01 febrero 2013

SPRINGER. MR with surface coils in the follow-up after endoscopic laser resection for glottic squamous cell carcinoma

Marco Ravanelli, Davide Farina, Paola Rizzardi, Elisa Botturi, Paola Prandolini, Stefano Mangili, Giorgio Peretti, Piero Nicolai, Roberto Maroldi

Introduction: This study focuses on the feasibility and diagnostic accuracy of MR of the larynx performed with surface coils after endoscopic laser resection (ELR) for glottic cancer.

01 enero 2013

SPRINGER. The feasibility and efficacy of endovascular treatment for very small or tiny ruptured paraclinoid aneurysms

Jing Xu, Xian-Yi Chen, Ding-Yao Jiang, Wen Li, Jian-Min Zhang

Introduction: The aim of this study was to evaluate the feasibility of endovascular treatment (EVT) for ruptured very small (≤5 mm) or tiny (≤3 mm) paraclinoid aneurysms of the internal carotid artery (ICA).

01 enero 2013

SPRINGER. Stents and flow diverters in the treatment of aneurysms: device deformation in vivo may alter porosity and impact efficacy

Fabrice Bing, Tim E. Darsaut, Igor Salazkin, Alina Makoyeva, Guylaine Gevry, Jean Raymond

Introduction: High-porosity (HP) and flow-diverting (FD) stents are increasingly used to treat intracranial aneurysms. In vivo device deformations and their impact on the porosity of the segment of device lying over the aneurysm neck remain inadequately characterized.

01 enero 2013

SPRINGER. Is general anaesthesia preferable to conscious sedation in the treatment of acute ischaemic stroke with intra-arterial mechanical thrombectomy? A review of the literature

N. John, P. Mitchell, R. Dowling, B. Yan

Introduction: Intra-arterial mechanical thrombectomy (IAMT) is an endovascular technique that allows for the acute retrieval of intravascular thrombi and is increasingly being used for the treatment of acute ischaemic stroke (AIS). There are currently two anaesthetic options during IAMT: general anaesthesia (GA) and conscious sedation (CS). The decision to use GA versus CS is the source of controversy, as it requires careful balance between patient pain, movement and airway protection whilst minimising time delay and haemodynamic fluctuations. This review examines and summarises the evidence for the use of GA versus CS in the treatment of AIS by IAMT.

17 diciembre 2013

STROKE. Reperfusion Injury on Magnetic Resonance Imaging After Carotid Revascularization

A-Hyun Cho, MD, PhD; Yong-Pil Cho, MD, PhD; Deok Hee Lee, MD, PhD; Tae-Won Kwon, MD, PhD; Sun U. Kwon, MD, PhD; Dae-Chul Suh, MD, PhD; Jong S. Kim, MD, PhD; Dong-Wha Kang, MD, PhD

Background and Purpose: Reperfusion injury can be revealed as delayed gadolinium enhancement in the subarachnoid space on a fluid-attenuated inversion recovery image, which is designated as a hyperintense acute reperfusion marker (HARM). We sought to investigate the occurrence and predictors of HARM and its association with new ischemic infarcts after carotid revascularization.

19 diciembre 2013

STROKE. Non-ST–Elevation Myocardial Infarction in Patients Undergoing Carotid Endarterectomy or Carotid Artery Stent Placement

Amir Khan, MD; Malik M. Adil, MD; Adnan I. Qureshi, MD

Background and Purpose: The significance of non-ST–elevation myocardial infarction (NSTEMI) after carotid endarterectomy or carotid angioplasty and stent placement is unknown. We performed this study to identify the frequency of NSTEMI and impact on outcomes related to carotid endarterectomy or carotid artery stent placement in patients treated in a large national cohort.

24 diciembre 2013

STROKE. Predictors of Acute and Persisting Ischemic Brain Lesions in Patients Randomized to Carotid Stenting or Endarterectomy

Ayda Rostamzadeh, MD; Thomas Zumbrunn, PhD; Lisa M. Jongen, MD, PhD; Paul J. Nederkoorn, PhD, MD; Sumaira Macdonald, FRCR; Philippe A. Lyrer, MD; L. Jaap Kappelle, MD; Willem P. Th. M. Mali, MD; Martin M. Brown, FRCP; H. Bart van der Worp, PhD, MD; Stefan T. Engelter, MD; Leo H. Bonati, MD on behalf of the ICSS-MRI Substudy Investigators

Background and Purpose: We investigated predictors for acute and persisting periprocedural ischemic brain lesions among patients with symptomatic carotid stenosis randomized to stenting or endarterectomy in the International Carotid Stenting Study.

26 diciembre 2013

STROKE. Basic Sciences. Roles of Hypertension in the Rupture of Intracranial Aneurysms

Yoshiteru Tada, MD, PhD*; Kosuke Wada, MD*; Kenji Shimada, MD, PhD; Hiroshi Makino, MD; Elena I. Liang, BS; Shoko Murakami, MD, PhD; Mari Kudo, MD; Keiko T. Kitazato, BS; Shinji Nagahiro, MD, PhD; Tomoki Hashimoto, MD

Background and Purpose: Systemic hypertension has long been considered a risk factor of aneurysmal rupture. However, a causal link between systemic hypertension and the development of aneurysmal rupture has not been established. In this study, using a mouse model of intracranial aneurysm rupture, we examined the roles of systemic hypertension in the development of aneurysmal rupture.

09 enero 2014

STROKE. Clinical Sciences. Addition of Hyperacute MRI Aids in Patient Selection, Decreasing the Use of Endovascular Stroke Therapy

Dolora Wisco, MD; Ken Uchino, MD; Maher Saqqur, MD; James M. Gebel, MD; Junya Aoki, MD; Shazia Alam, DO; Pravin George, DO; Christopher R. Newey, DO; Shumei Man, MD; Yohei Tateishi, MD; Julie McNeil, RN; Michelle Winfield, RN; Esteban Cheng-Ching, MD; Ferdinand K. Hui, MD; Gabor Toth, MD; Mark Bain, MD; Peter A. Rasmussen, MD; Thomas Masaryk, MD; Paul Ruggieri, MD; Muhammad Shazam Hussain, MD

Background and Purpose: The failure of recent trials to show the effectiveness of acute endovascular stroke therapy (EST) may be because of inadequate patient selection. We implemented a protocol to perform pretreatment MRI on patients with large-vessel occlusion eligible for EST to aid in patient selection.

12 diciembre 2013

STROKE. Alberta Stroke Program Early Computed Tomography Score to Select Patients for Endovascular Treatment. Interventional Management of Stroke (IMS)-III Trial

Michael D. Hill, MD, FRCPC; Andrew M. Demchuk, MD, FRCPC; Mayank Goyal, MD, FRCPC; Tudor G. Jovin, MD; Lydia D. Foster, MSc; Thomas A. Tomsick, MD; Rüdiger von Kummer, MD; Sharon D. Yeatts, PhD; Yuko Y. Palesch, PhD; Joseph P. Broderick, MD for the IMS3 Investigators

Background and Purpose: The Interventional Management of Stroke (IMS)-III trial randomized patients with acute ischemic stroke to intravenous tissue-type plasminogen activator (tPA) plus endovascular therapy versus intravenous tPA therapy alone within 3 hours from symptom onset. A predefined secondary hypothesis was that subjects with significant early ischemic change on the baseline scan would not respond to endovascular therapy.

05 noviembre 2013

STROKE. Stroke Treatment Academic Industry Roundtable. Research Priorities in the Assessment of Neurothrombectomy Devices

Jeffrey L. Saver, MD; Tudor G. Jovin, MD; Wade S. Smith, MD; Gregory W. Albers, MD for the STAIR VIII Consortium

Background and Purpose: The goal of the Stroke Treatment Academic Industry Roundtable (STAIR) meetings is to advance the development of stroke therapies. At STAIR VIII, consensus recommendations were developed for clinical trial strategies to demonstrate the benefit of endovascular reperfusion therapies for acute ischemic stroke.

10 septiembre 2013

STROKE. Switching Strategy for Mechanical Thrombectomy of Acute Large Vessel Occlusion in the Anterior Circulation

Dong-Hun Kang, MD; Yong-Won Kim, MD; Yang-Ha Hwang, MD; Jaechan Park, MD; Jeong-Hyun Hwang, MD; Yong-Sun Kim, MD

Background and Purpose: We introduce the concept of a switching strategy for mechanical thrombectomy with period-to-period analysis. In period 1, forced arterial suction thrombectomy with a Penumbra reperfusion catheter was performed, even in difficult cases; in period 2, forced arterial suction thrombectomy was initially performed, with switching to Solitaire in difficult cases.

17 octubre 2013

STROKE. Intracranial Stent Placement for Symptomatic Intracranial Stenosis as Part of a Clinical Trial Versus Outside a Clinical Trial

Farhan Siddiq, MD; Malik M. Adil, MD; Kiersten Norby, MD; Adnan I. Qureshi, MD

Background and Purpose: A high rate of postprocedure complications in the Stenting versus Aggressive Medical Therapy for Intracranial Arterial Stenosis (SAMMPRIS) trial has raised concerns whether such results are representative of intracranial stent placement in actual routine practice.

21 noviembre 2013

STROKE. Clinical Sciences. Outcome of Standard and High-Risk Patients With Acute Anterior Circulation Stroke After Stent Retriever Thrombectomy

Pascal P. Gratz, MD*; Simon Jung, MD*; Gerhard Schroth, MD; Jan Gralla, MD; Pasquale Mordasini, MD; Kety Hsieh, MD; Mirjam R. Heldner, MD; Heinrich P. Mattle, MD; Marie-Luise Mono, MD; Urs Fischer, MD; Marcel Arnold, MD*; Christoph Zubler, MD*

Background and Purpose: Stent retrievers have become an important tool for the treatment of acute ischemic stroke. The aim of this study was to analyze outcome and complications in a large cohort of patients with stroke treated with the Solitaire stent retriever. The study also included patients who did not meet standard inclusion criteria for endovascular treatment: low or high baseline National Institutes of Health Stroke Scale score, ≥80 years of age, extensive ischemic signs in middle cerebral artery territory, and time from symptom onset to endovascular intervention >8 hours.

07 noviembre 2013

STROKE. Clinical Sciences. Therapeutic Hypothermia After Recanalization in Patients With Acute Ischemic Stroke

Ji Man Hong, MD, PhD; Jin Soo Lee, MD, PhD; Hee-Jung Song, MD; Hye Seon Jeong, MD; Huimahn Alex Choi, MD; Kiwon Lee, MD

Background and Purpose: Therapeutic hypothermia improves outcomes in experimental stroke models, especially after ischemia-reperfusion injury. We investigated the clinical and radiological effects of therapeutic hypothermia in acute ischemic stroke patients after recanalization.