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ESTUDIOS


18 marzo 2014

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Routine Pressure Wire Assessment at Time of Diagnostic Angiography. Is It Ready for Prime Time?

Eric Van Belle, MD, PhD, Gilles Rioufol, MD, PhD and Patrick Dupouy, MD

To define the most appropriate therapeutical management plan in patients suspected of having coronary artery disease is becoming the ultimate goal in this population. Accumulated evidence suggests that our current practice has major flaws. The use of a noninvasive test as the key information to plan a coronary angiography can be questioned.

25 febrero 2014

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Congenital Heart Disease. Feasibility and Short-Term Outcomes of Percutaneous Transcatheter Pulmonary Valve Replacement in Small (<30 kg) Children With Dysfunctional Right Ventricular Outflow Tract Conduits

Darren P. Berman, MD, Doff B. McElhinney, MD, Julie A. Vincent, MD, William E. Hellenbrand, MD and Evan M. Zahn, MD

Background: In 2010, the Melody transcatheter pulmonary valve (TPV) received Food and Drug Administration approval for treatment of dysfunctional right ventricular outflow tract conduits in patients ≥30 kg. Limited data are available regarding use of this device in smaller patients.

18 febrero 2014

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Coronary Hemodynamics. Thermodilution-Derived Coronary Blood Flow Pattern Immediately After Coronary Intervention as a Predictor of Microcirculatory Damage and Midterm Clinical Outcomes in Patients With ST-Segment–Elevation Myocardial Infarction

Masashi Fukunaga, MD, Kenichi Fujii, MD, Daizo Kawasaki, MD, Hisashi Sawada, MD, Koujiro Miki, MD, Hiroto Tamaru, MD, Takahiro Imanaka, MD, Toshihiro Iwasaku, MD, Tsuyoshi Nakata, MD, Masahiko Shibuya, MD, Hirokuni Akahori, MD, Motomaru Masutani, MD, Kaoru Kobayashi, MD, Mitsumasa Ohyanagi, MD and Tohru Masuyama, MD

Background: Despite a sufficient coronary blood flow after primary percutaneous coronary intervention for patients with ST-segment–elevation myocardial infarction; some patients have a poor outcome because of microcirculatory damage. This study evaluates whether the thermodilution-derived coronary blood flow parameters immediately after primary percutaneous coronary intervention predict early microvascular damage and midterm outcomes in patients with ST-segment–elevation myocardial infarction.

25 marzo 2014

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Coronary Hemodynamics. Intracoronary Stem Cell Infusion After Acute Myocardial Infarction

Renate de Jong, MD, Jaco H. Houtgraaf, MD, Sanaz Samiei, BSc, Eric Boersma, PhD and Henricus J. Duckers, MD, PhD

Background: Several cell-based therapies for adjunctive treatment of acute myocardial infarction have been investigated in multiple clinical trials, but the benefits still remain controversial. This meta-analysis aims to evaluate the efficacy of bone marrow–derived mononuclear cell (BMMNC) therapy in patients with acute myocardial infarction, but also explores the effect of newer generations of stem cells.

18 febrero 2014

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Coronary Interventions. Late Adverse Events After Implantation of Sirolimus-Eluting Stent and Bare-Metal Stent. Long-Term (5–7 Years) Follow-Up of the Coronary Revascularization Demonstrating Outcome Study-Kyoto Registry Cohort-2

Masahiro Natsuaki, MD, Takeshi Morimoto, MD, Yutaka Furukawa, MD, Yoshihisa Nakagawa, MD, Kazushige Kadota, MD, Kyohei Yamaji, MD, Kenji Ando, MD, Satoshi Shizuta, MD, Hiroki Shiomi, MD, Tomohisa Tada, MD, Junichi Tazaki, MD, Yoshihiro Kato, MD, Mamoru Hayano, MD, Mitsuru Abe, MD, Takashi Tamura, MD, Manabu Shirotani, MD, Shinji Miki, MD, Mitsuo Matsuda, MD, Mamoru Takahashi, MD, Katsuhisa Ishii, MD, Masaru Tanaka, MD, Takeshi Aoyama, MD, Osamu Doi, MD, Ryuichi Hattori, MD, Masayuki Kato, MD, Satoru Suwa, MD, Akinori Takizawa, MD, Yoshiki Takatsu, MD, Eiji Shinoda, MD, Hiroshi Eizawa, MD, Teruki Takeda, MD, Jong-Dae Lee, MD, Moriaki Inoko, MD, Hisao Ogawa, MD, Shuichi Hamasaki, MD, Minoru Horie, MD, Ryuji Nohara, MD, Hirofumi Kambara, MD, Hisayoshi Fujiwara, MD, Kazuaki Mitsudo, MD, Masakiyo Nobuyoshi, MD, Toru Kita, MD and Takeshi Kimura, MD on behalf of the CREDO-Kyoto PCI/CABG registry cohort-2 investigators

Background: Late adverse events such as very late stent thrombosis (VLST) or late target-lesion revascularization (TLR) after first-generation sirolimus-eluting stents (SES) implantation have not been yet fully characterized at long term in comparison with those after bare-metal stent (BMS) implantation.

18 marzo 2014

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Coronary Interventions. Incomplete Stent Apposition Causes High Shear Flow Disturbances and Delay in Neointimal Coverage as a Function of Strut to Wall Detachment Distance

Nicolas Foin, MSc, PhD*, Juan Luis Gutiérrez-Chico, MD, PhD*, Shimpei Nakatani, MD*, Ryo Torii, MSc, PhD*, Christos V. Bourantas, MD, PhD, Sayan Sen, MD, PhD, Sukhjinder Nijjer, MD, Ricardo Petraco, MD, Chrysa Kousera, MSc, Matteo Ghione, MD, Yoshinobu Onuma, MD, Hector M. Garcia-Garcia, MD, PhD, Darrel P. Francis, MD, PhD, Philip Wong, MD, Carlo Di Mario, MD, PhD, Justin E. Davies, MD, PhD and Patrick W. Serruys, MD, PhD

Background: Lack of re-endothelialization and neointimal coverage on stent struts has been put forward as the main underlying mechanism leading to late stent thrombosis. Incomplete stent apposition (ISA) has been observed frequently in patients with very late stent thrombosis after drug eluting stent implantation, suggesting a role of ISA in the pathogenesis of this adverse event. The aim of this study was to evaluate the impact of different degrees of ISA severity on abnormal shear rate and healing response with coverage, because of its potential implications for stent optimization in clinical practice.

25 febrero 2014

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Coronary Interventions. Risk of Acute Kidney Injury After Percutaneous Coronary Interventions Using Radial Versus Femoral Vascular Access. Insights From the Blue Cross Blue Shield of Michigan Cardiovascular Consortium

Judith Kooiman, MSc, Milan Seth, MS, Simon Dixon, MD, David Wohns, MD, Thomas LaLonde, MD, Sunil V. Rao, MD and Hitinder S. Gurm, MD

Background: Transradial percutaneous coronary intervention (PCI [TRI]) does not involve catheter manipulation in the descending aorta, whereas transfemoral PCI (TFI) does. Therefore, the risk of acute kidney injury (AKI) after PCI might be influenced by vascular access site. We compared risks of AKI and nephropathy requiring dialysis (NRD) among patients treated with TRI and TFI.

08 abril 2014

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Coronary Interventions. Optical Coherence Tomographic Evaluation of Transplant Coronary Artery Vasculopathy With Correlation to Cellular Rejection

Liang Dong, MD, Akiko Maehara, MD, Tamim M. Nazif, MD, Ari T. Pollack, MD, Shigeo Saito, MD, LeRoy E. Rabbani, MD, Mark A. Apfelbaum, MD, Kate Dalton, MS, RD, Jeffrey W. Moses, MD, Ulrich P. Jorde, MD, Ke Xu, PhD, Gary S. Mintz, MD, Donna M. Mancini, MD and Giora Weisz, MD

Background: Cardiac allograft vasculopathy is an accelerated fibroproliferative process that affects the coronary arteries of transplanted hearts. Intracoronary imaging with optical coherence tomography enables detection of subangiographic cardiac allograft vasculopathy.

01 abril 2014

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Coronary Interventions. Safety and Efficacy of a Potential Treatment Algorithm by Using Manual Compression Repair and Ultrasound-Guided Thrombin Injection for the Management of Iatrogenic Femoral Artery Pseudoaneurysm in a Large Patient Cohort

Marijana Dzijan-Horn, MD, Nicolas Langwieser, MD, Philipp Groha, MD, Christian Bradaric, MD, Maryam Linhardt, MD, Corinna Böttiger, MD, Robert A. Byrne, MB BCh, PhD, Birgit Steppich, MD, Tobias Koppara, MD, Julia Gödel, MD, Martin Hadamitzky, MD, Ilka Ott, MD, Nicolas von Beckerath, MD, Adnan Kastrati, MD, Karl-Ludwig Laugwitz, MD and Tareq Ibrahim, MD

Background: Because of the risk of associated complications, femoral pseudoaneurysm (PSA) formation implies further treatment. Ultrasound-guided thrombin injection (UGTI) is becoming the accepted gold standard, but manual compression (MC) represents an established treatment option including PSAs not feasible for UGTI. This study aims to assess our experience in PSA treatment using MC or UGTI according to a potential algorithm based on morphological properties in a large patient cohort.

08 abril 2014

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Myocardial Infarction. Prevention of Contrast-Induced Nephropathy With N-Acetylcysteine or Sodium Bicarbonate in Patients With ST-Segment–Myocardial Infarction

Per Thayssen, MD, DMSci, Jens Flensted Lassen, MD, PhD, Svend Eggert Jensen, MD, PhD, Knud Nørregaard Hansen, MD, Henrik Steen Hansen, MD, DMSci, Evald Høj Christiansen, MD, PhD, Anders Junker, MD, PhD, Jan Ravkilde, MD, DMSci, Leif Thuesen, MD, DMSci, Karsten Tange Veien, MD and Lisette Okkels Jensen, MD, DMSci, PhD

Background: Contrast-induced nephropathy (CIN) is a serious condition in patients with ST-segment–elevation myocardial infarction treated with primary percutaneous coronary intervention. We compared the risk of acute CIN and the influence of preventive strategies in patients with ST-segment–elevation myocardial infarction undergoing primary percutaneous coronary intervention.

01 abril 2014

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Myocardial Infarction. Remote Ischemic Postconditioning During Percutaneous Coronary Interventions

Shahar Lavi, MD, Sabrina D’Alfonso, MSc, Pantelis Diamantouros, MD, Anthony Camuglia, MD, Pallav Garg, MD, Patrick Teefy, MD, George Jablonsky, MD, Kumar Sridhar, MD and Ronit Lavi, MD

Background: Remote ischemic preconditioning may result in reduction in infarct size during percutaneous coronary intervention (PCI). It is unclear whether remote ischemic postconditioning (RIPost) will reduce the incidence of myocardial injury after PCI, and whether ischemic conditioning of a larger remote organ (thigh versus arm) would provide further myocardial protection.

01 febrero 2014

JOURNAL OF ENDOVASCULAR THERAPY. Carotid Artery Stenting in Patients With Left ICA Stenosis and Bovine Aortic Arch: A Single-Center Experience in 60 Consecutive Patients Treated Via the Right Radial or Brachial Approach

Piero Montorsi, MD1⇑ Stefano Galli, MD1 Paolo M. Ravagnani, MD1 Daniela Trabattoni, MD1 Franco Fabbiocchi, MD1 Alessandro Lualdi, MD1 Giovanni Ballerini, MD1 Daniele Andreini, MD1 Gianluca Pontone, MD1 Luigi Caputi, MD2 Antonio L. Bartorelli, MD1

Purpose: To assess the safety and efficacy of carotid artery stenting (CAS) of the left internal carotid artery (LICA) from a right radial/brachial approach in patients with bovine aortic arch.

01 febrero 2014

JOURNAL OF ENDOVASCULAR THERAPY. Impact of Long-Term Warfarin Treatment on EVAR Durability: A Meta-Analysis

Miltos K. Lazarides, MD, FEBVS⇑ George S. Georgiadis, MD Dimitrios G. Charalampidis, MD George A. Antoniou, MD, PhD Efstratios I. Georgakarakos, MD George Trellopoulos, MD

Purpose: To evaluate whether postoperative long-term oral anticoagulation affects the durability of endovascular aneurysm repair (EVAR) and whether it is associated with an increased incidence of endoleak and subsequent need for reintervention.

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