01 diciembre 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Scaffold and Edge Vascular Response Following Implantation of Everolimus-Eluting Bioresorbable Vascular Scaffold.A 3-Year Serial Optical Coherence Tomography Study

Yao-Jun Zhang, MD, PhD∗; Javaid Iqbal, PhD∗; Shimpei Nakatani, MD∗; Christos V. Bourantas, MD, PhD∗; Carlos M. Campos, MD∗; Yuki Ishibashi, MD, PhD∗; Yun-Kyeong Cho, MD∗; Susan Veldhof, RN§; Jin Wang§; Yoshinobu Onuma, MD, PhD∗; Hector M. Garcia-Garcia, MD, PhD∗; Dariusz Dudek, MD‖; Robert-Jan van Geuns, MD, PhD∗; Patrick W. Serruys, MD, PhD∗

Objectives: This study sought to investigate the in-scaffold vascular response (SVR) and edge vascular response (EVR) after implantation of an everolimus-eluting bioresorbable scaffold (BRS) using serial optical coherence tomography (OCT) imaging.

01 diciembre 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Outcomes in Patients With Cardiogenic Shock Following Percutaneous Coronary Intervention in the Contemporary Era. An Analysis From the BCIS Database (British Cardiovascular Intervention Society)

Vijay Kunadian, MBBS, MD∗; Weiliang Qiu, PhD‡; Peter Ludman, MD§; Simon Redwood, MD‖; Nick Curzen, PhD¶; Rodney Stables, MD∗∗; Julian Gunn, MD††; Anthony Gershlick, MD‡‡

Objectives: This study sought to determine mortality rates among cardiogenic shock (CGS) patients undergoing percutaneous coronary intervention (PCI) for acute coronary syndrome in the contemporary treatment era and to determine predictors of mortality.

25 noviembre 2014

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Structural Heart Disease. Transcatheter Closure of Large Atrial Septal Defects

Alban-Elouen Baruteau, MD, Jérôme Petit, MD, Virginie Lambert, MD, PhD, Marielle Gouton, MD, Dominique Piot, MD, Philippe Brenot, MD, Claude-Yves Angel, MD, Lucile Houyel, MD, Emmanuel Le Bret, MD, PhD, Régine Roussin, MD, Mohamedou Ly, MD, André Capderou, MD, PhD and Emre Belli, MD

Background: Data are needed on the safety and efficacy of device closure of large atrial septal defects.

11 noviembre 2014

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Structural Heart Disease. Pericardial Endoscopy–Guided Left Atrial Appendage Ligation

Takehiro Kimura, MD, PhD, Seiji Takatsuki, MD, PhD, Shunichiro Miyoshi, MD, PhD, Yoshinori Katsumata, MD, PhD, Takahiko Nishiyama, MD, PhD, Nobuhiro Nishiyama, MD, PhD, Yoko Tanimoto, MD, PhD, Yoshiyasu Aizawa, MD, PhD, Masahiro Jinzaki, MD, PhD and Keiichi Fukuda, MD, PhD

Background: Approaches for closing the left atrial appendage (LAA) have been developed for stroke prevention. However, the prevailing maneuvers require an open-chest surgery, intravascular access, or transseptal puncture. We evaluated the feasibility and safety of pericardial endoscopy-guided LAA ligation in a canine model.

02 diciembre 2014

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Coronary Interventions. Clinical Presentation and Outcomes of Coronary In-Stent Restenosis Across 3-Stent Generations

Marco A. Magalhaes, MD, Sa’ar Minha, MD, Fang Chen, PhD, Rebecca Torguson, MPH, Al Fazir Omar, MD, Joshua P. Loh, MBBS, Ricardo O. Escarcega, MD, Michael J. Lipinski, MD, PhD, Nevin C. Baker, DO, Hironori Kitabata, MD, PhD, Hideaki Ota, MD, William O. Suddath, MD, Lowell F. Satler, MD, Augusto D. Pichard, MD and Ron Waksman, MD

Background: Clinical presentation of bare metal stent in-stent restenosis (ISR) in patients undergoing target lesion revascularization is well characterized and negatively affects on outcomes, whereas the presentation and outcomes of first- and second-generation drug-eluting stents (DESs) remains under-reported.

25 noviembre 2014

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Cardiac Catheterization. Effect of a Real-Time Radiation Monitoring Device on Operator Radiation Exposure During Cardiac Catheterization

Georgios Christopoulos, MD, Aristotelis C. Papayannis, MD, Mohammed Alomar, MD, Anna Kotsia, MD, Tesfaldet T. Michael, MD, Bavana V. Rangan, BDS, MPH, Michele Roesle, RN, BSN, Deborah Shorrock, Lorenza Makke, RCIS, Ronald Layne, BS, Rebecca Grabarkewitz, BS, Donald Haagen, RCIS, Spyros Maragkoudakis, MD, Atif Mohammad, MD, Karan Sarode, MA, Daisha J. Cipher, PhD, Charles E. Chambers, MD, Subhash Banerjee, MD and Emmanouil S. Brilakis, MD, PhD

Background: The Radiation Reduction During Cardiac Catheterization Using Real-Time Monitoring study sought to examine the effect of a radiation detection device that provides real-time operator dose reporting through auditory feedback (Bleeper Sv; Vertec Scientific Ltd; Berkshire, UK) on patient dose and operator exposure during cardiac catheterization.

21 octubre 2014

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Coronary Interventions. Revascularization Decisions in Patients With Stable Angina and Intermediate Lesions

Gabor G. Toth, MD, Balint Toth, MS, Nils P. Johnson, MD, MS, Frederic De Vroey, MD, Luigi Di Serafino, MD, PhD, Stylianos Pyxaras, MD, Dan Rusinaru, MD, Giuseppe Di Gioia, MD, Mariano Pellicano, MD, Emanuele Barbato, MD, PhD, Carlos Van Mieghem, MD, PhD, Guy R. Heyndrickx, MD, PhD, Bernard De Bruyne, MD, PhD and William Wijns, MD, PhD

Background: Fractional flow reserve (FFR) measurement of intermediate coronary stenoses is recommended by guidelines when demonstration of ischemia by noninvasive testing is unavailable. The study aims to evaluate the penetration of this recommendation into current thinking about revascularization strategies for stable coronary artery disease.

04 noviembre 2014

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Coronary Interventions. Stent Coverage and Neointimal Proliferation in Bare Metal Stents Postdilated With a Paclitaxel-Eluting Balloon Versus Everolimus-Eluting Stents

Tudor C. Poerner, MD*, Sylvia Otto, MD*, Johannes Gassdorf, Kristina Nitsche, Florian Janiak, Bruno Scheller, MD, Björn Goebel, MD, Christian Jung, MD and Hans R. Figulla, MD

Background: In this randomized trial, strut coverage and neointimal proliferation of a therapy of bare metal stents (BMSs) postdilated with the paclitaxel drug-eluting balloon (DEB) was compared with everolimus drug-eluting stents (DESs) at 6-month follow-up using optical coherence tomography. We hypothesized sufficient stent coverage at follow-up.

01 diciembre 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Pre-Angioplasty Instantaneous Wave-Free Ratio Pullback Provides Virtual Intervention and Predicts Hemodynamic Outcome for Serial Lesions and Diffuse Coronary Artery Disease

Sukhjinder S. Nijjer, MB ChB∗; Sayan Sen, MBBS, PhD∗; Ricardo Petraco, MD∗; Javier Escaned, MD, PhD†; Mauro Echavarria-Pinto, MD†; Christopher Broyd, MBBS∗; Rasha Al-Lamee, MBBS∗; Nicolas Foin, PhD∗; Rodney A. Foale, MD∗; Iqbal S. Malik, MBBS, PhD∗; Ghada W. Mikhail, MBBS, MD∗; Amarjit S. Sethi, MBBS, PhD∗; Mahmud Al-Bustami, MD∗; Raffi R. Kaprielian, MBBS, MD∗; Masood A. Khan, MB BChir, MA∗; Christopher S. Baker, MBBS, PhD∗; Michael F. Bellamy, MBBS, PhD∗; Alun D. Hughes, PhD‡; Jamil Mayet, MB ChB, MD∗; Darrel P. Francis, MB BChir, MA, MD∗; Carlo Di Mario, MD, PhD§; Justin E.R. Davies, MBBS, PhD∗

Objectives: The aim of this study was to perform hemodynamic mapping of the entire vessel using motorized pullback of a pressure guidewire with continuous instantaneous wave-free ratio (iFR) measurement.

01 diciembre 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Pre-Angioplasty Instantaneous Wave-Free Ratio Pullback and Virtual Revascularization. The Pressure Wire as a Crystal Ball

Jan J. Piek, MD, PhD; Tim P. van de Hoef, MD

Despite technical refinements in intracoronary diagnostic techniques over the past 2 decades, it was not until recently that the monarchy of fractional flow reserve (FFR), the current clinical standard for invasive diagnosis of functional coronary stenosis severity 1, was challenged by a technique that takes advantage of contemporary technology. The instantaneous wave-free ratio (iFR) equals the resting distal coronary pressure–to–aortic pressure ratio during a restricted part of cardiac diastole: the wave-free period (2).

01 diciembre 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Incidence and Imaging Outcomes of Acute Scaffold Disruption and Late Structural Discontinuity After Implantation of the Absorb Everolimus-Eluting Fully Bioresorbable Vascular Scaffold

Yoshinobu Onuma, MD∗; Patrick W. Serruys, MD, PhD∗; Takashi Muramatsu, MD, PhD∗; Shimpei Nakatani, MD∗; Robert-Jan van Geuns, MD, PhD∗; Bernard de Bruyne, MD, PhD†; Dariusz Dudek, MD‡; Evald Christiansen, MD§; Pieter C. Smits, MD, PhD‖; Bernard Chevalier, MD¶; Dougal McClean, MD#; Jacques Koolen, MD, PhD∗∗; Stephan Windecker, MD††; Robert Whitbourn, MD‡‡; Ian Meredith, MD, PhD§§; Hector M. Garcia-Garcia, MD, PhD‖‖; Susan Veldhof, RN¶¶; Richard Rapoza, PhD##; John A. Ormiston, MBChB, PhD∗∗∗

Objectives: This study sought to describe the frequency and clinical impact of acute scaffold disruption and late strut discontinuity of the second-generation Absorb bioresorbable polymeric vascular scaffolds (Absorb BVS, Abbott Vascular, Santa Clara, California) in the ABSORB (A Clinical Evaluation of the Bioabsorbable Everolimus Eluting Coronary Stent System in the Treatment of Patients With De Novo Native Coronary Artery Lesions) cohort B study by optical coherence tomography (OCT) post-procedure and at 6, 12, 24, and 36 months.

01 diciembre 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Outcomes After Percutaneous Coronary Intervention With Stents in Patients Treated With Thoracic External Beam Radiation for Cancer

Jackson J. Liang, DO∗; Terence T. Sio, MD, MS†; Joshua P. Slusser, BS‡; Ryan J. Lennon, MS‡; Robert C. Miller, MD†; Gurpreet Sandhu, MD§; Abhiram Prasad, MD‖

Objectives: The aim of this study was to assess outcomes after percutaneous coronary intervention (PCI) with stents in patients treated with thoracic external beam radiation therapy (EBRT).

01 marzo 2015

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Coronary Interventions. Distal Embolization of Hydrophilic-Coating Material From Coronary Guidewires After Percutaneous Coronary Interventions

Maik J. Grundeken, MD, Xiaofei Li, MD, PhD, C. Eline Kurpershoek, MD, Miranda C. Kramer, MD, PhD, Aryan Vink, MD, PhD, Jan J. Piek, MD, PhD, Jan G.P. Tijssen, PhD, Karel T. Koch, MD, PhD, Joanna J. Wykrzykowska, MD, PhD, Robbert J. de Winter, MD, PhD and Allard C. van der Wal, MD, PhD

Background: Coronary guidewires are indispensable during percutaneous coronary interventions. Nowadays, most guidewires have hydrophilic coatings to improve their trackability, allowing easy lesion passage and facilitating balloon and stent positioning. Recent reports, however, have raised concerns about detachment and subsequent embolization of these hydrophilic coatings.

01 marzo 2015

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Coronary Interventions. Mesh-Covered Embolic Protection Stent Implantation in ST-Segment–Elevation Myocardial Infarction. Final 1-Year Clinical and Angiographic Results From the MGUARD for Acute ST Elevation Reperfusion Trial

Dariusz Dudek, MD, PhD, Artur Dziewierz, MD, PhD, Sorin J. Brener, MD, Alexandre Abizaid, MD, PhD, Béla Merkely, MD, PhD, Ricardo A. Costa, MD, PhD, Eli Bar, BSc, Tomasz Rakowski, MD, PhD, Ran Kornowski, MD, Ovidiu Dressler, MD, Andrea Abizaid, MD, Sigmund Silber, MD, PhD and Gregg W. Stone, MD

Background: The MGuard, a bare metal stent covered with a polymer mesh, was designed to reduce distal embolization during percutaneous coronary intervention in ST-segment–elevation myocardial infarction. In the MGUARD for Acute ST Elevation Reperfusion trial, the primary end point of complete ST-segment resolution was significantly improved with the MGuard compared with control. We evaluated 1-year clinical and angiographic results.

01 marzo 2015

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Coronary Interventions. Comparison of a Novel Biodegradable Polymer Sirolimus-Eluting Stent With a Durable Polymer Everolimus-Eluting Stent. Results of the Randomized BIOFLOW-II Trial

Stephan Windecker, MD, Michael Haude, MD, Franz-Josef Neumann, MD, Karl Stangl, MD, Bernhard Witzenbichler, MD, Ton Slagboom, MD, Manel Sabaté, MD, Javier Goicolea, MD, Paul Barragan, MD, Stéphane Cook, MD, Christophe Piot, MD, Gert Richardt, MD, Béla Merkely, MD, Henrik Schneider, MD, Johannes Bilger, MD, Paul Erne, MD, Ron Waksman, MD, Serge Zaugg, MSc, Peter Jüni, MD and Thierry Lefèvre, MD

Background: Biodegradable polymers for release of antiproliferative drugs from drug-eluting stents aim to improve vascular healing. We assessed noninferiority of a novel ultrathin strut drug-eluting stent releasing sirolimus from a biodegradable polymer (Orsiro, O-SES) compared with the durable polymer Xience Prime everolimus-eluting stent (X-EES) in terms of the primary end point in-stent late lumen loss at 9 months.