01 julio 2016

DIAGNOSTIC AND INTERVENTIONAL RADIOLOGY. Treatment of acute thoracic aortic syndromes using endovascular techniques

Emrah Uğuz, Murat Canyiğit, Mete Hıdıroğlu, Erol Şener

PURPOSE: Acute thoracic aortic syndrome (ATAS) is a novel term to define emergency aortic conditions with common clinical features and challenges. Traditional management of ATAS includes surgical replacement of the aorta and is correlated with high perioperative mortality and morbidity. We aimed to evaluate our experience and outcomes in patients presenting with ATAS, managed by endovascular techniques.

01 julio 2016

DIAGNOSTIC AND INTERVENTIONAL RADIOLOGY. Iatrogenic hemobilia: imaging features and management with transcatheter arterial embolization in 30 patients

Wen Feng, Dong Yue, Lu ZaiMing, Liu ZhaoYu, Zhao XiangXuan, Li Wei, Guo QiYong

PURPOSE: We aimed to evaluate the imaging features of computed tomography (CT) and angiography and the efficacy of transcatheter arterial embolization (TAE) in patients with hemobilia of different iatrogenic causes.

01 julio 2016

DIAGNOSTIC AND INTERVENTIONAL RADIOLOGY. Modified transarterial chemoembolization with locoregional administration of sorafenib for treating hepatocellular carcinoma: feasibility, efficacy, and safety in the VX-2 rabbit liver tumor model

Max Seidensticker, Sebastian Streit, Norbert Nass, Christian Wybranski, Julian Jürgens, Jan Brauner, Nadine Schulz, Thomas Kalinski, Ricarda Seidensticker, Benjamin Garlipp, Ingo Steffen, Jens Ricke, Oliver Dudeck

PURPOSE: We aimed to assess the feasibility, efficacy and safety of a local application of sorafenib within a conventional transarterial chemoembolization in the VX-2 tumor-bearing rabbit model.

01 julio 2016

DIAGNOSTIC AND INTERVENTIONAL RADIOLOGY. Transcatheter arterial embolization for traumatic mesenteric bleeding: a 15-year, single-center experience

Jong Soo Shin, Ji Hoon Shin, Heung-Kyu Ko, Jong Woo Kim, Hyun-Ki Yoon

PURPOSE: We aimed to assess the safety and effectiveness of transcatheter arterial embolization (TAE) for mesenteric bleeding following trauma.

01 septiembre 2016

RADIOLOGY. Management of Uterine Fibroids: A Focus on Uterine-sparing Interventional Techniques

James E. Silberzweig, MD, Daniel K. Powell, MD, Alan H. Matsumoto, MD, James B. Spies, MD, MPH

Uterine fibroids occur in approximately 50% of women over the age of 40 years, and an estimated 50% of those are symptomatic. Menorrhagia is the most common symptom and the primary indication for treatment, although bulk symptoms often occur and can be treated. Pharmacotherapy is typically inadequate unless it can be expected to successfully bridge to menopause or allow for a less-invasive intervention. However, hormonal therapies have risks. Hysterectomy is still the most commonly performed procedure for symptomatic fibroids and has the lowest rate of reintervention (compared with myomectomy or uterine artery embolization [UAE]), but rates of more serious complications are higher and patient satisfaction and ability to return to normal activities may also be less favorable. Myomectomy is not necessarily less morbid than hysterectomy and may have a greater failure rate than UAE. Techniques and devices vary with little standardization, and operator experience is crucial to success. The largest studies of UAE show very low rates of serious complications and rapid recovery. UAE significantly improves symptoms related to uterine fibroids in 85%–90% of patients. Herein, this article will discuss the nature of fibroids and their diagnosis, pharmacotherapy, surgical treatment, and nonsurgical interventional treatment, including UAE and magnetic resonance–guided focused ultrasound.

01 septiembre 2015

RADIOLOGY. CT Evaluation of Small-Diameter Coronary Artery Stents: Effect of an Integrated Circuit Detector with Iterative Reconstruction

Lucas L. Geyer, MD G. Russell Glenn, BS Carlo Nicola De Cecco, MD Mark Van Horn, PhD Christian Canstein, Dipl Phys Justin R. Silverman, BA Aleksander W. Krazinski, BA Jenny M. Kemper, MS Andreas Bucher, MD Ullrich Ebersberger, MD Philip Costello, MD Fabian Bamberg, MD, MPH U. Joseph Schoepf, MD

Purpose: To use suitable objective methods of analysis to assess the influence of the combination of an integrated-circuit computed tomographic (CT) detector and iterative reconstruction (IR) algorithms on the visualization of small (≤3-mm) coronary artery stents.

01 septiembre 2015

RADIOLOGY. Stress Myocardial Perfusion CT in Patients Suspected of Having Coronary Artery Disease: Visual and Quantitative Analysis—Validation by Using Fractional Flow Reserve

Dong Hyun Yang, MD, PhD Young-Hak Kim, MD, PhD Jae-Hyung Roh, MD Joon-Won Kang, MD, PhD Dongjin Han, PhD Joonho Jung, MS Namkug Kim, PhD Jung Bok Lee, PhD Jung-Min Ahn, MD, PhD Jong-Young Lee, MD, PhD Duk-Woo Park, MD, PhD Soo-Jin Kang, MD, PhD Seung-Whan Lee, MD, PhD Cheol Whan Lee, MD, PhD Seong-Wook Park, MD, PhD Seung-Jung Park, MD, PhD Tae-Hwan Lim, MD, PhD

Purpose: To assess the diagnostic accuracy of stress myocardial perfusion computed tomography (CT) by using visual and quantitative analytic methods in patients with coronary artery disease, with fractional flow reserve (FFR) as a reference standard.

01 septiembre 2015

RADIOLOGY. Subprosthetic Pannus after Aortic Valve Replacement Surgery: Cardiac CT Findings and Clinical Features

Kichang Han, MD Dong Hyun Yang, MD, PhD So Youn Shin, MD, PhD Namkug Kim, PhD Joon-Won Kang, MD, PhD Dae-Hee Kim, MD, PhD Jong-Min Song, MD, PhD Duk-Hyun Kang, MD, PhD Jae-Kwan Song, MD, PhD Joon Bum Kim, MD, PhD Sung-Ho Jung, MD, PhD Suk Jung Choo, MD, PhD Cheol Hyun Chung, MD, PhD Jae Won Lee, MD, PhD Tae-Hwan Lim, MD, PhD

Purpose: To investigate the cardiac computed tomographic (CT) findings and clinical implications of subprosthetic pannus in patients who have undergone aortic valve replacement.

01 septiembre 2015

RADIOLOGY. Aortic Dissection: Accurate Subintimal Flap Fenestration by Using a Reentry Catheter with Fluoroscopic Guidance—Initial Single-Institution Experience

Franziska Wolfschmidt, MD Nicole Hassold, MD Jan Peter Goltz, MD Rainer Leyh, MD Thorsten Alexander Bley, MD Ralph Kickuth, MD

Purpose: To evaluate the feasibility, effectiveness, and safety of using a commercially available reentry catheter with fluoroscopic guidance to gain controlled target lumen reentry for fenestration in patients with aortic dissection.

01 septiembre 2015

RADIOLOGY. Thyroid Biopsy Specialists: A Quality Initiative to Reduce Wait Times and Improve Adequacy Rates

Sangeet Ghai, MD Stefanie Y. Lee, MD Patrice M. Bret, MD Ravi J. Menezes, PhD Scott L. Boerner, MD Yongheng Jia, MBBS nKulsoom A. Maan, MBBS Rudolf Boci Wasim Javed, MBBS Mostafa Atri, MD

Purpose: To develop and implement a program where selected sonographers would be trained to perform thyroid biopsies independently under the supervision of a radiologist, with the goal of improving efficiency and quality.

01 septiembre 2015

RADIOLOGY. Efficacy and Safety of Radiofrequency Ablation for Treatment of Locally Recurrent Thyroid Cancers Smaller than 2 cm

Ji-hoon Kim, MD, PhD Won Sang Yoo, MD Young Joo Park, MD, PhD Do Joon Park, MD, PhD Tae Jin Yun, MD Seung Hong Choi, MD, PhD Chul-Ho Sohn, MD, PhD Kyu Eun Lee, MD, PhD Myung-Whun Sung, MD, PhD Yeo-Kyu Youn, MD, PhD Kwang Hyun Kim, MD, PhD Bo Youn Cho, MD, PhD

Purpose: To evaluate the efficacy and safety of radiofrequency ablation (RFA) for localized small recurrent thyroid cancers less than 2 cm by comparing them with those at repeat surgery.

01 agosto 2015

RADIOLOGY. Science to Practice: The Changing Face of Local Tumor Therapies—Do We Have to Think Systemically When Treating Cancer Locally?

Julius Chapiro, MD

In this issue, Rozenblum et al were able to demonstrate that radiofrequency (RF) ablation–induced liver regeneration promotes “off-target” tumorigenesis in a MDR2 knock-out mouse model of hepatocellular carcinoma (HCC) in the setting of chronic liver inflammation. In addition, the authors demonstrated that blocking liver regeneration with a c-met inhibitor might attenuate or eliminate potential tumorigenic effects. These results provide the rationale for combined therapeutic approaches of RF ablation followed by a systemic application of immunomodulatory drugs.

01 agosto 2015

RADIOLOGY. Radiofrequency Ablation: Inflammatory Changes in the Periablative Zone Can Induce Global Organ Effects, including Liver Regeneration

Nir Rozenblum, PhD Evelyne Zeira, BSc Baruch Bulvik, PhD Svetlana Gourevitch, BSc Hagit Yotvat, BSc Eithan Galun, MD, PhD S. Nahum Goldberg, MD

Purpose: To determine the kinetics of innate immune and hepatic response to the coagulation necrosis area that remains in situ after radiofrequency (RF) ablation, the cytokine profile of this response, and its local and global effect on the whole organ in a small-animal model.

01 agosto 2015

RADIOLOGY. Oncogenesis: An “Off-Target” Effect of Radiofrequency Ablation

Nir Rozenblum, PhD Evelyne Zeira, BSc Viviana Scaiewicz, MSc Baruch Bulvik, PhD Svetlana Gourevitch, BSc Hagit Yotvat, BSc Eithan Galun, MD, PhD S. Nahum Goldberg, MD

Purpose: To compare hepatocellular carcinoma (HCC) development after radiofrequency (RF) ablation, partial surgical hepatectomy, and a sham operation and to inhibit HCC recurrence after RF ablation in a mouse model of spontaneously forming HCC in the setting of chronic inflammation (ie, the MDR2 knockout model).

01 agosto 2015

RADIOLOGY. Single Hepatocellular Carcinoma: Preoperative MR Imaging to Predict Early Recurrence after Curative Resection

Chansik An, MD Dong Wook Kim, PhD Young-Nyun Park, MD Yong Eun Chung, MD Hyungjin Rhee, MD Myeong-Jin Kim, MD

Purpose: To identify magnetic resonance (MR) imaging features that enable prediction of early recurrence (<2 years) after curative resection of hepatocellular carcinoma (HCC) and to derive a preoperative prediction model.