BACKGROUND AND PURPOSE: Recent studies highlight the role of CC in preserving ischemic penumbra. Some authors suggested the quality of CC could also impact recanalization. The purpose of this study is to test this hypothesis in patients who were treated with IV thrombolysis for MCA-M1 occlusion.
Background and Purpose— The introduction of flow diverters (FDs) has expanded the possibilities for reconstructive treatment of difficult intracranial aneurysms. Concern remains as to the long-term patency of the perforating arteries and side branches covered during stent placement. Our purpose was to evaluate the performance of and early effect on covered branches after implantation of the Silk FD in the treatment of basilar artery aneurysms.
BACKGROUND AND PURPOSE: Flow-diverter stents modify intra-aneurysmal blood flow and induce the progressive thrombosis of intracranial aneurysms followed by stable vascular reconstruction. The aim of this study was to report a new method for the appraisal of intracranial blood flow from DSA performed during endovascular treatment procedures. Published online before print November 1, 2012, doi: 10.3174/ajnr.A3322 AJNR 2012 . Copyright © 2012 by American Society of Neuroradiology.
Introduction: The aim of this study was to analyze the clinical features and early and late outcome of patients treated with carotid artery stenting for carotid stenosis with occlusion of the contralateral vessel (CAS-CCO), and compare them to patients without occlusion (CAS-NO). NeuroradiologyA Journal Devoted to Neuroimaging and Interventional Neuroradiology. Copyright © Springer-Verlag 201110.1007/s00234-011-0974-8
BACKGROUND AND PURPOSE: Effects of blood flow modification by flow diverters are observed to lead often to aneurysm thrombosis and reverse remodeling. For this process, to further understand the potential roles of intra-aneurysmal blood pressure changes and aneurysm morphologies, 23 patients were studied by numeric simulation. Published online before print September 27, 2012, doi: 10.3174/ajnr.A3288 AJNR 2012. Copyright © 2012 by American Society of Neuroradiology.
Introduction: The possibility of recanalization and the need for retreatment are the most important limitations of intracranial aneurysm embolization. The purpose of the study was to compare the size of aneurysm remnants measured at follow-up with three-dimensional digital subtracted angiography (3D-DSA) and magnetic resonance angiography (MRA). Neuroradiology December 2012, Volume 54, Issue 12, pp 1381-1388. Copyright © The Author(s) 2012. This article is published with open access at Springerlink.com
SUMMARY: As stroke is one of the leading causes of death and long-term morbidity worldwide, the research community has studied cardiac embolic sources, as well as vessel wall pathologies. For the latter, attention has been focused on defining morphologic tissue features associated with catastrophic events stemming from the carotid artery. Multiple noninvasive imaging modalities are currently being used to image and classify carotid atherosclerotic plaques, such as MR imaging, CT, and sonography, in an effort to provide clinically relevant predictive metrics for use in patient risk stratification and to define appropriate treatment options. This article compares and contrasts these existing clinical imaging modalities along with discussion of a new endovascular technique originally developed for cardiology, OCT, with which 3D comprehensive high-resolution images of the arterial wall can be acquired. Published online before print March 8, 2012, doi: 10.3174/ajnr.A2753 AJNR 2012 33: 1642-1650. Copyright © 2012 by American Journal of Neuroradiology
Background and Purpose—Rupture of atherosclerotic plaques is one of the main causes of ischemic strokes. The aim of this study was to investigate carotid plaque vulnerability markers in relation to blood flow direction and the mechanisms leading to plaque rupture at the upstream side of carotid stenoses. Stroke. 2011; 42: 3502-3510 Published online before print October 13, 2011, doi: 10.1161/STROKEAHA.111.627265. Copyright © 2011 American Heart Association, Inc. All rights reserved.
Background and Purpose—High stroke event rates among carotid artery stenting (CAS)-treated patients in the Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST) lead-in registry generated an a priori hypothesis that age may modify the relative efficacy of CAS versus carotid endarterectomy (CEA). In the primary CREST report, we previously noted significant effect modification by age. Here we extend this investigation by examining the relative efficacy of the components of the primary end point, the treatment-specific impact of age, and contributors to the increasing risk in CAS-treated patients at older ages. Stroke. 2011; 42: 3484-3490 Published online before print October 6, 2011, doi: 10.1161/STROKEAHA.111.624155. Copyright © 2011 American Heart Association, Inc. All rights reserved.
Introduction: The most significant factors leading to restenosis are yet to be described in the literature. The purpose of our study was to identify the incidence of restenosis in our patients with carotid artery stenting (CAS) for carotid atherosclerotic disease and to identify risk factors that are significantly responsible or related to the restenosis. Neuroradiology December 2012, Volume 54, Issue 12, pp 1347-1353. Copyright © The Author(s) 2012. This article is published with open access at Springerlink.com
SUMMARY: In contrast to cervical and lumbar fusion procedures, the principal aim of disk arthroplasty is to recapitulate the normal kinematics and biomechanics of the spinal segment affected. Following decompression of the neural elements, disk arthroplasty allows restoration of disk height and maintenance of spinal alignment. Based on clinical observations and biomechanical testing, the anticipated advantage of arthroplasty over standard arthrodesis techniques has been a proposed reduction in the development of symptomatic ALD. In this review of cervical and lumbar disk arthroplasty, we highlight the clinical results and experience with standard fusion techniques, incidence of ALD in the population of patients with surgical fusion, and indications for arthroplasty, as well as the biomechanical and clinical outcomes following arthroplasty. In addition, we introduce the devices currently available and provide a critical appraisal of the clinical evidence regarding arthroplasty procedures. Published online before print October 27, 2011, doi: 10.3174/ajnr.A2758 AJNR 2012 33: 1631-1641. Copyright © 2012 by American Journal of Neuroradiology
Based on current data and experience, the joint working group of the European Society of Minimally Invasive Neurological Therapy (ESMINT) and the European Society of Neuroradiology (ESNR) make suggestions on trial design and conduct aimed to investigate therapeutic effects of mechanical thrombectomy (MT). We anticipate that this roadmap will facilitate the setting up and conduct of successful trials in close collaboration with our neighbouring disciplines. NeuroradiologyA Journal Devoted to Neuroimaging and Interventional Neuroradiology. Copyright © Springer-Verlag 201210.1007/s00234-012-1076-y
A new era of stroke treatment may have begun with mechanical thrombectomy (MT) by fully deployed closed-cell self-expanding stents (stent-triever). Multiple case series and the first randomised controlled trials (RCTs) have now been published. More studies are under way involving large numbers of patients, which in turn has resulted in less strict “pragmatic” study protocols. Problems with current trials include a lack of standardisation in the conduct of the recanalisation procedure, the definition of primary endpoints such as the grade of arterial recanalisation and tissue reperfusion, and the post-surgical care provided. In Part 1 of this two part series, we outline the current situation and the major research questions. NeuroradiologyA Journal Devoted to Neuroimaging and Interventional Neuroradiology. Copyright © Springer-Verlag 201210.1007/s00234-012-1075-z
Background and Purpose—Arterial hypotension is more frequently observed early after carotid artery stenting (CAS) than after carotid endarterectomy (CEA), but their long-term effects on blood pressure (BP) are unclear. We compared the effects of CAS and CEA on BP up to 1 year after treatment in the International Carotid Stenting Study. Stroke. 2011; 42: 3491-3496 Published online before print October 13, 2011, doi: 10.1161/STROKEAHA.111.624478. Copyright © 2011 American Heart Association, Inc. All rights reserved.
Background and Purpose—Limited data are available concerning the outcome of angioplasty/stenting for subacute atherosclerotic intracranial artery occlusion, which is often associated with progressive symptom development in the salvageable brain under ischemic threat due to poor collateral blood supply. Stroke. 2011; 42: 3470-3476 Published online before print September 22, 2011, doi: 10.1161/STROKEAHA.111.622282. Copyright © 2011 American Heart Association, Inc. All rights reserved.
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