01 marzo 2016

CANADIAN JOURNAL OF CARDIOLOGY. Differences in Vessel Healing Between Sirolimus- and Everolimus-Eluting Stent Implantation for Bifurcation Lesions: The J-REVERSE Optical Coherence Tomography Substudy

Daisuke Terashita, MD, Hiromasa Otake, MD, PhD, Toshiro Shinke, MD, PhD, Yoshinobu Murasato, MD, PhD, Yoshihisa Kinoshita, MD, Masahiro Yamawaki, MD, PhD, Yoshihiro Takeda, MD, PhD, Kenichi Fujii, MD, PhD, Shin-ichiro Yamada, MD, PhD, Yoshihisa Shimada, MD, PhD, Takehiro Yamashita, MD, PhD, Kazuhiko Yumoto, MD, PhD, Ken-ichi Hirata, MD, PhD

Background: We aimed to clarify the differences in vessel healing after stenting of bifurcation lesions using sirolimus-eluting stents (SESs) or everolimus-eluting stents (EESs).

01 febrero 2016

CANADIAN JOURNAL OF CARDIOLOGY. Psoas Muscle Area and All-Cause Mortality After Transcatheter Aortic Valve Replacement: The Montreal-Munich Study

Samuel Mamane, MD∗, Louis Mullie, MD∗, Nicolo Piazza, MD, PhD, Giuseppe Martucci, MD, José Morais, MD, Antonio Vigano, MD, Mark Levental, MD, Kristoff Nelson, MD, Ruediger Lange, MD, Jonathan Afilalo, MD, MSc

Background: Psoas muscle area (PMA) is a novel measure of frailty that can be efficiently measured from computed tomography images to help predict risk in older adults referred for transcatheter aortic valve replacement (TAVR). The objective of this study was to determine if PMA would be incrementally predictive of mortality and morbidity after TAVR.

01 febrero 2016

CANADIAN JOURNAL OF CARDIOLOGY. Effect of Baseline Thrombocytopenia on Ischemic Outcomes in Patients With Acute Coronary Syndromes Who Undergo Percutaneous Coronary Intervention

Mayank Yadav, MD, Philippe Généreux, MD, Gennaro Giustino, MD, Mahesh V. Madhavan, BA, Sorin J. Brener, MD, Gary Mintz, MD, Adriano Caixeta, MD, PhD, Ke Xu, PhD, Roxana Mehran, MD, Gregg W. Stone, MD

Background: Acquired thrombocytopenia (TP) has been associated with short- and long-term adverse outcomes after percutaneous coronary intervention (PCI), but the role of baseline TP is less well defined. We sought to evaluate the effect of TP on long-term adverse outcomes in patients with acute coronary syndromes (ACS) who undergo PCI.

01 febrero 2016

CANADIAN JOURNAL OF CARDIOLOGY. Three-Dimensional Optical Coherence Tomographic Analysis of Eccentric Morphology of the Jailed Side-Branch Ostium in Coronary Bifurcation Lesions

Sungsoo Cho, MD, Jung-Sun Kim, MD, Jinyong Ha, PhD, Dong-Ho Shin, MD, MPH, Byeong-Keuk Kim, MD, Young-Guk Ko, MD, Donghoon Choi, MD, Yangsoo Jang, MD, Myeong-Ki Hong, MD

Background: The severity of angiographic diameter stenosis of the jailed side-branch ostium is usually overestimated over the 3-D optical coherence tomography (OCT)-measured actual stenosis. Using 3-D OCT, morphologic changes in the jailed side-branch ostium were evaluated before and after a single stent crossover at coronary bifurcation lesions.

01 febrero 2016

CANADIAN JOURNAL OF CARDIOLOGY. Utility of the Logistic Clinical Syntax Score in the Prediction of Contrast-Induced Nephropathy After Primary Percutaneous Coronary Intervention

Derya Ozturk, MD, Omer Celik, MD, Mehmet Erturk, MD, Ali Kemal Kalkan, MD, Fatih Uzun, MD, Ibrahim Faruk Akturk, MD, Fatih Akin, MD, Aydin Yildirim, MD

Background: The Logistic Clinical Syntax Score (log CSS) is a combined risk scoring system that includes clinical and anatomic parameters; it has been found to be effective for the prediction of mortality in patients with ST-elevation myocardial infarction (STEMI). The aim of the present study was to assess whether the log CSS was associated with the development of contrast-induced nephropathy (CIN) in patients who underwent primary percutaneous coronary intervention (pPCI).

01 diciembre 2015

CANADIAN JOURNAL OF CARDIOLOGY. Transfemoral vs Non-transfemoral Access for Transcatheter Aortic Valve Implantation: A Systematic Review and Meta-analysis

Jaya Chandrasekhar, MBBS, Benjamin Hibbert, MD, PhD, Marc Ruel, MD, Buu-Khanh Lam, MD, Marino Labinaz, MD, Christopher Glover, MD

Background: Transcatheter aortic valve implantation (TAVI) is the definitive therapy for high-risk patients with severe aortic stenosis. The aim of this study was to determine the effect of non-transfemoral access on clinical outcomes in TAVI.

01 diciembre 2015

CANADIAN JOURNAL OF CARDIOLOGY. Antecubital vs Femoral Venous Access for Right Heart Catheterization: Benefits of a Flashback

Vincent Roule, MD, Sabri Ailem, MD, Damien Legallois, MD, Ziad Dahdouh, MD, Thérèse Lognoné, MD, Emmanuel Bergot, MD, PhD, Gilles Grollier, MD, Paul Milliez, MD, PhD, Rémi Sabatier, MD, Farzin Beygui, MD, PhD

Background: Although rare, complications of right heart catheterization (RHC) are usually related to the access site. Antecubital venous access for RHC allows immediate ambulation and may reduce access-site complications, but data on this approach are scarce.

01 diciembre 2015

CANADIAN JOURNAL OF CARDIOLOGY. Transcatheter Left Atrial Appendage Closure Using Intracardiac Echocardiographic Guidance From the Left Atrium

Jean-Bernard Masson, MD, FRCPC, Rémi Kouz, MD, MSc, Mounir Riahi, MD, Hien Kiem Nguyen Thanh, MD, Jeannot Potvin, MD, FRCPC, Charbel Naim, MD, Reda Salem, MD, FRCPC, Jean-Marc Raymond, MD, FRCPC

Background: Most commonly, left atrial appendage (LAA) occlusion procedures are performed using transesophageal echocardiography (TEE) guidance and general anaesthesia. Intracardiac echocardiography (ICE) offers potential advantages over TEE, however, ICE-guided LAA occlusion experience is limited and has been typically performed from a right-sided location where LAA visualization might be suboptimal. We sought to evaluate the efficacy and safety of percutaneous LAA occlusion using ICE guidance performed from the left atrium.

15 marzo 2016

INTERNATIONAL JOURNAL OF CARDIOLOGY. Impact of chronic kidney disease on left atrial appendage occlusion for stroke prevention in patients with atrial fibrillation

Joelle Kefer, Apostolos Tzikas, Xavier Freixa, Samera Shakir, Sameer Gafoor, Jens Erik Nielsen-Kudsk, Sergio Berti, Gennaro Santoro, Adel Aminian, Ulf Landmesser, Fabian Nietlispach, Reda Ibrahim, Paolo Luciano Danna, Edouard Benit, Werner Budts, Francis Stammen, Tom De Potter, Tobias Tichelbäcker, Steffen Gloekler, Prapa Kanagaratnam, Marco Costa, Ignacio Cruz-Gonzalez, Horst Sievert, Wolfgang Schillinger, Jai-Wun Park, Bernhard Meier, Heyder Omran

Background: Left atrial appendage occlusion (LAAO) using the Amplatzer cardiac plug (ACP) is a preventive treatment of atrial fibrillation related thromboembolism.

15 marzo 2016

INTERNATIONAL JOURNAL OF CARDIOLOGY. Impact of gender on infarct size, ST-segment resolution, myocardial blush and clinical outcomes after primary stenting for acute myocardial infarction: Substudy from the EMERALD trial

Vivian G. Ng, Ken Mori, Ricardo A. Costa, Mitra Kish, Roxana Mehran, Hidenori Urata, Keijiro Saku, Gregg W. Stone, Alexandra J. Lansky

Background: Women with AMI may have worse outcomes than men. However, it is unclear if this is related to differences in treatment, treatment effect or gender specific factors. We sought to determine whether primary percutaneous intervention (PCI) has a differential impact on infarct size, myocardial perfusion and ST segment resolution in men and women with acute myocardial infarction (AMI).

15 marzo 2016

INTERNATIONAL JOURNAL OF CARDIOLOGY. Optimal duration of dual antiplatelet therapy after second-generation drug-eluting stent implantation in patients with diabetes: The SECURITY (Second-Generation Drug-Eluting Stent Implantation Followed By Six- Versus Twelve-Month Dual Antiplatelet Therapy)-diabetes substudy

Giuseppe Tarantini, Luca Nai Fovino, Paola Tellaroli, Alaide Chieffo, Alberto Barioli, Alberto Menozzi, Arian Frasheri, Roberto Garbo, Monica Masotti-Centol, Neus Salvatella, Juan Francisco Oteo Dominguez, Luigi Steffanon, Patrizia Presbitero, Edoardo Pucci, Chiara Fraccaro, Josepa Mauri, Gennaro Giustino, Gennaro Sardella, Antonio Colombo

Background/Objectives: The randomized SECURITY (Second-Generation Drug-Eluting Stent Implantation Followed by Six- Versus Twelve-Month Dual Antiplatelet Therapy) trial showed the non-inferiority of 6 vs. 12-month DAPT after percutaneous coronary intervention (PCI) with second-generation DES in a low-risk population. Nevertheless, diabetes mellitus (DM) remained a major predictor of adverse cardiovascular events. We aimed to assess the interaction between DAPT duration and outcome in DM patients.

15 abril 2016

INTERNATIONAL JOURNAL OF CARDIOLOGY. Efficacy and safety of bivalirudin versus heparin in patients undergoing percutaneous coronary intervention: A meta-analysis of randomized controlled trials

Shuo Zhang, Weihua Gao, Haixia Li, Meijuan Zou, Sihao Sun, Yijie Ba, Yang Liu, Gang Cheng

Background: The efficacy and safety of bivalirudin versus heparin in patients undergoing percutaneous coronary intervention (PCI) remains controversial in to date. Our meta-analysis was undertaken to evaluate the efficacy and safety of bivalirudin compared with heparin in patients undergoing PCI.

15 abril 2016

INTERNATIONAL JOURNAL OF CARDIOLOGY. Real-world cost effectiveness of MitraClip combined with Medical Therapy Versus Medical therapy alone in patients with moderate or severe mitral regurgitation

Patrizio Armeni, Paola R. Boscolo, Rosanna Tarricone, Davide Capodanno, Aldo P. Maggioni, Carmelo Grasso, Corrado Tamburino, Francesco Maisano

Background: We evaluated the real-world cost-effectiveness of the MitraClip system (Abbott Vascular Inc., Menlo Park, CA) plus medical therapy for patients with moderate/severe mitral regurgitation, as compared with medical therapy (MT) alone.

01 abril 2016

INTERNATIONAL JOURNAL OF CARDIOLOGY. Bioresorbable Scaffold vs. Second Generation Drug Eluting Stent in Long Coronary Lesions requiring Overlap: A Propensity-Matched Comparison (the UNDERDOGS study)

Simone Biscaglia,email, Fabrizio Ugo1, Alfonso Ielasi1, Gioel Gabrio Secco1, Alessandro Durante1, Fabrizio D´Ascenzo1, Enrico Cerrato1, Mohammed Balghith1, Giampaolo Pasquetto1, Carlo Penzo1, Massimo Fineschi1, Francesco Bonechi1, Christian Templin1, Mila Menozzi1, Matteo Aquilina1, Andrea Rognoni1, Piera Capasso1, Carlo Di Mario1, Salvatore Brugaletta1, Gianluca Campo1

Background: Randomized clinical trials on bioresorbable scaffolds (BRS) enrolled patients with simple coronary lesions. The present study was sought to give preliminary findings about safety of BRS implantation in overlap in long coronary lesions.

01 abril 2016

INTERNATIONAL JOURNAL OF CARDIOLOGY. Anticoagulant therapy after venous thromboembolism and 10-year mortality

Torben Bjerregaard Larsen1, Gregory Y.H. Lip1, Anders Gorst-Rasmussen

Background: Pulmonary embolism (PE) is associated with a higher long-term mortality than deep vein thrombosis (DVT). This association may be related to inadequate antithrombotic therapy.