Published in the online edition of the Journal of Biological Chemistry, the results of the extensive studies offer a new target for drug development in the quest for a cure for Alzheimer’s, the most prevalent form of dementia in the elderly.
Preliminary results of an open-label trial carried in the Journal of Headache and Pain reported that a single treatment with electroCore’s handheld non-invasive vagus nerve stimulation device gammaCore, completely resolved 44.8% of migraines within 30 minutes, with an additional 11.4% experiencing moderate benefits (incomplete resolution of their headaches) by two hours.
Future prevention and treatment strategies for vascular diseases may lie in the evaluation of early brain imaging tests long before heart attacks or strokes occur, according to a systematic review conducted by a team of cardiologists, neuroscientists, and psychiatrists from Icahn School of Medicine at Mount Sinai and published in JACC Cardiovascular Imaging.
People with multiple sclerosis should be offered a rapid and accurate diagnosis of their condition and access to specialist advice and proven therapies, says the National Institute for Healthcare and Excellence (NICE).
Costs to treat strokes caused by bleeding in the brain may increase significantly 10 years later, according to a study in the American Heart Association journal Stroke. The Australian study is the first to include 10 years of follow-up data on stroke cost estimates.
Using stents to keep neck arteries open is just as effective as invasive neck surgery for long-term prevention of fatal and disabling strokes, reports an international trial led by University College London funded by the Medical Research Council and Stroke Association.
Restenosis, the recurrence of narrowing of the arteries after stenting, is a common risk of this endovascular treatment. There are no well-defined guidelines to treat restenosis, but recent studies have shown excellent results with drug-eluting balloon angioplasty in coronary and femoral artery stents. However, few studies have focused on the carotid arteries, which take blood to the neck and head.
InVivo Therapeutics has announced that the first subject has been enrolled in the pilot study of its Neuro-Spinal Scaffold for the treatment of complete traumatic spinal cord injury at the Barrow Neurological Institute at St Joseph’s Hospital and Medical Center in Phoenix, USA. The objective of the pilot study is to evaluate the safety and feasibility of the Neuro-Spinal Scaffold as well as to gather preliminary evidence of effectiveness.
November 6, 2014—Lazarus Effect, Inc. announced that the company’s Lazarus Cover accessory device has received European CE Mark approval. The device is a nitinol mesh cover that surrounds a retriever device and captured material during removal from a blood vessel. Lazarus Effect plans to launch the Lazarus Cover in Europe during the first quarter of 2015.
November 4, 2014—VIVA Physicians, Inc. announced that Christopher J. Kwolek, MD, presented findings from the ROADSTER pivotal trial during a late-breaking trials session at the VIVA 2014: Vascular InterVentional Advances meeting in Las Vegas, Nevada. ROADSTER is a prospective, multicenter, investigational device exemption study designed to evaluate the safety and effectiveness of a novel hybrid carotid revascularization procedure using Silk Road Medical, Inc.’s Enroute transcarotid neuroprotection system (NPS).
November 4, 2014—VIVA Physicians, Inc. announced that D. Christopher Metzger, MD, presented findings from the CANOPY trial during a late-breaking trials session at the VIVA 2014: Vascular InterVentional Advances meeting in Las Vegas, Nevada. CANOPY is a prospective, multicenter, nonrandomized, single-arm, postapproval study to evaluate the safety and effectiveness of the RX Acculink carotid stent system (Abbott Vascular) in patients at standard risk for adverse events from carotid endarterectomy (CEA). CANOPY was mandated by the US Food and Drug Administration as a follow-up study to the CREST trial.
InspireMD has announced positive results from the CARENET (Carotid embolic protection study using microNET) trial for its CGuard embolic protection system. This trial demonstrates that the MicroNet covered CGuard may offer important clinical benefits for patients undergoing carotid artery stenting.
Medtronic has announced the launch of the Kyphon Express II Balloon Kyphoplasty Platform, which includes the next generation Kyphon Cement Delivery System. This new platform is the latest advancement in the Kyphon Balloon Kyphoplasty technology for the treatment of vertebral compression fractures.
New data presented at the Society of NeuroInterventional Surgery (SNIS) 11th Annual Meeting in (28 –31, Colorado Springs, USA) helps prove that written care protocols can significantly improve the overall emergency care pathway for stroke.
Codman Neuro, part of DePuy Synthes Companies of Johnson & Johnson, has announced the launch of the Envoy DA XB distal access guiding catheter and the 7F Envoy guiding catheter for neurovascular procedures
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