01 julio 2014

STROKE. Brief Report. Hemodynamic Quantification in Brain Arteriovenous Malformations With Time-Resolved Spin-Labeled Magnetic Resonance Angiography

Hélène Raoult, MD; Elise Bannier, PhD; Pierre Maurel, PhD; Clément Neyton, MS; Jean-Christophe Ferré, MD, PhD; Peter Schmitt, PhD; Christian Barillot, PhD; Jean-Yves Gauvrit, MD, PhD

Background and Purpose: Unenhanced time-resolved spin-labeled magnetic resonance angiography enables hemodynamic quantification in arteriovenous malformations (AVMs). Our purpose was to identify quantitative parameters that discriminate among different AVM components and to relate hemodynamic patterns with rupture risk.

08 julio 2014

STROKE. Clinical Sciences. Family History as a Risk Factor for Carotid Artery Stenosis

Mahyar Khaleghi, MD; Iyad N. Isseh, MBBS; Hayan Jouni, MD; Sunghwan Sohn, PhD; Kent R. Bailey, PhD; Iftikhar J. Kullo, MD

Background and Purpose: We investigated whether family history of stroke or coronary heart disease (CHD) is associated with presence of carotid artery stenosis (CAS).

05 junio 2014

STROKE. Clinical Sciences. Cognitive Deterioration in Bilateral Asymptomatic Severe Carotid Stenosis

Laura Buratti, MD; Clotilde Balucani, MD; Giovanna Viticchi, MD; Lorenzo Falsetti, MD; Claudia Altamura, MD; Emma Avitabile, MD; Leandro Provinciali, MD; Fabrizio Vernieri, MD; Mauro Silvestrini, MD

Background and Purpose: This study aimed to monitor cognitive performance during a 3-year period in subjects with bilateral asymptomatic severe internal carotid artery stenosis and to explore the role of cerebral hemodynamics and atherosclerotic disease in the development of cognitive dysfunction.

01 octubre 2014

NEUROSURGERY. Pipeline Embolization Device for the Treatment of Intra- and Extracranial Fusiform and Dissecting Aneurysms: Initial Experience and Long-term Follow-up

Fischer, Sebastian MD*,‡; Perez, Marta Aguilar MD*; Kurre, Wiebke MD*; Albes, Guido MD*; Bäzner, Hansjörg MD§; Henkes, Hans MD*,¶

Background: Flow-diverting stents offer a promising treatment option for complex aneurysms.

01 octubre 2014

NEUROSURGERY. Comparison of Long-term Outcomes Associated With Endovascular Treatment vs Surgical Treatment Among Medicare Beneficiaries With Unruptured Intracranial Aneurysms

Qureshi, Adnan I. MD; Chaudhry, Saqib A. MD; Tekle, Wondwossen G. MD; Suri, M. Fareed K. MD

Background: Long-term outcomes associated with endovascular and surgical treatments for unruptured intracranial aneurysms are not well studied to date.

01 octubre 2014

NEUROSURGERY. Feasibility and Safety of Pipeline Embolization Device in Patients With Ruptured Carotid Blister Aneurysms

Yoon, Jang W. MD, MS*; Siddiqui, Adnan H. MD‡; Dumont, Travis M. MD‡,§; Levy, Elad I. MD‡; Hopkins, L. Nelson MD‡; Lanzino, Giuseppe MD¶; Lopes, Demetrius K. MD‖; Moftakhar, Roham MD‖; Billingsley, Joshua T. MD‖; Welch, Babu G. MD#; Boulos, Alan S. MD**; Yamamoto, Junichi MD, PhD**; Tawk, Rabih G. MD*; Ringer, Andrew J. MD‡‡; Hanel, Ricardo A. MD, PhD*,§§; for the Endovascular Neurosurgery Research Group

Background: Treatment of internal carotid ruptured blister aneurysms (IC-RBA) presents many challenges to neurosurgeons because of the high propensity for rebleeding during intervention. The role of a Pipeline Embolization Device (PED) in the treatment of this challenging aneurysm subtype remains undefined despite theoretical advantages.

01 octubre 2014

NEUROSURGERY. Impact of Indocyanine Green Videoangiography on Rate of Clip Adjustments Following Intraoperative Angiography

Caplan, Justin M. MD*; Sankey, Eric BS*; Yang, Wuyang MD*; Radvany, Martin G. MD*,‡,§; Colby, Geoffrey P. MD, PhD*,‡,§; Coon, Alexander L. MD*,‡,§; Tamargo, Rafael J. MD*,¶; Huang, Judy MD*

Background: Intraoperative angiography (IA) is used to evaluate the adequacy of clip reconstruction of intracranial aneurysms. Alternative imaging such as indocyanine green videoangiography (ICG-VA) has been proposed. The additional benefit of ICG-VA when IA is routinely used has not been previously determined.

02 septiembre 2014

STROKE. Clinical Sciences. Coated-Platelets Improve Prediction of Stroke and Transient Ischemic Attack in Asymptomatic Internal Carotid Artery Stenosis

Angelia C. Kirkpatrick, MD, MPH; Alfonso J. Tafur, MD, MS; Andrea S. Vincent, PhD; George L. Dale, PhD; Calin I. Prodan, MD

Background and Purpose: Coated-platelets, a subset of procoagulant platelets observed on dual agonist stimulation with collagen and thrombin, support a robust prothrombinase activity and provide a unique measure of platelet thrombotic potential. Coated-platelet levels are increased in large artery stroke, and higher levels are associated with early stroke recurrence, suggesting a potential role for risk stratification in asymptomatic patients with carotid artery stenosis.

26 agosto 2014

STROKE. Contrast-Enhanced Ultrasound for the Evaluation of Neovascularization in Atherosclerotic Carotid Artery Plaques

Kozue Saito, MD; Kazuyuki Nagatsuka, MD; Hatsue Ishibashi-Ueda, MD; Akihiro Watanabe, MD; Hideaki Kannki, MD; Koji Iihara, MD

Background and Purpose: Neovascularization associated with plaque vulnerability, particularly in the plaque shoulder, is susceptible to rupture, causing ischemic events. We aimed to use contrast-enhanced ultrasound to evaluate neovessels in carotid plaques quantitatively, focusing on plaque shoulders.

12 agosto 2014

STROKE. Clinical Sciences. Number of Cerebral Microbleeds and Risk of Intracerebral Hemorrhage After Intravenous Thrombolysis

Steffen Dannenberg*; Jan F. Scheitz, MD*; Michal Rozanski, MD; Hebun Erdur, MD; Peter Brunecker, Dr rer medic; David J. Werring, PhD; Jochen B. Fiebach, MD; Christian H. Nolte, MD

Background and Purpose: Cerebral microbleeds (CMBs) are found in a substantial proportion of patients with ischemic stroke eligible for treatment with intravenous thrombolysis. Until now, there is limited data on the impact of multiple CMBs on occurrence of intracerebral hemorrhage (ICH) after intravenous thrombolysis.

28 agosto 2014

STROKE. Clinical Sciences. Morphological, Hemodynamic, and Clinical Independent Risk Factors for Anterior Communicating Artery Aneurysms

Wojciech Kaspera, MD; Piotr Ładziński, MD, PhD; Patrycja Larysz, MD; Anna Hebda, MS; Krzysztof Ptaszkiewicz, MD; Marek Kopera, MD; Dawid Larysz, MD, PhD

Background and Purpose: The pathogenesis of cerebral aneurysms still raises some controversies. The aim of this study was to identify morphological, hemodynamic, and clinical independent risk factors for anterior communicating artery (ACoA) aneurysm development.

22 julio 2014

STROKE. Clinical Sciences. Flow Diversion Versus Conventional Treatment for Carotid Cavernous Aneurysms

Mario Zanaty, MD; Nohra Chalouhi, MD; Robert M. Starke, MD; Guilherme Barros, BS; Mark Philip Saigh, BA; Eric Winthrop Schwartz, BS; Norman Ajiboye, MD; Stavropoula I. Tjoumakaris, MD; David Hasan, MD; Robert H. Rosenwasser, MD; Pascal Jabbour, MD

Background and Purpose: Several endovascular treatment options are available for cavernous carotid aneurysms. We compared pipeline embolization device (PED) versus conventional endovascular treatment in terms of evolution of mass effect, complications, recurrence, and retreatment rate.

31 julio 2014

STROKE. Clinical Sciences. Long-Term Follow-Up Study of Endarterectomy Versus Angioplasty in Patients With Symptomatic Severe Carotid Stenosis Trial

Jean-Louis Mas, MD; Caroline Arquizan, MD; David Calvet, PhD; Alain Viguier, MD; Jean-François Albucher, MD; Philippe Piquet, MD; Pierre Garnier, MD; Fausto Viader, MD; Maurice Giroud, MD; Hassan Hosseini, PhD; Grégoire Hinzelin, MD; Pascal Favrole, MD; Hilde Hénon, MD; Jean-Philippe Neau, MD; Xavier Ducrocq, MD; Raymond Padovani, MD; Loic Milandre, MD†; François Rouanet, MD; Valérie Wolff, MD; Denis Saudeau, MD; Marie-Hélène Mahagne, MD; Denis Sablot, MD; Pierre Amarenco, MD; Vincent Larrue, MD; Bernard Beyssen, MD; Didier Leys, PhD; Thierry Moulin, MD; Michel Lièvre, MD; Gilles Chatellier, MD; on behalf of the EVA-3S Investigators

Background and Purpose: We aimed at comparing the long-term benefit–risk balance of carotid stenting versus endarterectomy for symptomatic carotid stenosis.

01 agosto 2014

JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY. Endovascular Procedures versus Intravenous Thrombolysis in Stroke with Tandem Occlusion of the Anterior Circulation

Serdar Tütüncü, MD, Jan F. Scheitz, MD , Georg Bohner, MD , Jochen B. Fiebach, MD , Matthias Endres, MD , Christian H. Nolte, MD

Purpose: Stroke with tandem occlusion within the anterior circulation presents a lower probability of recanalization and good clinical outcome after intravenous (IV) thrombolysis than stroke with single occlusion. The present study describes the impact of endovascular procedures (EPs) compared with IV thrombolysis alone on recanalization and clinical outcome.

01 mayo 2014

STROKE. Clinical Sciences. Activities of Daily Living Is a Critical Factor in Predicting Outcome After Carotid Endarterectomy in Asymptomatic Patients

Anand Dayama, MD; Pratik Pimple, MBBS, MPH; Barath Badrinathan, MD; Richard Lee, MD; James G. Reeves, MD

Background and Purpose: Ability to perform basic daily activity represented by functional status (FNS) before surgery can be assessed in the clinic for determining health status of the patient. We sought to study the effect of FNS on postoperative outcomes after carotid endarterectomy (CEA) in a national data set.