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ESTUDIOS


01 noviembre 2012

STROKE. Bigger, Faster? Associations Between Hospital Thrombolysis Volume and Speed of Thrombolysis Administration in Acute Ischemic Stroke

Benjamin D. Bray, MRCP; James Campbell, LLB; Geoffrey C. Cloud, FRCP; Alex Hoffman, MSc; Pippa J. Tyrrell, FRCP; Charles D.A. Wolfe, FFPHM; Anthony G. Rudd, FRCP on behalf of the Intercollegiate Stroke Working Party Group

Background and Purpose—There is evidence that high-volume hospitals may produce better patient outcomes. We aimed to identify whether there were any associations between hospital thrombolysis volume and speed of thrombolysis (tissue-type plasminogen activator [tPA]) administration in patients with ischemic stroke.

01 noviembre 2013

NEURORADIOLOGY. Radiation dose in neuroangiography using image noise reduction technology: a population study based on 614 patients

Michael Söderman, Maria Mauti, Sjirk Boon, Artur Omar, María Marteinsdóttir, Tommy Andersson, Staffan Holmin, Bart Hoornaert

Introduction: The purpose of this study was to quantify the reduction in patient radiation dose by X-ray imaging technology using image noise reduction and system settings for neuroangiography and to assess its impact on the working habits of the physician.

01 noviembre 2013

AMERICAN JOURNAL OF NEURORADIOLOGY. Intracranial 4D Flow MRI: Toward Individualized Assessment of Arteriovenous Malformation Hemodynamics and Treatment-Induced Changes

S.A. Ansaria,b, S. Schnella, T. Carrolla,c, P. Vakila,c, M.C. Hurleya,b, C. Wuc, J. Carra, B.R. Bendoka,b, H. Batjerb and M. Markla,c

BACKGROUND AND PURPOSE: Arteriovenous malformations are an important etiology of hemorrhagic stroke. However, current imaging modalities and risk do not provide insights into individual AVM hemodynamics and its role in pathophysiology. The aims of this study are to determine whether intracranial 4D flow MR imaging can provide insights into arteriovenous malformation hemodynamics independent of the Spetzler-Martin grade and to report the changes in flow observed during staged embolization.

01 noviembre 2012

STROKE. Conjugate Eye Deviation in Acute Intracerebral Hemorrhage. Stroke Acute Management With Urgent Risk-Factor Assessment and Improvement–ICH (SAMURAI-ICH) Study

Shoichiro Sato, MD; Masatoshi Koga, MD; Hiroshi Yamagami, MD; Satoshi Okuda, MD; Yasushi Okada, MD; Kazumi Kimura, MD; Yoshiaki Shiokawa, MD; Jyoji Nakagawara, MD; Eisuke Furui, MD; Yasuhiro Hasegawa, MD; Kazuomi Kario, MD; Shoji Arihiro, MD; Kazuyuki Nagatsuka, MD; Kazuo Minematsu, MD; Kazunori Toyoda, MD

Background and Purpose—Conjugate eye deviation (CED) occurs frequently in patients with acute stroke. The purpose of this study was to elucidate the factors that correlate with CED as well as the relationship between CED and outcomes in patients with acute intracerebral hemorrhage.

01 noviembre 2013

NEURORADIOLOGY. Statement of ESMINT and ESNR regarding recent trials evaluating the endovascular treatment at the acute stage of ischemic stroke

L. Pierot, M. Söderman, M. Bendszus, P. White, M. Muto, F. Turjman, S. Mangiafico, J. Gralla, J. Fiehler, I. Szikora, C. Cognard

Background: Three recent, simultaneous publications report the neutral results of three randomized studies (SYNTHESIS Expansion, Interventional Management of Stroke (IMS) III, and Mechanical Retrieval and Recanalization of Stroke Clots Using Embolectomy (MR RESCUE)) comparing IV thrombolysis therapy or standard care (MR RESCUE) to the endovascular treatment (EVT) of acute ischemic stroke (AIS) [1–3]. The results of these three trials might lead to the erroneous conclusion that endovascular treatment has no or little place in the management of AIS. However, careful analysis of the IMS III, SYNTHESIS, and MR RESCUE studies is mandatory prior to assessment of the value of EVT of AIS. Also, the limits of the current and future trials should be outlined.

01 noviembre 2013

AMERICAN JOURNAL OF NEURORADIOLOGY. 4D CT Angiography More Closely Defines Intracranial Thrombus Burden Than Single-Phase CT Angiography

A.M.J. Frölicha, D. Schradera, E. Klotzc, R. Schramma, K. Wasserb, M. Knautha and P. Schramma

BACKGROUND AND PURPOSE: In patients with acute stroke, the location and extent of intravascular thrombi correlate with clinical and imaging outcomes and have been used to predict the success of intravenous thrombolysis. We hypothesized that 4D-CTA reconstructed from whole-brain CTP more closely outlines intracranial thrombi than conventional single-phase CTA.

01 noviembre 2013

STROKE. Modelling the Efficiency of Local Versus Central Provision of Intravenous Thrombolysis After Acute Ischemic Stroke

Peter McMeekin, PhD; Jo Gray, MSc; Gary A. Ford, MBBChir; Helen Rodgers, MBChB; Christopher I. Price, MD

Background and Purpose—Prehospital redirection of stroke patients to a regional center is used as a strategy to maximize the provision of intravenous thrombolysis. We developed a model to quantify the benefit of redirection away from local services that were already providing thrombolysis.

01 noviembre 2012

STROKE. Persistent Hemodynamic Changes in Ruptured Brain Arteriovenous Malformations

Till Illies, MD; Nils Daniel Forkert, MSc; Dennis Saering, PhD; Karolin Wenzel; Thorsten Ries, MD; Jan Regelsberger, MD; Karl Wegscheider, PhD; Jens Fiehler, MD

Background and Purpose—Hemodynamic properties of brain arteriovenous malformations (AVMs) with risk factors for a future hemorrhage are essentially unknown. We hypothesized that AVMs with anatomic properties, which are associated with an increased rupture risk, exhibit different hemodynamic characteristics than those without these properties.

01 noviembre 2013

AMERICAN JOURNAL OF NEURORADIOLOGY. Stroke Mismatch Volume with the Use of ABC/2 Is Equivalent to Planimetric Stroke Mismatch Volume

M. Lubya, J. Honga, J.G. Merinoa,b, J.K. Lyncha, A.W. Hsiaa,b, A. Magadána, S.S. Songd, L.L. Latoura and S. Waracha,e

BACKGROUND AND PURPOSE: In the clinical setting, there is a need to perform mismatch measurements quickly and easily on the MR imaging scanner to determine the specific amount of treatable penumbra. The objective of this study was to quantify the agreement of the ABC/2 method with the established planimetric method.

01 noviembre 2012

STROKE. Dramatic Recovery in Acute Ischemic Stroke Is Associated With Arterial Recanalization Grade and Speed

Mikael Mazighi, MD, PhD; Elena Meseguer, MD; Julien Labreuche, BST; Jean-Michel Serfaty, MD; Jean-Pierre Laissy, MD; Philippa C. Lavallée, MD; Lucie Cabrejo, MD; Céline Guidoux, MD; Bertrand Lapergue, MD; Isabelle F. Klein, MD, PhD; Jean-Marc Olivot, MD, PhD; Aymeric Rouchaud, MD; Jean-Philippe Desilles, MD; Elisabeth Schouman-Claeys, MD; Pierre Amarenco, MD

Background and Purpose—Dramatic recovery (DR) is a predictor of stroke outcome among others. However, after successful recanalization, systematic favorable outcome is not the rule. We sought to analyze the impact of recanalization on DR in patients with acute ischemic stroke eligible for any revascularization strategies (either intravenous or endovascular).

01 noviembre 2013

AMERICAN JOURNAL OF NEURORADIOLOGY. Association of CT Perfusion Parameters with Hemorrhagic Transformation in Acute Ischemic Stroke

A.R. Jaina, M. Jaina, A.R. Kanthalaa, D. Damaniaa, L.G. Steadc, H.Z. Wangb and B.S. Jahromia

BACKGROUND AND PURPOSE: Prediction of hemorrhagic transformation in acute ischemic stroke could help determine treatment and prognostication. With increasing numbers of patients with acute ischemic stroke undergoing multimodal CT imaging, we examined whether CT perfusion could predict hemorrhagic transformation in acute ischemic stroke.

01 noviembre 2012

STROKE. National Trends in Utilization and Outcomes of Endovascular Treatment of Acute Ischemic Stroke Patients in the Mechanical Thrombectomy Era

Ameer E. Hassan, DO; Saqib A. Chaudhry, MD; Mikayel Grigoryan, MD; Wondwossen G. Tekle, MD; Adnan I. Qureshi, MD

Background and Purpose—Because several new devices for mechanical thrombectomy have become available, the outcomes of patients undergoing endovascular treatment for acute ischemic stroke are expected to improve in the United States. We performed this analysis to evaluate trends in utilization of endovascular treatment and associated rates of death and disability among acute ischemic stroke patients over a 6-year period, including further assessment within age strata.

01 noviembre 2012

AMERICAN JOURNAL OF ROENTGENOLOGY. Dual-Energy CT Applications in Head and Neck Imaging

Thomas J. Vogl, Boris Schulz, Ralf W. Bauer, Timo Stöver, Robert Sader and Ahmed M. Tawfik

OBJECTIVE. Dual-energy scanning is a breakthrough in CT technology that has several applications in chest and abdominal imaging. Dual-energy CT also has potential for head and neck imaging. This review describes the role of dual-energy CT in head and neck imaging.

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