In a new study published online in the Journal of the American Heart Association, researchers at Columbia Engineering report that they have identified a new component of the biological mechanism that controls blood flow in the brain. Led by Elizabeth M C Hillman, associate professor of biomedical engineering, the team has demonstrated for the first time that the vascular endothelium plays a critical role in the regulation of blood flow in response to stimulation in the living brain.
Covidien has announced US Food and Drug Administration (FDA) approval of its Apollo Onyx delivery microcatheter—the first detachable tip micro catheter available in the USA. The new micro catheter is designed to mitigate the technical challenges of catheter retrieval during Onyx liquid embolic system embolisations of brain arteriovenous malformations.
Pulsar Vascular has announced that the US Food and Drug Administration (FDA) has approved an investigational device exemption (IDE) for the PulseRider. The IDE allows Pulsar Vascular to begin a multicentre clinical trial in support of a humanitarian device exemption (HDE) to evaluate the PulseRider for US approval for wide neck aneurysms at or near a bifurcation of the basilar tip or carotid terminus. There are currently no devices approved by the FDA for this indication.
Previously, experience with the Enterprise vascular reconstruction device (Codman) has only been described in studies as a bailout procedure after primary stenting for acute ischaemic stroke with the Wingspan stent delivery system (Boston Scientific).
Researchers at Mayo Clinic have demonstrated in a mouse model that their recently developed synthetic peptide carrier is a potential delivery vehicle for brain cancer chemotherapy drugs and other neurological medications. The findings appear in PLOS ONE.
InspireMD has announced that it has concluded enrolment in its CARENET (Carotid embolic protection study using MicroNet) clinical trial. The multi-specialty trial is assessing the peri-procedural safety and efficacy of CGuard systems in the treatment of carotid lesions. The acute procedural performance of the CGuard device was 100% successful for all of the 30 patients enrolled in the trial.
The Apollo system, manufactured by Penumbra, has been widely launched following first-in-man clinical use at leading US hospitals.
A combined approach with the Penumbra aspiration system (Penumbra) and the Solitaire FR retrieval device (ev3, Covidien) has been successfully used in a patient with extensive superior sagittal sinus thrombosis and cortical venous thrombosis, according to a case report.
A new national centre of excellence for the treatment of epilepsy in Scotland, which integrates health care with social care, has recorded a 100% success rate in its first year.
New evidence shows that the omega-3 polyunsaturated fatty acids (PUFAs) found in seafood and marine oils, DHA and EPA, can significantly reduce damage from stroke in a mouse model when given immediately afterwards. Moreover, DHA and another PUFA demonstrate a positive effect on neurocognitive function in children. These findings and more were presented 29-30 June at the 11thCongress of the International Society for the Study of Fatty Acids and Lipids (ISSFAL) in Stockholm, Sweden.
The American Heart Association is funding a new research network to help people make behaviour changes to prevent heart disease and stroke, the two leading causes of death in the world.
Covidien announced the European launch of its Pipeline Flex embolisation device at the annual Live Interventional Neuroradiology and Neurosurgery Course (LINNC, 23–25 June, Paris, France). This next-generation flow diversion device received CE mark earlier this year.
Royal Philips has announced the introduction of NeuroSuite, a new integrated solution designed to support and enhance minimally invasive image-guided neurological interventions. Philips’ new interventional X-ray solution offers more effective device guidance and placement in every neuroradiology procedure.
Airo Mobile Intraoperative CT, developed and manufactured by Mobius Imaging and distributed by Brainlab, was awarded gold in the Radiological and Electromechanical Device category of the 17th Annual Medical Design Excellence Awards (MDEA) competition. Award winners were announced on June 11, 2014 at MD&M East’s main networking event—the 2014 Medical Design Excellence Awards ceremony held in New York. This distinction comes just months after Airo was honoured with a 2014 Red Dot Product Design Award.
Researchers at the Allen Institute for Brain Science have mapped the development of the mouse brain from the embryo to the adult, creating a preliminary genetic key that allows them to pinpoint the age and location of regions of the developing brain. This work lays the foundation for tracking regions of the mouse brain through development, which could have valuable implications for translational work in human brain developmental disorders. The research, profiling the publicly available Allen Developing Mouse Brain Atlas, is published in the journal Neuron.
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