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ESTUDIOS


01 enero 2012

TRIALS. Acute cholecystitis in high risk surgical patients: percutaneous cholecystostomy versus laparoscopic cholecystectomy (CHOCOLATE trial): Study protocol for a randomized controlled trial

Kirsten Kortram, Bert van Ramshorst, Thomas L Bollen, Marc GH Besselink, Dirk J Gouma, Tom Karsten, Philip M Kruyt, Grard AP Nieuwenhuijzen, Johannes C Kelder, Ellen Tromp and Djamila Boerma

Background: Laparoscopic cholecystectomy in acute calculous cholecystitis in high risk patients can lead to significant morbidity and mortality. Percutaneous cholecystostomy may be an alternative treatment option but the current literature does not provide the surgical community with evidence based advice.

01 febrero 2012

JOURNAL OF HEPATOLOGY. Radioembolization for hepatocellular carcinoma

Bruno Sangroemail address , Mercedes Iñarrairaegui , Jose I. Bilbao

Radioembolization is a form of brachytherapy in which intra-arterially injected 90Y-loaded microspheres serve as sources for internal radiation purposes. It produces average disease control rates above 80% and is usually very well tolerated. Main complications do not result from the microembolic effect, even in patients with portal vein occlusion, but rather from an excessive irradiation of non-target tissues including the liver. All the evidence that support the use of radioembolization in HCC is based on retrospective series or non-controlled prospective studies. However, reliable data can be obtained from the literature, particularly since the recent publication of large series accounting for nearly 700 patients. When compared to the standard of care for the intermediate and advanced stages (transarterial embolization and sorafenib), radioembolization consistently provides similar survival rates. Two indications seem particularly appealing in the boundaries of these stages for first-line radioembolization. First, the treatment of patients straddling between the intermediate and advanced stages (intermediate patients with bulky or bilobar disease that are considered poor candidates for TACE, and advanced patients with solitary tumors invading a segmental or lobar branch of the portal vein). Second, the treatment of patients that are slightly above the criteria for resection, ablation or transplantation, for which downstaging could open the door for a radical approach. Radioembolization can also be used to treat patients progressing to TACE or sorafenib. With a number of clinical trials underway, the available evidence shows that it adds a significant value to the therapeutic weaponry against HCC of tertiary care centers dealing with this major cancer problem.

01 mayo 2012

AMERICAN JOURNAL OF ROENTGENOLOGY. Simultaneous MR Arteriography and Venography With Blood Pool Contrast Agent Detects Deep Venous Thrombosis in Suspected Arterial Disease

Dariusch R. Hadizadeh, Guido M. Kukuk, Ute L. Fahlenkamp, Josephine Pressacco, Christian Schäfer, Eberhard Rabe, Arne Koscielny, Frauke Verrel, Hans H. Schild and Winfried A. Willinek

OBJECTIVE. The purpose of this study was to investigate the prevalence of incidental deep venous thrombosis (DVT) in patients with clinically suspected peripheral arterial occlusive disease (PAOD) using contrast-enhanced MR angiography (MRA) with a blood pool contrast agent.

01 abril 2013

ENDOVASCULAR TODAY. Ruby Detachable Coils

Claudio Schönholz, MD; James F. Benenati, MD; Frank Arko, MD; Corey Teigen, MD; and J David Moskovitz, MD

In 1960, Alfred J. Luessenhop and William T. Spence published the first article on embolization entitled “Artificial Embolization of Cerebral Arteries” in the Journal of the American Medical Association.1 It included a detailed case report of a young patient with a cerebral arteriovenous malformation that was treated by artificial embolization using “an embolus of predetermined size and configuration,” which was introduced far proximal to the malformation. This described one of the first embolization agents and techniques.

01 mayo 2012

AMERICAN JOURNAL OF ROENTGENOLOGY. Colorectal Liver Metastasis After 90Y Radioembolization Therapy: Pilot Study of Change in MDCT Attenuation as a Surrogate Marker for Future FDG PET Response

Sandra M. Tochetto, Hüseyin Gürkan Töre, Hamid Chalian and Vahid Yaghmai

OBJECTIVE. The purpose of this study was to investigate whether changes in attenuation and size of liver metastatic lesions of colorectal cancer at MDCT 1 month after 90Y radioembolization treatment are predictive of response at FDG PET 3 months after treatment.

01 abril 2013

ENDOVASCULAR TODAY. The Time Is Now for Transradial Intervention

Aaron M. Fischman, MD, and Rahul S. Patel, MD

Use of the radial artery as the primary access vessel into the arterial system for transcatheter diagnosis and intervention is not a new concept. The first series describing diagnostic angiography of the coronary circulation using transradial access (TRA) was published in 1989 by Lucien Campeau at the Montreal Heart Institute.1 Campeau suggested percutaneous radial access as a safer alternative to percutaneous and “cutdown” brachial or axillary access. His series of 100 patients demonstrated an 88% technical success rate and a 6% asymptomatic radial artery occlusion rate, which was a significant improvement over brachial/axillary upper arm access.1 Shortly thereafter, in 1992, Kiemeneij performed the first successful transradial (TR) coronary angioplasty procedure and then, in 1993, the first TR coronary stent placement via the radial artery.2 Since then, the utilization of this technique has significantly grown worldwide.

01 mayo 2012

CIRCULATION. Body Mass Index, Surgery, and Risk of Venous Thromboembolism in Middle-Aged Women. A Cohort Study

Lianne Parkin, MB, ChB, PhD; Sian Sweetland, DPhil; Angela Balkwill, MSc; Jane Green, MB, ChB, DPhil; Gillian Reeves, PhD; Valerie Beral, MD, FRS for the Million Women Study Collaborators

Background—Obesity and surgery are known risk factors for venous thromboembolism (VTE), but there is limited information about the independent effects of obesity on the incidence of postoperative VTE. We linked questionnaire data from the Million Women Study with hospital admission and death records to examine the risk of VTE in relation to body mass index (BMI) both in the absence of surgery and in the first 12 weeks following an operation.

01 mayo 2013

DIAGNOSTIC AND INTERVENTIONAL RADIOLOGY. Occlusion of a neo-esophageal-bronchial fistula using the Amplatzer Vascular Plug 2

Jamie A. Young, Sami M. Shimi, Afhsin Alijani, Pradeep V. Patil, Raj Bhat

The appearance of a benign fistula between the airway and the gastrointestinal tract is a rare complication of esophagectomy. We report a patient with neo-esophago-bronchial fistula that developed 13 months after two-stage esophagectomy. Repeat thoracotomy was not deemed appropriate given the patient’s chronic sepsis and malnutrition. After unsuccessful attempts at endoscopic closure, the fistula was successfully and permanently occluded under radiological guidance with an Amplatzer® Vascular Plug 2. The patient remained asymptomatic, with a measured weight gain, 12 months after the successful fistula occlusion.

01 abril 2013

ENDOVASCULAR TODAY. Special Considerations for Embolization in Trauma Cases

Jason Salsamendi, MD; David Quintana, MD; Issam Kably, MD; and Govindarajan Narayanan, MD

One of the most preventable causes of death in abdominal and pelvic trauma is arterial hemorrhage that goes untreated or unrecognized.1 Over the last decade, radiology has undergone many advances, particularly in noninvasive imaging and interventional angiography, such that critical arterial hemorrhage is both recognized and treated faster, often with life-preserving results. The cornerstone of arterial hemostasis is early intervention, whether via endovascular techniques, open laparotomy, or a combination of both. Early intervention requires a highly sensitive and specific diagnostic study that can be performed and interpreted quickly.

01 marzo 2013

SEMINARS IN INTERVENTIONAL RADIOLOGY. Radiofrequency Ablation of Liver Tumors

Shaunagh McDermott, Debra A. Gervais

Radiofrequency ablation (RFA) is an alternative therapy for hepatocellular carcinoma and liver metastases when resection cannot be performed or, in the case of hepatocellular carcinoma, when transplant cannot be performed in a timely enough manner to avoid the risk of dropping off the transplant list. RFA has the advantage of being a relatively low-risk minimally invasive procedure used in the treatment of focal liver tumors. This review article discusses the current evidence supporting RFA of liver tumors, as well as the indications, complications, and follow-up algorithms used after RFA.

01 mayo 2012

RADIOLOGY. Placement of Marker Coils at Biopsy: Usefulness in the Localization of Poorly Visualized Renal Neoplasms for Subsequent CT-guided Radiofrequency Ablation

Jason A. Pietryga, MD, Michael D. Beland, MD, Damian E. Dupuy, MD and William W. Mayo-Smith, MD

Purpose: To determine whether placement of marking coils at biopsy of small renal neoplasms to facilitate localization at subsequent radiofrequency (RF) ablation is safe and can reduce fluoroscopy time during the ablative procedure.

01 mayo 2012

AMERICAN JOURNAL OF ROENTGENOLOGY. Locoregional Chemoembolic Delivery: Prediction With Transcatheter Intraarterial Perfusion MRI

Ron C. Gaba, Brian Jin, Dingxin Wang, Robert J. Lewandowski, Ann B. Ragin, Andrew C. Larson, Riad Salem and Reed A. Omary

OBJECTIVE. To our knowledge there is currently no quantitative preprocedural method for predicting the distribution and selectivity of delivery of chemoembolic material during trans–arterial chemoembolization. Transcatheter intraarterial perfusion MRI has been developed as a method of quantifying hepatic arterial perfusion. The purpose of this study was to investigate whether findings at transcatheter intraarterial perfusion MRI before chemoembolization can be used to predict uptake of the chemoembolic material delivered during chemoembolization.

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