21 marzo 2014

CIRCULATION. Coronary Heart Disease. Five-Year Survival in Patients With ST-Segment–Elevation Myocardial Infarction According to Modalities of Reperfusion Therapy

Nicolas Danchin, MD, PhD; Etienne Puymirat, MD, PhD; Philippe Gabriel Steg, MD, PhD; Patrick Goldstein, MD; François Schiele, MD, PhD; Loïc Belle, MD; Yves Cottin, MD, PhD; Jean Fajadet, MD; Khalife Khalife, MD; Pierre Coste, MD, PhD; Jean Ferrières, MD, PhD; Tabassome Simon, MD, PhD; on behalf of the FAST-MI 2005 Investigators

Background: Although primary percutaneous coronary intervention (pPCI) is the preferred reperfusion method for ST-segment–elevation myocardial infarction, it remains difficult to implement in many areas, and fibrinolytic therapy is still widely used.

01 enero 2014

CIRCULATION. Images in Cardiovascular Medicine. A Surgical Case of Expanding Bilateral Coronary Aneurysms Regarded as Immunoglobulin G4-Related Disease

Yasuyuki Bito, MD, PhD; Yasuyuki Sasaki, MD, PhD; Hidekazu Hirai, MD, PhD; Mitsuharu Hosono, MD, PhD; Atsushi Nakahira, MD, PhD; Yasuo Suehiro, MD; Daisuke Kaku, MD; Yuko Kubota, MD, PhD; Makoto Miyabe, MD; Shigefumi Suehiro, MD, PhD

Introduction: A 69-year–old man was referred to our department for surgical treatment of bilateral giant coronary artery aneurysms. He had no apparent clinical factors associated with atherosclerosis, such as diabetes mellitus, hyperlipidemia, or hypertension.

01 enero 2014

CIRCULATION. Images in Cardiovascular Medicine. Multidetector Computed Tomographic Angiography Imaging of Pentalogy of Cantrell

Hui Liu, MD, PhD*; Yu-Hsiang Juan, MD*; Changhong Liang, MD, PhD; Jimei Chen, MD, PhD; Suixin Liang, MD; Zhaofeng Xie, MD; Raymond Y. Kwong, MD; Sachin S. Saboo, MD, FRCR

Introduction: A 4-day-old female mildly cyanotic neonate presented clinically with ventral herniation of the heart to the anterior abdominal wall and umbilical defect containing bowel loop

26 febrero 2014

CIRCULATION. Epidemiology and Prevention. Temporal Trends in Ischemic Heart Disease Mortality in 21 World Regions, 1980 to 2010

Andrew E. Moran, MD, MPH; Mohammad H. Forouzanfar, PhD; Gregory A. Roth, MD, MPH; George A. Mensah, MD; Majid Ezzati, PhD; Christopher J.L. Murray, MD, DPhil; Mohsen Naghavi, MD, MPH, PhD

Background: Ischemic heart disease (IHD) is the leading cause of death worldwide. The Global Burden of Diseases, Risk Factors and Injuries 2010 Study estimated global and regional IHD mortality from 1980 to 2010.

07 febrero 2014

CIRCULATION. Vascular Medicine. Racial and Regional Differences in Venous Thromboembolism in the United States in 3 Cohorts

Neil A. Zakai, MD, MSc; Leslie A. McClure, PhD; Suzanne E. Judd, PhD; Monika M. Safford, MD; Aaron R. Folsom, MD; Pamela L. Lutsey, PhD; Mary Cushman, MD, MSc

Background: Blacks are thought to have a higher risk of venous thromboembolism (VTE) than whites. However, prior studies are limited to administrative databases that lack specific information on VTE risk factors or have limited geographic scope.

01 enero 2014

CIRCULATION. Images in Cardiovascular Medicine. Cardiac Magnetic Resonance for Paravalvular Leaks in Post-Transcatheter Aortic Valve Replacement

Stamatios Lerakis, MD; Salim Hayek, MD; Chesnal D. Arepalli, MD; Vinod Thourani, MD; Vasilis Babaliaros, MD

Introduction: An 80-year–old man with known coronary artery disease presented with progressively worsening shortness of breath over the past few weeks. On transthoracic echocardiography (TTE) examination he was found to have severe aortic stenosis with an aortic valve area of 0.8 cm2.

24 febrero 2014

CIRCULATION. Valvular Heart Disease. Postprocedural Aortic Regurgitation in Balloon-Expandable and Self-Expandable Transcatheter Aortic Valve Replacement Procedures

Eric Van Belle, MD, PhD; Françis Juthier, MD; Sophie Susen, MD, PhD; André Vincentelli, MD, PhD; Bernard Iung, MD; Jean Dallongeville, MD, PhD; Hélène Eltchaninoff, MD; Marc Laskar, MD; Pascal Leprince, MD; Michel Lievre, MD, PhD; Carlo Banfi, MD, PhD; Jean-Luc Auffray, MD; Cedric Delhaye, MD; Patrick Donzeau-Gouge, MD; Karine Chevreul, MD, PhD; Jean Fajadet, MD; Alain Leguerrier, MD; Alain Prat, MD; Martine Gilard, MD; Emmanuel Teiger, MD, PhD; for the FRANCE 2 Investigators

Background: Significant postprocedural aortic regurgitation (AR) is observed in 10% to 20% of cases after transcatheter aortic valve replacement (TAVR). The prognostic value and the predictors of such a complication in balloon-expandable (BE) and self-expandable (SE) TAVR remain unclear.

24 febrero 2014

CIRCULATION. Valve Design and Paravalvular Aortic Regurgitation. New Insights from the French Registry

E. Murat Tuzcu, MD; Samir R. Kapadia, MD; Lars G. Svensson, MD, PhD

Transcatheter aortic valve replacement (TAVR) has emerged as an important treatment option for patients with severe aortic stenosis who are either inoperable or at high risk for surgical aortic valve replacement. Currently, 2 valves are approved by the Food and Drug Administration for inoperable patients, whereas 9 valves have received the CE (Conformité Européenne) mark in Europe for TAVR.

01 enero 2014

CIRCULATION. Clinician Update. Coronary Artery Computed Tomography Scanning

Carlo Nicola De Cecco, MD; Felix G. Meinel, MD; Salvatore A. Chiaramida, MD; Philip Costello, MD; Fabian Bamberg, MD, MPH; U. Joseph Schoepf, MD, FAHA

A 46-year-old woman with diabetes mellitus and a body mass index of 32 kg/m2 reports repeated episodes of chest pain after moderate activity. single photon emission computed tomography myocardial perfusion imaging demonstrates no electrocardiographic (EKG) abnormalities and a small fixed perfusion defect in the posterior left ventricle. Prospectively EKG-triggered coronary CT angiography (CCTA), performed with a radiation dose of 3.5 mSv, demonstrates unremarkable coronary arteries with no evidence of stenosis or atherosclerosis (Figure 1).

25 marzo 2014

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Onset of Antiplatelet Action With High (100 mg) Versus Standard (60 mg) Loading Dose of Prasugrel in Patients With ST-Segment–Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

Dimitrios Alexopoulos, MD, George Makris, MD, Ioanna Xanthopoulou, MD, Sotirios Patsilinakos, MD, Spyridon Deftereos, MD, Vassilios Gkizas, MD, Angelos Perperis, MD, Stavros Karanikas, MD, Christos Angelidis, MD, Grigorios Tsigkas, MD, Nikolaos Koutsogiannis, MD, George Hahalis, MD and Periklis Davlouros, MD

Background: In patients with ST-segment–elevation myocardial infarction undergoing primary percutaneous coronary intervention, a suboptimal degree of platelet inhibition for the first 2 hours after the standard 60 mg loading dose of prasugrel has been described.

25 febrero 2014

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Structural Heart Disease. Prognostic Implications of Pulmonary Hypertension in Patients With Severe Aortic Stenosis Undergoing Transcatheter Aortic Valve Implantation

Adrien Luçon, MD, Emmanuel Oger, MD, PhD, Marc Bedossa, MD, Dominique Boulmier, MD, Jean Philippe Verhoye, MD, PhD, Hélène Eltchaninoff, MD, PhD, Bernard Iung, MD, Alain Leguerrier, MD, PhD, Marc Laskar, MD, Pascal Leprince, MD, PhD, Martine Gilard, MD, PhD and Hervé Le Breton, MD, PhD

Background: Pulmonary hypertension (PH) is associated with poor prognosis in patients with severe aortic stenosis. The aim of this multicenter study was to describe clinical outcome after transcatheter aortic valve implantation.

18 marzo 2014

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Structural Heart Disease. Does Routine Pressure Wire Assessment Influence Management Strategy at Coronary Angiography for Diagnosis of Chest Pain?

Nick Curzen, BM, PhD, Omar Rana, MD, Zoe Nicholas, BSc, Peter Golledge, MD, Azfar Zaman, MD, Keith Oldroyd, MD, Colm Hanratty, MD, Adrian Banning, MD, Stephen Wheatcroft, MD, Alex Hobson, MD, Kam Chitkara, MBBS, David Hildick-Smith, MD, Dan McKenzie, MBBS, Alison Calver, MD, Borislav D. Dimitrov, MD, PhD and Simon Corbett, MB BChir, PhD

Background: The use of coronary angiography (CA) for diagnosis and management of chest pain (CP) has several flaws. The assessment of coronary artery disease using fractional flow reserve (FFR) is a well-validated technique for describing lesion-level ischemia and improves clinical outcome in the context of percutaneous coronary intervention. The impact of routine FFR at the time of diagnostic CA on patient management has not been determined.

01 julio 2014

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Images and Case Reports in Interventional Cardiology. Early Aneurysm Formation After Everolimus-Eluting Stent Implantation

Mitul B. Kadakia, MD, Kelly C. Epps, MD, MS, Maureen E. Julien, CRNP, Jeffrey Ogbara, MD, Jay Giri, MD, MPH, Daniel M. Kolansky, MD, Y. Joseph Woo, MD and Robert L. Wilensky, MD

A 65-year-old woman with hypertension and dyslipidemia presented with rest chest pain in the setting of 2 mm ST depression in ECG leads V3-V6 and a troponin T level (TnT) of 0.92 ng/mL (normal, <0.08 ng/mL).

16 enero 2014

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Images and Case Reports in Interventional Cardiology. Percutaneous Bicaval Valve Implantation for Transcatheter Treatment of Tricuspid Regurgitation

Alexander Lauten, MD, Torsten Doenst, MD, Ali Hamadanchi, MD, Marcus Franz, MD and Hans R. Figulla, MD

Introduction: Severe tricuspid regurgitation (TR) frequently constitutes a high risk for surgical correction.1 For inoperable patients with TR, transcatheter caval valve implantation has been suggested.2 Herein, we report the human application and 12-month follow-up after first bicaval implantation of self- expanding valves into the superior (SVC) and inferior (IVC) vena cava as interventional concept for severe TR.3

01 abril 2015

JACC. Safety and Efficacy of the Totally Subcutaneous Implantable Defibrillator. 2-Year Results From a Pooled Analysis of the IDE Study and EFFORTLESS Registry

Martin C. Burke, DO∗; Michael R. Gold, MD, PhD†; Bradley P. Knight, MD‡; Craig S. Barr, MD§; Dominic A.M.J. Theuns, PhD‖; Lucas V.A. Boersma, MD, PhD¶; Reinoud E. Knops, MD#; Raul Weiss, MD∗∗; Angel R. Leon, MD††; John M. Herre, MD‡‡; Michael Husby, MS, MPH§§; Kenneth M. Stein, MD§§; Pier D. Lambiase, PhD

Background: The entirely subcutaneous implantable cardioverter-defibrillator (S-ICD) is the first implantable defibrillator that avoids placing electrodes in or around the heart. Two large prospective studies (IDE [S-ICD System IDE Clinical Investigation] and EFFORTLESS [Boston Scientific Post Market S-ICD Registry]) have reported 6-month to 1-year data on the S-ICD.