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ABSTRACT


26 febrero 2015

AMERICAN JOURNAL OF NEURORADIOLOGY. The FRED Flow-Diverter Stent for Intracranial Aneurysms: Clinical Study to Assess Safety and Efficacy

M.A. Möhlenbruch, C. Herweh, L. Jestaedt, S. Stampfl, S. Schönenberger, P.A. Ringleb, M. Bendszus and M. Pham

BACKGROUND AND PURPOSE: Flow-diverter stents are emerging for the endovascular treatment of difficult-to-treat or otherwise untreatable cerebral aneurysms (wide-neck, fusiform, dissecting, blisterlike, or giant). We assessed the clinical safety and efficacy of the Flow-Redirection Endoluminal Device.

19 marzo 2015

AMERICAN JOURNAL OF NEURORADIOLOGY. Endovascular Treatment of Wide-Neck Anterior Communicating Artery Aneurysms Using WEB-DL and WEB-SL: Short-Term Results in a Multicenter Study

D.N. Gherasim, B. Gory, R. Sivan-Hoffmann, L. Pierot, H. Raoult, J.-Y. Gauvrit, H. Desal, X. Barreau, D. Herbreteau, R. Riva, F. Ambesi Impiombato, X. Armoiry and F. Turjman

BACKGROUND AND PURPOSE: Endovascular treatment of wide-neck anterior communicating artery aneurysms can often be challenging. The Woven EndoBridge (WEB) device is a recently developed intrasaccular flow disrupter dedicated to endovascular treatment of intracranial aneurysms. The aim of this study was to investigate the feasibility, safety, and efficacy of the WEB Dual-Layer and WEB Single-Layer devices for the treatment of wide-neck anterior communicating artery aneurysms.

12 marzo 2015

AMERICAN JOURNAL OF NEURORADIOLOGY. HydroCoils Reduce Recurrence Rates in Recently Ruptured Medium-Sized Intracranial Aneurysms: A Subgroup Analysis of the HELPS Trial

W. Brinjikji, P.M. White, H. Nahser, J. Wardlaw, R. Sellar, H.J. Cloft and D.F. Kallmes

BACKGROUND AND PURPOSE: The HydroCoil Endovascular Aneurysm Occlusion and Packing Study (HELPS) was a randomized, controlled trial comparing HydroCoils with bare-platinum coils. The purpose of this study was to perform a subgroup analysis of angiographic and clinical outcomes of medium-sized aneurysms in the HELPS trial.

01 julio 2015

NEUROSURGERY. Smoking and Intracranial Aneurysm Morphology

Ho, Allen L. MD*,‡; Lin, Ning MD§; Frerichs, Kai U. MD*,‡; Du, Rose MD, PhD*,‡

BACKGROUND: Smoking is a well-known independent risk factor for both aneurysm formation and rupture. There is mounting evidence that aneurysm morphology beyond size can have a significant role in aneurysm formation and rupture risk by its effects on aneurysmal hemodynamics.

01 septiembre 2015

NEUROSURGERY. Detachable-Tip Microcatheters for Liquid Embolization of Brain Arteriovenous Malformations and Fistulas: A United States Single-Center Experience

Herial, Nabeel A. MD*; Khan, Asif A. MD*; Sherr, Gregory T. MD‡; Qureshi, Mushtaq H. MD*; Suri, M. Fareed K. MD‡; Qureshi, Adnan I. MD*

BACKGROUND: The US Food and Drug Administration recently approved a detachable-tip microcatheter, the Apollo microcatheter (eV3, Inc, Irvine, California), to prevent catheter entrapment during embolization of brain arteriovenous malformations (AVMs) using liquid embolic systems.

01 septiembre 2015

NEUROSURGERY. Feasibility, Safety, and Periprocedural Complications of Pipeline Embolization for Intracranial Aneurysm Treatment Under Conscious Sedation: University at Buffalo Neurosurgery Experience

Rangel-Castilla, Leonardo MD*,‡; Cress, Marshall C. MD*,‡; Munich, Stephan A. MD*,‡; Sonig, Ashish MD, MS, MCh*,‡; Krishna, Chandan MD*,‡; Gu, Eugene Y. MD*,§; Snyder, Kenneth V. MD, PhD*,‡,§,¶,‖; Hopkins, L. Nelson MD*,‡,¶,‖,#; Siddiqui, Adnan H. MD, PhD*,‡,¶,‖,#; Levy, Elad I. MD, MBA*,‡,¶,‖

BACKGROUND: Endovascular Pipeline Embolization Device (PED) placement for intracranial aneurysms is performed under general anesthesia at most centers because of perceived improved image quality and patient safety.

01 septiembre 2015

NEUROSURGERY. Transarterial N-Butyl-2-cyanoacrylate Embolization of an Intraosseous Dural Arteriovenous Fistula Associated With Acute Epidural Hematoma: Technical Case Report

Yoshioka, Shotaro MD; Kuwayama, Kazuyuki MD, PhD; Satomi, Junichiro MD, PhD; Nagahiro, Shinji MD, PhD

BACKGROUND AND IMPORTANCE: Intraosseous dural arteriovenous fistulae (DAVF) are rare, especially those with drainage into the diploic venous system. The clinical presentation depends on the location of the lesion. This is the first report of an intraosseous DAVF associated with acute epidural hematoma.

01 septiembre 2015

NEUROSURGERY. Direct Repair of Iatrogenic Internal Carotid Artery Injury During Endoscopic Endonasal Approach Surgery With Temporary Endovascular Balloon-Assisted Occlusion: Technical Case Report

Cobb, Mary In-Ping Huang MD*; Nimjee, Shahid MD‡; Gonzalez, L. Fernando MD*; Jang, David Woojin MD§; Zomorodi, Ali MD*

BACKGROUND AND IMPORTANCE: Iatrogenic internal carotid artery (ICA) injuries during endoscopic endonasal approach (EEA) surgeries are associated with a high morbidity and mortality, with few acceptable methods described for repair.

01 septiembre 2015

NEUROSURGERY. Proposal of Venous Drainage–Based Classification System for Carotid Cavernous Fistulae With Validity Assessment in a Multicenter Cohort

Thomas, Ajith J. MD*; Chua, Michelle BS‡; Fusco, Matthew MD*; Ogilvy, Christopher S. MD*; Tubbs, R. Shane PhD§; Harrigan, Mark R. MD¶; Griessenauer, Christoph J. MD¶

BACKGROUND: Carotid cavernous fistulae (CCFs) are most commonly classified based on arterial supply. Symptomatology and treatment approach, however, are largely influenced by venous drainage.

01 septiembre 2015

NEUROSURGERY. Effect of Prior Embolization on Cerebral Arteriovenous Malformation Radiosurgery Outcomes: A Case-Control Study

Oermann, Eric K. MD*; Ding, Dale MD‡; Yen, Chun-Po MD‡; Starke, Robert M. MD, MSc‡; Bederson, Joshua B. MD*; Kondziolka, Douglas MD, MSc§; Sheehan, Jason P. MD, PhD‡

BACKGROUND: Embolization before stereotactic radiosurgery (SRS) for cerebral arteriovenous malformations (AVM) has been shown to negatively affect obliteration rates, but its impact on the risks of radiosurgery-induced complications and latency period hemorrhage is poorly defined.

01 septiembre 2015

NEUROSURGERY. Added Benefit of Stent Retriever Technology for Acute Ischemic Stroke: A Pooled Analysis of the NINDS tPA, SWIFT, and STAR Trials

Saposnik, Gustavo MD, MSc, FAHA*,‡; Lebovic, Gerald PhD§; Demchuk, Andrew MD, FAHA, FRCPC¶; Levy, Elad I. MD, MBA, FAHA‖; Ovbiagele, Bruce MD, MSc, FAHA#; Goyal, Mayank MD, FRCPC¶; Johnston, S. Claiborne MD, PhD, FAHA**

BACKGROUND: Endovascular treatment is increasingly being used in acute stroke care. However, although stent retrievers show improved flow restoration rates, their clinical benefits have been uncertain.

01 septiembre 2015

NEUROSURGERY. Intrinsic, Transitional, and Extrinsic Morphological Factors Associated With Rupture of Intracranial Aneurysms

Ho, Allen L. MD*,‡; Lin, Ning MD§; Frerichs, Kai U. MD*,‡; Du, Rose MD, PhD*,‡

BACKGROUND: As diagnosis and treatment of unruptured intracranial aneurysms continues to increase, management principles remain largely based on size. This is despite mounting evidence that aneurysm location and other morphologic variables could play a role in predicting overall risk of rupture. Morphological parameters can be divided into 3 main groups, those that are intrinsic to the aneurysm, those that are extrinsic to the aneurysm, and those that involve both the aneurysm and surrounding vasculature (transitional).

30 abril 2015

THE LANCET. Neurology. Safety and efficacy of desmoteplase given 3–9 h after ischaemic stroke in patients with occlusion or high-grade stenosis in major cerebral arteries (DIAS-3): a double-blind, randomised, placebo-controlled phase 3 trial

Prof Gregory W Albers, MD, Prof Rüdiger von Kummer, Dr med*, Thomas Truelsen, MD, Jens-Kristian S Jensen, MSc, Gabriela M Ravn, MSc, Bjørn A Grønning, MD, Prof Hugues Chabriat, MD, Ku-Chou Chang, MD, Prof Antonio E Davalos, MD, Prof Gary A Ford, FRCP, James Grotta, MD, Prof Markku Kaste, MD, Prof Lee H Schwamm, MD, Prof Ashfaq Shuaib, MD for the DIAS-3 Investigators†

Background: Current treatment of ischaemic stroke with thrombolytic therapy is restricted to 3–4·5 h after symptom onset. We aimed to assess the safety and efficacy of desmoteplase, a fibrin-dependent plasminogen activator, given between 3 h and 9 h after symptom onset in patients with occlusion or high-grade stenosis in major cerebral arteries.

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