Objectives: The aim of this study was to analyze the risk factors and mid-term outcomes associated with post-procedure heart blocks (PPHBs) after transcatheter closure of perimembranous ventricular septal defect (pmVSD).
Journal of the American College of The aim of this multicenter study was to evaluate the safety of discontinuing oral anticoagulation therapy (OAT) after apparently successful pulmonary vein isolation. Cardiology Vol. 55, No. 8, 2010. Copyright © 2010 by the American College of Cardiology Foundation ISSN: 0735-1097/10. Published by Elsevier Inc.
Objectives: This study was designed to assess the prevalence of provoked exercise desaturation (PED) in patients with patent foramen ovale (PFO) referred for cardiovascular evaluation and to evaluate the impact of PFO closure.
The concluding statement from a first-in-man case report published in Circulation in 2002 was: ‘‘Nonsurgical implantation of a prosthetic heart valve can be successfully achieved with immediate and midterm hemodynamic and clinical improvement’’ [1]. The lead author of this short manuscript was Alain Cribier, and the procedure involved transcatheter placement of a bioprosthetic aortic valve in a desperately ill man with critical aortic stenosis (AS) and no therapy alternatives. At the time, it was impossible to predict the future of this new medical therapy, which at the same time appeared both reckless and revolutionary. In retrospect, 10 years later, this humble concluding statement laid the foundation for a medical breakthrough that has altered the landscape of cardiovascular medicine. The odyssey and the anniversary of transcatheter aortic valve replacement (TAVR) deserve our attention and careful reflection. Archives of Cardiovascular Disease (2012) 105, 129—131. Copyright © 2012 Published by Elsevier Masson SAS.
Aortic valve replacement (AVR) is a routine procedure for decades to treat patients with symptomatic aortic stenosis. The introduction of transcatheter aortic valve implantation (TAVI) by Professor Alain Cribier has paved the way for minimally invasive therapeutic options for elderly and high-risk patients with aortic stenosis. Transfemoral and transapical aortic valve implantations have become routine procedures in many centres around Europe. TAVI is usually being performed together by experienced cardiologists and cardiac surgeons who build the interdisciplinary ‘Heart Team’. In the future, improved devices together with advanced fusion imaging will lead to a further improvement in clinical outcomes for the sake of our patients. Archives of Cardiovascular Disease (2012) 105, 174—180 Copyright © 2012 Published by Elsevier Masson SAS.
La fibrilación auricular está asociada a accidentes vasculares de origen embólico que frecuentemente resultan en muerte o invalidez. Siendo eficaz en la reducción de esos eventos, la anticoagulación posee varias limitaciones y viene siendo ampliamente subutilizada. Más de 90% de los trombos identificados en los portadores de fibrilación auricular sin enfermedad valvular se originan en la orejuela auricular izquierda, cuya oclusión es investigada como una alternativa a la anticoagulación. Arq Bras Cardiol 2012;98(2):143-150.
Atrial fibrillation (AF) is one of the major risk factors for ischemic stroke, and 90% of thromboembolisms in these patients arise from the left atrial appendage (LAA). Recently, it has been documented that an LAA occlusion device (OD) is not inferior to warfarin therapy, and that it reduces mortality and risk of stroke in patients with AF. Yonsei Med J 53(1):83-90, 2012. © Copyright: Yonsei University College of Medicine 2012
Context High platelet reactivity while receiving clopidogrel has been linked to cardiovascular events after percutaneous coronary intervention (PCI), but a treatment strategy for this issue is not well defined. Objective To evaluate the effect of high-dose compared with standard-dose clopidogrel in patients with high on-treatment platelet reactivity after PCI. Copyright © 2011 American Medical Association. All rights reserved. JAMA, March 16, 2011—Vol 305, No. 11
Very late stent thrombosis (VLST) was reported to occur even in patients with bare metal stent (BMS) implantation, although the annual incidence of VLST after BMS was much lower than that after drug-eluting stent implantation. Pathophysiologic mechanisms of VLST after BMS implantation remain largely unknown. Copyright © 2012 American Heart Association. All rights reserved. Print ISSN: 1941-7640. Online ISSN:1941-7632
Objectives: This study sought to compare increasing doses of intracoronary (IC) adenosine or IC sodium nitroprusside versus intravenous (IV) adenosine for fractional flow reserve (FFR) assessment.
Aims: To compare primary percutaneous coronary intervention (pPCI) and fibrinolysis in very old patients with ST-segment elevation myocardial infarction (STEMI), in whom head-to-head comparisons between both strategies are scarce. Published on behalf of the European Society of Cardiology. European Heart Journal (2011) 32, 51–60. All rights reserved. Copyright The Author 2010.
This study sought to: 1) determine the incidence, degree, and timing of the rise in serum cardiac markers of myocardial injury associated with uncomplicated transcatheter aortic valve implantation (TAVI); and 2) evaluate the predictive factors and prognostic value of myocardial injury associated with TAVI. Journal of the American College of Cardiology. Vol. 57, No. 20, 2011. Copyright © 2011 by the American College of Cardiology Foundation. Published by Elsevier Inc. ISSN 0735-1097.
The aim of this study was to evaluate the incidence, predictors, and long-term outcomes of patients with in-stent restenosis (ISR) after percutaneous coronary intervention (PCI) with drug-eluting stents (DES) for unprotected left main coronary artery (LMCA) disease. Journal of the American College of Cardiology. Vol. 57, No. 12, 2011. Copyright © 2011 by the American College of Cardiology Foundation. Published by Elsevier Inc. ISSN 0735-1097
The objective of this study was to evaluate the acute hemodynamic consequences of mitral valve (MV) repair with the MitraClip device (Abbott Vascular, Menlo Park, California). Journal of the American College of Cardiology. Vol. 57, No. 16, 2011. Copyright © 2011 by the American College of Cardiology Foundation. Published by Elsevier Inc. ISSN 0735-1097.
The purpose of this study was to evaluate the safety, device performance, and clinical outcome up to 2 years for patients undergoing transcatheter aortic valve implantation (TAVI). Journal of the American College of Cardiology. Vol. 57, No. 16, 2011. Copyright © 2011 by the American College of Cardiology Foundation. Published by Elsevier Inc. ISSN 0735-1097
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