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ESTUDIOS


01 enero 2017

JACC: CARDIOVASCULAR INTERVENTIONS. Culprit Vessel Versus Multivessel Versus In-Hospital Staged Intervention for Patients With ST-Segment Elevation Myocardial Infarction and Multivessel Disease. Stratified Analyses in High-Risk Patient Groups and Anatomic Subsets of Nonculprit Disease

M. Bilal Iqbal, Imad J. Nadra, Lillian Ding, Anthony Fung, Eve Aymong, Albert W. Chan, Steven Hodge, Anthony Della Siega, Simon D. Robinson, British Columbia Cardiac Registry Investigators

Objective: This study evaluated revascularization strategies for patients with ST-segment elevation myocardial infarction (STEMI) and multivessel disease.

01 enero 2017

JACC: CARDIOVASCULAR INTERVENTIONS. Efficacy and Safety of the Absorb Everolimus-Eluting Bioresorbable Scaffold for Treatment of Patients With Diabetes Mellitus. Results of the Absorb Diabetic Substudy

Dean J. Kereiakes, Stephen G. Ellis, Takeshi Kimura, Alexandre Abizaid, Weiying Zhao, Susan Veldhof, Minh-Thien Vu, Zhen Zhang, Yoshinobu Onuma, Bernard Chevalier, Patrick W. Serruys, Gregg W. Stone

Objectives: The study sought to evaluate the efficacy and safety of the Absorb everolimus-eluting bioresorbable vascular scaffold (BVS) (Abbott Vascular, Abbott Park, Illinois) in patients with diabetes mellitus.

01 enero 2017

JACC: CARDIOVASCULAR INTERVENTIONS. Transcatheter Valve-in-Ring Implantation for the Treatment of Residual or Recurrent Tricuspid Valve Dysfunction After Prior Surgical Repair

Jamil Aboulhosn, Allison K. Cabalka, Daniel S. Levi, Dominique Himbert, Luca Testa, Azeem Latib, Raj R. Makkar, Younes Boudjemline, Dennis W. Kim, Joelle Kefer, Sabine Bleiziffer, Gunter Kerst, Danny Dvir, Doff B. McElhinney

Objectives: This study sought to describe the results of transcatheter tricuspid valve-in-ring (TVIR) implantation for treatment of tricuspid regurgitation (TR).

01 enero 2017

JACC: CARDIOVASCULAR INTERVENTIONS. Percutaneous Pulmonary Embolus Mechanical Thrombectomy

Deepali Nivas Tukaye, Michael McDaniel, Henry Liberman, Yelena Burkin, Wissam Jaber

A 66-year-old African-American woman with no significant medical history presented with a 2-day history of worsening exertional dyspnea with minimal activity. Pulmonary embolus (PE) was suspected on the basis of clinical presentation and elevated D-dimer levels in absence of other clear explanation for her symptoms. Computed tomography of the chest revealed extensive, acute bilateral pulmonary embolus with significant clot burden in the right main pulmonary artery (PA). There was evidence of right heart strain with right ventricular (RV) dilation (elevated troponin [0.39 ng/ml] and brain natriuretic peptide [187 pg/ml]; right ventricle/left ventricle ratio 1.17 on computed tomography). Transthoracic echocardiography confirmed moderate RV dilation and systolic dysfunction. The patient’s estimated RV systolic pressure was 71 mm Hg. She was hemodynamically stable at admission, with normal blood pressure and heart rate and oxygen saturation >90% on room air. Given her hemodynamic stability and on the basis of the patient’s own preference, she was started on intravenous heparin and conservative management.

01 enero 2017

JACC: CARDIOVASCULAR INTERVENTIONS. Coronary Artery Aneurysm After Bioresorbable Vascular Scaffold Implantation With Post-Dilation. Is Less More?

Felix Meincke, Claudia Reinholz, Tobias Spangenberg, Hendrik Wienemann, Aref Arjomand, Felix Kreidel, Karl-Heinz Kuck, Alexander Ghanem

A 33-year-old man underwent routine percutaneous coronary intervention for a left anterior descending artery stenosis (fractional flow reserve 0.79) (Figure 1A). After stepwise pre-dilation up to 3.0 mm, a 3.5 × 28-mm Novolimus-eluting bioresorbable vascular scaffold (NE-BVS) (Elixir Medical, Sunnyvale, California) was implanted followed by post-dilation up to a 4.0-mm noncompliant balloon due to initial angiographically insufficient stent deployment (Figure 1B). Six months after implantation, routine angiography revealed a large aneurysm at the site of prior BVS implantation (Figure 1C, Online Video 1). Given the rapidness of development with a subsequent high danger of rupture, the decision was made for percutaneous treatment.

01 enero 2017

JACC: CARDIOVASCULAR INTERVENTIONS. Successful Retrieval of a Dislodged Left Atrial Appendage Closure Device

Oh-Hyun Lee, Hancheol Lee, Jung-Sun Kim

A 70-year-old man with persistent atrial fibrillation was referred for percutaneous left atrial appendage occlusion. Because of a high cardioembolic stroke risk (with a CHA2DS2-VASc score of 3 points) and given his previous history of gastric bleeding during anticoagulation treatment, we decided to perform left atrial appendage closure. We successfully deployed a 28-mm AMPLATZER Cardiac Plug (ACP) (St. Jude Medical, Minneapolis, Minnesota) device

01 enero 2017

JACC: CARDIOVASCULAR INTERVENTIONS. Guidewire Self-Extrusion After Entrapment of Distal Protection Device During Saphenous Vein Graft Angioplasty

Rodrigo Vugman Wainstein, Felipe Homem Valle, Fernando Pivatto Júnior, Ivan Morzoletto Pedrollo, Luiz Carlos Corsetti Bergoli, Marco Vugman Wainstein

A 66-year-old man with previous coronary artery bypass graft surgery was referred to cardiac catheterization due to a non–ST-segment elevation acute myocardial infarction. On arrival he was hemodynamically stable and complaining of mild chest discomfort. Coronary angiography showed a patent saphenous vein graft (SVG) to distal right coronary artery with severe stenosis in the proximal and midsegment (Figure 1A). The choice for percutaneous coronary intervention was made.

01 enero 2017

JACC: CARDIOVASCULAR INTERVENTIONS. The ReACT Trial. Randomized Evaluation of Routine Follow-up Coronary Angiography After Percutaneous Coronary Intervention Trial

Hiroki Shiomi, Takeshi Morimoto, Shoji Kitaguchi, Yoshihisa Nakagawa, Katsuhisa Ishii, Yoshisumi Haruna, Itaru Takamisawa, Makoto Motooka, Kazuhiro Nakao, Shintaro Matsuda, Satoru Mimoto, Yutaka Aoyama, Teruki Takeda, Koichiro Murata, Masaharu Akao, Tsukasa Inada, Hiroshi Eizawa, Eiji Hyakuna, Kojiro Awano, Manabu Shirotani, Yutaka Furukawa, Kazushige Kadota, Katsumi Miyauchi, Masaru Tanaka, Yuichi Noguchi, Sunao Nakamura, Satoshi Yasuda, Shunichi Miyazaki, Hiroyuki Daida, Kazuo Kimura, Yuji Ikari, Haruo Hirayama, Tetsuya Sumiyoshi, Takeshi Kimura, ReACT Investigators, Kazuo Kimura, Kiyoshi Hibi, Katsuhisa Ishii, Kazuaki Kataoka, Takeshi Kimura, Hiroki Shiomi, Manabu Shirotani, Shunichi Miyazaki, Teruki Takeda, Satoshi Yasuda, Kazuhiro Nakao, Masaharu Akao, Mitsuru Ishii, Eiji Momona, Tetsuya Sumiyoshi, Itaru Takamisawa, Hiroyuki Daida, Katsumi Miyauchi, Satoru Mimoto, Sunao Nakamura, Yutaka Furukawa, Shintaro Matsuda, Hiroshi Eizawa, Akinori Takizawa, Koichiro Murata, Masaru Tanaka, Tsukasa Inada, Yuichi Noguchi, Yoshihisa Nakagawa, Makoto Motooka, Yuji Ikari, Kojiro Awano, Yoshisumi Haruna, Shoji Kitaguchi, Haruo Hirayama, Mamoru Nanasato

Objectives: The purpose of this study was to evaluate long-term clinical impact of routine follow-up coronary angiography (FUCAG) after percutaneous coronary intervention (PCI) in daily clinical practice in Japan.

01 enero 2017

JACC: CARDIOVASCULAR INTERVENTIONS. Randomized Comparison of Oral P2Y12-Receptor Inhibitor Loading Strategies for Transitioning From Cangrelor. The ExcelsiorLOAD2 Trial

Willibald Hochholzer, Pascal Kleiner, Iris Younas, Christian M. Valina, Nikolaus Löffelhardt, Michael Amann, Timo Bömicke, Miroslaw Ferenc, Dieter Hauschke, Dietmar Trenk, Franz-Josef Neumann, Christian Stratz

Objectives: This randomized trial tested whether early loading with prasugrel can provide sufficient platelet inhibition even when given at the start of a 2-h infusion of cangrelor.

01 enero 2017

JACC: CARDIOVASCULAR INTERVENTIONS. Randomized Multicenter Trial Investigating Angiographic Outcomes of Hybrid Sirolimus-Eluting Stents With Biodegradable Polymer Compared With Everolimus-Eluting Stents With Durable Polymer in Chronic Total Occlusions. The PRISON IV Trial

Koen Teeuwen, René J. van der Schaaf, Tom Adriaenssens, Jacques J. Koolen, Pieter C. Smits, José P.S. Henriques, Paul H.M.J. Vermeersch, R. Melvyn Tjon Joe Gin, Bastiaan E. Schölzel, Johannes C. Kelder, Jan G.P. Tijssen, Pierfrancesco Agostoni, Maarten J. Suttorp

Objectives: The aim of this study was to investigate the efficacy and safety of the hybrid ultrathin-strut sirolimus-eluting stent (SES) with biodegradable polymer compared with the thin-strut everolimus-eluting stent (EES) with durable polymer in successfully recanalized chronic total occlusions (CTOs).

01 enero 2017

JACC: CARDIOVASCULAR INTERVENTIONS. First-in-Human Evaluation of a Novel Polymer-Free Drug-Filled Stent. Angiographic, IVUS, OCT, and Clinical Outcomes From the RevElution Study

Stephen G. Worthley, Alexandre Abizaid, Ajay J. Kirtane, Daniel I. Simon, Stephan Windecker, Sandeep Brar, Ian T. Meredith, Sharad Shetty, Ajay Sinhal, Alexandra Popma Almonacid, Daniel Chamié, Akiko Maehara, Gregg W. Stone, RevElution Investigators, Stephen Worthley, Sharad Shetty, Ajay Sinhal, Ian Meredith, Alexandre Abizaid, Nigel Jepson, Ravinay Bhindi, Soo Teik Lim, Peter Stewart, Peter Barlis, Darren Walters, David Muller, Stephen Cox, Rohan Bhagwandeen

Objectives: This study sought to assess the safety and effectiveness of the drug-filled stent (DFS) (Medtronic, Santa Rosa, California) in the treatment of patients with coronary artery disease.

01 enero 2017

JACC: CARDIOVASCULAR INTERVENTIONS. 9-Month Clinical and Angiographic Outcomes of the COBRA Polyzene-F NanoCoated Coronary Stent System

Donald E. Cutlip, Kirk N. Garratt, Victor Novack, Mark Barakat, Perwaiz Meraj, Luc Maillard, Andrejs Erglis, Rajiv Jauhar, Jeffrey J. Popma, Robert Stoler, Sigmund Silber, PzF SHIELD Trial Investigators, Donald Cutlip, Suhail Allaqaband, Ronald Caputo, Nirat Beohar, David Brown, Kirk Garratt, Rajiv Jauhar, Jon George, Vincent Varghese, Mark Huth, German Larrain, Tommy Lee, Amir Malik, Scott Martin, Thomas McGarry, Charles Phillips, Alpesh Shah, Robert Stoler, Michael Ball, R. Jeffrey Price, Joseph Rossi, Charles Taylor, Thaddeus Tolleson, William Nicholson, Srinivas Kesanakurthy, Mohammad Shoukfeh, Aloke Finn, Chandanreddy Devireddy, Charles Shoultz, Mark Robbins, Radoslaw Kiesz, Pramod Menon, Daniel Weilenmann, Horst Sievert, Andrejs Erglis, Goran Stankovic, Jacques Berland, Nicolas Delarche, Jean Lou Hirsch, Luc Maillard, John Shayne, Antonio Serra, Antonio Fernandez-Ortiz, Jean-Pierre Monassier, Sigmund Silber

Objectives: The aim of this study was to assess the safety and effectiveness of the COBRA Polyzene-F NanoCoated Coronary Stent System (CeloNova Biosciences, San Antonio, Texas) for the treatment of de novo coronary artery lesions.

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