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ESTUDIOS


01 enero 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Impact of Coronary Anatomy and Stenting Technique on Long-Term Outcome After Drug-Eluting Stent Implantation for Unprotected Left Main Coronary Artery Disease

Klaus Tiroch, MD∗; Julinda Mehilli, MD†; Robert A. Byrne, MB§; Stefanie Schulz, MD§; Steffen Massberg, MD†; Karl-Ludwig Laugwitz, MD‡; Marc Vorpahl, MD∗; Melchior Seyfarth, MD∗; Adnan Kastrati, MD‡

Objectives: This study sought to evaluate the impact of anatomic and procedural variables on the outcome of the unprotected left main coronary artery (uLMCA) itself after drug-eluting stent (DES) implantation.

01 enero 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Initial Success Rate of Percutaneous Coronary Intervention for Chronic Total Occlusion in a Native Coronary Artery Is Decreased in Patients Who Underwent Previous Coronary Artery Bypass Graft Surgery

Tomohiko Teramoto, MD, PhD∗; Etsuo Tsuchikane, MD, PhD∗; Hitoshi Matsuo, MD, PhD†; Yoriyasu Suzuki, MD‡; Tsuyoshi Ito, MD∗; Tatsuya Ito, MD‡; Maoto Habara, MD∗; Kenya Nasu, MD∗; Masashi Kimura, MD, PhD∗; Yoshihisa Kinoshita, MD∗; Mitsuyasu Terashima, MD, PhD∗; Yasushi Asakura, MD∗; Tetsuo Matsubara, MD∗; Takahiko Suzuki, MD, PhD∗

Objectives: This study sought to compare the initial success rate of percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) in a native coronary artery (NCA) in patients with and without previous coronary artery bypass grafting (CABG) and to assess predictive factors.

01 enero 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Periprocedural Myocardial Injury in Chronic Total Occlusion Percutaneous Interventions

Nathan Lo, MD∗; Tesfaldet T. Michael, MD, MPH†; Danyaal Moin, MD∗; Vishal G. Patel, MD†; Mohammed Alomar, MD†; Aristotelis Papayannis, MD†; Daisha Cipher, PhD‡; Shuaib M. Abdullah, MD†; Subhash Banerjee, MD†; Emmanouil S. Brilakis, MD, PhD†

Objectives: This study sought to evaluate the incidence, correlates, and clinical implications of periprocedural myocardial injury (PMI) during percutaneous coronary intervention (PCI) of chronic total occlusions (CTO).

01 enero 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Comparison of Newer-Generation Drug-Eluting With Bare-Metal Stents in Patients With Acute ST-Segment Elevation Myocardial Infarction. A Pooled Analysis of the EXAMINATION (clinical Evaluation of the Xience-V stent in Acute Myocardial INfArcTION) and COMFORTABLE-AMI (Comparison of Biolimus Eluted From an Erodible Stent Coating With Bare Metal Stents in Acute ST-Elevation Myocardial Infarction) Trials

Manel Sabaté, MD, PhD∗; Lorenz Räber, MD†; Dik Heg, PhD‡; Salvatore Brugaletta, MD, PhD∗; Henning Kelbaek, MD, PhD§; Angel Cequier, MD, PhD‖; Miodrag Ostojic, MD, PhD¶; Andrés Iñiguez, MD, PhD#; David Tüller, MD, PhD∗∗; Antonio Serra, MD††; Andreas Baumbach, MD, PhD‡‡; Clemens von Birgelen, MD, PhD§§; Rosana Hernandez-Antolin, MD, PhD‖‖; Marco Roffi, MD, PhD¶¶; Vicente Mainar, MD##; Marco Valgimigli, MD, PhD∗∗∗; Patrick W. Serruys, MD, PhD†††; Peter Jüni, MD‡; Stephan Windecker, MD†

Objectives: This study sought to study the efficacy and safety of newer-generation drug-eluting stents (DES) compared with bare-metal stents (BMS) in an appropriately powered population of patients with ST-segment elevation myocardial infarction (STEMI).

01 julio 2014

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Advances in Interventional Cardiology. Management of Antiplatelet and Anticoagulant Therapy in Patients With Atrial Fibrillation in the Setting of Acute Coronary Syndromes or Percutaneous Coronary Interventions

Davide Capodanno, MD, PhD and Dominick J. Angiolillo, MD, PhD

Introduction: Atrial fibrillation (AF), the most common cardiac arrhythmia, occurs in 1% to 2% of the general population, with a prevalence varying from 0.5% in subjects 40 to 50 years old to 5% to 15% in the elderly who are >80 years old.1–3 Stroke is the most feared complication of AF, resulting in death or disabling symptoms in a vast proportion of cases.4 In the Framingham study, the age-adjusted incidence of stroke was 5-fold higher in subjects with AF, and the attributable risk raised from 1.5% at 50 to 59 years to 23.5% at 80 to 89 years.5

01 julio 2014

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Images and Case Reports in Interventional Cardiology. Successful Endovascular Stroke Rescue With Retrieval of an Embolized Calcium Fragment After Transcatheter Aortic Valve Replacement

Amir-Ali Fassa, MD, Mikael Mazighi, MD, PhD, Dominique Himbert, MD, Lydia Deschamps, MD, Gregory Ducrocq, MD, Adrian P. Cheong, MD, Jean-Pol Depoix, MD, Marie-Pierre Dilly, MD, Soleiman Alkhoder, MD, Bruno Mourvillier, MD and Alec Vahanian, MD

Introduction: A 90-year-old symptomatic woman with a critical aortic stenosis was referred for transcatheter aortic valve replacement (TAVR). The procedure was performed under locoregional anesthesia from a right femoral approach, with the successful implantation of a 23-mm CoreValve (Medtronic Inc, Minneapolis, MN). Echocardiographic assessment after TAVR showed a mean transprosthetic gradient of 16 mm Hg and trace paravalvular regurgitation. After percutaneous closure of the right femoral artery, the patient suddenly became unresponsive. After prompt intubation, emergency cerebral MRI was performed to assess the presence of reversible ischemia and exclude parenchymal hemorrhage, showing partial occlusion of the right middle cerebral artery with ischemia in the corresponding territory (Figure 1). Conventional cerebral angiography confirmed partial M1-M2 occlusion of the right middle cerebral artery (Figure 2A; Movie I in the Data Supplement). Complete revascularization was achieved using a 4.0×20 mm Solitaire FR retrievable stent (ev3, Irvine, CA) with capture of the embolic material (Figure 2B; Movies II and III in the Data Supplement). The onset-to- reperfusion delay was 150 minutes.

01 marzo 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Percutaneous Left Atrial Appendage Occlusion for Stroke Prophylaxis in Nonvalvular Atrial Fibrillation. A Systematic Review and Analysis of Observational Studies

Navkaranbir Singh Bajaj, MD∗; Akhil Parashar, MD†; Shikhar Agarwal, MD, MPH†; Nishtha Sodhi, MD‡; Kanhaiya Lal Poddar, MD†; Aatish Garg, MD‡; E. Murat Tuzcu, MD†; Samir R. Kapadia, MD†

Objectives: The goal of this study was to provide a systematic review and analysis of observational studies on percutaneous left atrial appendage (LAA) occlusion for stroke prophylaxis in nonvalvular atrial fibrillation (NVAF).

01 marzo 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Intravascular Ultrasound-Guided Implantation of Drug-Eluting Stents to Improve Outcome

Jae-Sik Jang, MD, PhD∗; Yeo-Jeong Song, MD∗; Wook Kang, MD∗; Han-Young Jin, MD∗; Jeong-Sook Seo, MD, PhD∗; Tae-Hyun Yang, MD, PhD∗; Dae-Kyeong Kim, MD, PhD∗; Kyoung-Im Cho, MD, PhD†; Bo-Hyun Kim, MD, PhD‡; Yong Hyun Park, MD, PhD§; Hyung-Gon Je, MD, PhD§; Dong-Soo Kim, MD, PhD∗

Objectives: The aim of this study was to systematically review and perform a meta-analysis of randomized trials and observational studies of intravascular ultrasound (IVUS)-guided versus angiography-guided implantation of drug-eluting stents (DES).

01 marzo 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Clinical Impact of Intravascular Ultrasound Guidance in Drug-Eluting Stent Implantation for Unprotected Left Main Coronary Disease

Jose M. de la Torre Hernandez, MD, PhD∗; José A. Baz Alonso, MD†; Joan A. Gómez Hospital, MD, PhD‡; Fernando Alfonso Manterola, MD, PhD§; Tamara Garcia Camarero, MD∗; Federico Gimeno de Carlos, MD, PhD‖; Gerard Roura Ferrer, MD‡; Angel Sanchez Recalde, MD¶; Íñigo Lozano Martínez-Luengas, MD, PhD#; Josep Gomez Lara, MD‡; Felipe Hernandez Hernandez, MD∗∗; María J. Pérez-Vizcayno, MD§; Angel Cequier Fillat, MD, PhD‡; Armando Perez de Prado, MD††; Agustín Albarrán Gonzalez-Trevilla, MD∗∗; Manuel F. Jimenez Navarro, MD, PhD‡‡; Josepa Mauri Ferre, MD§§; Jose A. Fernandez Diaz, MD‖‖; Eduardo Pinar Bermudez, MD, PhD¶¶; Javier Zueco Gil, MD∗

Objectives: This study sought to investigate the clinical impact of the use of intravascular ultrasound (IVUS) during revascularization of patients with left main coronary artery (LM) disease with drug-eluting stents (DES).

01 marzo 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Differential Prognostic Impact of Treatment Strategy Among Patients With Left Main Versus Non–Left Main Bifurcation Lesions Undergoing Percutaneous Coronary Intervention. Results From the COBIS (Coronary Bifurcation Stenting) Registry II

Young Bin Song, MD, PhD∗; Joo-Yong Hahn, MD, PhD∗; Jeong Hoon Yang, MD, PhD∗; Seung-Hyuk Choi, MD, PhD∗; Jin-Ho Choi, MD, PhD∗; Sang Hoon Lee, MD, PhD∗; Myung-Ho Jeong, MD, PhD†; Hyo-Soo Kim, MD, PhD‡; Jae-Hwan Lee, MD, PhD§; Cheol Woong Yu, MD, PhD‖; Seung Woon Rha, MD, PhD¶; Yangsoo Jang, MD, PhD#; Jung Han Yoon, MD, PhD∗∗; Seung-Jea Tahk, MD, PhD††; Ki Bae Seung, MD, PhD‡‡; Ju Hyeon Oh, MD, PhD§§; Jong-Seon Park, MD, PhD‖‖; Hyeon-Cheol Gwon, MD, PhD∗

Objectives: The authors sought to investigate whether the impact of treatment strategies on clinical outcomes differed between patients with left main (LM) bifurcation lesions and those with non-LM bifurcation lesions.

01 marzo 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Impact of Nonculprit Vessel Myocardial Perfusion on Outcomes of Patients Undergoing Percutaneous Coronary Intervention for Acute Coronary Syndromes. Analysis From the ACUITY Trial (Acute Catheterization and Urgent Intervention Triage Strategy)

Alexandra J. Lansky, MD∗; Vivian G. Ng, MD∗; Stephanie Meller, MD∗; Ke Xu, PhD†; Martin Fahy, MSc†; Frederick Feit, MD‡; E. Magnus Ohman, MD§; Harvey D. White, MD‖; Roxana Mehran, MD¶; Michel E. Bertrand, MD#; Walter Desmet, MD∗∗; Martial Hamon, MD††; Gregg W. Stone, MD†

Objectives: This study evaluated the impact of nonculprit vessel myocardial perfusion on outcomes of non–ST-segment elevation acute coronary syndromes (NSTE-ACS) patients.

01 marzo 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Utilization of Radial Artery Access for Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction in New York

Edward L. Hannan, PhD∗; Louise Szypulski Farrell, MS∗; Gary Walford, MD†; Peter B. Berger, MD‡; Nicholas J. Stamato, MD§; Ferdinand J. Venditti, MD‖; Alice K. Jacobs, MD¶; David R. Holmes, MD#; Samin Sharma, MD∗∗; Spencer B. King, MD††

Objectives: This study sought to determine the utilization and outcomes for radial access for percutaneous coronary intervention (PCI) for ST-segment elevation acute myocardial infarction (STEMI) in common practice.

01 marzo 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Aortic Regurgitation After Transcatheter Aortic Valve Implantation With Balloon- and Self-Expandable Prostheses

Mohamed Abdel-Wahab, MD∗; Thomas Comberg, MD†; Heinz Joachim Büttner, MD†; Mohamed El-Mawardy, MD∗; Kenichi Chatani, MD∗; Michael Gick, MD†; Volker Geist, MD∗; Gert Richardt, MD∗; Franz-Josef Neumann, MD†

Objectives: This study sought to assess aortic regurgitation (AR) after transcatheter aortic valve implantation (TAVI) with the self-expandable Medtronic CoreValve (MCV) (Medtronic Inc., Minneapolis, Minnesota) versus balloon-expandable Edwards Sapien XT valve (ESV) (Edwards Lifesciences, Irvine, California).

01 marzo 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Comparison of Medtronic CoreValve and Edwards Sapien XT for Transcatheter Aortic Valve Implantation. The Need for an Imaging-Based Personalized Approach in Device Selection

Javaid Iqbal, PhD†; Patrick W. Serruys, MD, PhD†

Transcatheter aortic valve implantation (TAVI) has revolutionized the treatment of symptomatic severe aortic stenosis in patients at a high risk of surgical valve replacement 1. The 2 main devices in clinical use at present are the self-expandable Medtronic CoreValve (MCV) (Medtronic, Minneapolis, Minnesota) and balloon-expandable Edwards SAPIEN XT valve (ESV) (Edwards Lifesciences, Irvine, California). Paravalvular aortic regurgitation (AR) is not an uncommon complication after TAVI, and suboptimal device sizing and positioning are the main culprits (2).

02 diciembre 2014

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Coronary Interventions. Clinical Presentation and Outcomes of Coronary In-Stent Restenosis Across 3-Stent Generations

Marco A. Magalhaes, MD, Sa’ar Minha, MD, Fang Chen, PhD, Rebecca Torguson, MPH, Al Fazir Omar, MD, Joshua P. Loh, MBBS, Ricardo O. Escarcega, MD, Michael J. Lipinski, MD, PhD, Nevin C. Baker, DO, Hironori Kitabata, MD, PhD, Hideaki Ota, MD, William O. Suddath, MD, Lowell F. Satler, MD, Augusto D. Pichard, MD and Ron Waksman, MD

Background: Clinical presentation of bare metal stent in-stent restenosis (ISR) in patients undergoing target lesion revascularization is well characterized and negatively affects on outcomes, whereas the presentation and outcomes of first- and second-generation drug-eluting stents (DESs) remains under-reported.

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