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ESTUDIOS


15 junio 2021

Intravascular Lithotripsy for Peripheral Artery Calcification: 30-Day Outcomes From the Randomized Disrupt PAD III Trial

Gunnar Tepe, Marianne Brodmann, Martin Werner, William Bachinsky, Andrew Holden, Thomas Zeller, Sarang Mangalmurti, Claus Nolte-Ernsting, Barry Bertolet, Dierk Scheinert, William A. Gray, and for the Disrupt PAD III Investigators

Objectives The study sought to compare short-term outcomes in patients with femoropopliteal artery calcification receiving vessel preparation with intravascular lithotripsy (IVL) or percutaneous transluminal angioplasty (PTA) prior to drug-coated balloon (DCB) for symptomatic peripheral artery disease.

15 junio 2021

Randomized Trial Comparing Standard Versus Ultrasound-Assisted Thrombolysis for Submassive Pulmonary Embolism: The SUNSET sPE Trial

Efthymios D. Avgerinos, Wissam Jaber, Joan Lacomis, Kyle Markel, Michael McDaniel, Belinda N. Rivera-Lebron, Charles B. Ross, Jacob Sechrist, Catalin Toma, Rabih Chaer, and on behalf of SUNSET sPE Collaborators

Objectives The aim of this trial was to determine whether ultrasound-assisted thrombolysis (USAT) is superior to standard catheter-directed thrombolysis (SCDT) in pulmonary arterial thrombus reduction for patients with submassive pulmonary embolism (sPE).

15 junio 2021

OCT Guidance for Detection and Treatment of Free-Floating Struts Following Ostial LAD Stenting

Dejan Milasinovic, Miloje Tomasevic, Vladan Vukcevic, and Goran Stankovic

Percutaneous coronary intervention (PCI) involving the ostial left anterior descending coronary artery (LAD) bears an inherent risk for excessive stent strut protrusion into the distal left main coronary artery (LM), thus potentially creating an area of significant stent malapposition and/or underexpansion, which have been associated with the occurrence of stent thrombosis (1).

15 julio 2021

A Giant Pseudoaneurysm Due to Coronary Rupture Caused by Stent Separation Following Percutaneous Coronary Intervention

Shuichi Kegai, Hiroshi Akanuma, and Yuichi Katagiri

Coronary angiography in a 76-year-old woman hospitalized for congestive heart failure revealed severe stenosis and calcification in the mid right coronary artery (Figure 1A). High-pressure expansion using a noncompliant balloon was repeatedly performed for the severely calcified lesion. After balloon dilatation, we deployed 2 overlapping zotarolimus-eluting stents (3.0 × 26 mm and 3.0 × 30 mm; Resolute onyx, Medtronic Vascular, Inc., Galway, Ireland). The overlapping stent struts were located at the site of hinge motion. Finally, percutaneous intervention was completed, establishing a thrombolysis in myocardial infarction grade 3 flow

15 julio 2021

Intravascular Ultrasound Imaging and Endovascular Treatment of Left Ventricle Assist Device (HM3) Outflow Graft Obstruction

Luca Apruzzi, Savino Altizio, Diletta Loschi, Luca Bertoglio, Americo Peña, Silvia Ajello, Alberto Zangrillo, and Anna Mara Scandroglio

A 74-year-old man, who 4 years before had received a left ventricular assist device (LVAD) HeartMate3 (Abbott Laboratories, Lake Bluff, Illinois) for post-ischemic end-stage heart failure, was emergently readmitted for acute heart failure, pulmonary edema and acute renal failure. Log-file LVAD analysis demonstrated no alarms generated from the pump, and a flow of 3.9 l/min (5,300 rpm). Computed tomography angiography (CTA) demonstrated obstruction of the outflow graft (OG) (Figures 1A to 1C). An endovascular treatment was planned and an intravascular ultrasound (IVUS) study (Visions PV 0.035, Volcano Corporation; Rancho Cordova, California) was obtained. The imaging confirmed a 75% cross-section lumen area reduction due to external compression between the strain relief and the Dacron graft resulting in OG infolding (Figures 1D to 1F). The obstruction was treated with a covered stent-grafting (BE Graft 14 × 48 mm, Bentley InnoMed, Hechingen, Germany) and noncompliant balloon post-dilation (Atlas Gold 16 × 60 mm, BARD Peripheral Vascular, Tempe, Arizona) (Video 1). The procedure was uneventful and performed without the use of contrast medium. Both intraoperative IVUS (Figures 2D to 2F) and post-operative control CTA (Figures 2A to 2C) confirmed the resolution of OG obstruction.

15 julio 2021

Rescue Coilization for Spontaneous Coronary Artery Rupture

Shih-Tsung Cheng, Chih-Jen Liu, Hsuan-Li Huang, and Yu-Lin Ko

In the era of percutaneous coronary intervention (PCI), coronary artery perforation is not uncommon; however, acute spontaneous coronary artery rupture (SCAR) without known etiology is a rare condition that clinicians should have greater awareness for the prevention of catastrophic cardiac tamponade (1). A 68-year-old man received successful PCI for troponin-I–elevated acute coronary syndrome over the left anterior descending artery and left circumflex artery with drug-eluting stents (Video 1). Three hours post-intervention, recurrent chest pain was reported along with shock, requiring emergency pericardiocentesis for acute cardiac tamponade. Repeat angiography unexpectedly revealed that the initially mildly diseased and nonintervened right coronary artery (Figure 1A, Video 2) developed SCAR in multiple terminal branches (Figure 1B, Video 3). Repeat pericardiocentesis of bloody effusion, fluid resuscitation, and balloon occlusion for coronary extravasation failed to stabilize the patient. The extravasation was finally sealed by embolization with multiple coils (Figure 1C, Video 4). In the following days, extracorporeal membrane oxygenation was successfully employed to rescue the patient from a potentially complicated clinical course including cardiac arrest, right ventricular global hypokinesia, and frank pulmonary edema. The patient was discharged 27 days later and is in favorable general health at the 5-month follow-up.

15 julio 2021

Not the Expected Coronary Complication!

Marouane Boukhris, Jessica Forcillo, Jeannot Potvin, Maxime Robert-Halabi, Jean-François Gobeil, and Jean-Bernard Masson

A 78-year-old woman with exertional dyspnea was diagnosed with critical aortic stenosis and single-vessel mild left anterior descending coronary artery (LAD) disease in a left dominant system. Multidetector computed tomography showed that left main coronary artery (LM) height (11 mm) and sinotubular junction (13.8 mm) were relatively low (Figure 1, Video 1). Virtual transcatheter heart valve (THV) to coronary distance was 4.9 mm.

15 julio 2021

Thrombosis-Related Honeycomb-Like Structure in Non-Infarct-Related Artery in a COVID-19 Convalescent Patient Presenting With STEMI

Pawel Gasior, Krzysztof Bryniarski, Andrzej Ochala, and Wojciech Wojakowski

A 59-year-old woman with no history of coronary artery disease and a history of heavy smoking, recently recovered (4 weeks previously) from a mild course of ambulatory treated coronavirus disease-2019 (COVID-19), was admitted to our clinic with the diagnosis of anterior wall ST-segment elevation myocardial infarction.

15 julio 2021

“Pressure Pressing Down on Me”: Importance of Intracoronary Physiology and Inotropic Challenge for Myocardial Bridge

Paolo Boretto, Alessandro Depaoli, Federico Conrotto, Pierluigi Omedè, Ovidio De Filippo, Alessandro Serafini, Giulio Antonino Strazzarino, Paolo Fonio, Gaetano Maria De Ferrari, and Fabrizio D’Ascenzo

A 66-year-old otherwise healthy woman was admitted to the cardiology department for exercise-induced dyspnea and positive stress electrocardiogram with anterior ST-segment depression. A coronary computed tomography showed an 18-mm-long myocardial bridge (MB) in mid left anterior descending artery with deep encasement (3.9 mm) (Figure 1) (1), without other significant stenosis. At coronary angiography MB was confirmed, although hard to be seen (Figure 2). Functional assessment with instantaneous wave-free ratio (iFR) was obtained showing baseline diastolic flow limitation (iFR 0.86) (Figure 3). After infusion of nitrates, a dobutamine challenge was performed to further assess hemodynamic relevance. During a 5 μg/kg/min dobutamine infusion, iFR further reduced to 0.72 (Figure 4). Because no significant coronary stenosis was detected, the patient was discharged with calcium-channel blocker with complete resolution of symptoms at 3-month follow-up visit.

15 julio 2021

Anatomic Approach to Transseptal Puncture for Structural Heart Interventions

Trevor Simard, Abdallah El Sabbagh, Colleen Lane, Ammar M. Killu, Mohamad Alkhouli, Peter M. Pollak, Jeremy J. Thaden, Mackram F. Eleid, Paul A. Friedman, and Charanjit S. Rihal

The use of transseptal puncture continues to rise given the increase in left atrial cardiac interventions. The authors review an anatomic approach to transseptal puncture incorporating multimodality imaging both pre- and intraprocedurally with stepwise escalation algorithms to ensure safe and efficacious large-bore transseptal puncture

15 julio 2021

Validation of Prosthetic Mitral Regurgitation Quantification Using Novel Angiographic Platform by Mock Circulation

Hideyuki Kawashima, Patrick W. Serruys, Rodrigo Modolo, Michele Pighi, Rutao Wang, Masafumi Ono, Jean-Paul Aben, Chun Chin Chang, Hadewych Van Hauwermeiren, Bill Brunnett, Martijn Cox, Liesbeth Rosseel, Darren Mylotte, Philippe Pibarot, Willem J. Flameng, Yoshinobu Onuma, and Osama Soliman

Objectives This study aimed to validate a dedicated software for quantitative videodensitometric angiographic assessment of mitral regurgitation (QMR).

15 julio 2021

2-Year Outcomes for Transcatheter Repair in Patients With Mitral Regurgitation From the CLASP Study

Molly Szerlip, Konstantinos S. Spargias, Raj Makkar, Saibal Kar, Robert M. Kipperman, William W. O’Neill, Martin K.C. Ng, Robert L. Smith, Neil P. Fam, Michael J. Rinaldi, O. Christopher Raffel, Darren L. Walters, Justin Levisay, Matteo Montorfano, Azeem Latib, John D. Carroll, Georg Nickenig, Stephan Windecker, Leo Marcoff, Gideon N. Cohen, Ulrich Schäfer, John G. Webb, and D. Scott Lim

Objectives This study reports 2-year outcomes from the multicenter, prospective, single-arm CLASP study with functional mitral regurgitation (FMR) and degenerative MR (DMR) analysis.

15 julio 2021

Right Ventricular Contraction Patterns in Patients Undergoing Transcatheter Tricuspid Valve Repair for Severe Tricuspid Regurgitation

Karl-Patrik Kresoja, Karl-Philipp Rommel, Christian Lücke, Matthias Unterhuber, Christian Besler, Maximilian von Roeder, Anne Rebecca Schöber, Thilo Noack, Matthias Gutberlet, Holger Thiele, and Philipp Lurz

Objectives This study investigated patterns of right ventricular (RV) contraction by using cardiac magnetic resonance (CMR) imaging in patients undergoing transcatheter tricuspid valve repair (TTVR).

15 julio 2021

Postoperative Atrial Fibrillation or Flutter Following Transcatheter or Surgical Aortic Valve Replacement: PARTNER 3 Trial

Bahira Shahim, S. Chris Malaisrie, Isaac George, Vinod H. Thourani, Angelo B. Biviano, Mark Russo, David L. Brown, Vasilis Babaliaros, Robert A. Guyton, Susheel K. Kodali, Tamim M. Nazif, Samir Kapadia, Philippe Pibarot, James M. McCabe, Mathew Williams, Philippe Genereux, Michael Lu, Xiao Yu, Maria Alu, John G. Webb, Michael J. Mack, Martin B. Leon, and Ioanna Kosmidou

The aim of this study was to assess the incidence and prognostic impact of early and late postoperative atrial fibrillation or flutter (POAF) in patients with severe aortic stenosis (AS) treated with transcatheter aortic valve replacement (TAVR) or surgical aortic valve replacement (SAVR).

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