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ABSTRACT


13 agosto 2015

AMERICAN JOURNAL OF NEURORADIOLOGY. Initial Experience with p64: A Novel Mechanically Detachable Flow Diverter for the Treatment of Intracranial Saccular Sidewall Aneurysms

S. Fischer, M. Aguilar-Pérez, E. Henkes, W. Kurre, O. Ganslandt, H. Bäzner and H. Henkes

BACKGROUND AND PURPOSE: Flow diverters are important tools for the treatment of intracranial aneurysms. We report a retrospective evaluation of the safety and efficacy of p64, a fully resheathable, detachable flow diverter, in the endovascular treatment of intracranial sidewall aneurysms.

07 agosto 2014

AHA/ASA Scientific Statement. Cervical Arterial Dissections and Association With Cervical Manipulative Therapy. A Statement for Healthcare Professionals From the American Heart Association/American Stroke Association

José Biller, MD, FAHA, Chair; Ralph L. Sacco, MS, MD, FAHA, Co-Chair; Felipe C. Albuquerque, MD; Bart M. Demaerschalk, MD, MSc; Pierre Fayad, MD, FAHA; Preston H. Long, DC, PhD; Lori D. Noorollah, MD; Peter D. Panagos, MD, FAHA; Wouter I. Schievink, MD; Neil E. Schwartz, MD, PhD; Ashfaq Shuaib, MD, FAHA; David E. Thaler, MD, PhD, FAHA; David L. Tirschwell, MD, MSc; on behalf of the American Heart Association Stroke Council

Purpose: Cervical artery dissections (CDs) are among the most common causes of stroke in young and middle-aged adults. The aim of this scientific statement is to review the current state of evidence on the diagnosis and management of CDs and their statistical association with cervical manipulative therapy (CMT). In some forms of CMT, a high or low amplitude thrust is applied to the cervical spine by a healthcare professional.

01 diciembre 2015

NEUROSURGERY. Resolution of Oculomotor Nerve Palsy Secondary to Posterior Communicating Artery Aneurysms: Comparison of Clipping and Coiling

McCracken, D. Jay MD*; Lovasik, Brendan P. BS‡; McCracken, Courtney E. PhD‡; Caplan, Justin M. MD§; Turan, Nefize MD*; Nogueira, Raul G. MD*; Cawley, C. Michael MD*; Dion, Jacques E. MD*; Tamargo, Rafael J. MD§; Barrow, Daniel L. MD*; Pradilla, Gustavo MD*

BACKGROUND: Previous studies have attempted to determine the best treatment for oculomotor nerve palsy (ONP) secondary to posterior communicating artery (PCoA) aneurysms, but have been limited by small sample sizes and limited treatment.

01 diciembre 2015

NEUROSURGERY. Contralateral Approach to Bilateral Middle Cerebral Artery Aneurysms: Comparative Study, Angiographic Analysis, and Surgical Results

Andrade-Barazarte, Hugo MD*,‡; Kivelev, Juri MD, PhD*; Goehre, Felix MD*,§; Jahromi, Behnam Rezai MB*; Noda, Kosumo MD¶; Ibrahim, Tarik F. MD*,‖; Kivisaari, Riku MD, PhD*; Lehto, Hanna MD, PhD*; Niemela, Mika MD, PhD*; Jääskeläinen, Juha E. MD, PhD#; Hernesniemi, Juha A. MD, PhD*

BACKGROUND: Bilateral aneurysms located between the 2 middle cerebral artery (MCA) bifurcations may be approachable through a single unilateral approach.

01 diciembre 2015

NEUROSURGERY. In-Pipeline Stenosis: Incidence, Predictors, and Clinical Outcomes

Chalouhi, Nohra MD*; Polifka, Adam MD*; Daou, Badih MD*; Kung, David MD*; Barros, Guilherme MD*; Tjoumakaris, Stavropula MD*; Gonzalez, L. Fernando MD*; Starke, Robert M. MD*; Hasan, David MD‡; Judy, Brendan MD*; Rosenwasser, Robert H. MD*; Jabbour, Pascal MD*

BACKGROUND: The Pipeline Embolization Device is a widely utilized flow diverter in the treatment of intracranial aneurysms.

01 enero 2016

NEUROSURGERY. P2Y12 Reaction Units: Effect on Hemorrhagic and Thromboembolic Complications in Patients With Cerebral Aneurysms Treated With the Pipeline Embolization Device

Daou, Badih MD; Starke, Robert M. MD; Chalouhi, Nohra MD; Barros, Guilherme MD; Tjoumakaris, Stavropoula MD; Rosenwasser, Robert H. MD; Jabbour, Pascal MD

BACKGROUND: The main concern with the use of the pipeline embolization device (PED) in treating cerebral aneurysms is the risk of hemorrhagic and thromboembolic complications.

01 enero 2016

NEUROSURGERY. Surgical Clipping of Very Small Unruptured Intracranial Aneurysms: A Multicenter International Study

Bruneau, Michaël MD, PhD*; Amin-Hanjani, Sepideh MD‡; Koroknay-Pal, Päivi MD, PhD§; Bijlenga, Philippe MD, PhD¶; Jahromi, Behnam Rezai MB§; Lehto, Hanna MD§; Kivisaari, Riku MD, PhD§; Schaller, Karl MD¶; Charbel, Fady MD‡; Khan, Sajeel MD‡; Mélot, Christian MD, PhD, MScBiostat‖; Niemela, Mika MD, PhD§; Hernesniemi, Juha MD, PhD§

BACKGROUND: Treatment of very small unruptured intracranial aneurysms (VSUIAs, defined as ≤3 mm) can be indicated in selected circumstances. The feasibility and outcomes of endovascular therapy for VSUIAs have been recently published; however, the efficacy and complication rate of surgical clipping has not been reported in any large series to date.

01 enero 2016

NEUROSURGERY. Clinical and Anatomical Follow-up in Patients With Aneurysms Treated With the WEB Device: 1-Year Follow-up Report in the Cumulated Population of 2 Prospective, Multicenter Series (WEBCAST and French Observatory)

Pierot, Laurent MD, PhD*; Spelle, Laurent MD, PhD‡; Molyneux, Andrew MD§; Byrne, James MD§; for the WEBCAST and French Observatory Investigators

BACKGROUND: Flow disruption with WEB is an innovative endovascular approach for wide-neck bifurcation aneurysms. Initial series have shown a low complication rate with good efficacy.

29 octubre 2015

STROKE. Brief Report. Prediction of Early Reperfusion From Repeated Arterial Spin Labeling Perfusion Magnetic Resonance Imaging During Intravenous Thrombolysis

Shuhei Okazaki, MD; Martin Griebe, MD; Johannes Gregori, PhD; Matthias Günther, PhD; Johannes Sauter-Servaes, MD; Marc E. Wolf, MD; Achim Gass, MD; Michael G. Hennerici, MD; Kristina Szabo, MD; Rolf Kern, MD

Background and Purpose: There are few in vivo data on the pathophysiology of reperfusion during systemic thrombolysis. We monitored the time course of cerebral perfusion changes in patients during thrombolysis with repeated arterial spin labeling perfusion magnetic resonance imaging.

10 noviembre 2015

STROKE. Brief Report. Estimating Weight of Patients With Acute Stroke When Dosing for Thrombolysis

Tom Barrow, BSc; Muhammad S. Khan, MSc; Omid Halse, MRCP; Paul Bentley, PhD; Pankaj Sharma, MD, PhD, FRCP

Background and Purpose: Estimating patient weight forms an important part of emergency ischemic stroke management guiding the dose of alteplase (tissue-type plasminogen activator). Weighing patients with stroke can be logistically challenging and time consuming, potentially delaying treatment times. We aimed to assess the reliability of approximating weight to determine recombinant tissue-type plasminogen activator dose and whether potential inaccurate dosing affected patient outcomes.

10 diciembre 2015

STROKE. Clinical Sciences. Impact of Glucose on Outcomes in Patients Treated With Mechanical Thrombectomy. A Post Hoc Analysis of the Solitaire Flow Restoration With the Intention for Thrombectomy Study

Joon-Tae Kim, MD; Reza Jahan, MD; Jeffrey L. Saver, MD, for the SWIFT Investigators

Background and Purpose: Sparse data are available regarding the association between hyperglycemia and outcomes in acute ischemic stroke patients receiving mechanical thrombectomy (MT). We investigated whether hyperglycemia affected the outcomes of subjects treated with MT in the Solitaire Flow Restoration With the Intention for Thrombectomy (SWIFT) multicenter randomized trial, overall and according to reperfusion status after MT.

24 noviembre 2015

STROKE. Clinical Sciences. Imaging Characteristics of Growing and Ruptured Vertebrobasilar Non-Saccular and Dolichoectatic Aneurysms

Deena M. Nasr, DO; Waleed Brinjikji, MD; Aymeric Rouchaud, MD; Ramanathan Kadirvel, PhD; Kelly D. Flemming, MD; David F. Kallmes, MD

Background and Purpose: Vertebrobasilar, nonsaccular, and dolichoectatic aneurysms generally have a poor natural history. We performed a study examining the natural history of vertebrobasilar, nonsaccular, and dolichoectatic aneurysms receiving serial imaging and studied imaging characteristics associated with growth and rupture.

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