01 abril 2014

CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS. Metabolic syndrome does not impact long-term survival in patients with acute myocardial infarction after successful percutaneous coronary intervention with drug-eluting stents

Ki-Bum Won MD1, Byeong-Keuk Kim MD, PhD2, Hyuk-Jae Chang MD, PhD2, Dong-Ho Shin MD, PhD2, Jung-Sun Kim MD, PhD2, Young-Guk Ko MD2, Donghoon Choi MD, PhD2, Jong-Won Ha MD, PhD2, Myeong-Ki Hong MD, PhD2 andYangsoo Jang MD, PhD2,*

Objective: This study aimed to evaluate long-term survival according to the presence of metabolic syndrome (MS) in patients with acute myocardial infarction (AMI) undergoing successful percutaneous coronary intervention (PCI) with drug-eluting stents (DES).

01 abril 2014

CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS. Outcomes in diabetic patients undergoing primary percutaneous coronary intervention for acute anterior myocardial infarction: Results from the INFUSE-AMI study

Elias A. Sanidas MD, PhD1, Sorin J. Brener MD1,2,*, Akiko Maehara MD1,3, Philippe Généreux MD1,4, Bernhard Witzenbichler MD5, Magdi El-Omar MD6, Martin Fahy MSC1, Roxana Mehran MD1,7, C. Michael Gibson MD8 andGregg W. Stone MD1,3

Objectives: To evaluate the clinical, angiographic, and cardiac magnetic resonance imaging (cMRI) results in patients with and without diabetes mellitus (DM) undergoing primary percutaneous coronary intervention (PCI) for ST-elevation myocardial infarction (STEMI).

18 febrero 2014

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Coronary Hemodynamics. Thermodilution-Derived Coronary Blood Flow Pattern Immediately After Coronary Intervention as a Predictor of Microcirculatory Damage and Midterm Clinical Outcomes in Patients With ST-Segment–Elevation Myocardial Infarction

Masashi Fukunaga, MD, Kenichi Fujii, MD, Daizo Kawasaki, MD, Hisashi Sawada, MD, Koujiro Miki, MD, Hiroto Tamaru, MD, Takahiro Imanaka, MD, Toshihiro Iwasaku, MD, Tsuyoshi Nakata, MD, Masahiko Shibuya, MD, Hirokuni Akahori, MD, Motomaru Masutani, MD, Kaoru Kobayashi, MD, Mitsumasa Ohyanagi, MD and Tohru Masuyama, MD

Background: Despite a sufficient coronary blood flow after primary percutaneous coronary intervention for patients with ST-segment–elevation myocardial infarction; some patients have a poor outcome because of microcirculatory damage. This study evaluates whether the thermodilution-derived coronary blood flow parameters immediately after primary percutaneous coronary intervention predict early microvascular damage and midterm outcomes in patients with ST-segment–elevation myocardial infarction.

25 marzo 2014

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Coronary Hemodynamics. Intracoronary Stem Cell Infusion After Acute Myocardial Infarction. A Meta-Analysis and Update on Clinical Trials

Renate de Jong, MD, Jaco H. Houtgraaf, MD, Sanaz Samiei, BSc, Eric Boersma, PhD and Henricus J. Duckers, MD, PhD

Background: Several cell-based therapies for adjunctive treatment of acute myocardial infarction have been investigated in multiple clinical trials, but the benefits still remain controversial. This meta-analysis aims to evaluate the efficacy of bone marrow–derived mononuclear cell (BMMNC) therapy in patients with acute myocardial infarction, but also explores the effect of newer generations of stem cells.

18 febrero 2014

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Coronary Interventions. Late Adverse Events After Implantation of Sirolimus-Eluting Stent and Bare-Metal Stent. Long-Term (5–7 Years) Follow-Up of the Coronary Revascularization Demonstrating Outcome Study-Kyoto Registry Cohort-2

Masahiro Natsuaki, MD, Takeshi Morimoto, MD, Yutaka Furukawa, MD, Yoshihisa Nakagawa, MD, Kazushige Kadota, MD, Kyohei Yamaji, MD, Kenji Ando, MD, Satoshi Shizuta, MD, Hiroki Shiomi, MD, Tomohisa Tada, MD, Junichi Tazaki, MD, Yoshihiro Kato, MD, Mamoru Hayano, MD, Mitsuru Abe, MD, Takashi Tamura, MD, Manabu Shirotani, MD, Shinji Miki, MD, Mitsuo Matsuda, MD, Mamoru Takahashi, MD, Katsuhisa Ishii, MD, Masaru Tanaka, MD, Takeshi Aoyama, MD, Osamu Doi, MD, Ryuichi Hattori, MD, Masayuki Kato, MD, Satoru Suwa, MD, Akinori Takizawa, MD, Yoshiki Takatsu, MD, Eiji Shinoda, MD, Hiroshi Eizawa, MD, Teruki Takeda, MD, Jong-Dae Lee, MD, Moriaki Inoko, MD, Hisao Ogawa, MD, Shuichi Hamasaki, MD, Minoru Horie, MD, Ryuji Nohara, MD, Hirofumi Kambara, MD, Hisayoshi Fujiwara, MD, Kazuaki Mitsudo, MD, Masakiyo Nobuyoshi, MD, Toru Kita, MD and Takeshi Kimura, MD on behalf of the CREDO-Kyoto PCI/CABG registry cohort-2 investigators

Background: Late adverse events such as very late stent thrombosis (VLST) or late target-lesion revascularization (TLR) after first-generation sirolimus-eluting stents (SES) implantation have not been yet fully characterized at long term in comparison with those after bare-metal stent (BMS) implantation.

15 abril 2014

INTERNATIONAL JOURNAL OF CARDIOLOGY. Novel self-expandable, stent-based transcatheter pulmonic valve: A preclinical animal study

Gi Beom Kim1, Hong-Gook Lim1, Yong Jin Kim1, Eun Young Choi1, Bo Sang Kwon1, Saeromi Jeong1

Background: Because transcatheter implantation of pulmonary valve is indicated for limited-size dysfunctional right ventricular outflow tract only as a balloon-expandable stent, we investigated the feasibility of a large-diameter self-expandable valved stent and the durability of the valve after >6 months.

15 abril 2014

INTERNATIONAL JOURNAL OF CARDIOLOGY. Safety and efficacy of degradable vs. permanent polymer drug-eluting stents: A meta-analysis of 18,395 patients from randomized trials

Yuqing Wang1, Shijian Liu1, Yuanlin Luo, Fangjuan Wang, Huanyun Liu, Lufeng Li, Xiaohui Zhao, Lan Huang

Background: Degradable polymer drug-eluting stents (DP-DES) represent a promising strategy to improve the delayed healing and hypersensitive reaction in the vessel. However, the efficacy and safety of DP-DES vs. permanent polymer drug-eluting stents (PP-DES) are less well defined. The aim of this meta-analysis was to compare the total, short (<30 days), mid (30 days–1 year) and long (>1 year) term outcomes of DP-DES vs. PP-DES.

01 mayo 2014

INTERNATIONAL JOURNAL OF CARDIOLOGY. Prevalence and prognostic implication of restenosis or dilatation at the aortic coarctation repair site assessed by cardiovascular MRI in adult patients late after coarctation repair

S.S.M. Chen1, K. Dimopoulos1, R. Alonso-Gonzalez, E. Liodakis, E. Teijeira-Fernandez, M. Alvarez-Barredo, A. Kempny, G. Diller, A. Uebing, D. Shore, L. Swan, P.J. Kilner, M.A. Gatzoulis, R.H. Mohiaddin

Background: Cardiovascular magnetic resonance (CMR) is ideal for assessing patients with repaired aortic coarctation (CoA). Little is known on the relation between long-term complications of CoA repair as assessed by CMR and clinical outcome. We examined the prevalence of restenosis and dilatation at the repair site and the long-term outcome in patients with repaired CoA.

01 mayo 2014

INTERNATIONAL JOURNAL OF CARDIOLOGY. Bivalirudin in percutaneous coronary intervention: The EUROpean BiValIrudin UtiliSatION in Practice (EUROVISION) Registry

Martial Hamon, Christopher A. Nienaber, Stefano Galli, Kurt Huber, Janusz Lipiecki, Jonathan M. Hill, Nicolas Amabile, Debra Bernstein, Efthymios Deliargyris, Antoine Lafont, Philippe Gabriel Steg

Purpose: The prospective EUROVISION Registry was designed to capture patterns of use and short term outcomes in consecutive patients undergoing PCI with bivalirudin (BIV) in European centres.

15 mayo 2014

INTERNATIONAL JOURNAL OF CARDIOLOGY. Does residual aortic regurgitation after transcatheter aortic valve implantation increase mortality in all patients? The importance of baseline natriuretic peptides

Bogdan Borz1, Eric Durand1, Matthieu Godin1, Christophe Tron1, Alexandre Canville1, Camille Hauville1, Fabrice Bauer1, Alain Cribier1, Hélène Eltchaninoff1

Background: Aortic regurgitation (AR) is an important complication of transcatheter aortic valve implantation (TAVI) and even moderate AR is associated with increased mortality after TAVI. The association with decreased survival is unclear. We aimed to analyse the impact of AR after TAVI as a function of baseline NT-proBNP.

23 enero 2014

EUROPEAN HEART JOURNAL. Biodegradable-polymer drug-eluting stents vs. bare metal stents vs. durable-polymer drug-eluting stents: a systematic review and Bayesian approach network meta-analysis

Si-Hyuck Kang1,†, Kyung Woo Park1,†, Do-Yoon Kang1, Woo-Hyun Lim1, Kyung Taek Park1, Jung-Kyu Han1, Hyun-Jae Kang1, Bon-Kwon Koo1, Byung-Hee Oh1, Young-Bae Park1, David E. Kandzari2, David J. Cohen3, Seung-Sik Hwang4 and Hyo-Soo Kim1,*

Background: The aim of this study was to compare the safety and efficacy of biodegradable-polymer (BP) drug-eluting stents (DES), bare metal stents (BMS), and durable-polymer DES in patients undergoing coronary revascularization, we performed a systematic review and network meta-analysis using a Bayesian framework.

01 abril 2014

CANADIAN JOURNAL OF CARDIOLOGY. Optical Coherence Tomography-Guided Primary Percutaneous Coronary Intervention in ST-Segment Elevation Myocardial Infarction Patients: A Pilot Study

Pavel Červinka, MD, Radim Špaček, MD, Marian Bystroň, MD, Martin Kvašňák, MD, Andrej Kupec, MD, Michaela Červinková, MD, Petr Kala, MD

Background: The objective of our study was to assess whether optical coherence tomography (OCT) guidance could guide intervention to avoid balloon angioplasty and stenting during primary percutaneous coronary intervention.

22 noviembre 2013

CIRCULATION. Epidemiology and Prevention. Impact of Incident Venous Thromboembolism on Risk of Arterial Thrombotic Diseases

Caroline Lind, BSc; Linda E. Flinterman, PhD; Kristin F. Enga, MD, PhD; Marianne T. Severinsen, MD, PhD; Søren R. Kristensen, MD, PhD; Sigrid K. Brækkan, PhD; Ellisiv B. Mathiesen, MD, PhD; Inger Njølstad, MD, PhD; Suzanne C. Cannegieter, MD, PhD; Kim Overvad, MD, PhD; John-Bjarne Hansen, MD, PhD

Background: Growing evidence supports an association between venous thromboembolism (VTE) and arterial thrombotic diseases (ie, myocardial infarction and ischemic stroke). We aimed to study the association between VTE and future arterial events and to determine the population attributable risk of arterial events by VTE in a large prospective cohort recruited from the general population.

26 noviembre 2013

CIRCULATION. Valvular Heart Disease. The Echo Score Revisited. Impact of Incorporating Commissural Morphology and Leaflet Displacement to the Prediction of Outcome for Patients Undergoing Percutaneous Mitral Valvuloplasty

Maria Carmo P. Nunes, MD, PhD; Timothy C. Tan, MD, PhD; Sammy Elmariah, MD, MPH; Rodrigo do Lago, MD; Ronan Margey, MD; Ignacio Cruz-Gonzalez, MD; Hui Zheng, PhD; Mark D. Handschumacher, BS; Ignacio Inglessis, MD; Igor F. Palacios, MD; Arthur E. Weyman, MD; Judy Hung, MD

Background: Current echocardiographic scoring systems for percutaneous mitral valvuloplasty (PMV) have limitations. This study examined new, more quantitative methods for assessing valvular involvement and the combination of parameters that best predicts immediate and long-term outcome after PMV.

03 febrero 2014

CIRCULATION. Stroke. National Assessment of Warfarin Anticoagulation Therapy for Stroke Prevention in Atrial Fibrillation

Jeffrey S. Dlott, MD; Roberta A. George, MS; Xiaohua Huang, MS; Mouneer Odeh, MS; Harvey W. Kaufman, MD; Jack Ansell, MD; Elaine M. Hylek, MD

Background: Anticoagulation control with warfarin, as assessed by the international normalized ratio (INR), is challenging. Time in the therapeutic range has been inversely correlated with major hemorrhage, thrombosis, and mortality. Quest Diagnostics offers standardized INR laboratory testing services to approximately half of US physician practices. To inform national stroke prevention strategies, we evaluated anticoagulation control in office-based community practices.