Foros de Conocimiento
medtronic PRODUCTOS
boston_scientific PRODUCTOS
TERUMO PRODUCTOS
Biotronik PRODUCTOS
Sirtex PRODUCTOS
Striker Neurovascular PRODUCTOS
BIOSENSORS PRODUCTOS

ESTUDIOS


01 noviembre 2014

CIRCULATION. Stroke and Outcomes in Patients With Acute Type A Aortic Dissection

Eduardo Bossone, MD, PhD; David C. Corteville, MD; Kevin M. Harris, MD; Toru Suzuki, MD, PhD; Rossella Fattori, MD; Stuart Hutchison, MD; Marek P. Ehrlich, MD; Reed E. Pyeritz, MD, PhD; Philippe Gabriel Steg, MD; Kevin Greason, MD; Arturo Evangelista, MD; Eva Kline-Rogers, MS, RN, NP; Daniel G. Montgomery, BS; Eric M. Isselbacher, MD; Christoph A. Nienaber, MD; Kim A. Eagle, MD

Background—Stroke is a highly dreaded complication of type A acute aortic dissection (TAAAD). However, little data exist on its incidence and association with prognosis.

01 agosto 2014

EUROPEAN HEART JOURNAL. Effect of renal denervation on left ventricular mass and function in patients with resistant hypertension: data from a multi-centre cardiovascular magnetic resonance imaging trial

Felix Mahfoud, Daniel Urban, Desiree Teller, Dominik Linz, Philipp Stawowy, Jan-Hendrik Hassel, Peter Fries, Stephan Dreysse, Ernst Wellnhofer, Günther Schneider, Arno Buecker, Christopher Schneeweis, Adelina Doltra, Markus P. Schlaich, Murray D. Esler, Eckart Fleck, Michael Böhm, Sebastian Kelle

Aims Sympathetic stimulation induces left ventricular hypertrophy and is associated with increased cardiovascular risk. Catheter-based renal denervation (RDN) has been shown to reduce sympathetic outflow and blood pressure (BP). The present multi-centre study aimed to investigate the effect of RDN on anatomic and functional myocardial parameters, assessed by cardiac magnetic resonance (CMR), in patients with resistant hypertension.

01 diciembre 2014

CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY. Safety and Efficacy of Bleomycin Sclerotherapy for Microcystic Lymphatic Malformation

Gulraiz Chaudry, Carlos J. Guevara, Kristy L. Rialon, Cindy Kerr, John B. Mulliken, Arin K. Greene, Steven J. Fishman, Debra Boyer, Ahmad I. Alomari

Sclerotherapy is the mainstay of treatment of macrocystic lymphatic malformation (LM), but the response using traditional sclerosants is much less beneficial in microcystic lesions. Intralesional bleomycin has been reported to be effective in microcystic LM; however, its use is limited by concerns about pulmonary fibrosis. The purpose of this study was to evaluate the safety and efficacy of bleomycin sclerotherapy in microcystic LM.

01 diciembre 2014

WORLD JOURNAL OF GASTROENTEROLOGY. Locally advanced rectal cancer: The importance of a multidisciplinary approach

Rossana Berardi, Elena Maccaroni, Azzurra Onofri, Francesca Morgese, Mariangela Torniai, Michela Tiberi, Consuelo Ferrini and Stefano Cascinu.

Rectal cancer accounts for a relevant part of colorectal cancer cases, with a mortality of 4-10/100000 per year. The development of locoregional recurrences and the occurrence of distant metastases both influences the prognosis of these patients. In the last two decades, new multimodality strategies have improved the prognosis of locally advanced rectal cancer with a significant reduction of local relapse and an increase in terms of overall survival. Radical surgery still remains the principal curative treatment and the introduction of total mesorectal excision has significantly achieved a reduction in terms of local recurrence rates. The employment of neoadjuvant treatment, delivered before surgery, also achieved an improved local control and an increased sphincter preservation rate in low-lying tumors, with an acceptable acute and late toxicity. This review describes the multidisciplinary management of rectal cancer, focusing on the effectiveness of neoadjuvant chemoradiotherapy and of post-operative adjuvant chemotherapy both in the standard combined modality treatment programs and in the ongoing research to improve these regimens.

01 diciembre 2014

WORLD JOURNAL OF GASTROENTEROLOGY. Transjugular intrahepatic portosystemic shunts and portal hypertension-related complications

Sith Siramolpiwat.

Portal hypertension (PH) plays an important role in the natural history of cirrhosis, and is associated with several clinical consequences. The introduction of transjugular intrahepatic portosystemic shunts (TIPS) in the 1980s has been regarded as a major technical advance in the management of the PH-related complications. At present, polytetrafluoroethylene-covered stents are the preferred option over traditional bare metal stents. TIPS is currently indicated as a salvage therapy in patients with bleeding esophageal varices who fail standard treatment. Recently, applying TIPS early (within 72 h after admission) has been shown to be an effective and life-saving treatment in those with high-risk variceal bleeding. In addition, TIPS is recommended as the second-line treatment for secondary prophylaxis. For bleeding gastric varices, applying TIPS was able to achieve hemostasis in more than 90% of patients. More trials are needed to clarify the efficacy of TIPS compared with other treatment modalities, including cyanoacrylate injection and balloon retrograde transvenous obliteration of gastric varices. TIPS should also be considered in bleeding ectopic varices and refractory portal hypertensive gastropathy. In patients with refractory ascites, there is growing evidence that TIPS not only results in better control of ascites, but also improves long-term survival in appropriately selected candidates. In addition, TIPS is a promising treatment for refractory hepatic hydrothorax. However, the role of TIPS in the treatment of hepatorenal and hepatopulmonary syndrome is not well defined. The advantage of TIPS is offset by a risk of developing hepatic encephalopathy, the most relevant post-procedural complication. Emerging data are addressing the determination the optimal time and patient selection for TIPS placement aiming at improving long-term treatment outcome. This review is aimed at summarizing the published data regarding the application of TIPS in the management of complications related to PH.

01 noviembre 2014

WORLD JOURNAL OF GASTROENTEROLOGY. Advances in non-surgical management of primary liver cancer

Xiao Chen, Hai-Peng Liu, Mei Li and Liang Qiao.

Hepatocellular carcinoma (HCC) is the fifth most common cancer and the third most common cause of cancer-related death worldwide. There have been great improvements in the diagnosis and treatment of HCC in recent years, but the problems, including difficult diagnosis at early stage, quick progression, and poor prognosis remain unsolved. Surgical resection is the mainstay of the treatment for HCC. However, 70%-80% of HCC patients are diagnosed at an advanced stage when most are ineligible for potentially curative therapies such as surgical resection and liver transplantation. In recent years, non-surgical management for unrespectable HCC, such as percutaneous ethanol injection, percutaneous microwave coagulation therapy, percutaneous radiofrequency ablation, transcatheter arterial chemoembolization, radiotherapy, chemotherapy, biotherapy, and hormonal therapy have been developed. These therapeutic options, either alone or in combination, have been shown to control tumor growth, prolong survival time, and improve quality of life to some extent. This review covers the current status and progress of non-surgical management for HCC.

Utilizamos cookies propias para el correcto funcionamiento del sitio web y mejorar nuestros servicios. Pulse el botón Aceptar todas para aceptar su uso. Puede cambiar la configuración u obtener más información en nuestra Política de cookies o pulsando Modificar configuración.