01 agosto 2013

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Impact of Coronary Microvascular Function on Long-term Cardiac Mortality in Patients With Acute ST-Segment–Elevation Myocardial Infarction

Tim P. van de Hoef, MD*, Matthijs Bax, MD*, Martijn Meuwissen, MD, PhD, Peter Damman, MD, Ronak Delewi, MD, Robbert J. de Winter, MD, PhD, Karel T. Koch, MD, PhD, Carl Schotborgh, MD, PhD, José P.S. Henriques, MD, PhD, Jan G.P. Tijssen, PhD and Jan J. Piek, MD, PhD

Background—Microvascular function is increasingly being recognized as an important marker of risk in coronary artery disease, and may be accurately assessed by intracoronary Doppler flow velocity measurements. In the setting of ST-segment–elevation myocardial infarction there are limited data regarding the prognostic value of microvascular function in both infarct-related and reference coronary arteries for long-term clinical outcome. We sought to determine the prognostic value of microvascular function, as assessed by Doppler flow velocity measurements, for cardiac mortality after primary percutaneous coronary intervention for acute ST-segment–elevation myocardial infarction.

CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS.

Ankur Sethi MD*, Anurag Bajaj MD, Amol Bahekar MD, MPH, Rohit Bhuriya MD, Mukesh Singh MD, Aziz Ahmed MD, FACC, Sandeep Khosla MD, FACC

Background: Recent studies have casted a doubt on usefulness of routine glycoprotein IIb/IIIA inhibitors (GPI) in patients, pretreated with aspirin and clopidogrel, undergoing primary percutaneous coronary intervention (PCI) for ST elevation myocardial infarction (STEMI).

01 agosto 2013

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Transcatheter Aortic Valve Implantation for Patients With Severe Bicuspid Aortic Valve Stenosis

Kentaro Hayashida, MD, PhD, FESC, Erik Bouvier, MD, Thierry Lefèvre, MD, FSCAI, FESC, Bernard Chevalier, MD, FSCAI, FESC, Thomas Hovasse, MD, Mauro Romano, MD, Philippe Garot, MD, FESC, Yusuke Watanabe, MD, Arnaud Farge, MD, Patrick Donzeau-Gouge, MD, Bertrand Cormier, MD and Marie-Claude Morice, MD, FESC

Background—Bicuspid aortic valve (BAV) is regarded as a relative contraindication to transcatheter aortic valve implantation attributable to the risk of uneven expansion of the bioprosthesis. The purpose of this study was to evaluate the efficacy and safety of transcatheter aortic valve implantation in patients with BAV.

CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS. Is euroscore II better than EuroSCORE in predicting mortality after transcatheter aortic valve implantation?

Yusuke Watanabe MD, Kentaro Hayashida MD, PhD, Thierry Lefèvre MD, FSCAI, FESC*, Bernard Chevalier MD, FSCAI, FESC, Thomas Hovasse MD, Mauro Romano MD, Philippe Garot MD, FESC, Arnaud Farge MD, Patrick Donzeau-Gouge MD, Erik Bouvier MD, Bertrand Cormier MD, Marie-Claude Morice MD, FESC, FACC

Objectives: The purpose of this study was to examine the performance of the European system for cardiac operative risk evaluation II (ESII) in patients undergoing transcatheter aortic valve implantation (TAVI).

01 agosto 2013

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Prosthesis Oversizing in Balloon-Expandable Transcatheter Aortic Valve Implantation Is Associated With Contained Rupture of the Aortic Root

Philipp Blanke, MD, Jochen Reinöhl, MD, Christian Schlensak, MD, Matthias Siepe, MD, Gregor Pache, MD, Wulf Euringer, MD, Annette Geibel-Zehender, MD, Christopher Bode, MD, Mathias Langer, MD, Friedhelm Beyersdorf, MD and Manfred Zehender, MD

Background—To retrospectively investigate the potential cause of contained rupture of the aortic root in balloon-expandable transcatheter aortic valve implantation (TAVI) by means of pre- and postinterventional multislice computed tomography.

01 agosto 2012

RADIOLOGY. Quantification of Coronary Artery Calcium on the Basis of Dual-Energy Coronary CT Angiography

Florian Schwarz, MD, John W. Nance, Jr, MD, Balazs Ruzsics, MD, PhD, Gorka Bastarrika, MD, PhD, Alexander Sterzik, MD and U. Joseph Schoepf, MD

Purpose: To evaluate the feasibility of using virtual noncontrast material–enhanced (VNC) computed tomographic (CT) series derived from dual-energy CT imaging studies for coronary artery calcium quantification.

01 agosto 2013

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Paclitaxel-Coated Versus Uncoated Balloon Angioplasty Reduces Target Lesion Revascularization in Patients With Femoropopliteal Arterial Disease

Diego Porras, MD, Doff B. McElhinney, MD, Pedro del Nido, MD, James E. Lock, MD, Jeffrey Meadows, MD and Audrey C. Marshall, MD

Background—Stenting of the systemic ventricular outflow tract and creation or enlargement of a ventricular septal defect using stents are potential therapeutic options in rare patients with congenital heart disease who develop significant ventricular hypertension due to outflow obstruction. These stents may be at increased risk of fracture because of exposure to cyclic compressive stresses. The objective of this study was to evaluate the safety and efficacy of this intervention and to determine the incidence of stent fracture and other adverse outcomes after placement of intraventricular or interventricular stents for this indication.

01 julio 2012

CIRCULATION. Development of a Clinical Prediction Rule for Risk Stratification of Recurrent Venous Thromboembolism in Patients With Cancer-Associated Venous Thromboembolism

Martha L. Louzada, MD, MSc; Marc Carrier, MD, MSc; Alejandro Lazo-Langner, MD, MSc; Vi Dao, MD; Michael J. Kovacs, MD; Timothy O. Ramsay, PhD; Marc A. Rodger, MD, MSc; Jerry Zhang, BSc; Agnes Y.Y. Lee, MD, MSc; Guy Meyer, MD; Philip S. Wells, MD, MSc

Background—Long-term low-molecular-weight heparin (LMWH) is the current standard for treatment of venous thromboembolism (VTE) in cancer patients. Whether treatment strategies should vary according to individual risk of VTE recurrence remains unknown. We performed a retrospective cohort study and a validation study in patients with cancer-associated VTE to derive a clinical prediction rule that stratifies VTE recurrence risk.

01 julio 2012

CIRCULATION. Periprocedural Bleeding and Thromboembolic Events With Dabigatran Compared With Warfarin. Results From the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) Randomized Trial

Jeff S. Healey, MD, MSc; John Eikelboom, MD; James Douketis, MD; Lars Wallentin, MD, PhD; Jonas Oldgren, MD, PhD; Sean Yang, MSc; Ellison Themeles, BA; Hein Heidbuchel, MD; Alvaro Avezum, MD; Paul Reilly, PhD; Stuart J. Connolly, MD; Salim Yusuf, MD, DPhil; Michael Ezekowitz, MB, ChB, DPhil on behalf of the RE-LY Investigators

Background—Dabigatran reduces ischemic stroke in comparison with warfarin; however, given the lack of antidote, there is concern that it might increase bleeding when surgery or invasive procedures are required.

01 julio 2013

DIAGNOSTIC AND INTERVENTIONAL RADIOLOGY. Assessment of the coronary venous system by using cardiac CT

Berhan Genç, Aynur Solak, Neslin Şahin, Serkan Gür, Sena Kalaycıoğlu, Volkan Öztürk

PURPOSE: We aimed to investigate the coronary venous system and its variations by using dual source computed tomography (CT).

01 junio 2012

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Rupture of the Device Landing Zone During Transcatheter Aortic Valve Implantation. A Life-Threatening But Treatable Complication

Background—Iatrogenic damage of different structures of the aortic root, in the region of the so-called “device landing zone,” may occur during transcatheter aortic valve implantation (TAVI). It is mostly considered difficult to treat or even untreatable.

01 junio 2013

EUROPEAN HEART JOURNAL. Long-term clinical follow-up of the multicentre, randomized study to test immunosuppressive therapy with oral prednisone for the prevention of restenosis after percutaneous coronary interventions: Cortisone plus BMS or DES veRsus BMS alone to EliminAte Restenosis (CEREA-DES)

Flavio Ribichini, Fabrizio Tomai, Gabriele Pesarini, Carlo Zivelonghi, Andrea Rognoni, Giuseppe De Luca, Giacomo Boccuzzi, Patrizia Presbitero, Valeria Ferrero, Anna S. Ghini, Paolo Marino, Corrado Vassanelli, the CEREA-DES Investigators

Aims: To analyse the clinical outcome at 4 years in patients with coronary artery disease treated with bare metal stents (BMS) vs. BMS and oral prednisone, or drug-eluting stents (DES), all assuming similar adjunctive medical treatment.

01 mayo 2013

ORIGINAL. Infarto Agudo de Miocardio Con y Sin Elevación del ST, ¿Tienen definitivamente un pronóstico distinto?

Dr. Consuegra

El pronóstico del Infarto Agudo de Miocardio (IAM) con y sin elevación del segmento ST (IAMEST, IAMSEST, respectivamente) ha sido objeto de controversia en diferentes estudios1,2. Respecto de la mortalidad hospitalaria, un registro relevante, de origen francés relativamente reciente y colaborativo de 56 centros (OPERA)1, no apreció diferencias en mortalidad por cualquier causa (IAMEST vs. IAMSEST, 4.6 vs. 4.3 %, respectivamente).

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01 mayo 2013

ORIGINAL. Nuevos antiagregantes en la práctica actual. Revisión de evidencias

Dr. Consuegra

La antiagregación es principal en la prevención y el tratamiento del Síndrome Coronario Agudo (SCA). La aparición de nuevos antiagregantes ha supuesto la posibilidad para el médico de elegir entre diferentes fármacos que presentan distintas características. El presente documento revisa el conocimiento existente hasta el momento actual referente a los nuevos antiagregantes en el SCA.

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01 junio 2013

JACC. Comparison of Transcatheter and Surgical Aortic Valve Replacement in Severe Aortic Stenosis. A Longitudinal Study of Echocardiography Parameters in Cohort A of the PARTNER Trial (Placement of Aortic Transcatheter Valves)

Rebecca T. Hahn, MD; Philippe Pibarot, DVM, PhD; William J. Stewart, MD; Neil J. Weissman, MD; Deepika Gopalakrishnan, MD; Martin G. Keane, MD; Saif Anwaruddin, MD; Zuyue Wang, MD; Martin Bilsker, MD; Brian R. Lindman, MD; Howard C. Herrmann, MD; Susheel K. Kodali, MD; Raj Makkar, MD; Vinod H. Thourani, MD; Lars G. Svensson, MD; Jodi J. Akin, MS; William N. Anderson, PhD; Martin B. Leon, MD; Pamela S. Douglas, MD

Objectives: This study sought to compare echocardiographic findings in patients with critical aortic stenosis following surgical aortic valve replacement (SAVR) or transcatheter aortic valve replacement (TAVR).