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ABSTRACT


01 enero 2014

THE LANCET NEUROLOGY. Development of the PHASES score for prediction of risk of rupture of intracranial aneurysms: a pooled analysis of six prospective cohort studies

Dr Jacoba P Greving PhD, Marieke J H Wermer MD b, Prof Robert D Brown MD c, Prof Akio Morita MD d e, Seppo Juvela MD f, Masahiro Yonekura MD g, Toshihiro Ishibashi MD h, Prof James C Torner PhD i, Prof Takeo Nakayama MD j, Prof Gabriël J E Rinkel MD k, Prof Ale Algra MD

Background: The decision of whether to treat incidental intracranial saccular aneurysms is complicated by limitations in current knowledge of their natural history. We combined individual patient data from prospective cohort studies to determine predictors of aneurysm rupture and to construct a risk prediction chart to estimate 5-year aneurysm rupture risk by risk factor status.

01 enero 2014

SPRINGER. Computed tomography angiography intraluminal filling defect is predictive of internal carotid artery free-floating thrombus

A. Jaberi, C. Lum, P. Stefanski, R. Thornhill, D. Iancu, W. Petrcich, F. Momoli, C. Torres, D. Dowlatshahi

Introduction: Filling defects at the internal carotid artery (ICA) origin in the work-up of stroke or transient ischemic attack may be an ulcerated plaque or free-floating thrombus (FFT). This may be challenging to distinguish, as they can appear morphologically similar. This is an important distinction as FFT can potentially embolize distally, and its management differs. We describe a series of patients with suspected FFT and evaluate its imaging appearance, clinical features, and evolution with therapy.

01 enero 2014

SPRINGER. First demonstration of resolution of an infundibulum by direct treatment of the arterial wall with Pipeline flow-diverting stent

M. M. Kameda-Smith, J. C. Du Plessis, J. J. Bhattacharya

Introduction: Infundibula are symmetrical funnel-shaped widening, measuring more than 3 mm at its base with the branch artery arising from its apex. The pathological significance of this entity remains controversial. Although a relatively common appearance in otherwise normal angiograms, they have occasionally been described to progress into saccular aneurysms or directly rupture.

01 enero 2014

SPRINGER. Clinical significance of post-interventional cerebral hyperdensities after endovascular mechanical thrombectomy in acute ischaemic stroke

Omid Nikoubashman, Arno Reich, Mirco Gindullis, Katharina Frohnhofen, Rastislav Pjontek, Marc-Alexander Brockmann, Jörg B. Schulz, Martin Wiesmann

Introduction: This study aims to investigate the clinical significance of post-interventional cerebral hyperdensities (PCHD) after endovascular mechanical thrombectomy in acute ischaemic stroke.

01 enero 2014

SPRINGER. Treatment of elastase-induced intracranial aneurysms in New Zealand white rabbits by use of a novel neurovascular embolization stent device

Anna Luisa Kühn, Christian Roth, Bernd Romeike, Iris Quasar Grunwald

Introduction: This study aims to test a novel balloon expandable stent covered with a polytetrafluoroethylene membrane (neurovascular embolization cover (NEC), NFocus Neuromedical, Palo Alto, California) regarding angiographic and histologic aneurysm occlusion. Radiopacity, stent placement, navigation, flexibility, and intimal proliferation were also evaluated.

01 febrero 2014

SPRINGER. Evaluation of a newly designed flow diverter for the treatment of intracranial aneurysms in an elastase-induced aneurysm model, in New Zealand white rabbits

Andreas Simgen, Desiree Ley, Christian Roth, Umut Yilmaz, Heiko Körner, Ruben Mühl-Benninghaus, Yoo-Jin Kim, Bruno Scheller, Wolfgang Reith

Introduction: In this study, we analyzed angiographic and histologic aneurysm occlusion of a newly designed flow-diverting device. Visibility and flexibility, as well as occlusions of side branches and neointimal proliferation were also evaluated.

01 febrero 2014

SPRINGER. Nationwide survey of the nature and risk factors of complications in embolization of meningiomas and other intracranial tumors: Japanese Registry of NeuroEndovascular Therapy 2 (JR-NET2)

Tomohito Hishikawa, Kenji Sugiu, Masafumi Hiramatsu, Jun Haruma, Koji Tokunaga, Isao Date, Nobuyuki Sakai

Introduction: Embolization of intracranial tumor is widely performed in Japan, mainly before neurosurgical resection. A retrospective, multicenter, observational study in Japan was conducted to clarify the nature, frequency, and risk factors of complications in intracranial tumor embolization.

01 febrero 2014

SPRINGER. Is eptifibatide a safe and effective rescue therapy in thromboembolic events complicating cerebral aneurysm coil embolization? Single-center experience in 42 cases and review of the literature

Jacques Sedat, Yves Chau, Lydiane Mondot, Richard Chemla, Michel Lonjon, Bernard Padovani

Introduction: Thromboembolic complications are the most frequent perioperative complications of endovascular treatment of intracranial aneurysms. Even if the effectiveness of glycoprotein IIb/IIIa inhibitors has been reported, the outcomes in published clinic data are contradictory. This study aims to assess the effectiveness and the safety of eptifibatide in thromboembolic complications during intracranial aneurysm embolization procedure.

01 febrero 2014

SPRINGER. Delayed ipsilateral parenchymal hemorrhage following treatment of intracranial aneurysms with flow diverter

Catherine Tomas, Azzedine Benaissa, Denis Herbreteau, Krzysztof Kadziolka, Laurent Pierot

Introduction: The use of flow diverters (FDs) has shown promising results, particularly in the treatment of large or complex intracranial aneurysms. However, some complications can occur both during and after FD treatment, including delayed ipsilateral parenchymal hemorrhage (DIPH). The clinical presentation, etiopathogeny, and management of this complication are not well understood. We report a series of four patients with DIPH and discuss the potential mechanisms and modalities of treatment.

01 febrero 2013

SPRINGER. Combined use of percutaneous cryoablation and vertebroplasty with 3D rotational angiograph in treatment of single vertebral metastasis: comparison with vertebroplasty

S. Masala, M. Chiocchi, A. Taglieri, A. Bindi, M. Nezzo, D. De Vivo, G. Simonetti

Introduction: This study aims to assess the effectiveness of combined procedure of cryoablation and vertebroplasty (CVT) for reduction of pain and improvement of the quality of life in patients with single painful metastatic vertebral fractures.

01 febrero 2013

SPRINGER. Long-term clinical and radiological results of endovascular internal trapping in vertebral artery dissection

Daina Kashiwazaki, Satoshi Ushikoshi, Takeshi Asano, Satoshi Kuroda, Kiyohiro Houkin

Introduction: Previous reports have suggested that endovascular parent artery occlusion is an effective and safe procedure for the treatment of vertebral artery dissection (VAD). However, the results of long-term outcomes are still unclear. This study reviewed the clinical and imaging outcomes of patients with VAD treated by endovascular internal trapping.

01 febrero 2013

SPRINGER. Peri-stent aneurysm formation following a stent implant for stenotic intracranial vertebral artery dissection: a technical report of two cases successfully treated with coil embolization

Hideki Ishimaru, Kazuaki Nakashima, Hideaki Takahata, Yohjiro Matsuoka

Introduction: Although stenting for stenotic vertebral artery dissection (VAD) improves compromised blood flow, subsequent peri-stent aneurysm (PSA) formation is not well-known. We report two cases with PSA successfully treated with coil embolization.

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