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ABSTRACT


01 abril 2015

CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY. Carotid Stenting with Distal Protection in High-Surgical-Risk Patients: One-Year Results of the ASTI Trial

Marc Bosiers, Dierk Scheinert, Klaus Mathias, Ralf Langhoff, Harald Mudra, Juan Diaz-Cartelle

Purpose: This prospective, multicenter, nonrandomized study evaluated the periprocedural and 1-year outcomes in high-surgical-risk patients with carotid artery stenosis treated with the Adapt Carotid Stent plus FilterWire EZ distal protection catheter (Boston Scientific Corporation, Natick, MA).

01 abril 2015

CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY. Acute Stroke and Obstruction of the Extracranial Carotid Artery Combined with Intracranial Tandem Occlusion: Results of Interventional Revascularization

Stephanie Lescher, Katja Czeppan, Luciana Porto, Oliver C. Singer, Joachim Berkefeld

Purpose: Due to high thrombus load, acute stroke patients with tandem obstructions of the extra- and intracranial carotid arteries or the middle cerebral artery show a very limited response to systemic thrombolysis. Interventional treatment with mechanical thrombectomy—often in combination with acute stenting of underlying atherosclerotic stenosis or dissection—is increasingly used. It has been shown that such complex interventions are technically feasible. The lack of optimal management strategies and clinical data encouraged us to review our acute stroke interventions in patient with anterior circulation tandem lesions to determine lesion patterns, interventional approaches, and angiographic or clinical outcomes.

01 abril 2015

AMERICAN JOURNAL OF ROENTGENOLOGY. MRI and MR Angiography Findings to Differentiate Jugular Venous Reflux From Cavernous Dural Arteriovenous Fistula

Eunhee Kim, Jae Hyoung Kim, Byung Se Choi, Cheolkyu Jung and Dong Hoon Lee

OBJECTIVE. Both jugular venous reflux (JVR) and cavernous dural arteriovenous fistula (DAVF) manifest as abnormal venous signal intensities on time-of-flight (TOF) MR angiography (MRA). We investigated brain MRI and MRA findings that might differentiate JVR from cavernous DAVF.

14 agosto 2014

AMERICAN JOURNAL OF NEURORADIOLOGY. Surpass Flow Diverter in the Treatment of Intracranial Aneurysms: A Prospective Multicenter Study

A.K. Wakhloo, P. Lylyk, J. de Vries, C. Taschner, J. Lundquist, A. Biondi, M. Hartmann, I. Szikora, L. Pierot, N. Sakai, H. Imamura, N. Sourour, I. Rennie, M. Skalej, O. Beuing, A. Bonafé, F. Mery, F. Turjman, P. Brouwer, E. Boccardi, L. Valvassori, S. Derakhshani, M.W. Litzenberg, M.J. Gounis, for the Surpass Study Group

BACKGROUND AND PURPOSE: Incomplete occlusion and recanalization of large and wide-neck brain aneurysms treated by endovascular therapy remains a challenge. We present preliminary clinical and angiographic results of an experimentally optimized Surpass flow diverter for treatment of intracranial aneurysms in a prospective, multicenter, nonrandomized, single-arm study.

29 octubre 2014

AMERICAN JOURNAL OF NEURORADIOLOGY. International Retrospective Study of the Pipeline Embolization Device: A Multicenter Aneurysm Treatment Study

D.F. Kallmes, R. Hanel, D. Lopes, E. Boccardi, A. Bonafé, S. Cekirge, D. Fiorella, P. Jabbour, E. Levy, C. McDougall, A. Siddiqui, I. Szikora, H. Woo, F. Albuquerque, H. Bozorgchami, S.R. Dashti, J.E. Delgado Almandoz, M.E. Kelly, R. Turner IV, B.K. Woodward, W. Brinjikji, G. Lanzino and P. Lyly

BACKGROUND AND PURPOSE: Flow diverters are increasingly used in the endovascular treatment of intracranial aneurysms. Our aim was to determine neurologic complication rates following Pipeline Embolization Device placement for intracranial aneurysm treatment in a real-world setting.

24 julio 2014

AMERICAN JOURNAL OF NEURORADIOLOGY. Treatment of Poor-Grade Subarachnoid Hemorrhage Trial

D. Mitra, B. Gregson, V. Jayakrishnan, A. Gholkar, A. Vincent, P. White and P. Mitchell

BACKGROUND AND PURPOSE: Management of poor-grade subarachnoid hemorrhage is based on limited evidence from small single-center retrospective observational studies. The purpose of this study was to undertake a single-center randomized controlled feasibility trial comparing a strategy of early endovascular aneurysm treatment with treatment after neurologic recovery in this group of patients.

31 julio 2014

AMERICAN JOURNAL OF NEURORADIOLOGY. Rescue Treatment of Thromboembolic Complications during Endovascular Treatment of Cerebral Aneurysms: A Meta-Analysis

W. Brinjikji, S.F. Morales-Valero, M.H. Murad, H.J. Cloft and D.F. Kallmes

BACKGROUND AND PURPOSE: Intraprocedural thrombus formation during endovascular treatment of intracranial aneurysms is often treated with glycoprotein IIb/IIIa inhibitors and, in some instances, fibrinolytic therapy. We performed a meta-analysis evaluating the safety and efficacy of GP IIb/IIIa inhibitors compared with fibrinolysis. We also evaluated the safety and efficacy of abciximab, an irreversible inhibitor, compared with tirofiban and eptifibatide, reversible inhibitors of platelet function.

14 agosto 2014

AMERICAN JOURNAL OF NEURORADIOLOGY. One-Year MR Angiographic and Clinical Follow-Up after Intracranial Mechanical Thrombectomy Using a Stent Retriever Device

F. Eugène, J.-Y. Gauvrit, J.-C. Ferré, J.-C. Gentric, A. Besseghir, T. Ronzière and H. Raoult

BACKGROUND AND PURPOSE: Little is known about the consequences of arterial wall damage that may be due to mechanical endovascular thrombectomy. Our aim was to perform 1-year MR angiographic and clinical follow-up of patients treated with mechanical endovascular thrombectomy using the Solitaire device.

18 septiembre 2014

AMERICAN JOURNAL OF NEURORADIOLOGY. Parent Artery Curvature Influences Inflow Zone Location of Unruptured Sidewall Internal Carotid Artery Aneurysms

K. Futami, H. Sano, T. Kitabayashi, K. Misaki, M. Nakada, N. Uchiyama and F. Ueda

BACKGROUND AND PURPOSE: Future aneurysmal behaviors or treatment outcomes of cerebral aneurysms may be related to the hemodynamics around the inflow zone. Here we investigated the influence of parent artery curvature on the inflow zone location of unruptured sidewall internal carotid artery aneurysms.

22 octubre 2014

AMERICAN JOURNAL OF NEURORADIOLOGY. Visual Outcomes with Flow-Diverter Stents Covering the Ophthalmic Artery for Treatment of Internal Carotid Artery Aneurysms

A. Rouchaud, O. Leclerc, Y. Benayoun, S. Saleme, Y. Camilleri, F. D´Argento, M.-P. Boncoeur, P.-Y. Robert and C. Mounayer

BACKGROUND AND PURPOSE: Flow-diverting stents can be used to treat intracranial aneurysms that are not amenable to treatment with coils. We analyzed ophthalmic consequences due to coverage of the origin of the ophthalmic artery by flow-diverting stents for the treatment of internal carotid artery aneurysms.

16 octubre 2014

AMERICAN JOURNAL OF NEURORADIOLOGY. Efficacy of Skull Plain Films in Follow-up Evaluation of Cerebral Aneurysms Treated with Detachable Coils: Quantitative Assessment of Coil Mass

S.J. Ahn, B.M. Kim, W.S. Jung and S.H. Suh

BACKGROUND AND PURPOSE: Skull plain films of coiled aneurysms have been used in a limited role, including morphologic comparison of the coil mass. We aimed to evaluate the efficacy of skull plain films in patients treated with detachable coils by using quantitative assessment.

31 julio 2014

AMERICAN JOURNAL OF NEURORADIOLOGY. Parent Artery Occlusion in Large, Giant, or Fusiform Aneurysms of the Carotid Siphon: Clinical and Imaging Results

M.-A. Labeyrie, S. Lenck, D. Bresson, J.-P. Desilles, A. Bisdorff, J.-P. Saint-Maurice and E. Houdart

BACKGROUND AND PURPOSE: Parent artery occlusion has long been considered the reference treatment for large/giant or fusiform aneurysms of the carotid siphon. However, meager recent data exist on this technique, which tends to be replaced by stent-assisted reconstructive techniques. In our department since 2004, we have assessed the safety, efficacy, and complication risk factors of parent artery occlusion by using coils for trapping these aneurysms.

01 febrero 2015

JACC. Ischemic Brain Lesions After Carotid Artery Stenting Increase Future Cerebrovascular Risk

Henrik Gensicke, MD∗; H. Bart van der Worp, PhD†; Paul J. Nederkoorn, PhD‡; Sumaira Macdonald, PhD§; Peter A. Gaines, MBChB‖; Aad van der Lugt, MD¶; Willem P.Th.M. Mali, MD#; Philippe A. Lyrer, MD∗; Nils Peters, MD∗; Roland L. Featherstone, PhD∗∗; Gert J. de Borst, MD††; Stefan T. Engelter, MD∗; Martin M. Brown, MD∗∗; Leo H. Bonati, MD∗

Background: Brain lesions on diffusion-weighted imaging (DWI) are frequently found after carotid artery stenting (CAS), but their clinical relevance remains unclear.

08 diciembre 2014

CIRCULATION. Stroke. Strategy for Identifying Repurposed Drugs for the Treatment of Cerebral Cavernous Malformation

Christopher C. Gibson, PhD; Weiquan Zhu, PhD; Chadwick T. Davis, PhD; Jay A. Bowman-Kirigin, BS; Aubrey C. Chan, MD, PhD; Jing Ling, BA; Ashley E. Walker, PhD; Luca Goitre, PhD; Simona Delle Monache, PhD; Saverio Francesco Retta, PhD; Yan-Ting E. Shiu, PhD; Allie H. Grossmann, MD, PhD; Kirk R. Thomas, PhD; Anthony J. Donato, PhD; Lisa A. Lesniewski, PhD; Kevin J. Whitehead, MD; Dean Y. Li, MD, PhD

Background: Cerebral cavernous malformation (CCM) is a hemorrhagic stroke disease affecting up to 0.5% of North Americans that has no approved nonsurgical treatment. A subset of patients have a hereditary form of the disease due primarily to loss-of-function mutations in KRIT1, CCM2, or PDCD10. We sought to identify known drugs that could be repurposed to treat CCM.

12 octubre 2014

SPRINGER. Microembolic signal monitoring and the prediction of thromboembolic events following coil embolization of unruptured intracranial aneurysms: diffusion-weighted imaging correlation

Jae-Hoon Cho, Dong-Hun Kang, Yong-Won Kim, Jaechan Park, Yong-Sun Kim

Introduction: Microembolic signal (MES) monitoring with transcranial Doppler ultrasonography (TCD) may allow for early prediction of thromboembolisms following endovascular coiling of unruptured intracranial aneurysms (UIAs). However, the method has not gained widespread use and may benefit from correlation with diffusion-weighted imaging (DWI) of acute ischemic lesions after coiling. This purposed to evaluate the relationship between MESs and DWI-positive lesions more precisely.

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