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ESTUDIOS


01 septiembre 2012

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Paclitaxel-Coated Versus Uncoated Balloon Angioplasty Reduces Target Lesion Revascularization in Patients With Femoropopliteal Arterial Disease. A Meta-Analysis of Randomized Trials

Salvatore Cassese, MD*, Robert A. Byrne, MB, BCh, PhD*, Ilka Ott, MD, Gjin Ndrepepa, MD, Mateja Nerad, MD, Adnan Kastrati, MD and Massimiliano Fusaro, MD

Background—In disease of the femoropopliteal artery, paclitaxel-coated balloon (PCB) therapy improved angiographic outcomes as compared with uncoated balloon (UCB) angioplasty. Nevertheless, it remains uncertain whether PCB may reduce the need for reintervention.

01 agosto 2012

JACC. Sirolimus-Eluting Stents for Treatment of Infrapopliteal Arteries Reduce Clinical Event Rate Compared to Bare-Metal Stents. Long-Term Results From a Randomized Trial

Aljoscha Rastan, MD; Klaus Brechtel, MD; Hans Krankenberg, MD; Rainer Zahorsky, MD; Gunnar Tepe, MD; Elias Noory, MD; Uwe Schwarzwälder, MD; Roland Macharzina, MD; Thomas Schwarz, MD; Karlheinz Bürgelin, MD; Sebastian Sixt, MD; Thilo Tübler, MD; Franz-Josef Neumann, MD; Thomas Zeller, MD

Objectives The study investigated the long-term clinical impact of sirolimus-eluting stents (SES) in comparison with bare-metal stents (BMS) in treatment of focal infrapopliteal lesions.

01 septiembre 2012

JACC. Vascular Complications After Transcatheter Aortic Valve Replacement. Insights From the PARTNER (Placement of AoRTic TraNscathetER Valve) Trial

Philippe Généreux, MD; John G. Webb, MD; Lars G. Svensson, MD, PhD; Susheel K. Kodali, MD; Lowell F. Satler, MD; William F. Fearon, MD; Charles J. Davidson, MD; Andrew C. Eisenhauer, MD; Raj R. Makkar, MD; Geoffrey W. Bergman, MB, BS; Vasilis Babaliaros, MD; Joseph E. Bavaria, MD; Omaida C. Velazquez, MD; Mathew R. Williams, MD; Irene Hueter, PhD; Ke Xu, PhD; Martin B. Leon, MD

Objectives This study sought to identify incidence, predictors, and impact of vascular complications (VC) after transfemoral (TF) transcatheter aortic valve replacement (TAVR).

01 julio 2013

DIAGNOSTIC AND INTERVENTIONAL RADIOLOGY. The effect of laser wavelength on postoperative pain score in the endovenous ablation of saphenous vein insufficiency

Enes Duman, Erkan Yıldırım, Tonguç Saba, Mehmet Özülkü, Murat Günday, Gökçen Çoban

PURPOSE: Endovenous laser ablation has replaced surgical methods in the treatment of saphenous insufficiency. The aims of this study were to compare the effectiveness of 1470- and 980-nm wavelength (WL) laser systems, to compare the postoperative complication rates, and to determine the effect of laser WL on postoperative pain scores.

01 julio 2012

STROKE. Multicenter Experience on Eversion Versus Conventional Carotid Endarterectomy in Symptomatic Carotid Artery Stenosis. Observations From the Stent-Protected Angioplasty versus Carotid Endarterectomy (SPACE-1) Trial

Serdar Demirel, MD; Nicolas Attigah, MD; Hans Bruijnen, MD; Peter Ringleb, PhD; Hans-Henning Eckstein, PhD; Gustav Fraedrich, PhD; Dittmar Böckler, PhD on behalf of the SPACE Investigators

Background and Purpose—Carotid endarterectomy (CEA) is beneficial in patients with symptomatic carotid artery stenosis. However, randomized trials have not provided evidence concerning the optimal CEA technique, conventional or eversion.

01 junio 2012

CIRCULATION. Early Results of Fenestrated Endovascular Repair of Juxtarenal Aortic Aneurysms in the United Kingdom

On behalf of the British Society for Endovascular Therapy and the Global Collaborators on Advanced Stent-Graft Techniques for Aneurysm Repair (GLOBALSTAR) Registry

Background—Fenestrated endovascular repair of abdominal aortic aneurysms has been proposed as an alternative to open surgery for juxtarenal and pararenal abdominal aortic aneurysms. At present, the evidence base for this procedure is predominantly limited to single-center or single-operator series. The aim of this study was to present nationwide early results of fenestrated endovascular repair in the United Kingdom.

21 mayo 2013

JACC. Oxidation-Specific Biomarkers and Risk of Peripheral Artery Disease

Monica L. Bertoia, MPH, PhD; Jennifer K. Pai, MHS, ScD; Jun-Hee Lee, MD, PhD; Adam Taleb, MD; Michel M. Joosten, PhD; Murray A. Mittleman, MD, DrPH; Xiaohong Yang, BS; Joseph L. Witztum, MD; Eric B. Rimm, ScD; Sotirios Tsimikas, MD; Kenneth J. Mukamal, MD, MPH

Objectives: The goal of this study was to examine the prospective association between oxidation-specific biomarkers, primarily oxidized phospholipids (OxPL) on apolipoprotein B-100–containing lipoproteins (OxPL/apoB) and lipoprotein (a) [Lp(a)], and risk of peripheral artery disease (PAD). We examined, as secondary analyses, indirect measures of oxidized lipoproteins, including autoantibodies to malondialdehyde-modified low-density lipoprotein (MDA-LDL) and apolipoprotein B-100 immune complexes (ApoB-IC).

01 junio 2013

JACC. Platelet Responsiveness to Clopidogrel Treatment After Peripheral Endovascular Procedures. The PRECLOP Study: Clinical Impact and Optimal Cutoff Value of On-Treatment High Platelet Reactivity

Stavros Spiliopoulos, MD, PhD; Georgios Pastromas, MD; Konstantinos Katsanos, MD, MSc, PhD; Panagiotis Kitrou, MD; Dimitrios Karnabatidis, MD, PhD; Dimitrios Siablis, MD, PhD

Objectives: This study aimed to assess the clinical implications and optimal cutoff value of high platelet reactivity (HPR) in patients receiving clopidogrel for peripheral endovascular procedures.

01 junio 2013

JACC. Sustained Safety and Effectiveness of Paclitaxel-Eluting Stents for Femoropopliteal Lesions. 2-Year Follow-Up From the Zilver PTX Randomized and Single-Arm Clinical Studies

Michael D. Dake, MD; Gary M. Ansel, MD; Michael R. Jaff, DO; Takao Ohki, MD; Richard R. Saxon, MD; H. Bob Smouse, MD; Scott A. Snyder, PhD; Erin E. O Leary, PhD; Gunnar Tepe, MD; Dierk Scheinert, MD; Thomas Zeller, MD

Objectives: A prospective, multinational randomized controlled trial (RCT) and a complementary single-arm study evaluated the 2-year safety and effectiveness of a paclitaxel-coated drug-eluting stent (DES) in patients with superficial femoral artery lesions. The RCT compared the DES with percutaneous transluminal angioplasty (PTA) and provisional bare-metal stent (BMS) placement.

01 junio 2012

CIRCULATION. Long-Term Outcome of Aortic Dissection With Patent False Lumen. Predictive Role of Entry Tear Size and Location

Artur Evangelista, MD, PhD; Armando Salas, MD; Aida Ribera, PhD; Ignacio Ferreira-González, MD, PhD; Hug Cuellar, MD; Victor Pineda, MD; Teresa González-Alujas, MD, PhD; Bart Bijnens, PhD; Gaietà Permanyer-Miralda, MD, PhD; David Garcia-Dorado, MD, PhD

Background—Patent false lumen in aortic dissection has been associated with poor prognosis. We aimed to assess the natural evolution of this condition and predictive factors.

01 mayo 2013

ENDOVASCULAR TODAY. Applying Atherectomy in CLI Patients

By Thomas Zeller, MD, and Lawrence A. Garcia, MD

Critical limb ischemia (CLI) is the most advanced manifestation of peripheral arterial disease and is characterized by persistently recurring rest pain requiring regular analgesia and/or nonhealing ulceration or gangrene of the foot or toes due to impaired blood flow to such an extent that the nutritive requirements of the tissues cannot be met. CLI is generally characterized by multilevel arterial occlusive disease or extensive below-the-knee (BTK) artery involvement and is associated with a high risk for limb and/or tissue loss.1-3

01 mayo 2013

ENDOVASCULAR TODAY. Guidewire Selection for Peripheral Vascular Interventions

By Craig Walker, MD

Guidewires are an integral part of vascular intervention. They are utilized to access target vessels, cross lesions, and deliver definitive interventional therapy. There are many choices in guidewires, as different clinical presentations require different device attributes (Figure 1). Selection of an appropriate guidewire can improve crossing success (particularly in total occlusions), improve device delivery, limit cost, and limit the risk of vascular injury either from the distal wire tip or wire shaft buckling.

01 mayo 2013

ENDOVASCULAR TODAY. Options for Chronic Total Occlusions

By Thomas P. Davis, MD, and James Torey, PA-C

The treatment of chronic total occlusions (CTO) is challenging for the endovascular specialist. Historically, long total occlusions were treated with bypass surgery. Patients with significant comorbidities, however, increasingly need more aggressive percutaneous treatment options. Standard guidewire techniques have been the most frequently used for crossing total occlusions. Treatment failures occur about 20% to 25% of the time;1 the most common reason is failure to cross back into the true lumen beyond the distal cap. Crossing technologies were developed to assist in the treatment of difficult lesions and to increase success rates. Patients with critical limb ischemia depend on successful revascularization, thus making these devices potentially limb saving.

01 mayo 2013

ENDOVASCULAR TODAY. Technique: Ultrasound Guidance for Lower Extremity Interventions

By Jihad A. Mustapha, MD; Matthew Sevensma, DO; Larry J. Diaz-Sandoval, MD; and Fadi Saab, MD

As tibial arterial intervention is becoming more prevalent, noninvasive imaging modalities can increasingly assist endovascular revascularization. Arterial duplex ultrasonography has become an integral part of tibial vessel endovascular interventions in our laboratory. Many procedures are scheduled with an ultrasound technologist present to assist the endovascular specialist in achieving access and delivering therapy.

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