29 junio 2014

CIRCULATION. Epidemiology and Prevention. 30-Year Mortality After Venous Thromboembolism

Kirstine Kobberøe Søgaard, MD; Morten Schmidt, MD; Lars Pedersen, PhD; Erzsébet Horváth–Puhó, PhD; Henrik Toft Sørensen, DMSc

Background: Studies on long-term mortality after venous thromboembolism (VTE) are sparse.

11 julio 2014

CIRCULATION. Health Services and Outcomes Research. Cost-Effectiveness of Follow-Up of Pulmonary Nodules Incidentally Detected on Cardiac Computed Tomographic Angiography in Patients With Suspected Coronary Artery Disease

Alexander Goehler, MD, PhD, MSc, MPH; Pamela M. McMahon, PhD; Heidi S. Lumish, BS; Carol C. Wu, MD; Vidit Munshi, BS; Michael Gilmore, MBA; Jonathan H. Chung, MD; Brian B. Ghoshhajra, MD, MBA; Daniel Mark, MD; Quynh A. Truong, MD, MPH; G. Scott Gazelle, MD, MPH, PHD; Udo Hoffmann, MD, MPH

Background: Pulmonary nodules (PNs) are often detected incidentally during coronary computed tomographic (CT) angiography, which is increasingly being used to evaluate patients with chest pain symptoms. However, the efficiency of following up on incidentally detected PN is unknown.

09 mayo 2014

CIRCULATION. Stroke. Evaluation of Interval Times From Onset to Reperfusion in Patients Undergoing Endovascular Therapy in the Interventional Management of Stroke III Trial

Mayank Goyal, MD; Mohammed A. Almekhlafi, MD, MSc; Liqiong Fan, MS; Bijoy K. Menon, MD; Andrew M. Demchuk, MD; Sharon D. Yeatts, PhD; Michael D. Hill, MD, MSc; Thomas Tomsick, MD; Pooja Khatri, MD, MSc; Osama O. Zaidat, MD; Edward C. Jauch, MD; Muneer Eesa, MD; Tudor G. Jovin, MD; Joseph P. Broderick, MD

Background: Meaningful delays occurred in the Interventional Management of Stroke (IMS) III trial. Analysis of the work flow will identify factors contributing to the in-hospital delays.

21 agosto 2015

JOURNAL OF THE AMERICAN HEART ASSOCIATION. Coronary Heart Disease. Prognostic Value of Coronary Computed Tomography (CT) Angiography and Coronary Artery Calcium Score Performed Before Revascularization

Shinichiro Fujimoto, MD, PhD12; Takeshi Kondo, MD, PhD2; Kanako K. Kumamaru, MD, PhD3; Tomohiro Shinozaki, MPH4; Kazuhisa Takamura, MD, PhD12; Yuko Kawaguchi, MD1; Rie Matsumori, MD, PhD1; Makoto Hiki, MD, PhD1; Katsumi Miyauchi, MD, PhD1; Hiroyuki Daida, MD, PhD1; Frank J. Rybicki, MD, PhD3

Backgroun: Cardiac events after revascularization are equally attributable to recurrence at site of culprit lesions and development of nonculprit lesions. We evaluated the hypothesis that coronary computed tomography (CT) angiography and coronary artery calcium score (CACS) performed before revascularization predicts cardiac events after treatment.

29 julio 2015

JOURNAL OF THE AMERICAN HEART ASSOCIATION. Interventional Cardiology. Hypothyroidism Is Associated With Coronary Endothelial Dysfunction in Women

Jaskanwal D. Sara, MBChB1; Ming Zhang, MD1; Hossein Gharib, MD2; Lilach O. Lerman, MD, PhD3; Amir Lerman, MD1

Background: Hypothyroidism is associated with an increased risk of coronary artery disease, beyond that which can be explained by its association with conventional cardiovascular risk factors. Coronary endothelial dysfunction precedes atherosclerosis, has been linked to adverse cardiovascular events, and may account for some of the increased risk in patients with hypothyroidism. The aim of this study was to determine whether there is an association between epicardial and microvascular coronary endothelial dysfunction and hypothyroidism.

01 julio 2015

JACC: CARDIOVASCULAR INTERVENTIONS. “Virtual” (Computed) Fractional Flow Reserve. Current Challenges and Limitations

Paul D. Morris, MBChB∗; Frans N. van de Vosse, PhD‡; Patricia V. Lawford, PhD∗; D. Rodney Hose, PhD∗; Julian P. Gunn, MD∗

Fractional flow reserve (FFR) is the “gold standard” for assessing the physiological significance of coronary artery disease during invasive coronary angiography. FFR-guided percutaneous coronary intervention improves patient outcomes and reduces stent insertion and cost; yet, due to several practical and operator related factors, it is used in <10% of percutaneous coronary intervention procedures.

01 julio 2015

JACC: CARDIOVASCULAR INTERVENTIONS. Repeatability of Fractional Flow Reserve Despite Variations in Systemic and Coronary Hemodynamics

Nils P. Johnson, MD, MS∗; Daniel T. Johnson, MSc∗; Richard L. Kirkeeide, PhD∗; Colin Berry, MB ChB, PhD†; Bernard De Bruyne, MD, PhD§; William F. Fearon, MD‖; Keith G. Oldroyd, MB ChB, MD‡; Nico H.J. Pijls, MD, PhD¶; K. Lance Gould, MD∗

Objectives: This study classified and quantified the variation in fractional flow reserve (FFR) due to fluctuations in systemic and coronary hemodynamics during intravenous adenosine infusion.

01 septiembre 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Fluoroscopic Anatomy of Left-Sided Heart Structures for Transcatheter Interventions. Insight From Multislice Computed Tomography

Pascal Thériault-Lauzier, PhD∗; Ali Andalib, MD∗; Giuseppe Martucci, MD∗; Darren Mylotte, MD∗; Renzo Cecere, MD†; Rüediger Lange, MD, PhD‡; Didier Tchétché, MD§; Thomas Modine, MD, PhD‖; Nicolas van Mieghem, MD¶; Stephan Windecker, MD#; Jean Buithieu, MD∗; Nicolo Piazza, MD, PhD∗

With the introduction of transcatheter structural heart therapies, cardiologists are increasingly aware of the importance of understanding anatomical details of left-sided heart structures. Understanding fluoroscopic cardiac anatomy can facilitate optimal positioning and deployment of prostheses during transcatheter valve repair/replacement, left atrial appendage occlusion, septal defect closure, and paravalvular leak closure. It is possible to use multislice computed tomography to determine optimal fluoroscopic viewing angles for such transcatheter therapies. The purpose of this paper is to describe how optimal fluoroscopic viewing angles of left-sided heart structures can be obtained using computed tomography. Two- and 3-chamber views are described and may become standard in the context of transcatheter structural heart interventions.

01 septiembre 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Mechanisms of Atherothrombosis and Vascular Response to Primary Percutaneous Coronary Intervention in Women Versus Men With Acute Myocardial Infarction. Results of the OCTAVIA Study

Giulio Guagliumi, MD∗; Davide Capodanno, MD, PhD†; Francesco Saia, MD‡; Giuseppe Musumeci, MD∗; Giuseppe Tarantini, MD§; Roberto Garbo, MD‖; Gabriele Tumminello, MD¶; Vasile Sirbu, MD∗; Micol Coccato, MD∗; Massimo Fineschi, MD#; Carlo Trani, MD∗∗; Mauro De Benedictis, MD††; Ugo Limbruno, MD‡‡; Leonardo De Luca, MD§§; Giampaolo Niccoli, MD‖‖; Hiram Bezerra, MD¶¶; Elena Ladich, MD##; Marco Costa, MD¶¶; Giuseppe Biondi Zoccai, MD∗∗∗; Renu Virmani, MD##

Objectives: This study sought to assess in vivo sex differences in the pathophysiology of ST-segment elevation myocardial infarction (STEMI) and vascular response to primary percutaneous coronary intervention (PCI).

01 septiembre 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Outcomes After Emergency Percutaneous Coronary Intervention in Patients With Unprotected Left Main Stem Occlusion. The BCIS National Audit of Percutaneous Coronary Intervention 6-Year Experience

Niket Patel, MBBS, BSc∗; Giovanni Luigi De Maria, MD∗; George Kassimis, MD, MSc, PhD∗; Kazem Rahimi, DM, MPH∗; Derrick Bennett, PhD‡; Peter Ludman, MBBChir, MD§; Adrian P. Banning, MBBS, MD∗

Objectives: This study sought to evaluate in-hospital outcomes and 3-year mortality of patients presenting with unprotected left main stem occlusion (ULMSO) treated with primary percutaneous coronary intervention (PPCI).

01 septiembre 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Outcomes of Primary Percutaneous Coronary Intervention in ST-Segment Elevation Myocardial Infarction Patients With Previous Coronary Bypass Surgery

Louis P. Kohl, MD∗; Ross F. Garberich, MS∗; Hannah Yang, BS∗; Scott W. Sharkey, MD∗; M. Nicholas Burke, MD∗; Daniel L. Lips, MD∗; David A. Hildebrandt, RN∗; David M. Larson, MD∗; Timothy D. Henry, MD∗

Objectives: This study sought to determine the contemporary clinical characteristics and outcomes of patients with ST-segment elevation myocardial infarction (STEMI) and previous coronary artery bypass graft (CABG), including those with a saphenous vein graft culprit lesion.

01 septiembre 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Real-Time Assessment of Myocardial Viability in the Catheterization Laboratory Using the Intracoronary Electrograms Recorded by the PTCA Guidewire in Patients With Left Ventricular Dysfunction

Ettore Petrucci, MD∗; Vruyr Balian, MD∗; Andrea Bocchieri, PhD†

Objectives: This study aimed to determine whether the intracoronary electrograms (IC-EGMs) recorded using a standard percutaneous coronary intervention guidewire could provide myocardial viability information.

01 septiembre 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Appropriateness Ratings of Percutaneous Coronary Intervention in Japan and Its Association With the Trend of Noninvasive Testing

Taku Inohara, MD∗; Shun Kohsaka, MD, PhD∗; Hiroaki Miyata, PhD†; Ikuko Ueda, PhD∗; Shiro Ishikawa, MD, PhD‡; Takahiro Ohki, MD, PhD§; Yutaro Nishi, MD‖; Kentaro Hayashida, MD, PhD∗; Yuichiro Maekawa, MD, PhD∗; Akio Kawamura, MD, PhD∗; Takahiro Higashi, MD, PhD¶; Keiichi Fukuda, MD, PhD∗

Objectives: The aim of this study was to evaluate the appropriateness of percutaneous coronary intervention (PCI) in Japan and clarify the association between trends of pre-procedural noninvasive testing and changes in appropriateness ratings.

01 septiembre 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Impact of Balloon Post-Dilation on Clinical Outcomes After Transcatheter Aortic Valve Replacement With the Self-Expanding CoreValve Prosthesis

Marco Barbanti, MD∗; Anna Sonia Petronio, MD‡; Davide Capodanno, MD, PhD∗; Federica Ettori, MD§; Antonio Colombo, MD‖; Francesco Bedogni, MD¶; Federico De Marco, MD#; Marco De Carlo, MD‡; Claudia Fiorina, MD§; Azeem Latib, MD‖; Luca Testa, MD¶; Giuseppe Bruschi, MD#; Arnaldo Poli, MD∗∗; Cristina Giannini, MD‡; Salvatore Curello, MD§; Diego Maffeo, MD§; Carmelo Sgroi, MD∗; Paola Martina, MD∗∗; Simona Gulino, MD∗; Martina Patanè, MD∗; Yohei Ohno, MD∗; Guilherme F. Attizzani, MD∗; Sebastiano Immè, MD∗; Stefano Cannata, MD∗; Alessandra Gentili, MS††; Agnese Rossi, MS‡‡; Corrado Tamburino, MD, PhD∗

Objectives: The aim of this study was to assess the incidence and clinical impact of balloon post-dilation (BPD) after transcatheter aortic valve replacement (TAVR) with the CoreValve prosthesis (Medtronic Inc., Minneapolis, Minnesota).

22 julio 2014

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Myocardial Infarction. Defining the Optimal Cardiac Troponin T Threshold for Predicting Death Caused by Periprocedural Myocardial Infarction After Percutaneous Coronary Intervention

Joerg Herrmann, MD, Ryan J. Lennon, MS, Allan S. Jaffe, MD, David R. Holmes Jr, MD, Charanjit S. Rihal, MD and Abhiram Prasad, MD

Background: There is controversy about the diagnostic and prognostic significance of percutaneous coronary intervention–related myocardial infarction, especially with the use of cardiac troponin T (cTnT). This analysis was designed to address the question of the presence and the level of a prognostic cTnT threshold.