29 marzo 2016

STROKE. Clinical Sciences. De Novo Aneurysm Formation in Carriers of Saccular Intracranial Aneurysm Disease in Eastern Finland

Antti E. Lindgren, MD, PhD*; Sari Räisänen, BM*; Joel Björkman, BM; Hanna Tattari, BM; Jukka Huttunen, MD; Terhi Huttunen, MD, PhD; Mitja I. Kurki, PhD; Juhana Frösen, MD, PhD; Timo Koivisto, MD, PhD; Juha E. Jääskeläinen, MD, PhD†; Mikael von und zu Fraunberg, MD, PhD†

Background and Purpose: Formation of new (de novo) aneurysms in patients carrying saccular intracranial aneurysm (sIA) disease has been published, but data from population-based cohorts are scarce.

07 abril 2016

STROKE. Clinical Sciences. Prevalence of Intracranial Atherosclerotic Stenosis Using High-Resolution Magnetic Resonance Angiography in the General Population. The Atherosclerosis Risk in Communities Study

Muhammad Fareed K. Suri, MD, MS*; Ye Qiao, PhD*; Xiaoye Ma, PhD; Eliseo Guallar, MD, DrPH; Jincheng Zhou, MS; Yiyi Zhang, PhD; Li Liu, MS; Haitao Chu, MD, PhD; Adnan I. Qureshi, MD; Alvaro Alonso, MD, PhD; Aaron R. Folsom, MD; Bruce A. Wasserman, MD

Background and Purpose: Intracranial atherosclerotic stenosis (ICAS) is a common cause of stroke, but little is known about its epidemiology. We studied the prevalence of ICAS and its association with vascular risk factors using high-resolution magnetic resonance angiography in a US cardiovascular cohort.

01 mayo 2016

NEUROSURGERY. Endovascular Management vs Intravenous Thrombolysis for Acute Stroke Secondary to Carotid Artery Dissection: Local Experience and Systematic Review

Haussen, Diogo C. MD; Jadhav, Ashutosh MD, PhD; Jovin, Tudor MD; Grossberg, Jonathan A. MD; Grigoryan, Mikayel MD; Nahab, Fadi MD; Obideen, Mahmoud MD; Lima, Andrey MD; Aghaebrahim, Amin MD; Gulati, Deepak MD; Nogueira, Raul G. MD

BACKGROUND: Little is known regarding the endovascular management of acute ischemic stroke (AIS) related to carotid artery dissection (CAD).

01 mayo 2016

NEUROSURGERY. Onyx Embolization for Isolated Type Dural Arteriovenous Fistula Using a Dual-Lumen Balloon Catheter

Kim, Jin Woo MD; Kim, Byung Moon MD; Park, Keun Young MD; Kim, Dong Joon MD; Kim, Dong Ik MD

BACKGROUND: Utilization of a dual-lumen balloon may improve Onyx penetration into isolated dural arteriovenous fistulas (i-DAVFs).

01 mayo 2016

NEUROSURGERY. A New Protocol for Anticoagulation With Tirofiban During Flow Diversion

Chalouhi, Nohra MD; Jabbour, Pascal MD; Daou, Badih MD; Starke, Robert M. MD; Shields, Bridget MD; Hasan, David M. MD

BACKGROUND: Flow diversion is increasingly used to treat intracranial aneurysms. In previous reports, patients were pretreated with aspirin and clopidogrel before the intervention for the prevention of thromboembolic complications.

01 mayo 2016

NEUROSURGERY. Outcomes of Multimodality Therapy in Pediatric Patients With Ruptured and Unruptured Brain Arteriovenous Malformations

Nerva, John D. MD; Kim, Louis J. MD; Barber, Jason MS; Rockhill, Jason K. MD, PhD; Hallam, Danial K. MD; Ghodke, Basavaraj V. MD; Sekhar, Laligam N. MD

BACKGROUND: Brain arteriovenous malformations (BAVMs) are a frequent cause of pediatric hemorrhagic stroke, which frequently results in significant morbidity and mortality.

01 abril 2016

NEUROSURGERY. Stereotactic Radiosurgery for Arteriovenous Malformations: The Effect of Treatment Period on Patient Outcomes

Pollock, Bruce E. MD; Link, Michael J. MD; Stafford, Scott L. MD; Garces, Yolanda I. MD; Foote, Robert L. MD

BACKGROUND: Stereotactic radiosurgery (SRS) has been performed on patients with cerebral arteriovenous malformations (AVMs) for over 40 years.

01 abril 2016

NEUROSURGERY. Association of Hemodynamic Factors With Intracranial Aneurysm Formation and Rupture: Systematic Review and Meta-analysis

Can, Anil MD; Du, Rose MD, PhD

BACKGROUND: Recent evidence suggests a link between the magnitude and distribution of hemodynamic factors and the formation and rupture of intracranial aneurysms. However, there are many conflicting results.

01 abril 2016

NEUROSURGERY. Recurrence of Cerebral Arteriovenous Malformations Following Resection in Adults: Does Preoperative Embolization Increase the Risk?

Ivanov, Alexander A. MD; Alaraj, Ali MD; Charbel, Fady T. MD; Aletich, Victor MD; Amin-Hanjani, Sepideh MD

BACKGROUND: Complete surgical resection of arteriovenous malformations (AVMs), documented by postoperative angiography, is generally felt to represent cure, obviating the need for long-term follow-up imaging. Although AVM recurrence has been reported in the pediatric population, this phenomenon has only rarely been documented in adults. Recurrence after treatment solely with embolization, however, has been reported more frequently. Thus, patients undergoing multimodal therapy with surgery following preoperative embolization may also be at higher risk for recurrence.

01 mayo 2016

NEUROSURGERY. Multisession Radiosurgery for Sellar and Parasellar Benign Meningiomas: Long-term Tumor Growth Control and Visual Outcome

Marchetti, Marcello MD; Bianchi, Stefania MD; Pinzi, Valentina MD; Tramacere, Irene PhD; Fumagalli, Maria Luisa PhD; Milanesi, Ida Maddalena MD; Ferroli, Paolo MD; Franzini, Angelo MD; Saini, Marco MD; DiMeco, Francesco MD; Fariselli, Laura MD

BACKGROUND: Concern about radiation-induced optic neuropathy (RION) has governed recent thinking about the role of radiation therapy in the treatment of meningiomas involving the anterior optic pathways. Despite this concern, during the last few years, the use of radiosurgery for such lesions has increased steadily.

01 mayo 2016

NEUROSURGERY. Lower Risk of Intracranial Arteriovenous Malformation Hemorrhage in Patients With Hereditary Hemorrhagic Telangiectasia

Yang, Wuyang MD; Liu, Ann BA; Hung, Alice L. BA; Braileanu, Maria MD; Wang, Joanna Y. BA; Caplan, Justin M. MD; Colby, Geoffrey P. MD, PhD; Coon, Alexander L. MD; Tamargo, Rafael J. MD; Ahn, Edward S. MD; Huang, Judy MD

BACKGROUND: Patients diagnosed with hereditary hemorrhagic telangiectasia (HHT) are at risk of developing intracranial arteriovenous malformations (AVM). However, the clinical manifestations and natural history of HHT-related AVMs remain unclear due to the rarity of these lesions.

23 abril 2016

THE LANCET. Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials

Prof Mayank Goyal, MD, Bijoy K Menon, MD, Wim H van Zwam, MD, Prof Diederik W J Dippel, MD, Prof Peter J Mitchell, MBBS, Prof Andrew M Demchuk, MD, Prof Antoni Dávalos, MD, Prof Charles B L M Majoie, MD, Prof Aad van der Lugt, MD, Maria A de Miquel, MD, Prof Geoffrey A Donnan, MD, Prof Yvo B W E M Roos, MD, Prof Alain Bonafe, MD, Reza Jahan, MD, Prof Hans-Christoph Diener, MD, Lucie A van den Berg, MD, Prof Elad I Levy, MD, Olvert A Berkhemer, MD, Vitor M Pereira, MD, Jeremy Rempel, MD, Mònica Millán, MD, Prof Stephen M Davis, MD, Prof Daniel Roy, MD, John Thornton, MD, Luis San Román, MD, Marc Ribó, MD, Debbie Beumer, MD, Prof Bruce Stouch, PhD, Scott Brown, PhD, Bruce C V Campbell, MD, Prof Robert J van Oostenbrugge, MD, Prof Jeffrey L Saver, MD, Prof Michael D Hill, MD, Dr Tudor G Jovin, MD for the HERMES collaborators

Background: In 2015, five randomised trials showed efficacy of endovascular thrombectomy over standard medical care in patients with acute ischaemic stroke caused by occlusion of arteries of the proximal anterior circulation. In this meta-analysis we, the trial investigators, aimed to pool individual patient data from these trials to address remaining questions about whether the therapy is efficacious across the diverse populations included.

26 marzo 2016

THE LANCET. Association between age and risk of stroke or death from carotid endarterectomy and carotid stenting: a meta-analysis of pooled patient data from four randomised trials

Prof George Howard, DrPH, Prof Gary S Roubin, MD, Prof Olav Jansen, MD, Prof Jeroen Hendrikse, MD, Prof Alison Halliday, MD, Prof Gustav Fraedrich, MD, Prof Hans-Henning Eckstein, MD, David Calvet, MD, Richard Bulbulia, MD, Leo H Bonati, MD, Prof Jean-Pierre Becquemin, MD, Prof Ale Algra, MD, Prof Martin M Brown, MD, Prof Peter A Ringleb, MD, Prof Thomas G Brott, MD, Prof Jean-Louis Mas, MD on behalf of the Carotid Stenting Trialists´ Collaboration

Background: Age was reported to be an effect-modifier in four randomised controlled trials comparing carotid artery stenting (CAS) and carotid endarterectomy (CEA), with better CEA outcomes than CAS outcomes noted in the more elderly patients. We aimed to describe the association of age with treatment differences in symptomatic patients and provide age-specific estimates of the risk of stroke and death within narrow (5 year) age groups.

01 marzo 2016

SPRINGER. Prediction of cerebral hyperperfusion syndrome after carotid artery stenting by CT perfusion imaging with acetazolamide challenge

Tomohide Yoshie , Toshihiro Ueda, Tatsuro Takada, Shinji Nogoshi, Takayuki Fukano, Yasuhiro Hasegawa

Introduction: Cerebral hyperperfusion syndrome (HPS) is an uncommon but serious complication of carotid artery stenting (CAS). The purpose of this study was to investigate the efficacy of CT perfusion imaging (CTP) with acetazolamide challenge to identify patients at risk for HPS after CAS.

01 marzo 2016

SPRINGER. Incidence of delayed ipsilateral intraparenchymal hemorrhage after stent-assisted coiling of intracranial aneurysms in a high-volume single center

Yasha Kayan, Josser E. Delgado Almandoz, Jennifer L. Fease, Kira Tran, Anna M. Milner, Jill M. Scholz

Introduction: Delayed ipsilateral intraparenchymal hemorrhage (IPH) has been reported following technically successful treatment of intracranial aneurysms using flow-diverting stents in up to 8.5 % of patients. We report a similar, though less frequent phenomenon in the setting of stent-assisted coil embolization.