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ABSTRACT


17 abril 2014

SPRINGER. Coil embolization of intracranial saccular aneurysms using the Low-profile Visualized Intraluminal Support (LVIS™) device

Young Dae Cho, Chul-Ho Sohn, Hyun-Seung Kang, Jeong Eun Kim, Won-Sang Cho, Gyojun Hwang, O-Ki Kwon, Mi-Sun Ko, Nam-Mi Park, Moon Hee Han

Introduction: The novel Low-profile Visualized Intraluminal Support (LVIS™, LVIS and LVIS Jr.) device was recently introduced for stent-supported coil embolization of intracranial aneurysms. Periprocedural and midterm follow-up results for its use in stent-supported coil embolization of unruptured aneurysms are presented herein.

23 abril 2014

SPRINGER. Microguidewire protection of wide-necked aneurysms incorporating orifices of tortuous acute-angled vessels: a novel approach

Young Dae Cho, Hyun-Seung Kang, Jeong Eun Kim, Jun Hyong Ahn, Seung Chai Jung, Chang Hun Kim, Moon Hee Han

Introduction: Protective/remodeling techniques for treating wide-necked intracranial aneurysms are constantly sought. However, their utility may be limited in lesions that incorporate the orifice of acute-angled efferent branch vessels. Furthermore, passage of a protective microcatheter may be challenging if a small branch is extremely tortuous. This study was conducted to explore a novel method of treating wide-necked aneurysms, utilizing microguidewire protection.

26 abril 2014

SPRINGER. Alcohol percutaneous neurolysis of the sphenopalatine ganglion in the management of refractory cranio-facial pain

Adrian Kastler, Gilles Cadel, Alexandre Comte, Guillaume Gory, Veronique Piccand, Laurent Tavernier, Bruno Kastler

Introduction: The sphenopalatine ganglion (SPN) has been proven to be involved in various types of facial pain syndromes. Management of these cranio-facial pain syndromes can be challenging, and existing specific treatments are sometimes inefficient and may fail. The purpose of this study is to describe and evaluate alcohol SPN in the management of cranio-facial pain.

15 julio 2014

STROKE. Clinical Sciences. Clinical Features and Outcomes of Spinal Cord Arteriovenous Malformations

Young-Jun Lee, MD, PhD; Karel G. Terbrugge, MD, FRCP(C); Guillaume Saliou, MD, PhD; Timo Krings, MD, PhD, FRCP(C)

Background and Purpose: As a result of the rarity of spinal cord arteriovenous malformations (AVM), there are only a few series available that describe clinical features, outcome after treatment, and natural history of these lesions. In this article, we aim to describe our experience with both nidus- and fistulous-type spinal cord AVMs.

07 octubre 2014

STROKE. Major Clinical Trial. Transcranial Laser Therapy in Acute Stroke Treatment

Werner Hacke, MD, PhD; Peter D. Schellinger, MD; Gregory W. Albers, MD; Natan M. Bornstein, MD; Bjorn L. Dahlof, MD; Rachael Fulton, PhD; Scott E. Kasner, MD; Ashfaq Shuaib, MD; Steven P. Richieri, MD; Stephen G. Dilly, MD; Justin Zivin, MD, PhD; Kennedy R. Lees, MD; for the NEST 3 Committees and Investigators

Background and Purpose: On the basis of phase II trials, we considered that transcranial laser therapy could have neuroprotective effects in patients with acute ischemic stroke.

09 septiembre 2014

STROKE. Clinical Sciences. Natural History and Outcome After Treatment of Unruptured Intradural Fusiform Aneurysms

Raphael H. Sacho, MD, FRCS(Eng); Guillaume Saliou, MD, PhD; Alex Kostynskyy, MBBS; Ravi Menezes, PhD; Michael Tymianski, MD, PhD; Timo Krings, MD, PhD; Ivan Radovanovic, MD, PhD; Karel Terbrugge, MD; Gabriel J.E. Rinkel, MD; Robert Willinsky, MD

Background and Purpose: Management of unruptured fusiform intracranial aneurysms is controversial because of the paucity of natural history data. We studied their natural history and outcome after treatment.

09 octubre 2014

STROKE. Clinical Sciences. Incidence and Risk Factors for Diffusion-Weighted Imaging (+) Lesions After Intracranial Stenting and Its Relationship With Symptomatic Ischemic Complications

Keun Young Park, MD; Byung Moon Kim, MD; Dong Joon Kim, MD; Dong Ik Kim, MD; Ji Hoe Heo, MD; Hyo Suk Nam, MD; Young Dae Kim, MD; Dongbeom Song, MD

Background and Purpose. Little is known about high-signal lesions in magnetic resonance diffusion-weighted imaging (DWI [+]) after stenting for intracranial atherosclerotic stenosis. This study aimed to evaluate the incidence, distribution, risk factors, and clinical implications of DWI (+) after intracranial stenting.

09 octubre 2014

STROKE. Clinical Sciences. Comparative Effectiveness of Carotid Revascularization Therapies

Robert J. McDonald, MD, PhD; Jennifer S. McDonald, PhD; Terry M. Therneau, PhD; Giuseppe Lanzino, MD; David F. Kallmes, MD; Harry J. Cloft, MD, PhD

Background and Purpose. Clinical equipoise of carotid revascularization therapies remains controversial. We sought to determine whether adverse outcomes after carotid endarterectomy (CEA) or carotid angioplasty and stenting (CAS) were similar using propensity score–matched analysis of retrospective data from a large hospital discharge database.

25 septiembre 2014

STROKE. Clinical Sciences. Complication Rates and Center Enrollment Volume in the Carotid Revascularization Endarterectomy Versus Stenting Trial

Nicole R. Gonzales, MD; Bart M. Demaerschalk, MD; Jenifer H. Voeks, PhD; MeeLee Tom, MS; George Howard, DrPH; Alice J. Sheffet, PhD; Lawrence Garcia, MD; Daniel G. Clair, MD; John Barr, MD; Steven Orlow, MD; Thomas G. Brott, MD; on behalf of the CREST Investigators

Background and Purpose: Evidence indicates that center volume of cases affects outcomes for both carotid endarterectomy and stenting. We evaluated the effect of enrollment volume by site on complication rates in the Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST).

11 septiembre 2014

STROKE. Clinical Sciences. Picking the Good Apples

George Howard, DrPH; Jenifer H. Voeks, PhD; James F. Meschia, MD; Virginia J. Howard, PhD; Thomas G. Brott, MD

Background and Purpose: The Carotid Revascularization Endarterectomy Versus Stenting Trial was completed with a low stroke and death rate. A lead-in series of patients receiving carotid artery stenting was used to select the physician-operators for the study, where performance was evaluated by complication rates and by peer review of cases. Herein, we assess the potential contribution of statistical evaluation of complication rates.

01 septiembre 2014

STROKE. Effects of Extracranial Carotid Stenosis on Intracranial Blood Flow

Sophia F. Shakur, MD; Tomas Hrbac, MD, PhD; Ali Alaraj, MD; Xinjian Du, MD; Victor A. Aletich, MD; Fady T. Charbel, MD; Sepideh Amin-Hanjani, MD

Background and Purpose: The hemodynamic effects of extracranial carotid stenosis on intracranial blood flow are not well characterized. We sought to determine the impact of degree of stenosis, stenosis length, and residual lumen on intracranial blood flow in patients with extracranial carotid stenosis.

21 octubre 2014

STROKE. Clinical Sciences. Mechanisms of Unexplained Neurological Deterioration After Intravenous Thrombolysis

Marie Tisserand, MD*; Pierre Seners, MSc*; Guillaume Turc, MD; Laurence Legrand, MD; Marc-Antoine Labeyrie, MD; Sylvain Charron, PhD; Jean-François Méder, PhD; Jean-Louis Mas, MD; Catherine Oppenheim, PhD†; Jean-Claude Baron, ScD†

Background and Purpose: Unstable clinical course characterizes the first 24 hours after thrombolysis for anterior circulation stroke, including early neurological deterioration (END), a secondary complication consistently predictive of poor outcome. Apart from straightforward causes, such as intracerebral hemorrhage and malignant edema, the mechanism of END remains unclear in the majority of cases (ENDunexplained). Based on the core/penumbra model, we tested the hypothesis that ENDunexplained is caused by infarct growth beyond the initial penumbra and assessed the associated vascular patterns.

07 octubre 2014

STROKE. Clinical Sciences. Application of Single-Stage Stereotactic Radiosurgery for Cerebral Arteriovenous Malformations >10 cm3

Shunya Hanakita, MD; Tomoyuki Koga, MD, PhD; Masahiro Shin, MD, PhD; Hiroshi Igaki, MD, PhD; Nobuhito Saito, MD, PhD

Background and Purpose: Stereotactic radiosurgery (SRS) is a safe and effective treatment for small arteriovenous malformations (AVMs), the use of this modality for the treatment of large AVMs is still controversial, although it has been used in difficult cases. The aim of this study was to evaluate the treatment outcomes of patients who underwent single-stage SRS for large AVMs and to discuss the role of SRS in the treatment of these challenging lesions.

28 octubre 2014

STROKE. Clinical Sciences. Time to Angiographic Reperfusion in Acute Ischemic Stroke

Achala S. Vagal, MD, MS; Pooja Khatri, MD, MSc; Joseph P. Broderick, MD; Thomas A. Tomsick, MD; Sharon D. Yeatts, PhD; Mark H. Eckman, MD, MS

Background and Purpose: Our objective was to use decision analytic modeling to compare 2 treatment strategies of intravenous recombinant tissue-type plasminogen activator (r-tPA) alone versus combined intravenous r-tPA/endovascular therapy in a subgroup of patients with large vessel (internal carotid artery terminus, M1, and M2) occlusion based on varying times to angiographic reperfusion and varying rates of reperfusion.

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