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ABSTRACT


01 septiembre 2015

STROKE. Brief Report. Predictors of Good Outcome After Stent-Retriever Thrombectomy in Acute Basilar Artery Occlusion

Woong Yoon, MD; Seul Kee Kim, MD; Tae Wook Heo, MD; Byung Hyun Baek, MD; Yun Young Lee, MD; Heoung Keun Kang, MD

Background and Purpose: Factors related to prognosis after a modern mechanical thrombectomy in patients with acute basilar artery occlusion remain unclear. This study investigated the prognostic factors for patients with acute basilar artery occlusion who underwent a stent-retriever thrombectomy.

25 agosto 2015

STROKE. Clinical Sciences. Association of Intraplaque Hemorrhage and Acute Infarction in Patients With Basilar Artery Plaque

Jin Hee Yu, MD; Hyo Sung Kwak, MD, PhD; Gyung Ho Chung, MD, PhD; Seung Bae Hwang, MD; Mi Sung Park, MD, PhD; Seong Hoon Park, MD, PhD

Background and Purpose: High-resolution magnetic resonance imaging (HRMRI) is ideal for serial examination of diseased arterial walls because it is noninvasive and has superior capability of discriminating tissue characteristics. The aim of this study is to evaluate the prevalence and clinical relevance of intraplaque hemorrhage (IPH) in patients with basilar artery (BA) atherosclerosis using HRMRI.

18 agosto 2015

STROKE. Clinical Sciences. Thirty-Day Outcome of a Multicenter Registry Study of Stenting for Symptomatic Intracranial Artery Stenosis in China

Zhongrong Miao, MD; Yong Zhang, MD; Jie Shuai, MD; Changchun Jiang, MD; Qiyi Zhu, MD; Kangning Chen, MD; Li Liu, MD; Baomin Li, MD; Xiangqun Shi, MD; Lianbo Gao, MD; Yajie Liu, MD; Feng Wang, MD; Yongli Li, MD; Tieyan Liu, MD; Hongbo Zheng, MD; Yilong Wang, MD; Yongjun Wang, MD; the Study Group of Registry Study of Stenting for Symptomatic Intracranial Artery Stenosis in China

Background and Purpose: Although recent trials have suggested that stenting is worse than medical therapy for patients with severe symptomatic intracranial atherosclerotic stenosis, it is not clear whether this conclusion applies to a subset of patients with hypoperfusion symptoms. To justify for a new trial in China, we performed a multicenter prospective registry study to evaluate the safety and efficacy of endovascular stenting within 30 days for patients with severe symptomatic intracranial atherosclerotic stenosis.

01 octubre 2015

NEUROSURGERY. High-Risk Factors in Symptomatic Patients Undergoing Carotid Artery Stenting With Distal Protection: Buffalo Risk Assessment Scale (BRASS)

Fanous, Andrew A. MD*,‡; Natarajan, Sabareesh K. MD, MS*,‡; Jowdy, Patrick K. BS*,‡; Dumont, Travis M. MD*,‡,§; Mokin, Maxim MD, PhD*,‡,¶; Yu, Jihnhee PhD‖; Goldstein, Adam*,‡; Wach, Michael M. BS*,‡; Budny, James L. MD*,‡; Hopkins, L. Nelson MD*,‡,#,**,‡‡; Snyder, Kenneth V. MD, PhD*,‡,#,**,§§; Siddiqui, Adnan H. MD, PhD*,‡,#,**,‡‡; Levy, Elad I. MD, MBA*,‡,#,**

BACKGROUND: Demographics and vascular anatomy may play an important role in predicting periprocedural complications in symptomatic patients undergoing carotid artery stenting (CAS).

01 octubre 2015

NEUROSURGERY. Endovascular Therapy for Ruptured Cerebral Aneurysms in the Elderly: Poor Accessibility of the Guiding Catheter and Use of Local Anesthesia as the Predictors of Procedure-Related Rupture

Fukuda, Hitoshi MD*; Handa, Akira MD*; Koyanagi, Masaomi MD*; Yoshida, Kazumichi MD*; Lo, Benjamin W. Y. MD‡; Yamagata, Sen MD*

BACKGROUND: Endovascular therapy is favored for ruptured intracranial aneurysms in the elderly. However, poor accessibility to the aneurysm through the parent artery and use of local anesthesia in this age group may predispose to intraprocedural complications.

01 octubre 2015

NEUROSURGERY. Fate of the Ophthalmic Artery After Treatment With the Pipeline Embolization Device

Chalouhi, Nohra MD*; Daou, Badih MD*; Kung, David MD*; Zanaty, Mario MD*; Phillips, Jessica L. MD*; Tjoumakaris, Stavropoula MD*; Starke, Robert M. MD*; Hasan, David MD‡; Polifka, Adam MD*; Salas, Sussan MD*; Rosenwasser, Robert H. MD*; Jabbour, Pascal M. MD*

BACKGROUND: Flow diverters have emerged as a major tool in the treatment of cerebral aneurysms. A crucial issue with the use of flow diverters is the patency of side branches covered by the device, most importantly the ophthalmic artery (OA).

01 noviembre 2015

NEUROSURGERY. The Use of the Pipeline Embolization Device in the Management of Recurrent Previously Coiled Cerebral Aneurysms

Daou, Badih MD*; Starke, Robert M. MD*; Chalouhi, Nohra MD*; Tjoumakaris, Stavropoula MD*; Khoury, Jean MD*; Hasan, David MD‡; Rosenwasser, Robert H. MD*; Jabbour, Pascal M. MD*

BACKGROUND: The biggest downside of cerebral aneurysm coiling is the high rates of recurrence and retreatments. With the increasing number of aneurysm recurrences after failed coiling procedures, the best retreatment strategy remains unknown.

01 noviembre 2015

NEUROSURGERY. Effect of Carotid Revascularization Endarterectomy Versus Stenting Trial Results on the Performance of Carotid Artery Stent Placement and Carotid Endarterectomy in the United States

Siddiq, Farhan MD*; Adil, Malik M. MD*,‡; Malik, Ahmed A. MD*; Qureshi, Mushtaq H. MD*; Qureshi, Adnan I. MD*

BACKGROUND: CREST (Carotid Revascularization Endarterectomy Versus Stenting Trial) results, published in 2010, showed no difference in the rates of composite outcome (stroke, myocardial infarction, or death) between carotid artery stent placement (CAS) and carotid endarterectomy (CEA).

01 noviembre 2015

NEUROSURGERY. Cost Comparison of Surgical and Endovascular Treatment of Unruptured Giant Intracranial Aneurysms

Familiari, Pietro MD*,‡; Maldaner, Nicolai*,§; Kursumovic, Adisa MD¶; Rath, Stefan A. MD¶; Vajkoczy, Peter MD§; Raco, Antonino MD‡; Dengler, Julius MD§; on behalf of the Giant Intracranial Aneurysm Study Group

BACKGROUND: Giant intracranial aneurysms (GIAs), which are defined as intracranial aneurysms (IAs) with a diameter of ≥25 mm, are most likely associated with the highest treatment costs of all IAs. However, the treatment costs of unruptured GIAs have so far not been reported.

01 noviembre 2015

THE LANCET. Neurology. Safety, tolerability, and efficacy of TEV-48125 for preventive treatment of chronic migraine: a multicentre, randomised, double-blind, placebo-controlled, phase 2b study

Dr Marcelo E Bigal, MD, Prof Lars Edvinsson, MD, Alan M Rapoport, MD, Prof Richard B Lipton, MD, Egilius L H Spierings, MD, Prof Hans-Christoph Diener, MD, Rami Burstein, PhD, Pippa S Loupe, PhD, Yuju Ma, MS, Ronghua Yang, PhD, Prof Stephen D Silberstein, MD

Background: Benefits of calcitonin-gene related peptide (CGRP) inhibition have not been established in chronic migraine. Here we assess the safety, tolerability, and efficacy of two doses of TEV-48125, a monoclonal anti-CGRP antibody, in the preventive treatment of chronic migraine.

01 noviembre 2015

THE LANCET. Neurology. Safety, tolerability, and efficacy of TEV-48125 for preventive treatment of high-frequency episodic migraine: a multicentre, randomised, double-blind, placebo-controlled, phase 2b study

Dr Marcelo E Bigal, MD, David W Dodick, MD, Alan M Rapoport, MD, Prof Stephen D Silberstein, MD, Yuju Ma, MS, Ronghua Yang, PhD, Pippa S Loupe, PhD, Rami Burstein, PhD, Lawrence C Newman, MD, Prof Richard B Lipton, MD

Background: Calcitonin gene-related peptide (CGRP) is a validated target for the treatment of episodic migraine. Here we assess the safety, tolerability, and efficacy of TEV-48125, a monoclonal anti-CGRP antibody, in the preventive treatment of high-frequency episodic migraine.

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