials in carotid artery stenting. Thus, we sought to evaluate the long-term effectiveness in stroke prevention by carotid artery stenting in a large number of patients in a real-world setting.

01 septiembre 2016

RSNA: Radiology. MR Imaging Measures of Intracranial Atherosclerosis in a Population-based Study

Ye Qiao, PhD, Eliseo Guallar, MD, DrPH, Fareed K. Suri, MD, Li Liu, MS, Yiyi Zhang, PhD, Zeeshan Anwar, MD, Saeedeh Mirbagheri, MD, YuanYuan Joyce Xie, MD, Nariman Nezami, MD, Jarunee Intrapiromkul, MD, Shuqian Zhang MD, Alvaro Alonso MD PhD, Haitao Chu, PhD, David Couper, PhD, Bruce A. Wasserman, MD

Purpose: To implement a magnetic resonance (MR) imaging protocol to measure intracranial atherosclerotic disease (ICAD) in a population-based multicenter study and report examination and reader reliability of these MR imaging measurements and descriptive statistics representative of the general population.

01 septiembre 2016

SPRINGER. General Anesthesia Versus Conscious Sedation in Acute Stroke Treatment: The Importance of Head Immobilization

H. Janssen, G. Buchholz, M. Killer, L. Ertl, H. Brückmann, J. Lutz

Purpose: While today mechanical thrombectomy is an established treatment option for main branch occlusions in anterior circulation stroke, there is still an ongoing debate on the kind of anesthesia to be preferred. Introducing a simple method for head stabilization, we analyzed safety and duration of endovascular recanalization procedures under general anesthesia (GA) and conscious sedation (CS).

01 agosto 2016

NEUROSURGERY. Comparing Preoperative With Postoperative Stereotactic Radiosurgery for Resectable Brain Metastases: A Multi-institutional Analysis

Patel, Kirtesh R. MD; Burri, Stuart H. MD; Asher, Anthony L. MD; Crocker, Ian R. MD; Fraser, Robert W. MD; Zhang, Chao PhD; Chen, Zhengjia PhD; Kandula, Shravan MD; Zhong, Jim MD; Press, Robert H. MD; Olson, Jeffery J. MD; Oyesiku, Nelson M. MD, PhD; Wait, Scott D. MD; Curran, Walter J. MD; Shu, Hui-Kuo G. MD, PhD; Prabhu, Roshan S. MD, MS

BACKGROUND: Stereotactic radiosurgery (SRS) is an increasingly common modality used with surgery for resectable brain metastases (BM).

01 septiembre 2016

SPRINGER. Neuroradiology. Cerebellar cortical infarct cavities and vertebral artery disease

Laurens J. L. De Cocker, A. Compter, L. J. Kappelle, P. R. Luijten, J. Hendrikse, H. B. Van der Worp

Introduction: Cerebellar cortical infarct cavities are a newly recognised entity associated with atherothromboembolic cerebrovascular disease and worse physical functioning. We aimed to investigate the relationship of cerebellar cortical infarct cavities with symptomatic vertebrobasilar ischaemia and with vascular risk factors.

20 julio 2016

SPRINGER. Neuroradiology. Prediction of upper extremity motor recovery after subacute intracerebral hemorrhage through diffusion tensor imaging: a systematic review and meta-analysis

Pradeep Kuma, Arun Kumar Yadav, Shubham Misra, Amit Kumar, Kamalesh Chakravarty, Kameshwar Prasad

Introduction: Early assessment of the pyramidal tracts is important for intracerebral hemorrhage (ICH) patients in order to decide the optimal treatment or to assess appropriate rehabilitation strategies, and management of patient expectations and goals. The purpose of this study was to systematically review and summarize the current available literature on the value of Fractional Anisotropy (FA) parameter of the diffusion tensor imaging (DTI) in predicting upper extremity (UE) motor recovery after subacute ICH.

20 julio 2016

SPRINGER. Neuroradiology. Wall enhancement on high-resolution magnetic resonance imaging may predict an unsteady state of an intracranial saccular aneurysm

Peng Hu, Qi Yang, Dan-Dan Wang, Shao-Chen Guan, Hong-Qi Zhang

Introduction: The aneurysm wall has been reported to play a critical role in the formation, development, and even rupture of an aneurysm. We used high-resolution magnetic resonance imaging (HRMRI) to investigate the aneurysm wall in an effort to identify evidence of inflammation invasion and define its relationship with aneurysm behavior.

22 julio 2016

SPRINGER. Neuroradiology. Impact of leukoaraiosis on parenchymal hemorrhage in elderly patients treated with thrombolysis

Norbert Nighoghossian, Fatima AbbasTae-Hee Cho, Ana Filipa Geraldo, Vincent Cottaz, Elie Janecek, Laura Mechtouff, Magali Bischoff, Carlos El Khoury, Anne Marie Schott, Laurent Derex, Marc Hermier, Louis Guy Tisserand, Roxana Amelie, Leila Chamard, Yves Berthezene

Introduction: Severity of vascular damage of white matter may predict hemorrhagic transformation (HT). We assess the relationship between leukoaraiosis (LA) severity and the type of hemorrhagic transformation in elderly patients treated with thrombolysis.

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