01 enero 2014

JACC: CARDIOVASCULAR INTERVENTIONS. A Next-Generation Bioresorbable Coronary Scaffold System: From Bench to First Clinical Evaluation. 6- and 12-Month Clinical and Multimodality Imaging Results

Stefan Verheye, MD, PhD∗; John A. Ormiston, MB ChB†; James Stewart, MD†; Mark Webster, MD‡; Elias Sanidas, MD∗; Ricardo Costa, MD, PhD§; J. Ribamar Costa, MD§; Daniel Chamie, MD, PhD§; Andrea S. Abizaid, MD, PhD§; Ibraim Pinto, MD, PhD§; Lynn Morrison, MPH‖; Sara Toyloy, BS‖; Vinayak Bhat, PhD‖; John Yan, MS‖; Alexandre Abizaid, MD, PhD§

Objectives: This study sought to perform clinical and imaging assessments of the DESolve Bioresorbable Coronary Scaffold (BCS).

01 enero 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Short- and Long-Term Implications of a Bioresorbable Vascular Scaffold Implantation on the Local Endothelial Shear Stress Patterns

Christos V. Bourantas, MD, PhD∗; Michail I. Papafaklis, MD, PhD†; Hector M. Garcia-Garcia, MD, PhD∗; Vasim Farooq, MBChB∗; Roberto Diletti, MD∗; Takashi Muramatsu, MD, PhD∗; Yaojun Zhang, MD, PhD∗; Fanis G. Kalatzis, PhD‡; Katerina K. Naka, MD, PhD§; Dimitrios I. Fotiadis, PhD‡; Yoshinobu Onuma, MD∗; Lampros K. Michalis, MD§; Patrick W. Serruys, MD, PhD∗

The angiographic and optical coherence tomographic data acquired at baseline and at 2-year follow-up from a 59-year-old patient, who had been implanted with an Absorb bioresorbable vascular scaffold (Absorb BVS, Abbott Vascular, Santa Clara, California), were fused to reconstruct the coronary anatomy of the treated left anterior descending artery 1. Blood flow simulation was performed and the endothelial shear stress (ESS) was computed at these 2 time points and portrayed on the luminal surface with the use of a color-coded map (Figure 1) 2. The rugged surface created at baseline following scaffold implantation resulted in predominantly low ESS (62.6% of the segment had ESS <1 Pa) that predisposed to neointimal formation. At 2-year follow-up, the ESS distribution was normalized and only 16.5% of the scaffolded segment had ESS <1 Pa, whereas the developed neointima had a mean thickness of 160 μm and covered the vessel wall.

01 enero 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Three-Dimensional Optical Coherence Tomography for Guidance of Complex Percutaneous Coronary Interventions

Jurgen M.R. Ligthart, RT; Roberto Diletti, MD; Karen Witberg, RN; Carl Schultz, MD, PhD

A 74-year-old man presented with stable angina and a positive stress test 5 months after a percutaneous coronary intervention (PCI). The index PCI involved stenting of the proximal left anterior descending coronary artery (LAD) across a diagonal branch (D1) followed by stenting of the diagonal, resulting in strut protrusion into the LAD, with the T-stenting and small protrusion technique (strut protrusion into the main branch) without further main-branch balloon or kissing balloon, but with a good angiographic result.

01 enero 2015

JACC: CARDIOVASCULAR INTERVENTIONS. Annular Rupture During Transcatheter Aortic Valve Replacement. Classification, Pathophysiology, Diagnostics, Treatment Approaches, and Prevention

Miralem Pasic, MD, PhD; Axel Unbehaun, MD; Semih Buz, MD; Thorsten Drews, MD, PhD; Roland Hetzer, MD, PhD

Annular rupture is an umbrella term covering different procedural-related injuries that may occur in the region of the aortic root and the left ventricular outflow tract during transcatheter aortic valve replacement. According to the anatomical location of the injury, there are 4 main types: supra-annular, intra-annular, subannular, and combined rupture. Annular rupture is a rare, unpredictable, and potentially fatal complication. It can be treated successfully if it is immediately recognized and adequately managed. The type of therapy depends on the location of the annular rupture and the nature of the clinical manifestations. Treatment approaches include conventional cardiac procedure, isolated pericardial drainage, and conservative therapy. This summary describes theoretical and practical considerations of the etiology, pathophysiology, classification, natural history, diagnostic and treatment strategies, and prevention approaches of annular rupture.

01 enero 2015

JACC: CARDIOVASCULAR INTERVENTIONS. Access Site Practice and Procedural Outcomes in Relation to Clinical Presentation in 439,947 Patients Undergoing Percutaneous Coronary Intervention in the United Kingdom

Karim Ratib, MB ChB∗; Mamas A. Mamas, BM BCh, DPhil†; Simon G. Anderson, MBBCh, PhD‡; Gurbir Bhatia, MD§; Helen Routledge, MD‖; Mark De Belder, MA, MD¶; Peter F. Ludman, MA, MD#; Douglas Fraser, MB BChir†; James Nolan, MD∗

Objectives: This study sought to determine the relationships among access site practice, clinical presentation, and procedural outcomes in a large patient population.

01 enero 2015

JACC: CARDIOVASCULAR INTERVENTIONS. Comparison of Sirolimus-Eluting Stenting With Minimally Invasive Bypass Surgery for Stenosis of the Left Anterior Descending Coronary Artery. 7-Year Follow-Up of a Randomized Trial

Stephan Blazek, MD∗; Cornelius Rossbach, BSc∗; Michael A. Borger, MD†; Georg Fuernau, MD∗; Steffen Desch, MD∗; Ingo Eitel, MD∗; Thomas Stiermaier, MD∗; Philipp Lurz, MD∗; David Holzhey, MD†; Gerhard Schuler, MD∗; Friedrich-Wilhelm Mohr, MD†; Holger Thiele, MD∗

Objectives: The aim of this analysis was to assess the 7-year long-term safety and effectiveness of a randomized comparison of percutaneous coronary intervention (PCI) with sirolimus-eluting stents (SES) versus minimally invasive direct coronary artery bypass (MIDCAB) surgery for the treatment of isolated proximal left anterior descending lesions.

01 enero 2015

JACC: CARDIOVASCULAR INTERVENTIONS. An Angiographic Tool for Risk Prediction of Side Branch Occlusion in Coronary Bifurcation Intervention. The RESOLVE Score System (Risk prEdiction of Side branch OccLusion in coronary bifurcation interVEntion)

Kefei Dou, MD∗; Dong Zhang, MD∗; Bo Xu, MBBS∗; Yuejin Yang, MD∗; Dong Yin, MD∗; Shubin Qiao, MD∗; Yongjian Wu, MD∗; Hongbing Yan, MD∗; Shijie You, MD∗; Yang Wang, MSc∗; Zhenqiang Wu, MSc∗; Runlin Gao, MD∗; Ajay J. Kirtane, MD, SM†

Objectives: The purpose of this study was to establish a scoring system to evaluate the risk of side branch (SB) occlusion in patients undergoing coronary bifurcation intervention.

01 enero 2015

JACC: CARDIOVASCULAR INTERVENTIONS. Middle-of-the-Night Percutaneous Coronary Intervention and its Association With Percutaneous Coronary Intervention Outcomes Performed the Following Day

Herbert D. Aronow, MD, MPH∗; Hitinder S. Gurm, MD†; James C. Blankenship, MD‡; Charles A. Czeisler, MD§; Tracy Y. Wang, MD, MHS, MSc‖; Lisa A. McCoy, MS‖; Megan L. Neely, PhD‖; John A. Spertus, MD¶

Objectives: This study sought to compare in-hospital mortality and bleeding complications for procedures performed by sleep-deprived versus non–sleep-deprived operators.

01 enero 2015

JACC: CARDIOVASCULAR INTERVENTIONS. Predictors and Clinical Outcomes of Permanent Pacemaker Implantation After Transcatheter Aortic Valve Replacement. The PARTNER (Placement of AoRtic TraNscathetER Valves) Trial and Registry

Tamim M. Nazif, MD∗; José M. Dizon, MD∗; Rebecca T. Hahn, MD∗; Ke Xu, PhD†; Vasilis Babaliaros, MD‡; Pamela S. Douglas, MD§; Mikhael F. El-Chami, MD‡; Howard C. Herrmann, MD‖; Michael Mack, MD¶; Raj R. Makkar, MD#; D. Craig Miller, MD∗∗; Augusto Pichard, MD††; E. Murat Tuzcu, MD‡‡; Wilson Y. Szeto, MD‖; John G. Webb, MD§§; Jeffrey W. Moses, MD∗; Craig R. Smith, MD∗; Mathew R. Williams, MD∗; Martin B. Leon, MD∗; Susheel K. Kodali, MD∗

Objectives: The purpose of this study was to identify predictors and clinical implications of permanent pacemaker (PPM) implantation after transcatheter aortic valve replacement (TAVR).

01 marzo 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Effect of the Endothelial Shear Stress Patterns on Neointimal Proliferation Following Drug-Eluting Bioresorbable Vascular Scaffold Implantation

Christos V. Bourantas, MD, PhD∗; Michail I. Papafaklis, MD, PhD†; Anna Kotsia, MD‡; Vasim Farooq, MB, ChB∗; Takashi Muramatsu, MD, PhD∗; Josep Gomez-Lara, MD, PhD∗; Yao-Jun Zhang, MD, PhD∗; Javaid Iqbal, PhD∗; Fanis G. Kalatzis, MD, PhD§; Katerina K. Naka, MD, PhD‡; Dimitrios I. Fotiadis, PhD§; Cecile Dorange, MSc‖; Jin Wang, PhD¶; Richard Rapoza, PhD¶; Hector M. Garcia-Garcia, MD, PhD∗; Yoshinobu Onuma, MD∗; Lampros K. Michalis, MD‡; Patrick W. Serruys, MD, PhD∗

Objectives: This study sought to investigate the effect of endothelial shear stress (ESS) on neointimal formation following an Absorb bioresorbable vascular scaffold (BVS) (Abbott Vascular, Santa Clara, California) implantation.

01 marzo 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Provisional Stenting of Coronary Bifurcations. Insights Into Final Kissing Balloon Post-Dilation and Stent Design by Computational Modeling

Peter Mortier, PhD∗; Yutaka Hikichi, MD‡; Nicolas Foin, PhD§; Gianluca De Santis, PhD∗; Patrick Segers, PhD†; Benedict Verhegghe, PhD∗; Matthieu De Beule, PhD∗

Objectives: This study sought to better understand and optimize provisional main vessel stenting with final kissing balloon dilation (FKBD).

01 marzo 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Extreme Brachial Loop

Isaac R. Whitman, MD; Andrew J. Boyle, MBBS, PhD

A 47-year-old man with prior right ulnar collateral ligament reconstruction presented with angina and was referred for cardiac catheterization. Right radial artery angiogram was normal (Figure 1A, Online Video 1). A J-tip guidewire met resistance just above the elbow. A subsequent brachial angiogram revealed an extremely tortuous recurrent brachial artery loop (Figure 1B and Figure 1C, Online Videos 2 and 3). The transradial approach is increasingly common in coronary angiography, reducing the risk of access site complications (1,). Full radial artery loops occur in 1% to 2% of patients, and can often be straightened with a guidewire (3,). However, the prevalence and challenges presented by brachial artery loops are not discussed in the literature. Furthermore, it is not known whether these tend to occur unilaterally or bilaterally, so there are no data guiding the choice between contralateral radial artery versus femoral artery as the alternative access site. Our decision was to attempt contralateral radial access. That decision proved prudent, as the patient´s left upper extremity demonstrated normal anatomy

01 marzo 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Optical Coherence Tomography Appearances in Healed Coronary Artery Aneurysms After Stent Implantation

Girish N. Viswanathan, MBBS, MD∗; Saqib Chowdhary, MBBS, PhD†; Richard A. Anderson, BSc, MBBS, MD‡

We earlier reported late stent malapposition and marked coronary artery aneurysm (CAN) formation at the site of implantation of 2 bare-metal stents (BMS), Multilink Vision (Abbott Laboratories, Abbott Park, Illinois) and Liberte (Boston Scientific Corporation, Natick, Massachusetts), to the proximal left anterior descending artery (LAD) and right coronary artery (RCA), respectively, in a woman treated for stable angina in 2006. The patient also had a Xience drug-eluting stent (DES) (Abbott Laboratories) to her mid RCA with less marked CAN on angiography in 2007 1. Diagnostic coronary angiography and optical coherence tomography (OCT) assessment was performed in 2012, although she remained free of symptoms or hospitalizations. Five years later, coronary angiography showed partial angiographic resolution of the CAN in the 2 BMS segments, with continued aneurysm formation at the Xience DES implantation site (Online Video 1 from 2007 and Online Videos 2, 3 and 4 from 2012).

01 enero 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Contemporary Incidence, Predictors, and Outcomes of Acute Kidney Injury in Patients Undergoing Percutaneous Coronary Interventions

Thomas T. Tsai, MD, MSc∗; Uptal D. Patel, MD‡; Tara I. Chang, MD, MS§; Kevin F. Kennedy, MS‖; Frederick A. Masoudi, MD, MSPH∗; Michael E. Matheny, MD, MSc, MPH∗∗; Mikhail Kosiborod, MD‖; Amit P. Amin, MD, MSc‖; John C. Messenger, MD∗; John S. Rumsfeld, MD, PhD∗; John A. Spertus, MD, MPH‖

Objectives: This study sought to examine the contemporary incidence, predictors and outcomes of acute kidney injury in patients undergoing percutaneous coronary interventions.

01 enero 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Two-Year Outcomes After First- or Second-Generation Drug-Eluting or Bare-Metal Stent Implantation in All-Comer Patients Undergoing Percutaneous Coronary Intervention. A Pre-Specified Analysis From the PRODIGY Study (PROlonging Dual Antiplatelet Treatment After Grading stent-induced Intimal hyperplasia studY)

Marco Valgimigli, MD, PhD∗; Matteo Tebaldi, MD†; Marco Borghesi, MD†; Pascal Vranckx, MD‡; Gianluca Campo, MD†; Carlo Tumscitz, MD†; Elisa Cangiano, MD†; Monica Minarelli, MD†; Antonella Scalone, MD†; Caterina Cavazza, MD†; Jlenia Marchesini, MD†; Giovanni Parrinello, PhD§

Objectives: This study sought to assess device-specific outcomes after implantation of bare-metal stents (BMS), zotarolimus-eluting Endeavor Sprint stents (ZES-S), paclitaxel-eluting stents (PES), or everolimus-eluting stents (EES) (Medtronic Cardiovascular, Santa Rosa, California) in all-comer patients undergoing percutaneous coronary intervention.