01 octubre 2013

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Outcomes With Various Drug-Eluting or Bare Metal Stents in Patients With ST-Segment–Elevation Myocardial Infarction. A Mixed Treatment Comparison Analysis of Trial Level Data From 34 068 Patient-Years of Follow-up From Randomized Trials

Sripal Bangalore, MD, MHA, Nicholas Amoroso, MD, Mario Fusaro, MD, Sunil Kumar, MD and Frederick Feit, MD

Background—The efficacy and safety of drug-eluting stents (DES) in patients with ST-segment–elevation myocardial infarction (STEMI) is controversial. Consequently, DES implantation has a class IIa indication in the American College of Cardiology/American Heart Association and the European Society of Cardiology STEMI guidelines.

01 julio 2013

JACC. Determinants and Outcomes of Acute Transcatheter Valve-in-Valve Therapy or Embolization. A Study of Multiple Valve Implants in the U.S. PARTNER Trial (Placement of AoRTic TraNscathetER Valve Trial Edwards SAPIEN Transcatheter Heart Valve)

Raj R. Makkar, MD; Hasan Jilaihawi, MD; Tarun Chakravarty, MD; Gregory P. Fontana, MD; Samir Kapadia, MD; Vasilis Babaliaros, MD; Wen Cheng, MD; Vinod H. Thourani, MD; Joseph Bavaria, MD; Lars Svensson, MD; Susheel Kodali, MD; Takahiro Shiota, MD; Robert Siegel, MD; E. Murat Tuzcu, MD; Ke Xu, PhD; Rebecca T. Hahn, MD; Howard C. Herrmann, MD; Mark Reisman, MD; Brian Whisenant, MD; Scott Lim, MD; Nirat Beohar, MD; Michael Mack, MD; Paul Teirstein, MD; Charanjit Rihal, MD, MBA; Pamela S. Douglas, MD; Eugene Blackstone, MD; Augusto Pichard, MD; John G. Webb, MD; Martin B. Leon, MD

Objectives: This study investigated the determinants and outcomes of acute insertion of a second transcatheter prosthetic valve (TV) within the first (TV-in-TV) or transcatheter valve embolization (TVE) after transcatheter aortic valve replacement (TAVR).

01 julio 2013

JACC. Use of Stress Testing and Diagnostic Catheterization After Coronary Stenting. Association of Site-Level Patterns With Patient Characteristics and Outcomes in 247,052 Medicare Beneficiaries

Bimal R. Shah, MD, MBA; Lisa A. McCoy, MS; Jerome J. Federspiel, AB; Daniel Mudrick, MD, MPH; Patricia A. Cowper, PhD; Frederick A. Masoudi, MD, MSPH; Barbara L. Lytle, MS; Cynthia L. Green, PhD; Pamela S. Douglas, MD

Objectives: The aim of this study was to determine diagnostic testing patterns after percutaneous coronary intervention (PCI).

01 julio 2013

JACC. Same-Day Discharge After Percutaneous Coronary Intervention. A Meta-Analysis

Kimberly M. Brayton, MD, JD; Vishal G. Patel, MD; Christopher Stave, MLS; James A. de Lemos, MD; Dharam J. Kumbhani, MD, SM

Objectives: This study sought to assess the safety of same-day discharge in patients undergoing percutaneous coronary intervention (PCI).

01 agosto 2013

JACC: CARDIOVASCULAR INTERVENTIONS. Radial Versus Femoral Access for Primary Percutaneous Interventions in ST-Segment Elevation Myocardial Infarction PatientsA Meta-Analysis of Randomized Controlled Trials

Wassef Karrowni, MD; Ankur Vyas, MD; Bria Giacomino, DO; Marin Schweizer, PhD; Amy Blevins, MALS; Saket Girotra, MD, SM; Phillip A. Horwitz, MD

Objectives This study sought to determine the safety and efficacy of radial access compared with femoral access for primary percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI).

01 octubre 2013

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Outcomes After Primary Transcatheter Therapy in Infants and Young Children With Severe Bilateral Peripheral Pulmonary Artery Stenosis

Jonathan W. Cunningham, BA, Doff B. McElhinney, MD, Kimberlee Gauvreau, DSc, Lisa Bergersen, MD, Ronald V. Lacro, MD, Audrey C. Marshall, MD, Leslie Smoot, MD and James E. Lock, MD

Background—Angioplasty and stent implantation have become accepted therapies for isolated peripheral pulmonary stenosis, and have been shown to increase vessel diameter and reduce right ventricular (RV) pressure acutely in patients with pulmonary artery (PA) stenosis. The purpose of this study was to assess long-term outcomes after primary transcatheter therapy for peripheral pulmonary stenosis.

01 octubre 2013

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Prognostic Value of Access and Non–Access Sites Bleeding After Percutaneous Coronary Intervention

Gjin Ndrepepa, MD, Franz-Josef Neumann, MD, Gert Richardt, MD, Stefanie Schulz, MD, Ralph Tölg, MD, Kiril M. Stoyanov, Michael Gick, MD, Tareq Ibrahim, MD, Katrin Anette Fiedler, MD, Peter B. Berger, MD, Karl-Ludwig Laugwitz, MD and Adnan Kastrati, MD

Background—Little is known about the impact of bleeding site on mortality after percutaneous coronary intervention. The aim of this study was to assess the impact of access and non–access site bleeding within 30 days after percutaneous coronary intervention on mortality.

01 julio 2013

JACC. Sirolimus-Eluting Stents for Treatment of Infrapopliteal Arteries Reduce Clinical Event Rate Compared to Bare-Metal Stents. Long-Term Results From a Randomized Trial

Laura Mauri, MD; Elyse Foster, MD; Donald D. Glower, MD; Patricia Apruzzese, MS; Joseph M. Massaro, PhD; Howard C. Herrmann, MD; James Hermiller, MD; William Gray, MD; Andrew Wang, MD; Wesley R. Pedersen, MD; Tanvir Bajwa, MD; John Lasala, MD, PhD; Reginald Low, MD; Paul Grayburn, MD; Ted Feldman, MD

Objectives: This study sought to evaluate 4-year outcomes of percutaneous repair versus surgery for mitral regurgitation.

01 agosto 2013

JACC: CARDIOVASCULAR INTERVENTIONS. Impact of Attenuated Plaque as Detected by Intravascular Ultrasound on the Occurrence of Microvascular Obstruction After Percutaneous Coronary Intervention in Patients With ST-Segment Elevation Myocardial Infarction

Yasutsugu Shiono, MD; Takashi Kubo, MD, PhD; Atsushi Tanaka, MD, PhD; Takashi Tanimoto, MD, PhD; Shingo Ota, MD; Yasushi Ino, MD, PhD; Hiroshi Aoki, MD; Yuichi Ozaki, MD; Makoto Orii, MD; Kunihiro Shimamura, MD; Kohei Ishibashi, MD; Takashi Yamano, MD; Tomoyuki Yamaguchi, MD; Kumiko Hirata, MD, PhD; Toshio Imanishi, MD, PhD; Takashi Akasaka, MD, PhD

Objectives: The aim of the study was to investigate whether intravascular ultrasound (IVUS) can predict microvascular obstruction (MVO) as detected by magnetic resonance imaging (MRI) after primary percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI).

01 julio 2013

JACC. Biodegradable Polymer Biolimus-Eluting Stent Versus Durable Polymer Everolimus-Eluting Stent. A Randomized, Controlled, Noninferiority Trial

Masahiro Natsuaki, MD; Ken Kozuma, MD; Takeshi Morimoto, MD; Kazushige Kadota, MD; Toshiya Muramatsu, MD; Yoshihisa Nakagawa, MD; Takashi Akasaka, MD; Keiichi Igarashi, MD; Kengo Tanabe, MD; Yoshihiro Morino, MD; Tetsuya Ishikawa, MD; Hideo Nishikawa, MD; Masaki Awata, MD; Mitsuru Abe, MD; Hisayuki Okada, MD; Yoshiki Takatsu, MD; Nobuhiko Ogata, MD; Kazuo Kimura, MD; Kazushi Urasawa, MD; Yasuhiro Tarutani, MD; Nobuo Shiode, MD; Takeshi Kimura, MD

Objectives: NEXT (NOBORI Biolimus-Eluting Versus XIENCE/PROMUS Everolimus-Eluting Stent Trial) was designed for evaluating the noninferiority of a biolimus-eluting stent (BES) relative to an everolimus-eluting stent (EES) in terms of target lesion revascularization (TLR) at 1 year.

01 octubre 2013

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Aortic Regurgitation and Left Ventricular Remodeling After Transcatheter Aortic Valve Implantation. A Serial Cardiac Magnetic Resonance Imaging Study

Constanze Merten, MD, Hans-Wilko Beurich, MD, Dirk Zachow, MD, Ahmad E. Mostafa, MD, Volker Geist, MD, Ralph Toelg, MD, Gert Richardt, MD and Mohamed Abdel-Wahab, MD

Background—Aortic regurgitation (AR) after transcatheter aortic valve implantation (TAVI) has been associated with poor outcomes, but little is known about how it evolves over time. We evaluated left ventricular (LV) function, remodeling, and the occurrence and evolution of AR after TAVI by using cardiac MRI.

01 julio 2013

JACC. Transcatheter Aortic Valve Replacement in EuropeAdoption Trends and Factors Influencing Device Utilization

Darren Mylotte, MD; Ruben L.J. Osnabrugge, MSc; Stephan Windecker, MD; Thierry Lefèvre, MD; Peter de Jaegere, MD, PhD; Raban Jeger, MD; Peter Wenaweser, MD; Francesco Maisano, MD; Neil Moat, MD; Lars Søndergaard, MD; Johan Bosmans, PhD; Rui C. Teles, MD; Giuseppe Martucci, MD; Ganesh Manoharan, MD; Eulogio Garcia, MD; Nicolas M. Van Mieghem, MD; A. Pieter Kappetein, MD, PhD; Patrick W. Serruys, MD, PhD; Ruediger Lange, MD, PhD; Nicolo Piazza, MD, PhD

Objectives: The authors sought to examine the adoption of transcatheter aortic valve replacement (TAVR) in Western Europe and investigate factors that may influence the heterogeneous use of this therapy.

01 agosto 2013

JACC: CARDIOVASCULAR INTERVENTIONS. Complete Revascularization Is Not a Prerequisite for Success in Current Transcatheter Aortic Valve Implantation Practice

Nicolas M. Van Mieghem, MD; Robert M. van der Boon, MSc; Elhamula Faqiri, MSc; Roberto Diletti, MD; Carl Schultz, MD, PhD; Robert-Jan van Geuns, MD, PhD; Patrick W. Serruys, MD, PhD; Arie-Pieter Kappetein, MD, PhD; Ron T. van Domburg, PhD; Peter P. de Jaegere, MD, PhD

Objectives This study sought to assess in patients undergoing transcatheter aortic valve implantation (TAVI), the prevalence and impact of incomplete coronary revascularization defined as >50% coronary artery or graft diameter stenosis on visual assessment of the coronary angiogram.

01 agosto 2013

AMERICAN HEART JOURNAL. Study Design and Rationale of “A Multicenter, Open-Labeled, Randomized Controlled Trial Comparing Three 2nd-Generation Drug-Eluting Stents in Real-World Practice” (CHOICE trial)

Young Jin Youn, MD , Jun-Won Lee, MD , Sung Gyun Ahn, MD , Seung-Hwan Lee, MD , Hyun Hee Choi, MD , Hyunmin Choi, MD , Cheol Ung Choi, MD , Jin Bae Lee, MD , Jang Hyun Cho, MD , Tae Soo Kang, MD , Byung Ryul Cho, MD , Kwang Soo Cha, MD , Moo Hyun Kim, MD , Min Su Hyon, MD , Sang-Sig Cheong, MD , Do-Sun Lim, MD , Kyoo Rok Han, MD , Myung Ho Jeong, MD , Keum Soo Park, MD , Junghan Yoon, MD

Background: The second-generation drug-eluting stents (DES) have shown superiority in many studies relating to safety and efficacy when compared with the first-generation DES. However, it is unclear whether there are differences in efficacy and safety among the second-generation DES after long-term follow-up.

01 agosto 2013

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Relationship Between ST-Segment Recovery and Clinical Outcomes After Primary Percutaneous Coronary Intervention. The HORIZONS-AMI ECG Substudy Report

Michael E. Farkouh, MD, MSc, James Reiffel, MD, Ovidiu Dressler, MD, Eugenia Nikolsky, MD, PhD, Helen Parise, ScD, Ecatarina Cristea, MD, David A. Baran, MD, Jose Dizon, MD, Jacques P. Merab, MD, Alexandra J. Lansky, MD, Roxana Mehran, MD and Gregg W. Stone, MD

Background—In patients with ST-segment elevation myocardial infarction undergoing thrombolytic therapy, the degree of ST-segment resolution (STR) correlates with long-term cardiovascular mortality. The long-term predictive value of STR after primary percutaneous coronary intervention (PCI) is less well understood. We sought to determine the long-term prognostic value of STR after primary PCI in ST-segment–elevation myocardial infarction.