01 junio 2013

CIRCULATION. Bayesian Methods Affirm the Use of Percutaneous Coronary Intervention to Improve Survival in Patients With Unprotected Left Main Coronary Artery Disease

John A. Bittl, MD; Yulei He, PhD; Alice K. Jacobs, MD; Clyde W. Yancy, MD; Sharon-Lise T. Normand, PhD; on behalf of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines

Background—Several randomized clinical trials support the use of coronary artery bypass grafting (CABG) for patients with unprotected left main coronary artery disease. Studies suggesting the equivalence of percutaneous coronary intervention (PCI) with CABG for this indication indirectly support the 2011 American College of Cardiology Foundation/American Heart Association Class IIa recommendation for PCI to improve survival in patients with unprotected left main coronary artery disease. We tested whether bayesian approaches uphold the new recommendation.

01 junio 2012

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Outcomes After Unrestricted Use of Everolimus-Eluting and Sirolimus-Eluting Stents in Routine Clinical Practice. A Multicenter, Prospective Cohort Study

Duk-Woo Park, MD, Young-Hak Kim, MD, Hae-Geun Song, MD, Jung-Min Ahn, MD, Won-Jang Kim, MD, Jong-Young Lee, MD, Soo-Jin Kang, MD, Seung-Whan Lee, MD, Cheol Whan Lee, MD, Seong-Wook Park, MD, Sung-Cheol Yun, PhD, Sung Ho Her, MD, Seung Ho Hur, MD, Jin Sik Park, MD, Myeong-Kon Kim, MD, Yun Seok Choi, MD, Hyun Sook Kim, MD, Jang-Hyun Cho, MD, Sang Gon Lee, MD, Yong Whi Park, MD, Myung-Ho Jeong, MD, Bong Ki Lee, MD, Nae-Hee Lee, MD, Do-Sun Lim, MD, Junghan Yoon, MD, Ki Bae Seung, MD, Won-Yong Shin, MD, Seung-Woon Rha, MD, Kee-Sik Kim, MD, Seung-Jea Tahk, MD, Byoung Eun Park, MD, Taehoon Ahn, MD, Joo-Young Yang, MD, Yong Seok Jeong, MD, Jay-Hyun Rhew, MD and Seung-Jung Park, MD for the IRIS-DES Investigators

Background—It remains unclear whether there are differences in the safety and efficacy outcomes between everolimus-eluting stents (EES) and sirolimus-eluting stents (SES) in contemporary practice.

01 junio 2013

CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS. Differential long-term outcomes of zotarolimus-eluting stents compared with sirolimus-eluting and paclitaxel-eluting stents in diabetic and nondiabetic patients: Two-year subgroup analysis of the ZEST randomized trial

Sun-Joo Jang MD, Duk-Woo Park MD, Won-Jang Kim MD, Young-Hak Kim MD, Sung-Cheol Yun PhD, Soo-Jin Kang MD, Seung-Whan Lee MD, Cheol Whan Lee MD, Seong-Wook Park MD, Seung-Jung Park MD

Objectives: To evaluate the differential treatment effects of zotarolimus-eluting stents (ZES), sirolimus-eluting stents (SES), and paclitaxel-eluting stents (PES) according to diabetic status.

01 junio 2013

JACC. The Transaortic Approach for Transcatheter Aortic Valve Replacement. Initial Clinical Experience in the United States

Objectives: This study sought to investigate the technical feasibility and safety of the transaortic (TAO) transcatheter aortic valve replacement (TAVR) approach in patients not eligible for transfemoral (TF) access by using a device commercially available in the United States.

01 junio 2012

EUROPEAN HEART JOURNAL. Endothelial-dependent vasomotion in a coronary segment treated by ABSORB everolimus-eluting bioresorbable vascular scaffold system is related to plaque composition at the time of bioresorption of the polymer: indirect finding of vascular reparative therapy?

Salvatore Brugaletta, Jung Ho Heo, Hector M. Garcia-Garcia, Vasim Farooq, Robert Jan van Geuns, Bernard de Bruyne, Dariusz Dudek, Pieter C. Smits, Jacques Koolen, Dougal McClean, Cecile Dorange, Susan Veldhof, Richard Rapoza, Yoshinobu Onuma, Nico Bruining, John A. Ormiston and Patrick W. Serruys

Aims: To analyse the vasoreactivity of a coronary segment, previously scaffolded by the ABSORB bioresorbable vascular scaffold (BVS) device, in relationship to its intravascular ultrasound–virtual histology (IVUS–VH) composition and reduction in greyscale echogenicity of the struts. Coronary segments, transiently scaffolded by a polymeric device, may in the long-term recover a normal vasomotor tone. Recovery of a normal endothelial-dependent vasomotion may be enabled by scaffold bioresorption, composition of the underlying tissue, or a combination of both mechanisms.

01 junio 2012

JACC. Quantification and Impact of Untreated Coronary Artery Disease After Percutaneous Coronary Intervention. The Residual SYNTAX (Synergy Between PCI With Taxus and Cardiac Surgery) Score

Philippe Généreux, MD; Tullio Palmerini, MD; Adriano Caixeta, MD, PhD; Gregg Rosner, MD; Philip Green, MD; Ovidiu Dressler, MD; Ke Xu, PhD; Helen Parise, PhD; Roxana Mehran, MD; Patrick W. Serruys; Gregg W. Stone, MD

Objectives: The purpose of this study was to quantify the extent and complexity of residual coronary stenoses following percutaneous coronary intervention (PCI) and to evaluate its impact on adverse ischemic outcomes.

01 junio 2012

JACC: CARDIOVASCULAR INTERVENTIONS. Computed Tomographic Angiography–Verified Plaque Characteristics and Slow-Flow Phenomenon During Percutaneous Coronary Intervention

Takahide Kodama, MD, PhD; Takeshi Kondo, MD, PhD; Akitsugu Oida, MD, PhD; Shinichiro Fujimoto, MD, PhD; Jagat Narula, MD, PhD

Objectives: This study sought to identify whether computed tomographic angiographic (CTA) plaque characteristics are associated with slow-flow phenomenon (SF) during percutaneous coronary intervention (PCI).

01 junio 2013

JACC. Prevalence and Prognostic Role of Resistant Hypertension in Chronic Kidney Disease Patients

Luca De Nicola, MD, PhD; Francis B. Gabbai, MD; Rajiv Agarwal, MD; Paolo Chiodini, MSc; Silvio Borrelli, MD; Vincenzo Bellizzi, MD, PhD; Felice Nappi, MD; Giuseppe Conte, MD; Roberto Minutolo, MD, PhD

Objectives: This study sought to evaluate in chronic kidney disease (CKD) prevalence and prognosis of true resistant hypertension (RH) (i.e., confirmed by ambulatory blood pressure [ABP] monitoring).

01 mayo 2013

CIRCULATION. Intracoronary Injection of Bone Marrow–Derived Mononuclear Cells Early or Late After Acute Myocardial Infarction

Daniel Sürder, MD; Robert Manka, MD; Viviana Lo Cicero, PhD; Tiziano Moccetti, MD; Kaspar Rufibach, PhD; Sabrina Soncin, PhD; Lucia Turchetto, PhD; Marina Radrizzani, PhD; Giuseppe Astori, PhD; Juerg Schwitter, MD; Paul Erne, MD; Michel Zuber, MD; Christoph Auf der Maur, MD; Peiman Jamshidi, MD; Oliver Gaemperli, MD; Stephan Windecker, MD; Aris Moschovitis, MD; Andreas Wahl, MD; Ines Bühler; Christophe Wyss, MD; Sebastian Kozerke, PhD; Ulf Landmesser, MD; Thomas F. Lüscher, MD; Roberto Corti, MD

Background—Intracoronary administration of autologous bone marrow–derived mononuclear cells (BM-MNC) may improve remodeling of the left ventricle (LV) after acute myocardial infarction. The optimal time point of administration of BM-MNC is still uncertain and has rarely been addressed prospectively in randomized clinical trials.

01 junio 2012

CIRCULATION. Short- and Long-Term Outcomes With Drug-Eluting and Bare-Metal Coronary Stents. A Mixed-Treatment Comparison Analysis of 117 762 Patient-Years of Follow-Up From Randomized Trials

Sripal Bangalore, MD, MHA; Sunil Kumar, MD; Mario Fusaro, MD; Nicholas Amoroso, MD; Michael J. Attubato, MD; Frederick Feit, MD; Deepak L. Bhatt, MD, MPH; James Slater, MD

Background—Drug-eluting stents (DES) have been in clinical use for nearly a decade; however, the relative short- and long-term efficacy and safety of DES compared with bare-metal stents (BMS) and among the DES types are less well defined.

01 junio 2012

EUROPEAN HEART JOURNAL. Impact of incomplete stent apposition on long-term clinical outcome after drug-eluting stent implantation

Stéphane Cook, Parham Eshtehardi, Bindu Kalesan, Lorenz Räber, Peter Wenaweser, Mario Togni, Aris Moschovitis, Rolf Vogel, Christian Seiler, Franz R. Eberli, Thomas Lüscher, Bernhard Meier, Peter Jüni and Stephan Windecker

Aims: Late acquired incomplete stent apposition (ISA) is more common after drug-eluting stent (DES) than bare metal stent (BMS) implantation and has been associated with vascular hypersensitivity and stent thrombosis (ST). We investigated the impact of incidentally discovered ISA as assessed by intravascular ultrasound (IVUS) 8 months after DES implantation on the long-term clinical outcome.

01 junio 2013

THE AMERICAN JOURNAL OF CARDIOLOGY. Risk of stroke with percutaneous coronary intervention compared with on-pump and off-pump coronary artery bypass graft surgery: Evidence from a comprehensive network meta-analysis

Tullio Palmerini, MD , Giuseppe Biondi-Zoccai, MD , Diego Della Riva, MD , Andrea Mariani, MD , Carlo Savini, MD , Marco Di Eusanio, MD , Philippe Genereux, MD , Giacomo Frati, MD , Antonino G.M. Marullo, MD, PhD , Giovanni Landoni, MD , Teresa Greco, MSc , Angelo Branzi, MD , Stefano De Servi, MD , Germano Di Credico, MD , Nevio Taglieri, MD , Mathew R. Williams, MD , Gregg W. Stone, MD

Background: Although some trials have reported that on-pump coronary artery bypass graft (CABG) surgery may be associated with higher rates of stroke than percutaneous coronary intervention (PCI), whether stroke is more common after off-pump CABG compared with PCI is unknown. We therefore sought to determine whether off-pump CABG is associated with an increased risk of stroke compared with PCI by means of network meta-analysis.

01 junio 2013

JACC. A Novel Tool for Reliable and Accurate Prediction of Renal Complications in Patients Undergoing Percutaneous Coronary Intervention

Hitinder S. Gurm, MD; Milan Seth, MS; Judith Kooiman, MSc; David Share, MD

Objectives: The aim of the study was to develop and validate a tool for predicting risk of contrast-induced nephropathy (CIN) in patients undergoing contemporary percutaneous coronary intervention (PCI).

01 junio 2012

JACC: CARDIOVASCULAR INTERVENTIONS. Vascular Response of the Segments Adjacent to the Proximal and Distal Edges of the ABSORB Everolimus-Eluting Bioresorbable Vascular Scaffold: 6-Month and 1-Year Follow-Up Assessment. A Virtual Histology Intravascular Ultrasound Study From the First-in-Man ABSORB Cohort B Trial

Bill D. Gogas, MD; Patrick W. Serruys, MD, PhD; Roberto Diletti, MD; Vasim Farooq, MBChB; Salvatore Brugaletta, MD; Maria D. Radu, MD; Jung Ho Heo, MD; Yoshinobu Onuma, MD; Robert-Jan M. van Geuns, MD, PhD; Evelyn Regar, MD, PhD; Bernard De Bruyne, MD, PhD; Bernard Chevalier, MD; Leif Thuesen, MD; Pieter C. Smits, MD, PhD; Dariusz Dudek, MD; Jacques Koolen, MD, PhD; Stefan Windecker, MD; Robert Whitbourn, MD; Karine Miquel-Hebert, PhD; Cecile Dorange, MSc; Richard Rapoza, PhD; Hector M. Garcia-Garcia, MD, MSc, PhD; Dougal McClean, MD; John A. Ormiston, MBChB, PhD

Objectives: This study sought to investigate in vivo the vascular response at the proximal and distal edges of the second-generation ABSORB everolimus-eluting bioresorbable vascular scaffold (BVS).

01 junio 2012

RADIOLOGY. Cardioembolic Stroke: Dual-Energy Cardiac CT for Differentiation of Left Atrial Appendage Thrombus and Circulatory Stasis

Jin Hur, MD, PhD, Young Jin Kim, MD, PhD, Hye-Jeong Lee, MD, PhD, Ji Eun Nam, MD, Yoo Jin Hong, MD, Hee Yeong Kim, MD, Ji Won Lee, MD and Byoung Wook Choi, MD, PhD

Purpose: To assess the diagnostic performance of dual-energy cardiac computed tomography (CT) in the detection of left atrial appendage (LAA) thrombi and differentiation between thrombus and circulatory stasis in patients with stroke, by using transesophageal echocardiography (TEE) as the reference standard.