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ESTUDIOS


01 septiembre 2012

JOURNAL OF CEREBROVASCULAR AND ENDOVASCULAR NEUROSURGERY. Bilateral Approach for Stent-assisted Coiling of Posterior Inferior Cerebellar Artery Aneurysms - Two Cases

Se-Il Jeon, MD, Bae Ju Kwon, MD, PhD, Dae-Hee Seo, MD, PhD,1 Hee In Kang, MD, PhD, Sung-Choon Park, MD, PhD, Il-Seung Choe, MD, PhD

Aneurysms of the posterior inferior cerebellar artery (PICA) are rarely encountered. In particular, due to frequent anatomic complexity and the presence of nearby critical structures, PICA origin aneurysms are difficult to treat. However, recent reports of anecdotal cases using advanced endovascular instruments and skills have made the results of endovascular treatment rather outstanding. PICA preservation is the key to a successful endovascular treatment, based on the premise that a PICA origin aneurysm is well occluded. To secure PICA flow, stenting into the PICA would be the best method, however, it is nearly impossible technically via the ipsilateral vertebral artery (VA) if the PICA arose at an acute angle from the sac. In such a case, a bilateral approach for stent-assisted coiling can be a creative method for achievement of two goals of both aneurysm occlusion and PICA preservation: ipsilateral approach for coil delivery and contralateral cross-over approach for stent delivery via a retrograde smooth path into the PICA.

01 septiembre 2012

JOURNAL OF CEREBROVASCULAR AND ENDOVASCULAR NEUROSURGERY. Intracranial Dural Arteriovenous Fistulas: Clinical Characteristics and Management Based on Location and Hemodynamics

Jung Tae Oh, MD, Seung Young Chung, MD, Giuseppe Lanzino, MD, Ki Seok Park, MD, Seong Min Kim, MD, Moon Sun Park, MD, Han Kyu Kim, MD

Objective: A dural arteriovenous fistula (DAVF) generally refers to a vascular malformation of the wall of a major venous sinus. These lesions have diverse symptoms according to the location and venous drainage, and require multidisciplinary treatment. We report on our experience and analyze the treatment outcome of intracranial DAVFs for a nine-year period. Methods:Between January 2000 and December 2008, 95 patients with intracranial DAVFs were enrolled in this study. A retrospective review of clinical records and imaging studies of all patients was conducted. Endovascular embolization, surgical interruption, gamma knife stereotactic radiosurgery (GKS), or combinations of these treatments were performed based on clinical symptoms, lesion location, and venous drainage pattern. Results:Borden type I, II, and III were 34, 48, and 13 patients, respectively. Aggressive presentation was reported in 6% of Borden type I, 31% of Borden type II, and 77% of Borden type III DAVFs, respectively, and DAVFs involving transverse, sigmoid, and superior sagittal sinus. Overall, the rate of complete obliteration was 68%. The complete occlusion rates with a combination treatment of endovascular embolization and surgery, surgery alone, and endovascular embolization were 89%, 86%, and 80%, respectively. When GKS was used with embolization, the obliteration rate was 83%, although it was only 54% in GKS alone. Spontaneous obliteration of the DAVF occurred in three patients. There were a few complications, including hemiparesis (in microsurgery), intracranial hemorrhage (in endovascular embolization), and facial palsy (in GKS). Conclusion:The hemorrhagic risk of DAVFs is dependent on the location and hemodynamics of the lesions. Strategies for treatment of intracranial DAVFs should be decided according to the characteristic of the DAVFs, based on the location and drainage pattern. GKS can be used as an optional treatment for intracranial DAVFs.

01 marzo 2012

STROKE. Thrombus Branching and Vessel Curvature Are Important Determinants of Middle Cerebral Artery Trunk Recanalization With Merci Thrombectomy Devices

Liangfu Zhu, MD, PhD; David S. Liebeskind, MD; Reza Jahan, MD; Sidney Starkman, MD; Noriko Salamon, MD; Gary Duckwiler, MD; Fernando Vinuela, MD; Satoshi Tateshima, MD; Nestor Gonzalez, MD; Pablo Villablanca, MD; Latisha K. Ali, MD; Doojin Kim, MD; Bruce Ovbiagele, MD; Michael Froehler, MD; Matthew Tenser, MD; Jeffrey L. Saver, MD

Background and Purpose—Determinants of successful recanalization likely differ for Merci thrombectomy and intra-arterial pharmacological fibrinolysis interventions. Although the amount of thrombotic material to be digested is an important consideration for chemical lysis, mechanical debulking may be more greatly influenced by other target lesion characteristics.

01 marzo 2013

NEUROSURGERY. Infection Risk in Neurointervention and Cerebral Angiography

Kelkar, Prashant S. DO; Fleming, J. Brett MD; Walters, Beverly C. MD, MSc; Harrigan, Mark R. MD

BACKGROUND: The risk of infection with cerebral angiography and neurointerventional procedures has not been defined. Likewise, although the use of routine prophylactic antibiotics has been advocated by some neurointerventionalists, the utility of prophylactic antibiotics in this setting has not been determined.

16 marzo 2012

INTERVENTIONAL NEURORADIOLOGY. Endovascular Treatment of Tentorial Dural Arteriovenous Fistulae

E. Wajnberg, G. Spilberg, M.T. Rezende, D.G Abud, I. Kessler, C. Mounayer, and Association of Rothschild Foundation Alumni (ARFA)

Tentorial dural arteriovenous fistula (DAVF) is a rare vascular disease, which accounts for less than 4% of all cases of intracranial DAVF. Because of the high risk of intracranial hemorrhage, patients with tentorial DAVF need aggressive treatment. Management approaches are still controversial, and endovascular treatment has emerged as an effective alternative. In the current work, we describe our experience with the endovascular approach in the treatment of these deep and complex DAVF of the tentorium.

01 septiembre 2012

JOURNAL OF CEREBROVASCULAR AND ENDOVASCULAR NEUROSURGERY. A Ruptured Aneurysm at the Infraoptic Azygous Anterior Cerebral Artery with the Contralateral Internal Carotid Artery Agenesis Treated by Y-stent Assisted Coil Embolization

Ho-Jun Kang, MD, Yoon-Soo Lee, MD, Sang-Jun Suh, MD, Jeong-Ho Lee, MD, Kee-Young Ryu, MD, Dong-Gee Kang, MD

Infraoptic anterior cerebral artery (ACA) is an extremely rare congenital anomaly. This anomalous artery usually arises from the intradural internal carotid artery (ICA) near the level of the ophthalmic artery (OA) or rarely from the extradural ICA. This anomaly frequently harbors a cerebral aneurysm, and may involve other coexisting vascular anomalies. In the case of this anomaly, surgical treatment of the aneurysm at the proximal ACA or anterior communicating artery (ACoA) may sometimes be difficult, because the veiled proximal ACA by the optic nerve would make proximal control inconvenient and the vertical midline segment of the proximal ACA would frequently form a superiorly directing aneurysm with a relatively high position. We report on an extremely rare case of a ruptured aneurysm at the infraoptic azygous ACA, possibly having an extradural origin, accompanied by contralateral ICA agenesis, and also introduce a feasible method for treatment by Y-stent assisted coil embolization.

01 marzo 2012

STROKE. Residual Flow After Cerebral Aneurysm Coil Occlusion

Pascale Lavoie, MD; Jean-Luc Gariépy, MD; Geneviève Milot, MD; Steve Jodoin, MD; Fernand Bédard, MD; Francois Trottier, MD; René Verreault, MD

Background and Purpose—The purpose of this study was to estimate the performance measures of MR angiography (MRA) in the diagnosis of aneurysm residual flow after coil occlusion.

01 marzo 2013

STROKE. Stroke Risk After Posterior Circulation Stroke/Transient Ischemic Attack and its Relationship to Site of Vertebrobasilar Stenosis

Giosue Gulli, MD; Lars Marquardt, MD; Peter M. Rothwell, FMed Sci; Hugh S. Markus, FRCP

Background and Purpose—Recent prospective studies have shown vertebrobasilar (VB) stenosis predicts stroke risk in posterior circulation stroke and transient ischemic attack. It is unclear whether this association is independent of other risk factors, and whether intracranial or extracranial stenosis confers different risks.

01 febrero 2013

ASIAN JOURNAL OF NEUROSURGERY. The study of flow diversion effects on aneurysm using multiple enterprise stents and two flow diverters

Masahiro Kojima, Keiko Irie, Toshio Fukuda, Fumihito Arai, Yuichi Hirose, Makoto Negoro

Background: Computer-based simulation is necessary to clarify the hemodynamics in brain aneurysm. Specifically for endovascular treatments, the effects of indwelling intravascular devices on blood stream need to be considered. The most recent technology used for cerebral aneurysm treatment is related to the use of flow diverters to reduce the amount of flow entering the aneurysm. To verify the differences of flow reduction, we analyzed multiple Enterprise stents and two kinds of flow diverters.

01 marzo 2013

JOURNAL OF NEUROINTERVENTIONAL SURGERY. Management of subarachnoid hemorrhage with intracerebral hematoma: clipping and clot evacuation versus coil embolization followed by clot evacuation

Kenneth de los Reyes, Aman Patel, Joshua B Bederson, Jennifer A Frontera

Background Aneurysmal subarachnoid hemorrhage (SAH) with associated intracerebral hemorrhage (ICH) is often treated with concomitant surgical clipping and ICH evacuation. The aim of this study was to determine if aneurysm coiling followed by ICH evacuation is a viable alternative treatment.

01 junio 2012

JOURNAL OF CEREBROVASCULAR AND ENDOVASCULAR NEUROSURGERY. Delayed Symptomatic Thromboembolism After Unruptured Middle Cerebral Artery Aneurysm Embolization

Hye-Jin Kim, MD,1 Taek Jun Lee, MD,1 Sun-il Lee, MD,2 Sung-Chul Jin, MD2

INTRODUCTION: Endovascular coil embolization has been an effective treatment modality for the treatment of unruptured intracranial aneurysms. However, major procedural complications have occasionally occurred, including thromboembolism and aneurysm perforation. In addition, vasospasm, hemodynamic ischemia, migration or reconfiguration of coils and subsequent enlargement of the neck or sac were recognized as pivotal limitations of endovascular coil embolization.8) Thromboembolic events are the most common complication of endovascular treatment, and they may be caused by thrombus formation from the catheter or guidewire, or breakdown of the thrombus from the aneurysm, in which coils have been packed, into the parent artery.5) Most thromboembolic complications occur within 48 hours of endovascular treatment; therefore, antiplatelet or anticoagulant is used during the procedure.1) However, delayed thromboembolic event beyond 2 days after coil embolization may occur despite its rarity. Here, we present a case of delayed symptomatic thromboembolism which occurred 19 days after the coil embolization of an unruptured aneurysm despite antiplatelet therapy.

01 septiembre 2012

JOURNAL OF CEREBROVASCULAR AND ENDOVASCULAR NEUROSURGERY. The Relationship Between Subarachnoid Hemorrhage Volume and Development of Cerebral Vasospasm

Sang-Won Jung, MD, Chang-Young Lee, MD, Man-Bin Yim, MD

Objective: The objective of this study is to verify the relationship between subarachnoid hemorrhage (SAH) volume (not Fisher grade) and development of cerebral vasospasm prospectively. Methods:Patients who visited our hospital with a diffuse or localized thick subarachnoid blood clot seen on computed tomography (CT), taken within 48 hours after SAH and the aneurysm was confirmed by CT Angiogram (CTA) from March 2010 to July 2011 were enrolled in this study. CTA was checked at least twice after admission. Angiographic vasospasm (AVS) on CTA was defined as irregularity or narrowing of intracranial vessels on follow up CTA compared with initial CTA. Total intracranial hemorrhage (ICH) volume (subdural, SAH, intracerebral and intraventricular) was calculated and SAH volume (all supratentorial and infratentorial cisterns) was also calculated using the MIPAV software package. Results:A total of 55 patients were included in our study. Thirty six patients did not show AVS on CTA or clinical deterioration (non vasospasm group: NVS). AVS without ischemic neurologic symptoms was observed in four patients and development of symptomatic vasospasm (SVS), defined as AVS with ischemic symptoms, was observed in 15 patients. SAH volume in SVS patients was statistically larger than that in NVS patients (p < 0.05). Total ICH volume in SVS patients was larger than that in NVS patients. However, the difference was not statistically significant. Conclusion:Results of this study indicate an association of development of vasospasm with the SAH volume, not intracranial hemorrhage.

01 marzo 2012

STROKE. Lumbar Drainage of Cerebrospinal Fluid After Aneurysmal Subarachnoid Hemorrhage. A Prospective, Randomized, Controlled Trial (LUMAS)

Yahia Z. Al-Tamimi, MRCS; Deepti Bhargava, MRCS; Richard G. Feltbower, PhD; Gregory Hall, PhD; Anthony J.P. Goddard, FRCR; Audrey C. Quinn, FFARCSI; Stuart A. Ross, FRCS(SN)

Background and Purpose—A single-center prospective randomized controlled trial has been conducted to determine if lumbar drainage of cerebrospinal fluid after aneurysmal subarachnoid hemorrhage reduces the prevalence of delayed ischemic neurological deficit and improves clinical outcome.

01 marzo 2013

NEUROSURGERY. The Role of Radiosurgery to the Tumor Bed After Resection of Brain Metastases

Gans, Jared H. BS; Raper, Daniel M.S. MBBS; Shah, Ashish H. BS; Bregy, Amade MD, PhD; Heros, Deborah MD; Lally, Brian E. MD; Morcos, Jacques J. MD; Heros, Roberto C. MD; Komotar, Ricardo J. MD

OBJECTIVE: To conduct a systematic review of the literature to understand the role of postoperative stereotactic radiosurgery after resection of brain metastases.

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