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ABSTRACT


01 febrero 2014

SPRINGER. Is eptifibatide a safe and effective rescue therapy in thromboembolic events complicating cerebral aneurysm coil embolization? Single-center experience in 42 cases and review of the literature

Jacques Sedat, Yves Chau, Lydiane Mondot, Richard Chemla, Michel Lonjon, Bernard Padovani

Introduction: Thromboembolic complications are the most frequent perioperative complications of endovascular treatment of intracranial aneurysms. Even if the effectiveness of glycoprotein IIb/IIIa inhibitors has been reported, the outcomes in published clinic data are contradictory. This study aims to assess the effectiveness and the safety of eptifibatide in thromboembolic complications during intracranial aneurysm embolization procedure.

01 febrero 2014

SPRINGER. Delayed ipsilateral parenchymal hemorrhage following treatment of intracranial aneurysms with flow diverter

Catherine Tomas, Azzedine Benaissa, Denis Herbreteau, Krzysztof Kadziolka, Laurent Pierot

Introduction: The use of flow diverters (FDs) has shown promising results, particularly in the treatment of large or complex intracranial aneurysms. However, some complications can occur both during and after FD treatment, including delayed ipsilateral parenchymal hemorrhage (DIPH). The clinical presentation, etiopathogeny, and management of this complication are not well understood. We report a series of four patients with DIPH and discuss the potential mechanisms and modalities of treatment.

01 febrero 2013

SPRINGER. Combined use of percutaneous cryoablation and vertebroplasty with 3D rotational angiograph in treatment of single vertebral metastasis: comparison with vertebroplasty

S. Masala, M. Chiocchi, A. Taglieri, A. Bindi, M. Nezzo, D. De Vivo, G. Simonetti

Introduction: This study aims to assess the effectiveness of combined procedure of cryoablation and vertebroplasty (CVT) for reduction of pain and improvement of the quality of life in patients with single painful metastatic vertebral fractures.

01 febrero 2013

SPRINGER. Long-term clinical and radiological results of endovascular internal trapping in vertebral artery dissection

Daina Kashiwazaki, Satoshi Ushikoshi, Takeshi Asano, Satoshi Kuroda, Kiyohiro Houkin

Introduction: Previous reports have suggested that endovascular parent artery occlusion is an effective and safe procedure for the treatment of vertebral artery dissection (VAD). However, the results of long-term outcomes are still unclear. This study reviewed the clinical and imaging outcomes of patients with VAD treated by endovascular internal trapping.

01 febrero 2013

SPRINGER. Peri-stent aneurysm formation following a stent implant for stenotic intracranial vertebral artery dissection: a technical report of two cases successfully treated with coil embolization

Hideki Ishimaru, Kazuaki Nakashima, Hideaki Takahata, Yohjiro Matsuoka

Introduction: Although stenting for stenotic vertebral artery dissection (VAD) improves compromised blood flow, subsequent peri-stent aneurysm (PSA) formation is not well-known. We report two cases with PSA successfully treated with coil embolization.

01 enero 2013

SPRINGER. Stents and flow diverters in the treatment of aneurysms: device deformation in vivo may alter porosity and impact efficacy

Fabrice Bing, Tim E. Darsaut, Igor Salazkin, Alina Makoyeva, Guylaine Gevry, Jean Raymond

Introduction: High-porosity (HP) and flow-diverting (FD) stents are increasingly used to treat intracranial aneurysms. In vivo device deformations and their impact on the porosity of the segment of device lying over the aneurysm neck remain inadequately characterized.

01 enero 2013

SPRINGER. Is general anaesthesia preferable to conscious sedation in the treatment of acute ischaemic stroke with intra-arterial mechanical thrombectomy? A review of the literature

N. John, P. Mitchell, R. Dowling, B. Yan

Introduction: Intra-arterial mechanical thrombectomy (IAMT) is an endovascular technique that allows for the acute retrieval of intravascular thrombi and is increasingly being used for the treatment of acute ischaemic stroke (AIS). There are currently two anaesthetic options during IAMT: general anaesthesia (GA) and conscious sedation (CS). The decision to use GA versus CS is the source of controversy, as it requires careful balance between patient pain, movement and airway protection whilst minimising time delay and haemodynamic fluctuations. This review examines and summarises the evidence for the use of GA versus CS in the treatment of AIS by IAMT.

17 diciembre 2013

STROKE. Reperfusion Injury on Magnetic Resonance Imaging After Carotid Revascularization

A-Hyun Cho, MD, PhD; Yong-Pil Cho, MD, PhD; Deok Hee Lee, MD, PhD; Tae-Won Kwon, MD, PhD; Sun U. Kwon, MD, PhD; Dae-Chul Suh, MD, PhD; Jong S. Kim, MD, PhD; Dong-Wha Kang, MD, PhD

Background and Purpose: Reperfusion injury can be revealed as delayed gadolinium enhancement in the subarachnoid space on a fluid-attenuated inversion recovery image, which is designated as a hyperintense acute reperfusion marker (HARM). We sought to investigate the occurrence and predictors of HARM and its association with new ischemic infarcts after carotid revascularization.

19 diciembre 2013

STROKE. Non-ST–Elevation Myocardial Infarction in Patients Undergoing Carotid Endarterectomy or Carotid Artery Stent Placement

Amir Khan, MD; Malik M. Adil, MD; Adnan I. Qureshi, MD

Background and Purpose: The significance of non-ST–elevation myocardial infarction (NSTEMI) after carotid endarterectomy or carotid angioplasty and stent placement is unknown. We performed this study to identify the frequency of NSTEMI and impact on outcomes related to carotid endarterectomy or carotid artery stent placement in patients treated in a large national cohort.

24 diciembre 2013

STROKE. Predictors of Acute and Persisting Ischemic Brain Lesions in Patients Randomized to Carotid Stenting or Endarterectomy

Ayda Rostamzadeh, MD; Thomas Zumbrunn, PhD; Lisa M. Jongen, MD, PhD; Paul J. Nederkoorn, PhD, MD; Sumaira Macdonald, FRCR; Philippe A. Lyrer, MD; L. Jaap Kappelle, MD; Willem P. Th. M. Mali, MD; Martin M. Brown, FRCP; H. Bart van der Worp, PhD, MD; Stefan T. Engelter, MD; Leo H. Bonati, MD on behalf of the ICSS-MRI Substudy Investigators

Background and Purpose: We investigated predictors for acute and persisting periprocedural ischemic brain lesions among patients with symptomatic carotid stenosis randomized to stenting or endarterectomy in the International Carotid Stenting Study.

26 diciembre 2013

STROKE. Basic Sciences. Roles of Hypertension in the Rupture of Intracranial Aneurysms

Yoshiteru Tada, MD, PhD*; Kosuke Wada, MD*; Kenji Shimada, MD, PhD; Hiroshi Makino, MD; Elena I. Liang, BS; Shoko Murakami, MD, PhD; Mari Kudo, MD; Keiko T. Kitazato, BS; Shinji Nagahiro, MD, PhD; Tomoki Hashimoto, MD

Background and Purpose: Systemic hypertension has long been considered a risk factor of aneurysmal rupture. However, a causal link between systemic hypertension and the development of aneurysmal rupture has not been established. In this study, using a mouse model of intracranial aneurysm rupture, we examined the roles of systemic hypertension in the development of aneurysmal rupture.

09 enero 2014

STROKE. Clinical Sciences. Addition of Hyperacute MRI Aids in Patient Selection, Decreasing the Use of Endovascular Stroke Therapy

Dolora Wisco, MD; Ken Uchino, MD; Maher Saqqur, MD; James M. Gebel, MD; Junya Aoki, MD; Shazia Alam, DO; Pravin George, DO; Christopher R. Newey, DO; Shumei Man, MD; Yohei Tateishi, MD; Julie McNeil, RN; Michelle Winfield, RN; Esteban Cheng-Ching, MD; Ferdinand K. Hui, MD; Gabor Toth, MD; Mark Bain, MD; Peter A. Rasmussen, MD; Thomas Masaryk, MD; Paul Ruggieri, MD; Muhammad Shazam Hussain, MD

Background and Purpose: The failure of recent trials to show the effectiveness of acute endovascular stroke therapy (EST) may be because of inadequate patient selection. We implemented a protocol to perform pretreatment MRI on patients with large-vessel occlusion eligible for EST to aid in patient selection.

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