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ESTUDIOS


01 noviembre 2013

AMERICAN JOURNAL OF NEURORADIOLOGY. 4D CT Angiography More Closely Defines Intracranial Thrombus Burden Than Single-Phase CT Angiography

A.M.J. Frölicha, D. Schradera, E. Klotzc, R. Schramma, K. Wasserb, M. Knautha and P. Schramma

BACKGROUND AND PURPOSE: In patients with acute stroke, the location and extent of intravascular thrombi correlate with clinical and imaging outcomes and have been used to predict the success of intravenous thrombolysis. We hypothesized that 4D-CTA reconstructed from whole-brain CTP more closely outlines intracranial thrombi than conventional single-phase CTA.

01 noviembre 2013

STROKE. Modelling the Efficiency of Local Versus Central Provision of Intravenous Thrombolysis After Acute Ischemic Stroke

Peter McMeekin, PhD; Jo Gray, MSc; Gary A. Ford, MBBChir; Helen Rodgers, MBChB; Christopher I. Price, MD

Background and Purpose—Prehospital redirection of stroke patients to a regional center is used as a strategy to maximize the provision of intravenous thrombolysis. We developed a model to quantify the benefit of redirection away from local services that were already providing thrombolysis.

01 noviembre 2012

STROKE. Persistent Hemodynamic Changes in Ruptured Brain Arteriovenous Malformations

Till Illies, MD; Nils Daniel Forkert, MSc; Dennis Saering, PhD; Karolin Wenzel; Thorsten Ries, MD; Jan Regelsberger, MD; Karl Wegscheider, PhD; Jens Fiehler, MD

Background and Purpose—Hemodynamic properties of brain arteriovenous malformations (AVMs) with risk factors for a future hemorrhage are essentially unknown. We hypothesized that AVMs with anatomic properties, which are associated with an increased rupture risk, exhibit different hemodynamic characteristics than those without these properties.

01 noviembre 2013

AMERICAN JOURNAL OF NEURORADIOLOGY. Stroke Mismatch Volume with the Use of ABC/2 Is Equivalent to Planimetric Stroke Mismatch Volume

M. Lubya, J. Honga, J.G. Merinoa,b, J.K. Lyncha, A.W. Hsiaa,b, A. Magadána, S.S. Songd, L.L. Latoura and S. Waracha,e

BACKGROUND AND PURPOSE: In the clinical setting, there is a need to perform mismatch measurements quickly and easily on the MR imaging scanner to determine the specific amount of treatable penumbra. The objective of this study was to quantify the agreement of the ABC/2 method with the established planimetric method.

01 noviembre 2012

STROKE. Dramatic Recovery in Acute Ischemic Stroke Is Associated With Arterial Recanalization Grade and Speed

Mikael Mazighi, MD, PhD; Elena Meseguer, MD; Julien Labreuche, BST; Jean-Michel Serfaty, MD; Jean-Pierre Laissy, MD; Philippa C. Lavallée, MD; Lucie Cabrejo, MD; Céline Guidoux, MD; Bertrand Lapergue, MD; Isabelle F. Klein, MD, PhD; Jean-Marc Olivot, MD, PhD; Aymeric Rouchaud, MD; Jean-Philippe Desilles, MD; Elisabeth Schouman-Claeys, MD; Pierre Amarenco, MD

Background and Purpose—Dramatic recovery (DR) is a predictor of stroke outcome among others. However, after successful recanalization, systematic favorable outcome is not the rule. We sought to analyze the impact of recanalization on DR in patients with acute ischemic stroke eligible for any revascularization strategies (either intravenous or endovascular).

01 noviembre 2013

AMERICAN JOURNAL OF NEURORADIOLOGY. Association of CT Perfusion Parameters with Hemorrhagic Transformation in Acute Ischemic Stroke

A.R. Jaina, M. Jaina, A.R. Kanthalaa, D. Damaniaa, L.G. Steadc, H.Z. Wangb and B.S. Jahromia

BACKGROUND AND PURPOSE: Prediction of hemorrhagic transformation in acute ischemic stroke could help determine treatment and prognostication. With increasing numbers of patients with acute ischemic stroke undergoing multimodal CT imaging, we examined whether CT perfusion could predict hemorrhagic transformation in acute ischemic stroke.

01 noviembre 2012

STROKE. National Trends in Utilization and Outcomes of Endovascular Treatment of Acute Ischemic Stroke Patients in the Mechanical Thrombectomy Era

Ameer E. Hassan, DO; Saqib A. Chaudhry, MD; Mikayel Grigoryan, MD; Wondwossen G. Tekle, MD; Adnan I. Qureshi, MD

Background and Purpose—Because several new devices for mechanical thrombectomy have become available, the outcomes of patients undergoing endovascular treatment for acute ischemic stroke are expected to improve in the United States. We performed this analysis to evaluate trends in utilization of endovascular treatment and associated rates of death and disability among acute ischemic stroke patients over a 6-year period, including further assessment within age strata.

01 noviembre 2012

AMERICAN JOURNAL OF ROENTGENOLOGY. Dual-Energy CT Applications in Head and Neck Imaging

Thomas J. Vogl, Boris Schulz, Ralf W. Bauer, Timo Stöver, Robert Sader and Ahmed M. Tawfik

OBJECTIVE. Dual-energy scanning is a breakthrough in CT technology that has several applications in chest and abdominal imaging. Dual-energy CT also has potential for head and neck imaging. This review describes the role of dual-energy CT in head and neck imaging.

01 noviembre 2012

AMERICAN JOURNAL OF NEURORADIOLOGY. Hemodynamic Alterations in Vertebrobasilar Large Artery Disease Assessed by Arterial Spin-Labeling MR Imaging

B.J. MacIntosha,b,b, L. Marquardta,d, U.G. Schulza, P. Jezzarda and P.M. Rothwella

BACKGROUND AND PURPOSE: VB artery stenosis is associated with a high risk of recurrent ischemic events, and knowledge about the hemodynamic relevance of VB stenosis is important for clinical decision making. In this study, multiple inflow pulsed ASL MR imaging was assessed for its ability to measure CBF and ATT in patients with VB disease.

01 octubre 2013

NEUROSURGERY. Perioperative Complications After Carotid Artery Stenting: A Contemporary Experience From the University at Buffalo Neuroendovascular Surgery Team

Dumont, Travis M. MD*,‡; Wach, Michael M. BS‡; Mokin, Maxim MD, PhD*,‡; Sorkin, Grant C. MD*,‡; Snyder, Kenneth V. MD, PhD*,‡,§,‖; Hopkins, L. Nelson MD*,‡,§,‖,¶; Levy, Elad I. MD*,‡,§; Siddiqui, Adnan H. MD, PhD*,‡,§

BACKGROUND: Technological advances have resulted in diminishing perioperative complications reported during carotid artery stenting (CAS) trials. Because trial experience lags behind technological advances, an understanding of the incidence of perioperative complications after CAS remains in flux.

01 octubre 2013

STROKE. Endovascular Therapy for Asymptomatic Unruptured Intracranial Aneurysms. JR-NET and JR-NET2 Findings

Tomoyoshi Shigematsu, MD; Toshiyuki Fujinaka, MD, PhD; Toshiki Yoshimine, MD, PhD; Hirotoshi Imamura, MD, PhD; Akira Ishii, MD, PhD; Chiaki Sakai, MD, PhD; Nobuyuki Sakai, MD, DMSc for the JR-NET Investigators

Background and Purpose—National registration studies (the Japanese Registry of Neuroendovascular Therapy [JR-NET] and JR-NET2) have determined the current status and outcomes of neuroendovascular therapy (neuro-EVT). We analyzed short-term outcomes of EVT for asymptomatic unruptured intracranial aneurysms (UIAs).

01 septiembre 2013

STROKE. Prospective, Multicenter, Single-Arm Study of Mechanical Thrombectomy Using Solitaire Flow Restoration in Acute Ischemic Stroke

Vitor M. Pereira, MD, MSc; Jan Gralla, MD, MSc; Antoni Davalos, MD; Alain Bonafé, MD; Carlos Castaño, MD, PhD; René Chapot, MD; David S. Liebeskind, MD; Raul G. Nogueira, MD; Marcel Arnold, MD; Roman Sztajzel, MD; Thomas Liebig, MD; Mayank Goyal, MD; Michael Besselmann, MD; Alfredo Moreno, MD; Gerhard Schroth, MD

Background and Purpose—Mechanical thrombectomy using stent retriever devices have been advocated to increase revascularization in intracranial vessel occlusion. We present the results of a large prospective study on the use of the Solitaire Flow Restoration in patients with acute ischemic stroke.

01 agosto 2013

STROKE. Cost-Effectiveness of Thrombolysis Within 4.5 Hours of Acute Ischemic Stroke Experience From Australian Stroke Center

Sharman P. Tan Tanny, BmedSci; Lucy Busija, PhD; Danny Liew, MBBS, PhD, FRACP; Sarah Teo; Stephen M. Davis, MBBS, MD, FRACP; Bernard Yan, MBBS, FRACP

Background and Purpose—Previous economic studies outside Australia have demonstrated that patients treated with tissue-type plasminogen activator (tPA) within 4.5 hours of stroke onset have lower healthcare costs than those not. We aim to perform cost-effectiveness analysis of intravenous tPA in an Australian setting.

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