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ABSTRACT


29 mayo 2014

STROKE. Clinical Sciences. Predictors of Functional Dependence Despite Successful Revascularization in Large-Vessel Occlusion Strokes

Zhong-Song Shi, MD; David S. Liebeskind, MD; Bin Xiang, PhD; Sijian Grace Ge, MS; Lei Feng, MD; Gregory W. Albers, MD; Ronald Budzik, MD; Thomas Devlin, MD; Rishi Gupta, MD; Olav Jansen, MD; Tudor G. Jovin, MD; Monika Killer-Oberpfalzer, MD; Helmi L. Lutsep, MD; Juan Macho, MD; Raul G. Nogueira, MD; Marilyn Rymer, MD; Wade S. Smith, MD; Nils Wahlgren, MD; Gary R. Duckwiler, MD; for the Multi MERCI, TREVO, and TREVO 2 Investigators

Background and Purpose: High revascularization rates in large-vessel occlusion strokes treated by mechanical thrombectomy are not always associated with good clinical outcomes. We evaluated predictors of functional dependence despite successful revascularization among patients with acute ischemic stroke treated with thrombectomy.

12 junio 2014

STROKE. Clinical Sciences. Impact of Diffusion-Weighted Imaging Alberta Stroke Program Early Computed Tomography Score on the Success of Endovascular Reperfusion Therapy

Manabu Inoue, MD, PhD*; Jean-Marc Olivot, MD, PhD*; Julien Labreuche, BST; Michael Mlynash, MD, MS; Waimea Tai, MD; Jean-François Albucher, MD; Elena Meseguer, MD; Pierre Amarenco, MD; Mikael Mazighi, MD, PhD

Background and Purpose: In acute ischemic stroke patients treated by intravenous thrombolysis, a diffusion-weighted imaging (DWI) Alberta Stroke Program Early Computed Tomography Score (ASPECTS) is an independent factor of functional outcomes. Our aim was to assess the impact of pretreatment DWI-ASPECTS on outcomes after endovascular therapy, with a specific emphasis on recanalization.

22 mayo 2014

STROKE. Clinical Sciences. Capillary Index Score in the Interventional Management of Stroke Trials I and II

Firas Al-Ali, MD; Thomas A. Tomsick, MD; John J. Connors III, MD; James M. Gebel, MD; John J. Elias, PhD; Georges Z. Markarian, MD; Zein Al-Ali; Joseph P. Broderick, MD

Background and Purpose: The Capillary Index Score (CIS) is a simple angiography-based scale for assessing viable tissue in the ischemic territory. We retrospectively applied it to Interventional Management of Stroke (IMS) trials I and II to evaluate the predictive value for good outcomes.

29 mayo 2014

STROKE. Clinical Sciences. Unexplained Early Neurological Deterioration After Intravenous Thrombolysis

Pierre Seners, MSc*; Guillaume Turc, MD*; Marie Tisserand, MD; Laurence Legrand, MD; Marc-Antoine Labeyrie, MD; David Calvet, PhD; Jean-François Meder, PhD; Jean-Louis Mas, MD; Catherine Oppenheim, PhD; Jean-Claude Baron, ScD

Background and Purpose: Early neurological deterioration (END) after anterior circulation stroke is a serious clinical event strongly associated with poor outcome. Regarding specifically END occurring within 24 hours of intravenous recombinant tissue-type plasminogen activator, apart from definite causes such as symptomatic intracranial hemorrhage and malignant edema whose incidence, predictors, and clinical management are well established, little is known about END without clear mechanism (ENDunexplained).

10 junio 2014

STROKE. Clinical Sciences. Length of Occlusion Predicts Recanalization and Outcome After Intravenous Thrombolysis in Middle Cerebral Artery Stroke

Vladimir Rohan, MD, PhD; Jan Baxa, MD, PhD; Radek Tupy, MD; Lenka Cerna, MD; Petr Sevcik, MD, PhD; Michal Friesl, Dipl Ing; Jiri Polivka Jr, Dipl Ing; Jiri Polivka, MD, PhD; Jiri Ferda, MD, PhD

Background and Purpose: The length of large vessel occlusion is considered a major factor for therapy in patients with ischemic stroke. We used 4D-CT angiography evaluation of middle cerebral artery occlusion in prediction of recanalization and favorable clinical outcome and after intravenous thrombolysis (IV-tPA).

15 mayo 2014

STROKE. Clinical Sciences. Optimal Workflow and Process-Based Performance Measures for Endovascular Therapy in Acute Ischemic Stroke

Bijoy K. Menon, MD; Mohammed A. Almekhlafi, MD, MSc; Vitor Mendes Pereira, MD, MSc; Jan Gralla, MD; Alain Bonafe, MD; Antoni Davalos, MD; Rene Chapot, MD; Mayank Goyal, MD; on behalf of the STAR Study Investigators

Background and Purpose: We report on workflow and process-based performance measures and their effect on clinical outcome in Solitaire FR Thrombectomy for Acute Revascularization (STAR), a multicenter, prospective, single-arm study of Solitaire FR thrombectomy in large vessel anterior circulation stroke patients.

29 mayo 2014

STROKE. Clinical Sciences. Impact of Collaterals on Successful Revascularization in Solitaire FR With the Intention for Thrombectomy

David S. Liebeskind, MD; Reza Jahan, MD; Raul G. Nogueira, MD; Osama O. Zaidat, MD; Jeffrey L. Saver, MD; for the SWIFT Investigators

Background and Purpose: Collaterals at angiography before endovascular therapy were analyzed to ascertain the effect on a novel end point of successful revascularization without symptomatic hemorrhage in the Solitaire FR With the Intention for Thrombectomy (SWIFT) study.

15 mayo 2014

STROKE. Warfarin-Associated Intracerebral Hemorrhage After Ischemic Stroke

Signild Åsberg, MD, PhD; Marie Eriksson, PhD; Karin M. Henriksson, MD, PhD; Andreas Terént, MD, PhD

Background and Purpose: The aim was to investigate the risk of intracerebral hemorrhage (ICH) in patients with ischemic stroke taking warfarin and whether this risk changed over time.

01 mayo 2014

STROKE. Clinical Sciences. Long-Term Outcome of 106 Consecutive Pediatric Ruptured Brain Arteriovenous Malformations After Combined Treatment

Thomas Blauwblomme, MD; Marie Bourgeois, MD; Philippe Meyer, MD; Stéphanie Puget, MD, PhD; Federico Di Rocco, MD, PhD; Nathalie Boddaert, MD, PhD; Michel Zerah, MD, PhD; Francis Brunelle, MD, PhD; Christian Sainte Rose, MD, PhD; Olivier Naggara, MD, PhD

Background and Purpose: Childhood intracerebral hemorrhage is mainly attributable to underlying brain arteriovenous malformations (bAVMs). Multimodal treatment options for bAVMs include microsurgery and embolization, allowing an immediate cure, and radiosurgery, entailing longer obliteration times. Follow-up data on pediatric ruptured bAVMs are scarce, making it difficult to assess the risk of subsequent intracerebral hemorrhage. Our aim was to assess the clinical and angiographic outcome and to analyze risk factors for rebleeding during and after combined treatment of pediatric bAVMs.

01 junio 2014

SPRINGER. Aneurysmal wall enhancement and perianeurysmal edema after endovascular treatment of unruptured cerebral aneurysms

I-Chang Su, Robert A. Willinsky, Noel F. Fanning, Ronit Agid

Introduction: Perianeurysmal edema and aneurysm wall enhancement are previously described phenomenon after coil embolization attributed to inflammatory reaction. We aimed to demonstrate the prevalence and natural course of these phenomena in unruptured aneurysms after endovascular treatment and to identify factors that contributed to their development.

01 julio 2013

SPRINGER. Impact of a new metal artefact reduction algorithm in the noninvasive follow-up of intracranial clips, coils, and stents with flat-panel angiographic CTA: initial results

Marios-Nikos Psychogios, Bernhard Scholz, Christopher Rohkohl, Yiannis Kyriakou, Alexander Mohr, Peter Schramm, Dorothee Wachter, Katrin Wasser, Michael Knauth

Introduction: Flat-panel angiographic CT after intravenous contrast agent application (ivACT) is increasingly used as a follow-up examination after coiling, clipping, or stenting. The purpose of this study was to evaluate the feasibility of a new metal artefact reduction algorithm (MARA) in patients treated for intracranial aneurysms and stenosis.

01 julio 2013

SPRINGER. Stent-assisted coil embolization of wide-necked posterior inferior cerebellar artery aneurysms

Young Dae Cho, Hyun-Seung Kang, Woong Jae Lee, Kang Min Kim, Jeong Eun Kim, Moon Hee Han

Introduction: Endovascular coil embolization of posterior circulation aneurysms has advantages over a surgical approach. However, the application of coil embolization is sometimes limited in wide-necked posterior inferior cerebellar artery (PICA) aneurysms, which are incorporating the origin of the branch. Presented here is a series of patients who were subjected to stent-supported coil embolization of PICA aneurysms.

01 junio 2013

SPRINGER. Cerebral microbleeds: a guide to detection and clinical relevance in different disease settings

Andreas Charidimou, Anant Krishnan, David J. Werring, H. Rolf Jäger

Abstract: Cerebral microbleeds have emerged as an important new imaging marker of cerebral small vessel disease. With the development of MRI techniques that are exquisitely sensitive to paramagnetic blood products, such as T2*-weighted gradient-recalled echo and susceptibility-weighted sequences, microbleeds have been detected in ever-increasing numbers of patients in stroke and cognitive clinics, as well as in healthy older people and in a variety of other rarer diseases and syndromes. Detection of cerebral microbleeds has clinical implications with respect to the diagnosis of the underlying small vessel disease, the safety of antithrombotic use, and the risk of symptomatic intracerebral haemorrhage, cognitive impairment and dementia. This article provides a guide to the detection and clinical relevance of cerebral microbleeds in different conditions based on a comprehensive review of the literature and own findings in research and clinical practice.

01 junio 2013

SPRINGER. Angiographic CT: in vitro comparison of different carotid artery stents—does stent orientation matter?

Michael Lettau, Martin Bendszus, Stefan Hähnel

Introduction: Our aim was to evaluate the in vitro visualization of different carotid artery stents on angiographic CT (ACT). Of particular interest was the influence of stent orientation to the angiography system by measurement of artificial lumen narrowing (ALN) caused by the stent material within the stented vessel segment to determine whether ACT can be used to detect restenosis within the stent.

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