01 julio 2013

JACC. Percutaneous Left Atrial Appendage Closure With the AMPLATZER Cardiac Plug Device in Patients With Nonvalvular Atrial Fibrillation and Contraindications to Anticoagulation Therapy

Marina Urena, MD; Josep Rodés-Cabau, MD; Xavier Freixa, MD; Jacqueline Saw, MD; John G. Webb, MD; Mélanie Freeman, MD; Eric Horlick, MD; Mark Osten, MD; Albert Chan, MD; Jean-Francois Marquis, MD; Jean Champagne, MD; Réda Ibrahim, MD

Objectives: The aim of this study was to evaluate the results associated with left atrial appendage closure (LAAC) with the AMPLATZER Cardiac Plug (ACP) (St. Jude Medical, Minneapolis, Minnesota) in patients with nonvalvular atrial fibrillation and absolute contraindications to anticoagulation therapy.

01 julio 2013

JACC: CARDIOVASCULAR INTERVENTIONS. Zotarolimus- and Paclitaxel-Eluting Stents in an All-Comer Population in China. The RESOLUTE China Randomized Controlled Trial

Bo Xu, MBBS; Yuejin Yang, MD; Zuyi Yuan, MD; Zhimin Du, MD; S. Chiu Wong, MD; Philippe Généreux, MD; Shuzheng LU, MD

Objectives: This study sought to compare clinical outcomes and angiographic findings using the Resolute zotarolimus-eluting stent (R-ZES) (Medtronic, Santa Rosa, California) versus the Taxus Liberte paclitaxel-eluting stent (PES) (Boston Scientific, Natick, Massachusetts) in an all-comer Chinese population.

01 agosto 2013

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Comparison of Manual Thrombus Aspiration With Rheolytic Thrombectomy in Acute Myocardial Infarction

Guido Parodi, MD, PhD, Renato Valenti, MD, Angela Migliorini, MD, Akiko Maehara, MD, Ruben Vergara, MD, Nazario Carrabba, MD, Gary S. Mintz, MD and David Antoniucci, MD

Background—Manual thrombus aspiration (MTA) is completely ineffective in 30% of cases, and the high profiles of the catheters prevent their use in tortuous and calcified vessels. The rheolytic thrombectomy (RT) device has the potential for improved thrombus removal in acute myocardial infarction as compared with MTA. No data exist on the comparison between the 2 techniques.

01 julio 2013

JACC. Percutaneous Left Atrial Appendage Suture Ligation Using the LARIAT Device in Patients With Atrial Fibrillation. Initial Clinical Experience

Krzysztof Bartus, MD, PhD; Frederick T. Han, MD; Jacek Bednarek, MD, PhD; Jacek Myc, MD, PhD; Boguslaw Kapelak, MD, PhD; Jerzy Sadowski, MD, PhD; Jacek Lelakowski, MD, PhD; Stanislaw Bartus, MD, PhD; Steven J. Yakubov, MD; Randall J. Lee, MD, PhD

Objectives: The purpose of the study was to determine the efficacy and safety of left atrial appendage (LAA) closure via a percutaneous LAA ligation approach.

01 agosto 2013

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Residual Ischemia After Revascularization in Multivessel Coronary Artery Disease. Insights From Measurement of Absolute Myocardial Blood Flow Using Magnetic Resonance Imaging Compared With Angiographic Assessment

Jayanth R. Arnold, BMBCh, MA, MRCP, DPhil, Theodoros D. Karamitsos, MD, PhD, William J. van Gaal, MD, Luca Testa, MD, PhD, Jane M. Francis, DCRR, DNM, Paul Bhamra-Ariza, MBBS, BSc, MRCP, Ali Ali, MBBS, MRCPI, FCPS, Joseph B. Selvanayagam, MBBS, DPhil, FRACP, FESC, Steve Westaby, MBBS, FRCS, PhD, FESC, FECTS, Rana Sayeed, MBBS, FRCS, Michael Jerosch-Herold, PhD, Stefan Neubauer, MD, FRCP, FMedSci and Adrian P. Banning, MBBS, MD, FRCP, FESC

Background—Revascularization strategies for multivessel coronary artery disease include percutaneous coronary intervention and coronary artery bypass grafting. In this study, we compared the completeness of revascularization as assessed by coronary angiography and by quantitative serial perfusion imaging using cardiovascular magnetic resonance.

01 julio 2013

JACC. Long-Term Results After Simple Versus Complex Stenting of Coronary Artery Bifurcation Lesions. Nordic Bifurcation Study 5-Year Follow-Up Results

Michael Maeng, MD; Niels R. Holm, MD; Andrejs Erglis, MD; Indulis Kumsars, MD; Matti Niemelä, MD; Kari Kervinen, MD; Jan S. Jensen, MD; Anders Galløe, MD; Terje K. Steigen, MD; Rune Wiseth, MD; Inga Narbute, MD; Pål Gunnes, MD; Jan Mannsverk, MD; Oliver Meyerdierks, MD; Svein Rotevatn, MD; Kjell Nikus, MD; Saila Vikman, MD; Jan Ravkilde, MD; Stefan James, MD; Jens Aarøe, MD; Antti Ylitalo, MD; Steffen Helqvist, MD; Iwar Sjögren, MD; Per Thayssen, MD; Kari Virtanen, MD; Mikko Puhakka, MD; Juhani Airaksinen, MD; Evald H. Christiansen, MD; Jens F. Lassen, MD; Leif Thuesen, MD

Objectives: This study sought to report the 5-year follow-up results of the Nordic Bifurcation Study.

01 julio 2013

JACC: CARDIVASCULAR INTERVENTIONS. Comparison of 5-Year Outcomes in Patients With and Without Unprotected Left Main Coronary Artery Disease After Treatment With Sirolimus-Eluting StentsInsights From the j-Cypher Registry

Mamoru Toyofuku, MD; Takeshi Kimura, MD; Takeshi Morimoto, MD; Yasuhiko Hayashi, MD; Nobuo Shiode, MD; Hideo Nishikawa, MD; Koichi Nakao, MD; Kinya Shirota, MD; Kazuya Kawai, MD; Yoshikazu Hiasa, MD; Kazushige Kadota, MD; Yoichi Nozaki, MD; Takaaki Isshiki, MD; Takahito Sone, MD; Kazuaki Mitsudo, MD

Objectives: This study assessed 5-year outcomes after implantation of sirolimus-eluting stents (SES) for unprotected left main coronary artery (ULMCA) disease in comparison with that for non-left main disease.

01 agosto 2013

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Remote Ischemic Preconditioning Improves Outcome at 6 Years After Elective Percutaneous Coronary Intervention. The CRISP Stent Trial Long-term Follow-up

William R. Davies, PhD, MRCP, Adam J. Brown, MRCP, William Watson, MRCP, Liam M. McCormick, MRCP, Nick E.J. West, MD, FRCP, David P. Dutka, MD, FRCP and Stephen P. Hoole, MA, DM, MRCP

Background—Postprocedural myocardial infarction (type 4a) has been shown to be an adverse prognostic indicator after elective percutaneous coronary intervention (PCI). The Cardiac Remote Ischemic Preconditioning in Coronary Stenting (CRISP Stent) study demonstrated that remote ischemic preconditioning reduced procedural symptoms, ECG ST-segment deviation, and cardiac troponin I release after elective PCI and reduced the major adverse cardiac and cerebral event (MACCE) rate at 6 months. We were interested to confirm if this early benefit in MACCE rate in the remote ischemic preconditioning group was sustained long-term.

01 octubre 2012

CIRCULATION. Clinical and Angiographic Risk Stratification and Differential Impact on Treatment Outcomes in the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) Trial

Maria Mori Brooks, PhD; Bernard R. Chaitman, MD; Richard W. Nesto, MD; Regina M. Hardison, MS; Frederick Feit, MD; Bernard J. Gersh, MD, PhD; Ronald J. Krone, MD; Edward Y. Sako, MD; William J. Rogers, MD; Alan J. Garber, MD; Spencer B. King III, MD; Charles J. Davidson, MD; Fumiaki Ikeno, MD; Robert L. Frye, MD for the BARI 2D Study Group

Background—The Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) trial assigned patients with type 2 diabetes mellitus to prompt coronary revascularization plus intensive medical therapy versus intensive medical therapy alone and reported no significant difference in mortality. Among patients selected for coronary artery bypass graft surgery, prompt coronary revascularization was associated with a significant reduction in death/myocardial infarction/stroke compared with intensive medical therapy. We hypothesized that clinical and angiographic risk stratification would affect the effectiveness of the treatments overall and within revascularization strata.

01 julio 2013

JACC. Patent Foramen Ovale, Subclinical Cerebrovascular Disease, and Ischemic Stroke in a Population-Based Cohort

Marco R. Di Tullio, MD; Zhezhen Jin, PhD; Cesare Russo, MD; Mitchell S.V. Elkind, MD, MS; Tatjana Rundek, MD, PhD; Mitsuhiro Yoshita, MD, PhD; Charles DeCarli, MD; Clinton B. Wright, MD, MS; Shunichi Homma, MD; Ralph L. Sacco, MD, MS

Objectives: The purpose of this study was to evaluate the relationship between patent foramen ovale (PFO), ischemic stroke, and subclinical cerebrovascular disease in the general population.

01 agosto 2013

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Transulnar Compared With Transradial Artery Approach as a Default Strategy for Coronary Procedures. A Randomized Trial The Transulnar or Transradial Instead of Coronary Transfemoral Angiographies Study (The AURA of ARTEMIS Study)

George Hahalis, MD, PhD, Grigorios Tsigkas, MD, Ioanna Xanthopoulou, MD, Spyridon Deftereos, MD, Antonios Ziakas, MD, PhD, Konstantinos Raisakis, MD, Christos Pappas, MD, Aggelos Sourgounis, MD, Nikos Grapsas, MD, Periklis Davlouros, MD, PhD, Anastasia Galati, MD, Theodora-Eleni Plakomyti, MD, Panagiota Mylona, MD, Ioannis Styliadis, MD, PhD, Vlassis Pyrgakis, MD, FESC and Dimitrios Alexopoulos, MD, PhD, FESC

Background—The ulnar artery is rarely selected for coronary angiography or percutaneous coronary intervention despite the expanding use of the transradial approach. We aimed to establish noninferiority of a default transulnar relative to transradial approach in terms of feasibility and safety.

01 julio 2013

JACC: CARDIVASCULAR INTERVENTIONS. Late Thrombosis After Double Versus Single Drug-Eluting Stent in the Treatment of Coronary Bifurcations. A Meta-Analysis of Randomized and Observational Studies

Marco Zimarino, MD, PhD; Alessandro Corazzini, MD; Fabrizio Ricci, MD; Marta Di Nicola, PhD; Raffaele De Caterina, MD, PhD

Objectives: This study sought to hypothesize that the higher risk of myocardial infarction (MI) documented after a routine double drug-eluting stent (DES) strategy (DDS) compared with a single DES strategy (SDS) with provisional stenting in percutaneous coronary interventions (PCI) of bifurcation lesions is driven by an increased rate of DES thrombosis.

01 julio 2013

JACC: CARDIVASCULAR INTERVENTIONS. Influence of Arterial Access Site Selection on Outcomes in Primary Percutaneous Coronary Intervention. Are the Results of Randomized Trials Achievable in Clinical Practice?

Mamas A. Mamas, BM BCh, DPhil; Karim Ratib, MB BS; Helen Routledge, MD; Ludwig Neyses, MD; Douglas G. Fraser, MB BChir, MD; Mark de Belder, MA, MD; Peter F. Ludman, MA, MD; Jim Nolan, MD

Objectives This study sought to investigate the influence of access site utilization on mortality, major adverse cardiac and cardiovascular events (MACCE), bleeding, and vascular complications in a large number of patients treated by primary percutaneous coronary intervention (PPCI) in the United Kingdom over a 5-year period, through analysis of the British Cardiovascular Intervention Society database.

01 julio 2013

JACC: CARDIVASCULAR INTERVENTIONS. Pulmonary Edema Predictive Scoring Index (PEPSI), a New Index to Predict Risk of Reperfusion Pulmonary Edema and Improvement of Hemodynamics in Percutaneous Transluminal Pulmonary Angioplasty

Takumi Inami, MD; Masaharu Kataoka, MD; Nobuhiko Shimura, MD; Haruhisa Ishiguro, MD; Ryoji Yanagisawa, MD; Hiroki Taguchi, MD; Keiichi Fukuda, MD; Hideaki Yoshino, MD; Toru Satoh, MD

Objectives: This study sought to identify useful predictors for hemodynamic improvement and risk of reperfusion pulmonary edema (RPE), a major complication of this procedure.

01 septiembre 2013

RADIOLOGY. Ischemic Stroke: Measurement of Intracranial Artery Calcifications Can Improve Prediction of Asymptomatic Coronary Artery Disease

Sung Soo Ahn, MD, Hyo Suk Nam, MD, Ji Hoe Heo, MD, Young Dae Kim, MD, Seung-Koo Lee, MD, Kyung Hwa Han, MS, Byoung Wook Choi, MD and Eung Yeop Kim, MD

Purpose: To examine the associations between intracranial artery calcifications (IACs) and coronary artery calcifications (CACs) in patients with ischemic stroke and to assess the predictive value of IAC for asymptomatic coronary artery disease (CAD).