03 junio 2014

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Coronary Interventions. Long-Term Safety of an Everolimus-Eluting Bioresorbable Vascular Scaffold and the Cobalt-Chromium XIENCE V Stent in a Porcine Coronary Artery Model

Fumiyuki Otsuka, MD, PhD, Erica Pacheco, MS, Laura E.L. Perkins, DVM, PhD, Jennifer P. Lane, BS, Qing Wang, MD, PhD, Marika Kamberi, PhD, Michael Frie, BS, Jin Wang, PhD, Kenichi Sakakura, MD, Kazuyuki Yahagi, MD, Elena Ladich, MD, Richard J. Rapoza, PhD, Frank D. Kolodgie, PhD and Renu Virmani, MD

Background: The Absorb everolimus-eluting bioresorbable vascular scaffold (Absorb) has shown promising clinical results; however, only limited preclinical data have been published. We sought to investigate detailed pathological responses to the Absorb versus XIENCE V (XV) in a porcine coronary model with duration of implant extending from 1 to 42 months.

06 mayo 2014

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Coronary Interventions. Long-Term Clinical Outcomes After Everolimus- and Sirolimus-Eluting Coronary Stent Implantation

Hiroki Shiomi, MD, Ken Kozuma, MD, Takeshi Morimoto, MD, Keiichi Igarashi, MD, Kazushige Kadota, MD, Kengo Tanabe, MD, Yoshihiro Morino, MD, Takashi Akasaka, MD, Mitsuru Abe, MD, Satoru Suwa, MD, Toshiya Muramatsu, MD, Masakazu Kobayashi, MD, Kazuoki Dai, MD, Koichi Nakao, MD, Masaaki Uematsu, MD, Yasuhiro Tarutani, MD, Kenshi Fujii, MD, Charles A. Simonton, MD and Takeshi Kimura, MD on behalf of the RESET Investigators*

Background: Long-term clinical outcomes of everolimus-eluting stent (EES) compared with sirolimus-eluting stent (SES) have not been evaluated fully yet, especially whether EES implantation could positively affect late adverse events reported after SES implantation occurring >1 year.

10 junio 2014

STROKE. Brief Report. Modification of Outcomes With Aspirin or Apixaban in Relation to Female and Male Sex in Patients With Atrial Fibrillation. A Secondary Analysis of the AVERROES Study

Gregory Y.H. Lip, MD; John Eikelboom, MD; Salim Yusuf, MD; Olga Shestakovska, MSc; Robert G. Hart, MD; Stuart Connolly, MD; on behalf of the AVERROES Investigators

Background and Purpose: The main objective of the present analysis was to assess the effect of treatment with aspirin compared with apixaban on ischemic stroke and major bleeding in women compared with men. Female patients with atrial fibrillation are at increased stroke risk compared with male patients, and the underlying reasons for higher risk are uncertain.

01 septiembre 2015

CIRCULATION. Clinical Science. Outcomes of Patients With Acute Type B (DeBakey III) Aortic Dissection. A 13-Year, Single-Center Experience

Rana O. Afifi, MD; Harleen K. Sandhu, MD, MPH; Samuel S. Leake, BS; Mina L. Boutrous, MD; Varsha Kumar III, MS; Ali Azizzadeh, MD, FACS; Kristofer M. Charlton-Ouw, MD, FACS; Naveed U. Saqib, MD, FACS; Tom C. Nguyen, MD; Charles C. Miller III, PhD; Hazim J. Safi, MD, FACS; Anthony L Estrera, MD, FACS

Background: Aortic dissection remains the most common aortic catastrophe. In the endovascular era, the management of acute type B aortic dissection (ATBAD) is undergoing dramatic changes. The aim of this study is to evaluate the long-term outcomes of patients with ATBAD who were treated at our center over a 13-year period.

01 septiembre 2015

CIRCULATION. Clinical Science. Clinical Impact of Changes in Left Ventricular Function After Aortic Valve Replacement. Analysis From 3112 Patients

Dai Une, MD*; Laura Mesana, MSc*; Vincent Chan, MD, MPH; Michelle Maklin; Ryan Chan, BSc; Roy G. Masters, MD; Thierry G. Mesana, MD, PhD; Marc Ruel, MD, MPH

Background: Our objectives were to identify correlates of mortality and congestive heart failure after aortic valve replacement (AVR) according to preoperative left ventricular (LV) function and to describe the incidence, time course, and correlates of LV recovery and mass regression postoperatively.

19 junio 2015

CIRCULATION. Editorial. How to Stay Cool in the Intensive Care Unit? Endovascular Versus Surface Cooling

Kees H. Polderman, MD, PhD

Dozens of observational studies published over the past 2 decades have shown that fever in patients with acute neurological injury, regardless of its cause, is independently linked to higher mortality, poor neurological outcome, and increased length of stay in the intensive care unit and hospital. This has been demonstrated for traumatic brain injury, acute ischemic stroke, subarachnoid hemorrhage, intracranial hemorrhage, and cardiac arrest (CA).1,2 Therefore, therapeutic temperature management is a key goal of care in all patients with acute brain injury. In most cases the goal is strict fever control, ie, controlled normothermia; in patients with posthypoxic injuries, the goal is often to achieve below-normal core temperature, ie, to induce therapeutic hypothermia.

19 junio 2015

CIRCULATION. Resuscitation Science. Endovascular Versus External Targeted Temperature Management for Patients With Out-of-Hospital Cardiac Arrest. A Randomized, Controlled Study

Nicolas Deye, MD; Alain Cariou, MD, PhD; Patrick Girardie, MD; Nicolas Pichon, MD; Bruno Megarbane, MD, PhD; Philippe Midez, MD; Jean-Marie Tonnelier, MD; Thierry Boulain, MD; Hervé Outin, MD; Arnaud Delahaye, MD; Aurélie Cravoisy, MD; Alain Mercat, MD, PhD; Pascal Blanc, MD; Charles Santré, MD; Hervé Quintard, MD; François Brivet, MD; Julien Charpentier, MD; Delphine Garrigue, MD; Bruno Francois, MD; Jean-Pierre Quenot, MD; François Vincent, MD; Pierre-Yves Gueugniaud, MD, PhD; Jean-Paul Mira, MD, PhD; Pierre Carli, MD, PhD; Eric Vicaut, MD, PhD; Frédéric J. Baud, MD; for the Clinical and Economical Impact of Endovascular Cooling in the Management of Cardiac Arrest (ICEREA) Study Group*

Background: Targeted temperature management is recommended after out-of-hospital cardiac arrest. Whether advanced internal cooling is superior to basic external cooling remains unknown. The aim of this multicenter, controlled trial was to evaluate the benefit of endovascular versus basic surface cooling.

29 junio 2015

CIRCULATION. Epidemiology and Prevention. Trauma Exposure and Posttraumatic Stress Disorder Symptoms Predict Onset of Cardiovascular Events in Women

Jennifer A. Sumner, PhD; Laura D. Kubzansky, PhD; Mitchell S.V. Elkind, MD; Andrea L. Roberts, PhD; Jessica Agnew-Blais, ScD; Qixuan Chen, PhD; Magdalena Cerdá, DrPH; Kathryn M. Rexrode, MD; Janet W. Rich-Edwards, ScD; Donna Spiegelman, ScD; Shakira F. Suglia, ScD; Eric B. Rimm, ScD; Karestan C. Koenen, PhD

Background: Psychological stress is a proposed risk factor for cardiovascular disease (CVD), and posttraumatic stress disorder (PTSD), the sentinel stress-related mental disorder, occurs twice as frequently in women as men. However, whether PTSD contributes to CVD risk in women is not established.

14 mayo 2015

CIRCULATION. Epidemiology and Prevention. Incidence, Cause, and Comparative Frequency of Sudden Cardiac Death in National Collegiate Athletic Association Athletes. A Decade in Review

Kimberly G. Harmon, MD; Irfan M. Asif, MD; Joseph J. Maleszewski, MD; David S. Owens, MD, MS; Jordan M. Prutkin, MD, MHS; Jack C. Salerno, MD; Monica L. Zigman, MPH; Rachel Ellenbogen, MS; Ashwin L. Rao, MD; Michael J. Ackerman, MD, PhD; Jonathan A. Drezner, MD

Background: The incidence and cause of sudden cardiac death (SCD) in athletes is debated with hypertrophic cardiomyopathy often reported as the most common cause.

17 abril 2015

CIRCULATION. Interventional Cardiology. Incidence, Management, and Immediate- and Long-Term Outcomes After Iatrogenic Aortic Dissection During Diagnostic or Interventional Coronary Procedures

Iván J. Núñez-Gil, MD, PhD; Daniel Bautista, MD; Enrico Cerrato, MD; Pablo Salinas, MD, PhD; Ferdinando Varbella, MD; Pierluigi Omedè, MD; Fabrizio Ugo, MD; Alfonso Ielasi, MD; Massimo Giammaria, MD; Raúl Moreno, MD, PhD; María José Pérez-Vizcayno, MD, PhD; Javier Escaned, MD, PhD; José Alberto De Agustin, MD, PhD; Gisela Feltes, MD; Carlos Macaya, MD, PhD; Antonio Fernández-Ortiz, MD, PhD; on Behalf of the Registry on Aortic Iatrogenic Dissection (RAID) Investigators*

Background: Aortic dissection type A is a disease with high mortality. Iatrogenic aortic dissection after interventional procedures is infrequent, and prognostic data are scarce. Our objective was to analyze its incidence, patient profile, and long-term prognosis.

01 agosto 2015

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Cardiac Catheterization. Repeated Intramyocardial Bone Marrow Cell Injection in Previously Responding Patients With Refractory Angina Again Improves Myocardial Perfusion, Anginal Complaints, and Quality of Life

Imke Mann, MD*, Sander F. Rodrigo, MD*, Jan van Ramshorst, MD, PhD, Saskia L. Beeres, MD, PhD, Petra Dibbets-Schneider, MSc, Albert de Roos, MD, PhD, Ron Wolterbeek, MD, Jaap J. Zwaginga, MD, PhD, Willem E. Fibbe, MD, PhD, Jeroen J. Bax, MD, PhD, Martin J. Schalij, MD, PhD and Douwe E. Atsma, MD, PhD

Background: Intramyocardial bone marrow cell injection is associated with improvements in myocardial perfusion and anginal symptoms in patients with refractory angina pectoris. This study evaluates the effect of repeated intramyocardial bone marrow cell injection in patients with residual or recurrent myocardial ischemia.

01 agosto 2015

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Coronary Physiologic Assessment and Imaging. Impact of Aortic Valve Stenosis on Coronary Hemodynamics and the Instantaneous Effect of Transcatheter Aortic Valve Implantation

Esther M.A. Wiegerinck, MD, Tim P. van de Hoef, MD, PhD, M. Cristina Rolandi, PhD, ZeYie Yong, MD, PhD, Floortje van Kesteren, MD, Karel T. Koch, MD, PhD, Marije M. Vis, MD, PhD, Bas A.J.M. de Mol, MD, PhD, Jan J. Piek, MD, PhD and Jan Baan Jr, MD, PhD

Background: Aortic valve stenosis (AS) induces compensatory alterations in left ventricular hemodynamics, leading to physiological and pathological alterations in coronary hemodynamics. Relief of AS by transcatheter aortic valve implantation (TAVI) decreases ventricular afterload and is expected to improve microvascular function immediately. We evaluated the effect of AS on coronary hemodynamics and the immediate effect of TAVI.

01 agosto 2015

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Coronary Artery Disease. Everolimus Eluting Stents Versus Coronary Artery Bypass Graft Surgery for Patients With Diabetes Mellitus and Multivessel Disease

Sripal Bangalore, MD, MHA, Yu Guo, MA, Zaza Samadashvili, MD, Saul Blecker, MD, MHS, Jinfeng Xu, PhD and Edward L. Hannan, PhD, MS

Background: In patients with diabetes mellitus and multivessel disease, coronary artery bypass graft surgery and percutaneous coronary intervention are treatment options. However, there is paucity of data comparing coronary artery bypass graft surgery against newer generation stents.

01 agosto 2015

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Coronary Interventions. Clinical Impact of Intravascular Ultrasound–Guided Chronic Total Occlusion Intervention With Zotarolimus-Eluting Versus Biolimus-Eluting Stent Implantation

Byeong-Keuk Kim, MD, Dong-Ho Shin, MD, Myeong-Ki Hong, MD, Hun Sik Park, MD, Seung-Woon Rha, MD, Gary S. Mintz, MD, Jung-Sun Kim, MD, Je Sang Kim, MD, Seung-Jin Lee, MD, Hee-Yeol Kim, MD, Bum-Kee Hong, MD, Woong-Chol Kang, MD, Jin-Ho Choi, MD and Yangsoo Jang, MD; for the CTO-IVUS Study Investigators*

Background: There have been no randomized studies comparing intravascular ultrasound (IVUS)–guided versus conventional angiography–guided chronic total occlusion (CTO) intervention using new-generation drug-eluting stent Therefore, we conducted a prospective, randomized, multicenter trial designed to test the hypothesis that IVUS-guided CTO intervention is superior to angiography-guided intervention.

01 agosto 2015

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Structural Heart Disease. Routine Screening of Coronary Artery Disease With Computed Tomographic Coronary Angiography in Place of Invasive Coronary Angiography in Patients Undergoing Transcatheter Aortic Valve Replacement

Alaide Chieffo, MD*, Gennaro Giustino, MD*, Pietro Spagnolo, MD, Vasileios F. Panoulas, MD, PhD, Matteo Montorfano, MD, Azeem Latib, MD, Filippo Figini, MD, Eustachio Agricola, MD, Chiara Gerli, MD, Annalisa Franco, MD, Manuela Giglio, MD, Micaela Cioni, MD, Ottavio Alfieri, MD, Paolo Guido Camici, MD and Antonio Colombo, MD

Background: Coronary artery disease (CAD) screening is required before transcatheter aortic valve implantation (TAVR). Although invasive coronary angiography (CA) remains the gold standard for CAD assessment, computed tomographic CA (CTCA) could be a safe and effective noninvasive alternative for CAD screening in patients undergoing TAVR.