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ESTUDIOS


01 febrero 2013

NEUROSURGERY. Feasibility, Safety, and Periprocedural Complications Associated With Endovascular Treatment of Selected Ruptured Aneurysms Under Conscious Sedation and Local Anesthesia

Kan, Peter MD, MPH; Jahshan, Shady MD; Yashar, Parham MD; Orion, David MD; Webb, Sharon MD; Siddiqui, Adnan H. MD PhD; Hopkins, L. Nelson MD; Levy, Elad I. MD

BACKGROUND: Endovascular coil embolization of ruptured aneurysms is performed under general anesthesia at most centers for perceived improved image quality and patient safety.

22 diciembre 2012

STROKE. Mechanical Thrombolysis and Stenting in Acute Ischemic Stroke

Jan Gralla, MD, MSc; Caspar Brekenfeld, MD; Pasquale Mordasini, MD; Gerhard Schroth, MD

Acute ischemic stroke is one of the major sources of morbidity and mortality in the industrialized countries. The lifetime risk of stroke is estimated to be 1 in 5 for middle-aged women and 1 in 6 for men according to the Framingham Study.1 Outcome depends on the length of time between onset of symptoms and revascularization, the recanalization rate, and on whether or not intracranial hemorrhage occurs.2 A meta-analysis of 52 studies on thrombolysis outcome in 2066 patients showed that the chance of an independent life after stroke increases 4.4 times for patients with successful recanalization compared with patients without recanalization; mortality rate decreases 4-fold.2

02 agosto 2012

AMERICAN JOURNAL OF NEURORADIOLOGY. Evaluating CT Perfusion Using Outcome Measures of Delayed Cerebral Ischemia in Aneurysmal Subarachnoid Hemorrhage

P.C. Sanelli, N. Anumula, C.E. Johnson, J.P. Comunale, A.J. Tsiouris, H. Riina, A.Z. Segal, P.E. Stieg, R.D. Zimmerman and A.I. Mushlin

BACKGROUND AND PURPOSE: DCI is a serious complication following aneurysmal SAH and remains a leading cause of morbidity and mortality. Our aim was to evaluate CTP in aneurysmal SAH by using outcome measures of DCI.

01 enero 2013

EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. Current Status of Clinical Magnetic Resonance Imaging for Plaque Characterisation in Patients with Carotid Artery Stenosis

A.G. den Hartog , S.M. Bovens , W. Koning , J. Hendrikse , P.R. Luijten , F.L. Moll , G. Pasterkamp , G.J. de Borst

Objective: The article aims to provide an overview of the literature that assessed the agreement between magnetic resonance imaging (MRI) and histology for specific carotid plaque characteristics associated with vulnerability in terms of sensitivity and specificity.

19 julio 2012

AMERICAN JOURNAL OF NEURORADIOLOGY. Microcatheter to Recanalization (Procedure Time) Predicts Outcomes in Endovascular Treatment in Patients with Acute Ischemic Stroke: When Do We Stop?

A.E. Hassan, S.A. Chaudhry, J.T. Miley, R. Khatri, S.A. Hassan, M.F.K. Suri and A.I. Qureshi

BACKGROUND AND PURPOSE: Endovascular treatment for acute ischemic stroke consists of various mechanical and pharmacologic modalities used for recanalization of arterial occlusions. We performed this study to determine the relationship among procedure time, recanalization, and clinical outcomes in patients with acute ischemic stroke undergoing endovascular treatment.

01 febrero 2013

NEUROSURGERY. Results of Stent-Assisted vs Non-Stent-Assisted Endovascular Therapies in 489 Cerebral Aneurysms: Single-Center Experience

Jahshan, Shady MD; Abla, Adib A. MD; Natarajan, Sabareesh K. MD, MS; Drummond, Patrick S. BS; Kan, Peter MD, MPH; Karmon, Yuval MD; Snyder, Kenneth V. MD, PhD; Hopkins, L. Nelson MD; Siddiqui, Adnan H. MD, PhD; Levy, Elad I. MD

BACKGROUND: Whether the addition of stenting to intracranial aneurysm coil embolization results in benefit in terms of occlusion rates or additional risk in terms of periprocedural adverse events is not clear.

08 diciembre 2011

STROKE. The Safety of Intravenous Thrombolysis for Ischemic Stroke in Patients With Pre-Existing Cerebral Aneurysms. A Case Series and Review of the Literature

Nancy J. Edwards, MD; Hooman Kamel, MD; S. Andrew Josephson, MD

Background and Purpose—Unruptured cerebral aneurysms are currently considered a contraindication to intravenous tissue-type plasminogen activator for acute ischemic stroke. This is due to a theoretical increase in the risk of hemorrhage from aneurysm rupture, although it is unknown whether this risk is a significant one. We sought to determine the safety of intravenous tissue-type plasminogen activator administration in a cohort of patients with pre-existing aneurysms.

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