National Institutes of Health researchers used the popular anti-wrinkle agent Botox to discover a new and important role for a group of molecules that nerve cells use to quickly send messages. This novel role for the molecules, called SNARES, may be a missing piece that scientists have been searching for to fully understand how brain cells communicate under normal and disease conditions.
For the first time, a small device implanted in the brain has accurately predicted the onset of seizures in some adults who have epilepsy that does not respond to drugs, according to a small proof-of-concept study published online first in The Lancet Neurology.
May 3, 2013—Using a large, multihospital database, investigators sought to evaluate the morbidity and mortality associated with the use of intra-arterial or intravenous thrombolytic agents or glycoprotein IIb/IIIa inhibitors (GPI) to treat acute intraprocedural thrombus formation during endovascular cerebral aneurysm treatment. Waleed Brinjikji, MD, et al recently published the findings online ahead of print in Stroke.
Los investigadores afirman que un estrés mental más elevado y unos ingresos más bajos podrían tener algo que ver
May 1, 2013—The American Association of Neurological Surgeons (AANS) announced results from a recent study conducted by investigators from Boston Children’s Hospital that showed that the urinary levels of hepatocyte growth factor (HGF) could serve as a biomarker capable of detecting the presence of arteriovenous malformations (AVMs). Edward Robert Smith, MD, presented data from the study at the AANS annual scientific meeting, which was held April 27 to May 1 in New Orleans, Louisiana. The presentation was titled Noninvasive Urinary Biomarkers Can Detect the Presence of Intracranial Arteriovenous Malformations.
May 1, 2013—Findings from an analysis of stent-assisted coiling of intracranial aneurysms in 508 patients at a single center were published by Nohra Chalouhi, MD, et al in Stroke (2013;44:1348–1353).
El consejero de sanidad, Javier Fernández Lasquetty, presentó, el pasado lunes, los primeros resultados de cinco de los 29 programas específicos orientados a personas mayores que el hospital de La Princesa está desarrollando, y que hasta el momento han beneficiado a cerca de 500 pacientes. Los 24 planes restantes también han comenzado, y están cada uno de ellos, en una fase diferente de desarrollo.
The current treatment preference for intracranial atherosclerotic disease is not intervention but medical management with neurosurgeons reluctant to request stenting by the interventionalist since the SAMMPRIS trial, according to a company release.
Stent-assisted coiling has evolved as an aneurysm treatment option for patients with large, side-wall or wide-neck aneurysms. Although stent-assisted coiling has been associated with lower angiographic recurrence rates than coiling alone for anatomically challenging aneurysms, high complications rates have been published. One study reported permanent neurological complications in 7.4% and procedure related mortality in 4.6% of patients, which was significantly higher than for those treated with coiling alone.(1) An editorial following this study commented on an “alarmingly high serious complication rate of stent-assisted coiling” in this cohort of largely unruptured aneurysms with a benign natural history.(2)
At the Carotid Challenge session, which took place at CX35 today in the main auditorium, 62% of delegates said that they believed flow diversion was a “game changer” after Andrew Platts, London, UK, spoke to them about the intervention for the anterior cerebral circulation.
In Leicester, UK, rapid-access surgery for symptomatic carotid stenosis has been offered since October 2008. Ross Naylor reviews the practical lessons that have been learned with the experience. He discussed this topic at CX35 on Tuesday.
En pacientes con fibrilación auricular (FA) "del mundo real", los resultados a largo plazo son superiores con dabigatrán (Pradaxa) que con warfarina, a pesar de tener la misma frecuencia de accidentes cerebrovasculares (ACV), embolias sistémicas y sangrados graves, revela un estudio realizado en Dinamarca tras la aprobación del fármaco.
The findings of study led by Jai J Shakar and published in Journal of NeuroInterventional Surgery indicated that the rupture of posterior communicating artery aneurysms, where clots obscure the aneurysm neck in the immediate post-coiling period (≤3days), is rare but has a 70% mortality rate.
Comer más alimentos ricos en fibra aparentemente reduce el riesgo de accidente cerebrovascular (ACV), según un nuevo estudio británico.
A stroke survivor s chances of living independently after 90 days are not improved by the use of devices inserted into the artery to dissolve or remove a stroke-causing clot shortly after the onset of symptoms, according to a randomized controlled trial involving 656 patients.
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