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ESTUDIOS


01 mayo 2017

JACC: CARDIOVASCULAR INTERVENTIONS. Impact of Institutional and Operator Volume on Short-Term Outcomes of Percutaneous Coronary Intervention: A Report From the Japanese Nationwide Registry

Taku Inohara, Shun Kohsaka, Kyohei Yamaji, Tetsuya Amano, Kenshi Fujii, Hirotaka Oda, Shiro Uemura, Kazushige Kadota, Hiroaki Miyata, Masato Nakamura, J-PCI Registry Investigators, Taku Inohara, Shun Kohsaka, Kyohei Yamaji, Tetsuya Amano, Kenshi Fujii, Hirotaka Oda, Shiro Uemura, Kazushige Kadota, Hiroaki Miyata, Masato Nakamura, Kazushige Kadota, Nobuo Shiode, Nobuhiro Tanaka, Tetsuya Amano, Shiro Uemura, Takashi Akasaka, Yoshihiro Morino, Kenshi Fujii, Hiroshi Hikichi, Tetsuya Amano, Kenshi Fujii, Shun Kohsaka, Hideki Ishii, Kengo Tanabe, Yukio Ozaki, Satoru Sumitsuji, Osamu Iida, Hidehiko Hara, Hiroaki Takashima, Shinichi Shirai, Mamoru Nansato, Taku Inohara, Yasunori Ueda, Yohei Numasawa and Shigetaka Noma

Objectives: The aim of this study was to assess the volume–outcome relationship for PCI within the nationwide registration system in Japan.

01 abril 2017

JACC: CARDIOVASCULAR INTERVENTIONS. Diagnostic Performance of Resting and Hyperemic Invasive Physiological Indices to Define Myocardial Ischemia

Doyeon Hwang, Ki-Hyun Jeon, Joo Myung Lee, Jonghanne Park, Chee Hae Kim, Yaliang Tong, Jinlong Zhang, Ji-In Bang, Minseok Suh, Jin Chul Paeng, Sang-Hoon Na, Gi Jeong Cheon, Christopher M. Cook, Justin E. Davies and Bon-Kwon Koo

Objectives: The authors sought to compare the diagnostic performance of fractional flow reserve (FFR), instantaneous wave-free ratio (iFR), and resting distal coronary artery pressure/aortic pressure (Pd/Pa) using 13N-ammonia positron emission tomography (PET).

01 abril 2017

JACC: CARDIOVASCULAR INTERVENTIONS. Economic Outcomes of Bioresorbable Vascular Scaffolds Versus Everolimus-Eluting Stents in Patients Undergoing Percutaneous Coronary Intervention

Suzanne J. Baron, Yang Lei, Khaja Chinnakondepalli, Katherine Vilain, Elizabeth A. Magnuson, Dean J. Kereiakes, Stephen G. Ellis, Gregg W. Stone, David J. Cohen and ABSORB III Investigators

Objectives: The purpose of this study was to evaluate the economic impact of the Absorb bioresorbable vascular scaffold compared with the Xience everolimus-eluting stent in patients undergoing percutaneous coronary intervention.

01 abril 2017

JACC: CARDIOVASCULAR INTERVENTIONS. Vasomotor Response to Nitroglycerine Over 5 Years Follow-Up After Everolimus-Eluting Bioresorbable Scaffold Implantation

Dariusz Dudek, Lukasz Rzeszutko, Yoshinobu Onuma, Yohei Sotomi, Rafal Depukat, Susan Veldhof, Divine Ediebah, Peter Staehr, Wojciech Zasada, Krzysztof P. Malinowski, Grzegorz L. Kaluza and Patrick W. Serruys

Objectives: This study investigated the vasomotor response to nitroglycerine (NTG) up to 5 years after ABSORB implantation.

01 abril 2017

JACC: CARDIOVASCULAR INTERVENTIONS. Intentional Percutaneous Laceration of the Anterior Mitral Leaflet to Prevent Outflow Obstruction During Transcatheter Mitral Valve Replacement

Vasilis C. Babaliaros, Adam B. Greenbaum, Jaffar M. Khan, Toby Rogers, Dee Dee Wang, Marvin H. Eng, William W. O’Neill, Gaetano Paone, Vinod H. Thourani, Stamatios Lerakis, Dennis W. Kim, Marcus Y. Chen and Robert J. Lederman

Objectives: This study sought to use a new catheter technique to split the anterior mitral valve leaflet (AML) and prevent iatrogenic left ventricular outflow tract (LVOT) obstruction immediately before transcatheter mitral valve replacement (TMVR).

01 abril 2017

JACC: CARDIOVASCULAR INTERVENTIONS. Computed Tomography–Based Oversizing Degrees and Incidence of Paravalvular Regurgitation of a New Generation Transcatheter Heart Valve

Philipp Blanke, Philippe Pibarot, Rebecca Hahn, Neil Weissman, Susheel Kodali, Vinod Thourani, Rupa Parvataneni, Danny Dvir, Christopher Naoum, Bjarne L. Nørgaard, Pamela Douglas, Wael Jaber, Omar K. Khalique, Hasan Jilaihawi, Michael Mack, Craig Smith, Martin Leon, John Webb and Jonathon Leipsic

Objectives: The aim of the study was to investigate the influence of the extent of computed tomography (CT)–based area and perimeter oversizing on the incidence and severity of paravalvular aortic regurgitation (PAR) for the Edwards SAPIEN 3 (Edwards Lifesciences, Irvine, California) device, using CT data and echocardiographic outcome data of the PARTNER II (Placement of AoRTic TraNscathetER Valves Trial II) SAPIEN 3 intermediate-risk cohort.

01 mayo 2017

CATHETERIZATION & CARDIOVASCULAR INTERVENTIONS. Cost-effectiveness of percutaneous coronary intervention with cobalt-chromium everolimus eluting stents versus bare metal stents: Results from a patient level meta-analysis of randomized trials

Nicole Ferko MSC, Giuseppe Ferrante MD, PhD, James T. Hasegawa MPH, MBA, Tanya Schikorr MSC, Ireena M. Soleas MSC, John B. Hernandez PhD, Manel Sabaté MD, PhD, Christoph Kaiser MD, Salvatore Brugaletta MD, PhD, Jose Maria de la Torre Hernandez MD, PhD, Soeren Galatius MD, DMSC, Angel Cequier MD, PhD, Franz Eberli MD, Adam de Belder MD, FRCP, Patrick W. Serruys MD, PhD, Marco Valgimigli MD, PhD

Background: Second-generation drug eluting stents (DES) may reduce costs and improve clinical outcomes compared to first-generation DES with improved cost-effectiveness when compared to bare metal stents (BMS). We aimed to conduct an economic evaluation of a cobalt-chromium everolimus eluting stent (Co-Cr EES) compared with BMS in percutaneous coronary intervention (PCI).

15 febrero 2017

CATHETERIZATION & CARDIOVASCULAR INTERVENTIONS. New technique for treatment of postcatheterization radial artery pseudoaneurysm

Avtandil M. Babunashvili MD, PhD, Samir B. Pancholy MD, FSCAI, Dmitriy S. Kartashov MD

We report a new technique for treatment of radial artery pseudoaneurysm (RAP) caused by transradial access (TRA) for coronary angiography. Traditional extrinsic compression with radial flow cessation leads to a local milieu likely associated with an increase in probability of radial artery occlusion (RAO). Our technique involves obtaining ipsilateral radial artery access distal to the neck of the RAP followed by a prolonged sheath dwell time covering the neck of the RAP which allows the RAP sac to thrombose and maintains radial artery lumen patency.

01 febrero 2017

AMERICAN HEART JOURNAL. Inadequacy of existing clinical prediction models for predicting mortality after transcatheter aortic valve implantation

Glen P. Martin MS, Matthew Sperrin PhD, Peter F. Ludman MA, MD, FRCP, FESC, Mark A. de Belder MA, MD, FRCP, Chris P. Gale PhD, FRCP, FESC, William D.Toff MD, FRCP, FESC, Neil E. Moat MBBS, MS

Background: The performance of emerging transcatheter aortic valve implantation (TAVI) clinical prediction models (CPMs) in national TAVI cohorts distinct from those where they have been derived is unknown. This study aimed to investigate the performance of the German Aortic Valve, FRANCE-2, OBSERVANT and American College of Cardiology (ACC) TAVI CPMs compared with the performance of historic cardiac CPMs such as the EuroSCORE and STS-PROM, in a large national TAVI registry.

01 febrero 2017

AMERICAN HEART JOURNAL. An age- and sex-specific gene expression score is associated with revascularization and coronary artery disease: Insights from the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) trial

Deepak Voora MD, Adrian Coles PhD, Kerry L. Lee PhD, Udo Hoffmann MD, MPH, James A. Wingrove PhD, Brian Rhees PhD, Lin Huang PhD, Susan E. Daniels PhD

Background: Identifying predictors of coronary artery disease (CAD)-related procedures and events remains a priority.

01 febrero 2017

AMERICAN HEART JOURNAL. Trial design: Rivaroxaban for the prevention of major cardiovascular events after transcatheter aortic valve replacement: Rationale and design of the GALILEO study

Stephan Windecker, MD, Jan Tijssen, PhD, Gennaro Giustino, MD, Ana H. C. Guimarães, PhD, Roxana Mehran, MD, Marco Valgimigli, MD, PhD, Pascal Vranckx, MD, PhD, Robert C. Welsh, MD, Usman Baber, MD

Background: Optimal antithrombotic treatment after transcatheter aortic valve replacement (TAVR) is unknown and determined empirically. The direct factor Xa inhibitor rivaroxaban may potentially reduce TAVR-related thrombotic complications and premature valve failure.

01 marzo 2017

AMERICAN HEART JOURNAL. Anemia is associated with bleeding and mortality, but not stroke, in patients with atrial fibrillation: Insights from the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) trial

B. Daan Westenbrink, MD, PhD, Marco Alings, MD, PhD, Christopher B. Granger, MD, John H. Alexander, MD, Renato D. Lopes, MD, PhD, Elaine M. Hylek, MD, MPH, Laine Thomas, PhD, Daniel M. Wojdyla, MS, Michael Hanna, MD, Matyas Keltai, MD, PhD, DSc, P. Gabriel Steg, MD, Raffaele De Caterina, MD, PhD, Lars Wallentin, MD and Wiek H. van Gilst, PhD

Background: Patients with atrial fibrillation (AF) are prone to cardiovascular events and anticoagulation-related bleeding complications. We hypothesized that patients with anemia are at increased risk for these outcomes.

01 marzo 2017

AMERICAN HEART JOURNAL. Cardioversion and subsequent quality of life and natural history of atrial fibrillation.

Sean D. Pokorney, MD, MBA, Sunghee Kim, PhD, Laine Thomas, PhD, Gregg C. Fonarow, MD, Peter R. Kowey, MD, Bernard J. Gersh, MB, ChB, DPhil, Kenneth W. Mahaffey, MD, Eric D. Peterson, MD, MPH and Jonathan P. Piccini, MD, MHS

Background: Cardioversion is a class I procedure for patients with symptomatic atrial fibrillation (AF) pursuing rhythm control. There are few contemporary reports on quality of life and outcomes after cardioversion.

01 abril 2017

AMERICAN HEART JOURNAL. Design and rationale of the COMPARE-ACUTE trial: Fractional flow reserve–guided primary multivessel percutaneous coronary intervention to improve guideline indexed actual standard of care for treatment of ST-elevation myocardial infarction in patients with multivessel coronary disease

Pieter C. Smits, MD, PhD, Amira Assaf, MD, Gert Richardt, MD, PhD, Elmir Omerovic, MD, Mohamed Abdel-Wahab, MD and Franz-Joseph Neumann, MD

Aims: What the best strategy is for nonculprit lesions in ST-elevation myocardial infarction (STEMI) patients presenting with multivessel disease remains a clinical dilemma. Based on recent clinical studies suggesting that complete revascularization in the acute phase is beneficial, the European Society of Cardiology and American College of Cardiology/American Heart Association guidelines have been recently changed from class 3 discouragement to a class 2B recommendation concerning the treatment of the nonculprit lesions in the acute index procedure. However, in these recent studies, nonculprit lesion treatment was guided by angiography, which is known for its poor accuracy in determining ischemia. Fractional flow reserve (FFR) guidance for treatment of nonculprit vessels seems to be a reasonable approach, and in the acute setting of STEMI, it is not yet investigated. The COMPARE-ACUTE trial aims to investigate FFR-guided complete revascularization in comparison to a culprit lesion treatment–only strategy in STEMI patients with multivessel disease presenting for primary percutaneous coronary intervention.

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