01 septiembre 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Mechanisms of Atherothrombosis and Vascular Response to Primary Percutaneous Coronary Intervention in Women Versus Men With Acute Myocardial Infarction. Results of the OCTAVIA Study

Giulio Guagliumi, MD∗; Davide Capodanno, MD, PhD†; Francesco Saia, MD‡; Giuseppe Musumeci, MD∗; Giuseppe Tarantini, MD§; Roberto Garbo, MD‖; Gabriele Tumminello, MD¶; Vasile Sirbu, MD∗; Micol Coccato, MD∗; Massimo Fineschi, MD#; Carlo Trani, MD∗∗; Mauro De Benedictis, MD††; Ugo Limbruno, MD‡‡; Leonardo De Luca, MD§§; Giampaolo Niccoli, MD‖‖; Hiram Bezerra, MD¶¶; Elena Ladich, MD##; Marco Costa, MD¶¶; Giuseppe Biondi Zoccai, MD∗∗∗; Renu Virmani, MD##

Objectives: This study sought to assess in vivo sex differences in the pathophysiology of ST-segment elevation myocardial infarction (STEMI) and vascular response to primary percutaneous coronary intervention (PCI).

01 septiembre 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Outcomes After Emergency Percutaneous Coronary Intervention in Patients With Unprotected Left Main Stem Occlusion. The BCIS National Audit of Percutaneous Coronary Intervention 6-Year Experience

Niket Patel, MBBS, BSc∗; Giovanni Luigi De Maria, MD∗; George Kassimis, MD, MSc, PhD∗; Kazem Rahimi, DM, MPH∗; Derrick Bennett, PhD‡; Peter Ludman, MBBChir, MD§; Adrian P. Banning, MBBS, MD∗

Objectives: This study sought to evaluate in-hospital outcomes and 3-year mortality of patients presenting with unprotected left main stem occlusion (ULMSO) treated with primary percutaneous coronary intervention (PPCI).

01 septiembre 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Outcomes of Primary Percutaneous Coronary Intervention in ST-Segment Elevation Myocardial Infarction Patients With Previous Coronary Bypass Surgery

Louis P. Kohl, MD∗; Ross F. Garberich, MS∗; Hannah Yang, BS∗; Scott W. Sharkey, MD∗; M. Nicholas Burke, MD∗; Daniel L. Lips, MD∗; David A. Hildebrandt, RN∗; David M. Larson, MD∗; Timothy D. Henry, MD∗

Objectives: This study sought to determine the contemporary clinical characteristics and outcomes of patients with ST-segment elevation myocardial infarction (STEMI) and previous coronary artery bypass graft (CABG), including those with a saphenous vein graft culprit lesion.

01 septiembre 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Real-Time Assessment of Myocardial Viability in the Catheterization Laboratory Using the Intracoronary Electrograms Recorded by the PTCA Guidewire in Patients With Left Ventricular Dysfunction

Ettore Petrucci, MD∗; Vruyr Balian, MD∗; Andrea Bocchieri, PhD†

Objectives: This study aimed to determine whether the intracoronary electrograms (IC-EGMs) recorded using a standard percutaneous coronary intervention guidewire could provide myocardial viability information.

01 septiembre 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Appropriateness Ratings of Percutaneous Coronary Intervention in Japan and Its Association With the Trend of Noninvasive Testing

Taku Inohara, MD∗; Shun Kohsaka, MD, PhD∗; Hiroaki Miyata, PhD†; Ikuko Ueda, PhD∗; Shiro Ishikawa, MD, PhD‡; Takahiro Ohki, MD, PhD§; Yutaro Nishi, MD‖; Kentaro Hayashida, MD, PhD∗; Yuichiro Maekawa, MD, PhD∗; Akio Kawamura, MD, PhD∗; Takahiro Higashi, MD, PhD¶; Keiichi Fukuda, MD, PhD∗

Objectives: The aim of this study was to evaluate the appropriateness of percutaneous coronary intervention (PCI) in Japan and clarify the association between trends of pre-procedural noninvasive testing and changes in appropriateness ratings.

01 septiembre 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Impact of Balloon Post-Dilation on Clinical Outcomes After Transcatheter Aortic Valve Replacement With the Self-Expanding CoreValve Prosthesis

Marco Barbanti, MD∗; Anna Sonia Petronio, MD‡; Davide Capodanno, MD, PhD∗; Federica Ettori, MD§; Antonio Colombo, MD‖; Francesco Bedogni, MD¶; Federico De Marco, MD#; Marco De Carlo, MD‡; Claudia Fiorina, MD§; Azeem Latib, MD‖; Luca Testa, MD¶; Giuseppe Bruschi, MD#; Arnaldo Poli, MD∗∗; Cristina Giannini, MD‡; Salvatore Curello, MD§; Diego Maffeo, MD§; Carmelo Sgroi, MD∗; Paola Martina, MD∗∗; Simona Gulino, MD∗; Martina Patanè, MD∗; Yohei Ohno, MD∗; Guilherme F. Attizzani, MD∗; Sebastiano Immè, MD∗; Stefano Cannata, MD∗; Alessandra Gentili, MS††; Agnese Rossi, MS‡‡; Corrado Tamburino, MD, PhD∗

Objectives: The aim of this study was to assess the incidence and clinical impact of balloon post-dilation (BPD) after transcatheter aortic valve replacement (TAVR) with the CoreValve prosthesis (Medtronic Inc., Minneapolis, Minnesota).

01 septiembre 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Clinical Impact of Aortic Regurgitation After Transcatheter Aortic Valve Replacement

Miguel Jerez-Valero, MD∗; Marina Urena, MD∗; John G. Webb, MD†; Corrado Tamburino, MD‡; Antonio J. Munoz-Garcia, MD, PhD§; Asim Cheema, MD‖; Antonio E. Dager, MD¶; Vicenç Serra, MD#; Ignacio J. Amat-Santos, MD∗∗; Marco Barbanti, MD†; Sebastiano Immè, MD‡; Juan H. Alonso Briales, MD§; Hatim Al Lawati, MD‖; Luis Miguel Benitez, MD¶; Angela Maria Cucalon, MD¶; Bruno Garcia del Blanco, MD#; Ana Revilla, MD, PhD∗∗; Eric Dumont, MD∗; Henrique Barbosa Ribeiro, MD∗; Luis Nombela-Franco, MD∗; Sébastien Bergeron, MD∗; Philippe Pibarot, PhD∗; Josep Rodés-Cabau, MD∗

Objectives: The aim of this study was to determine the impact of the degree of residual aortic regurgitation (AR) and acuteness of presentation of AR after transcatheter aortic valve replacement (TAVR) on outcomes.

01 septiembre 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Periprocedural Intracardiac Echocardiography for Left Atrial Appendage Closure

Sergio Berti, MD∗; Umberto Paradossi, MD∗; Francesco Meucci, MD†; Giuseppe Trianni, MD∗; Apostolos Tzikas, MD‡; Marco Rezzaghi, MD∗; Miroslava Stolkova, MD†; Cataldo Palmieri, MD∗; Fabio Mori, MD†; Gennaro Santoro, MD†

Objectives: This dual-center study sought to demonstrate the utility and safety of intracardiac echocardiography (ICE) in providing adequate imaging guidance as an alternative to transesophageal echocardiography (TEE) during Amplatzer Cardiac Plug device implantation.

01 septiembre 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Paclitaxel-Coated Balloon Angioplasty Versus Drug-Eluting Stenting for the Treatment of Infrapopliteal Long-Segment Arterial Occlusive Disease

Dimitris Siablis, MD, PhD∗; Panagiotis M. Kitrou, MD, PhD∗; Stavros Spiliopoulos, MD, PhD∗; Konstantinos Katsanos, MSc, MD, PhD†; Dimitris Karnabatidis, MD, PhD∗

Objectives: This study sought to report the results of a prospective randomized controlled trial comparing paclitaxel-coated balloons (PCB) versus drug-eluting stents (DES) in long infrapopliteal lesions.

01 septiembre 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Fluoroscopic Anatomy of Left-Sided Heart Structures for Transcatheter Interventions

Pascal Thériault-Lauzier, PhD∗; Ali Andalib, MD∗; Giuseppe Martucci, MD∗; Darren Mylotte, MD∗; Renzo Cecere, MD†; Rüediger Lange, MD, PhD‡; Didier Tchétché, MD§; Thomas Modine, MD, PhD‖; Nicolas van Mieghem, MD¶; Stephan Windecker, MD#; Jean Buithieu, MD∗; Nicolo Piazza, MD, PhD∗

Abstract: With the introduction of transcatheter structural heart therapies, cardiologists are increasingly aware of the importance of understanding anatomical details of left-sided heart structures. Understanding fluoroscopic cardiac anatomy can facilitate optimal positioning and deployment of prostheses during transcatheter valve repair/replacement, left atrial appendage occlusion, septal defect closure, and paravalvular leak closure. It is possible to use multislice computed tomography to determine optimal fluoroscopic viewing angles for such transcatheter therapies. The purpose of this paper is to describe how optimal fluoroscopic viewing angles of left-sided heart structures can be obtained using computed tomography. Two- and 3-chamber views are described and may become standard in the context of transcatheter structural heart interventions.

07 febrero 2014

EUROPEAN HEART JOURNAL. Lack of association between dual antiplatelet therapy use and stent thrombosis between 1 and 12 months following resolute zotarolimus-eluting stent implantation

Sigmund Silber, Ajay J. Kirtane, Jorge A. Belardi, Minglei Liu, Sandeep Brar, Martin Rothman, Stephan Windecker

Aim: The optimal duration of dual antiplatelet therapy (DAPT) following the use of new generation drug-eluting stents is unknown.

20 mayo 2014

EUROPEAN HEART JOURNAL. A randomized, prospective, intercontinental evaluation of a bioresorbable polymer sirolimus-eluting coronary stent system: the CENTURY II (Clinical Evaluation of New Terumo Drug-Eluting Coronary Stent System in the Treatment of Patients with Coronary Artery Disease) trial

Shigeru Saito, Mariano Valdes-Chavarri, Gert Richardt, Raul Moreno, Andrés Iniguez Romo, Emanuele Barbato, Didier Carrie, Kenji Ando, Bela Merkely, Ran Kornowski, Hélène Eltchaninoff, Stefan James, William Wijns

Aim: The aim of this study was to establish safety and efficacy of a new sirolimus-eluting stent with bioresorbable polymer, Ultimaster (BP-SES). Sirolimus-eluting stent with bioresorbable polymer was compared with everolimus-eluting, permanent polymer, Xience stent (PP-EES) in the frame of a CENTURY II clinical trial designed to make global clinical data compliant with regulatory requirements in Europe and Japan.

01 julio 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Impact of Delay to Reperfusion on Reperfusion Success, Infarct Size, and Clinical Outcomes in Patients With ST-Segment Elevation Myocardial Infarction

Alejandra Guerchicoff, PhD∗; Sorin J. Brener, MD∗; Akiko Maehara, MD∗; Bernhard Witzenbichler, MD‡; Martin Fahy, MSc∗; Ke Xu, PhD∗; Bernard J. Gersh, MD§; Roxana Mehran, MD∗; C. Michael Gibson, MD¶; Gregg W. Stone, MD∗

Objectives: Our aim was to study the impact of delay from symptom onset to first coronary device on infarct size and clinical outcomes at 30 days and 1 year in patients with ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention.

01 julio 2014

JACC: CARDIOVASCULAR INTERVENTIONS. ABSORB Biodegradable Stents Versus Second-Generation Metal Stents

Alessio Mattesini, MD∗; Gioel G. Secco, MD∗; Gianni Dall´Ara, MD∗; Matteo Ghione, MD∗; Juan C. Rama-Merchan, MD∗; Alessandro Lupi, MD‡; Nicola Viceconte, MD∗; Alistair C. Lindsay, MD, PhD∗; Ranil De Silva, MD, PhD∗; Nicolas Foin, PhD§; Toru Naganuma, MD‖; Serafina Valente, MD†; Antonio Colombo, MD, PhD‖; Carlo Di Mario, MD, PhD∗

Objectives: The aim of this study was to compare the acute performance of the PLLA ABSORB bioresorbable vascular scaffold (BVS) (Abbott Vascular, Santa Clara, California) with second-generation metal drug-eluting stents (DES) in complex coronary artery lesions.

01 julio 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Direct Drug-Eluting Stenting to Reduce Stent Restenosis. A Randomized Comparison of Direct Stent Implantation to Conventional Stenting With Pre-Dilation or Provisional Stenting in Elective PCI Patients

Wouter S. Remkes, MD; Samer Somi, MD, PhD; Vincent Roolvink, MD; Saman Rasoul, MD, PhD; Jan Paul Ottervanger, MD, PhD; A.T. Marcel Gosselink, MD, PhD; Jan C.A. Hoorntje, MD, PhD; Jan-Henk E. Dambrink, MD, PhD; Menko-Jan de Boer, MD, PhD; Harry Suryapranata, MD, PhD; Arnoud W.J. van ´t Hof, MD, PhD

Objectives: The aim was to investigate whether a strategy of direct drug-eluting stent (DES) implantation without pre-dilation is associated with a reduced incidence of restenosis compared with CS with pre-dilation or provisional stenting (PS).