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ESTUDIOS


Hemorrhagic Transformation After Thrombectomy for Tandem Occlusions

François Zhu, Julien Labreuche, Diogo C. Haussen, Michel Piotin, Henrik Steglich-Arnholm, Christian Taschner, Panagiotis Papanagiotou, Bertrand Lapergue, Franziska Dorn, Christophe Cognard, Monika Killer, Marios N. Psychogios, Alejandro Spiotta, Mikael Mazighi, Serge Bracard, Francis Turjman, Sébastien Richard, Benjamin Gory and the TITAN (Thrombectomy in Tandem Lesions) Investigators

Background and Purpose— Carotid artery stenting in tandem large vessel occlusion strokes is usually avoided because of the intracranial hemorrhagic risks induced by antiplatelet therapy during thrombectomy interventions. This study aimed to evaluate the incidence of hemorrhagic transformation following thrombectomy in large vessel occlusion strokes patients with atherosclerotic cervical carotid occlusion, associated factors, and clinical relevance.

Predictive Value of Susceptibility Vessel Sign for Arterial Recanalization and Clinical Improvement in Ischemic Stroke

Jean Darcourt, Pattarawit Withayasuk, Ivan Vukasinovic, Caterina Michelozzi, Guillaume Bellanger, Adrien Guenego, Gilles Adam, Margaux Roques, Anne Christine Januel, Philippe Tall, Olivier Meyrignac, Vanessa Rousseau, Cédric Garcia, Jean François Albucher, Bernard Payrastre, Fabrice Bonneville, Jean Marc Olivot and Christophe Cognard

Background and Purpose— Our goal was to evaluate whether the presence of a low signal intensity known as susceptibility vessel sign (SVS) on T2*-gradient echo imaging sequence was predictive of arterial recanalization and the early clinical improvement after mechanical thrombectomy.

Impact of Stent Retriever Size on Clinical and Angiographic Outcomes in the STRATIS Stroke Thrombectomy Registry

Osama O. Zaidat, Diogo C. Haussen, Ameer E. Hassan, Ashutosh P. Jadhav, Brijesh P. Mehta, Maxim Mokin, Nils H. Mueller-Kronast and Michael T. Froehler

Background and Purpose— The safety and efficacy of mechanical thrombectomy in patients with acute ischemic stroke has been demonstrated. However, the impact of stent retriever size on clinical and angiographic outcomes is not well established.

Emergent Management of Tandem Lesions in Acute Ischemic Stroke

Ashutosh P. Jadhav, Osama O. Zaidat, David S. Liebeskind, Dileep R. Yavagal, Diogo C. Haussen, Frank R. Hellinger Jr, Reza Jahan, Mouhammad A. Jumaa, Viktor Szeder, Raul G. Nogueira and Tudor G. Jovin

Background and Purpose— Although intracranial thrombectomy represents the standard treatment approach for anterior circulation tandem occlusions, whether the extracranial lesion requires acute stenting remains unclear. Our aim was to investigate differences in clinical and procedural outcomes related to stenting extracranial lesions in a registry of patients undergoing thrombectomy for acute stroke.

Endovascular Treatment

Kars C.J. Compagne, Pieter M. van der Sluijs, Ido R. van den Wijngaard, Bob Roozenbeek, Maxim J.H.L. Mulder, Wim H. van Zwam, Bart J. Emmer, Charles B.L.M. Majoie, Albert J. Yoo, Geert J. Lycklama à Nijeholt, Hester F. Lingsma, Diederik W.J. Dippel, Aad van der Lugt and Adriaan C.G.M. van Es

Background and Purpose— It is unclear whether endovascular treatment (EVT) is beneficial for patients with acute ischemic stroke with occlusion of the M2 segment of the middle cerebral artery. We aimed to compare functional outcomes, technical aspects, and complications of EVT between patients with acute ischemic stroke because of M2 and M1 occlusions in clinical practice. Furthermore, outcome and complications after EVT in dominant and nondominant caliber M2 division occlusions were studied.

Safety of Carotid Revascularization in Patients With a History of Coronary Heart Disease

Eline J. Volkers, Ale Algra, L. Jaap Kappelle, Jean-Pierre Becquemin, Gert J. de Borst, Martin M. Brown, Richard Bulbulia, David Calvet, Hans-Henning Eckstein, Gustav Fraedrich, John Gregson, Alison Halliday, Jeroen Hendrikse, George Howard, Olav Jansen, Gary S. Roubin, Leo H. Bonati, Thomas G. Brott, Jean-Louis Mas, Peter A. Ringleb, Jacoba P. Greving and on behalf of the Carotid Stenosis Trialists’ Collaboration

Background and Purpose— We investigated whether procedural stroke or death risk of carotid artery stenting (CAS) compared with carotid endarterectomy (CEA) is different in patients with and without history of coronary heart disease (CHD) and whether the treatment-specific impact of age differs.

Vertebral Artery Patency and Thrombectomy in Basilar Artery Occlusions

Tobias Boeckh-Behrens, David Pree, Nina Lummel, Benjamin Friedrich, Christian Maegerlein, Kornelia Kreiser, Jan Kirschke, Maria Berndt, Manuel Lehm, Silke Wunderlich, Pascal J. Mosimann, Urs Fischer, Claus Zimmer and Johannes Kaesmacher

Background and Purpose— Factors influencing recanalization success in basilar artery occlusions are largely unknown. Preliminary evidence has suggested that flow arrest in the vertebral artery contralateral to the catheter bearing vertebral artery may facilitate recanalization. The aim of this analysis was to assess the impact of anatomic variations and flow conditions on recanalization success in basilar artery occlusion treated with mechanical thrombectomy.

Magnetic Resonance Imaging Versus Computed Tomography Angiography Based Selection for Endovascular Therapy in Patients With Acute Ischemic Stroke

Joon-Tae Kim, Bang-Hoon Cho, Kang-Ho Choi, Man-Seok Park, Beom Joon Kim, Jong-Moo Park, Kyusik Kang, Soo Joo Lee, Jae Guk Kim, Jae-Kwan Cha, Dae-Hyun Kim, Hyun-Wook Nah, Tai Hwan Park, Sang-Soon Park, Kyung Bok Lee, Jun Lee, Keun-Sik Hong, Yong-Jin Cho, Hong-Kyun Park, Byung-Chul Lee, Kyung-Ho Yu, Mi Sun Oh, Dong-Eog Kim, Wi-Sun Ryu, Jay Chol Choi, Jee-Hyun Kwon, Wook-Joo Kim, Dong-Ick Shin, Min-Ju Yeo, Sung Il Sohn, Jeong-Ho Hong, Ji Sung Lee, Juneyoung Lee, Hee-Joon Bae and Ki-Hyun Cho

Background and Purpose— Randomized trials comparing the use of multimodal magnetic resonance imaging (MRI) to multimodal computed tomography (CT)/ CT angiography (CTA) for selecting candidates for endovascular therapy (EVT) have not been reported. This study aimed to elucidate whether MRI-based selection for EVT is safe and effective within and after a 6-hour time window compared with conventional CTA-based selection.

Intraluminal Thrombi in the Cervico-Cephalic Arteries

Ravinder-Jeet Singh, Debabrata Chakraborty, Sadanand Dey, Aravind Ganesh, Abdulaziz Sulaiman Al Sultan, Muneer Eesa, John H. Wong, Mayank Goyal, Michael D. Hill and Bijoy K. Menon

Background and Purpose— Intraluminal thrombus (ILT) is an uncommon finding among patients with ischemic stroke. We report clinical-imaging manifestations, treatment offered, and outcome among patients with ischemic stroke/transient ischemic attack and ILT in their cervico-cephalic arteries.

Cortical Cerebral Microinfarcts on 3T Magnetic Resonance Imaging in Patients With Carotid Artery Stenosis

Junji Takasugi, Kaori Miwa, Yoshiyuki Watanabe, Shuhei Okazaki, Kenichi Todo, Tsutomu Sasaki, Manabu Sakaguchi and Hideki Mochizuki

Background and Purpose— Carotid artery stenosis is common in the elderly and contributes to cognitive impairment and dementia. Cortical cerebral microinfarcts (CMIs) play an important role in vascular cognitive impairment and dementia. We aimed to investigate the association between CMIs on 3T magnetic resonance imaging and clinical and radiological features, including plaque morphology, and cognitive function in patients with carotid stenosis.

14 febrero 2019

Rapid Alteplase Administration Improves Functional Outcomes in Patients With Stroke due to Large Vessel Occlusions

Mayank Goyal, Mohammed Almekhlafi, Diederik W. Dippel, Bruce C.V. Campbell, Keith Muir, Andrew M. Demchuk, Serge Bracard, Antoni Davalos, Francis Guillemin, Tudor G. Jovin, Bijoy K. Menon, Peter J. Mitchell, Scott Brown, Philip White, Charles B.L.M. Majoie, Jeffrey L. Saver, Michael D. Hill and for the HERMES Collaborators

Background and Purpose— We report the relation of onset-to-treatment time and door-to-needle time with functional outcomes and mortality among patients with ischemic stroke with imaging-proven large vessel occlusion treated with intravenous alteplase

Clinical Effects of Early Edaravone Use in Acute Ischemic Stroke Patients Treated by Endovascular Reperfusion Therapy

Masaya Enomoto, Akira Endo, Hiroshi Yatsushige, Kiyohide Fushimi and Yasuhiro Otomo

Background and Purpose— Although several clinical studies suggested the beneficial effects of edaravone in acute ischemic stroke, most were performed under settings that differ from those in the current treatment strategy, which has dramatically changed with progress in reperfusion therapies. This study aimed to evaluate the efficacy of edaravone in patients with acute ischemic stroke treated by emergent endovascular reperfusion therapy.

Effect of Workflow Improvements in Endovascular Stroke Treatment

Paula M. Janssen, Esmee Venema and Diederik W.J. Dippel

Background and Purpose— Rapid initiation of endovascular stroke treatment is associated with better clinical outcome. The effect of specific improvements is not well known. We performed a systematic review and meta-analysis on the effectiveness of specific workflow improvements on time to treatment and outcome.

STROKE. Anatomical Venous Variants in Children With Cerebral Sinovenous Thrombosis

Elizabeth Kouzmitcheva , Andrea Andrade , Prakash Muthusami , Manohar Shroff , Daune L. MacGregor , Gabrielle deVeber , Nomazulu Dlamini and Mahendranath Moharir

Background and Purpose Literature is sparse on the frequency and significance of anatomical venous variants (AVVs) in pediatric cerebral sinovenous thrombosis (CSVT)

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