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ESTUDIOS


21 mayo 2013

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Coronary Interventions. Remote Ischemic Preconditioning Improves Outcome at 6 Years After Elective Percutaneous Coronary Intervention. The CRISP Stent Trial Long-term Follow-up

William R. Davies, PhD, MRCP, Adam J. Brown, MRCP, William Watson, MRCP, Liam M. McCormick, MRCP, Nick E.J. West, MD, FRCP, David P. Dutka, MD, FRCP and Stephen P. Hoole, MA, DM, MRCP

Background: Postprocedural myocardial infarction (type 4a) has been shown to be an adverse prognostic indicator after elective percutaneous coronary intervention (PCI). The Cardiac Remote Ischemic Preconditioning in Coronary Stenting (CRISP Stent) study demonstrated that remote ischemic preconditioning reduced procedural symptoms, ECG ST-segment deviation, and cardiac troponin I release after elective PCI and reduced the major adverse cardiac and cerebral event (MACCE) rate at 6 months. We were interested to confirm if this early benefit in MACCE rate in the remote ischemic preconditioning group was sustained long-term.

21 mayo 2013

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Coronary Artery Disease. Assessment of Coronary Artery Stenosis by Coronary Angiography A Head-to-Head Comparison With Pathological Coronary Artery Anatomy

Song Jiangping, MD, PhD*, Zheng Zhe, MD, PhD*, Wang Wei, MD, PhD, Song Yunhu, MD, Huang Jie, MD, PhD, Wang Hongyue, MD, Zhao Hong, MD and Hu Shengshou, MD, PhD

Background: Conventional coronary angiography (CCA) has been considered as a gold standard for the diagnosis of coronary artery diseases; however, its diagnostic accuracy is still unknown.

28 mayo 2013

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Coronary Artery Disease. Long-term Morphofunctional Remodeling of Internal Thoracic Artery Grafts. A Frequency-Domain Optical Coherence Tomography Study

Italo Porto, MD, Mario Gaudino, MD, Giovanni Luigi De Maria, MD, Luca Di Vito, MD, Rocco Vergallo, MD, Piergiorgio Bruno, MD, Giorgia Bonalumi, MD, Francesco Prati, MD, Leonardo Bolognese, MD, Filippo Crea, MD and Massimo Massetti, MD

Background: Internal thoracic arteries (ITAs) are frequently anastomosed to the coronary circulation for bypass grafting. The purpose of this research was to investigate in vivo the long-term morphofunctional changes of ITAs after their use as coronary artery bypass conduits, by comparing the morphological features and vasoreactivity of the grafted left ITA (LITA) with the native, nonharvested right ITA (RITA) in the same patient.

04 junio 2014

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Pharmacology. Differential Effect of Ticagrelor Versus Prasugrel on Coronary Blood Flow Velocity in Patients With Non–ST-Elevation Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention. An Exploratory Study

Dimitrios Alexopoulos, MD, PhD, FESC, Athanasios Moulias, MD, Nikolaos Koutsogiannis, MD, Ioanna Xanthopoulou, MD, Apostolos Kakkavas, MD, Eleni Mavronasiou, MD, Periklis Davlouros, MD and George Hahalis, MD, PhD

Background: Prasugrel and ticagrelor provide a superior anti-ischemic action than clopidogrel, with some of ticagrelor’s benefits possibly attributed to adenosine-mediated mechanisms. We aimed to compare the effect of maintenance dose of ticagrelor versus prasugrel on coronary blood flow velocity (CBFV) during increasing doses of intravenously administered adenosine.

29 abril 2014

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Coronary Hemodynamics. Physiological Basis and Long-Term Clinical Outcome of Discordance Between Fractional Flow Reserve and Coronary Flow Velocity Reserve in Coronary Stenoses of Intermediate Severity

Tim P. van de Hoef, MD, Martijn A. van Lavieren, MSc, Peter Damman, MD, PhD, Ronak Delewi, MD, Martijn A. Piek, Steven A.J. Chamuleau, MD, PhD, Michiel Voskuil, MD, PhD, José P.S. Henriques, MD, PhD, Karel T. Koch, MD, PhD, Robbert J. de Winter, MD, PhD, Jos A.E. Spaan, PhD, Maria Siebes, PhD, Jan G.P. Tijssen, PhD, Martijn Meuwissen, MD, PhD and Jan J. Piek, MD, PhD

Background: Discordance between fractional flow reserve (FFR) and coronary flow velocity reserve (CFVR) may reflect important coronary pathophysiology but usually remains unnoticed in clinical practice. We evaluated the physiological basis and clinical outcome associated with FFR/CFVR discordance.

15 abril 2014

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Pharmacology. Heparin Monotherapy or Bivalirudin During Percutaneous Coronary Intervention in Patients With Non–ST-Segment–Elevation Acute Coronary Syndromes or Stable Ischemic Heart Disease. Results From the Evaluation of Drug-Eluting Stents and Ischemic Events Registry

Sripal Bangalore, MD, MHA, Michael J. Pencina, PhD, Neal S. Kleiman, MD and David J. Cohen, MD, MSc

Background: The use of bivalirudin versus unfractionated heparin monotherapy in patients without ST-segment–elevation myocardial infarction is not well defined.

20 mayo 2014

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Myocardial Infarction. Prognosis of Patients With Non–ST-Segment–Elevation Myocardial Infarction and Nonobstructive Coronary Artery Disease. Propensity-Matched Analysis From the Acute Catheterization and Urgent Intervention Triage Strategy Trial

David Planer, MD, MSc, Roxana Mehran, MD, E. Magnus Ohman, MD, Harvey D. White, DSc, Jonathan D. Newman, MD, MPH, Ke Xu, PhD and Gregg W. Stone, MD

Background: Troponin elevation is a risk factor for mortality in patients with non–ST-segment–elevation acute coronary syndromes. However, the prognosis of patients with troponin elevation and nonobstructive coronary artery disease (CAD) is unknown. Our objective was therefore to evaluate the impact of nonobstructive CAD in patients with non–ST-segment–elevation acute coronary syndromes and troponin elevation enrolled in the Acute Catheterization and Urgent Intervention Triage Strategy (ACUITY) trial.

04 junio 2013

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Coronary Interventions. Transulnar Compared With Transradial Artery Approach as a Default Strategy for Coronary Procedures. A Randomized Trial The Transulnar or Transradial Instead of Coronary Transfemoral Angiographies Study (The AURA of ARTEMIS Study)

George Hahalis, MD, PhD, Grigorios Tsigkas, MD, Ioanna Xanthopoulou, MD, Spyridon Deftereos, MD, Antonios Ziakas, MD, PhD, Konstantinos Raisakis, MD, Christos Pappas, MD, Aggelos Sourgounis, MD, Nikos Grapsas, MD, Periklis Davlouros, MD, PhD, Anastasia Galati, MD, Theodora-Eleni Plakomyti, MD, Panagiota Mylona, MD, Ioannis Styliadis, MD, PhD, Vlassis Pyrgakis, MD, FESC and Dimitrios Alexopoulos, MD, PhD, FESC

Background: The ulnar artery is rarely selected for coronary angiography or percutaneous coronary intervention despite the expanding use of the transradial approach. We aimed to establish noninferiority of a default transulnar relative to transradial approach in terms of feasibility and safety.

01 abril 2013

JACC. Comparison of Double Kissing Crush Versus Culotte Stenting for Unprotected Distal Left Main Bifurcation Lesions. Results From a Multicenter, Randomized, Prospective DKCRUSH-III Study

Shao-Liang Chen, MD⁎; Bo Xu, MBBS†; Ya-Ling Han, MD‡; Imad Sheiban, MD§; Jun-Jie Zhang, MD⁎; Fei Ye, MD⁎; Tak W. Kwan, MD∥; Chitprapai Paiboon, MD¶; Yu-Jie Zhou, MD#; Shu-Zheng Lv, MD#; George D. Dangas, MD⁎⁎; Ya-Wei Xu, MD††; Shang-Yu Wen, MD‡‡; Lang Hong, MD§§; Rui-Yan Zhang, MD∥∥; Hai-Chang Wang, MD¶¶; Tie-Ming Jiang, MD##; Yan Wang, MD⁎⁎⁎; Fang Chen, MD⁎⁎; Zu-Yi Yuan, MD†††; Wei-Min Li, MD‡‡‡; Martin B. Leon, MD§§§

Objectives: The study aimed to investigate the difference in major adverse cardiac event (MACE) at 1-year after double kissing (DK) crush versus Culotte stenting for unprotected left main coronary artery (UPLMCA) distal bifurcation lesions.

01 abril 2013

JACC. Outcome of Combined Stenotic and Regurgitant Aortic Valve Disease

Robert Zilberszac, MD⁎; Harald Gabriel, MD⁎; Michael Schemper, PhD†; David Zahler, MD⁎; Martin Czerny, MD‡; Gerald Maurer, MD⁎; Raphael Rosenhek, MD⁎

Objectives: This study sought to describe the natural history of combined stenotic and regurgitant aortic valve disease.

01 abril 2013

JACC. The Year in Interventional Cardiology

Simon R. Dixon, MBChB; Robert D. Safian, MD

We are delighted to provide readers of the Journal with this review of major scientific work published or presented as a late-breaking trial in 2012. We hope that the paper will provide a broad overview for general cardiologists, as well as a framework for more detailed study for those interested in interventional cardiology.

01 abril 2013

JACC. Transcatheter Aortic Valve Implantation for Pure Severe Native Aortic Valve Regurgitation

David A. Roy, MD⁎; Ulrich Schaefer, MD, PhD†; Victor Guetta, MD‡; David Hildick-Smith, MD§; Helge Möllmann, MD∥; Nicholas Dumonteil, MD¶; Thomas Modine, MD#; Johan Bosmans, MD⁎⁎; Anna Sonia Petronio, MD††; Neil Moat, MBBS, MS‡‡; Axel Linke, MD§§; Cesar Moris, MD∥∥; Didier Champagnac, MD¶¶; Radoslaw Parma, MD, PhD##; Andrzej Ochala, MD##; Diego Medvedofsky, MD‡; Tiffany Patterson, MD‡‡; Felix Woitek, MD§§; Marjan Jahangiri, MD⁎; Jean-Claude Laborde, MD⁎; Stephen J. Brecker, MD⁎

Objectives: This study sought to collect data and evaluate the anecdotal use of transcatheter aortic valve implantation (TAVI) in pure native aortic valve regurgitation (NAVR) for patients who were deemed surgically inoperable

01 abril 2013

JACC. Incidence, Predictors, and Outcomes of Aortic Regurgitation After Transcatheter Aortic Valve Replacement. Meta-Analysis and Systematic Review of Literature

Ganesh Athappan, MD⁎; Eshan Patvardhan, MD⁎; E. Murat Tuzcu, MD⁎; Lars Georg Svensson, MD, PhD‡; Pedro A. Lemos, MD§; Chiara Fraccaro, MD, PhD‖; Giuseppe Tarantini, MD, PhD‖; Jan-Malte Sinning, MD‖; Georg Nickenig, MD¶; Davide Capodanno, MD, PhD#; Corrado Tamburino, MD, PhD#; Azeem Latib, MD⁎⁎; Antonio Colombo, MD⁎⁎; Samir R. Kapadia, MD⁎

Objectives: This study was designed to establish the incidence, impact, and predictors of post-transcatheter aortic valve replacement (TAVR) aortic regurgitation (AR).

01 abril 2013

JACC. Safety and Feasibility of Robotic Percutaneous Coronary Intervention. PRECISE (Percutaneous Robotically-Enhanced Coronary Intervention) Study

Giora Weisz, MD⁎; D. Christopher Metzger, MD†; Ronald P. Caputo, MD‡; Juan A. Delgado, MD§; J. Jeffrey Marshall, MD∥; George W. Vetrovec, MD¶; Mark Reisman, MD#; Ron Waksman, MD⁎⁎; Juan F. Granada, MD§; Victor Novack, MD, PhD††; Jeffrey W. Moses, MD⁎; Joseph P. Carrozza, MD‡‡

Objectives: The aim of this study was to evaluate the safety as well as the clinical and technical effectiveness of robotic-assisted percutaneous coronary intervention.

01 abril 2013

JACC. Impact of Repeat Myocardial Revascularization on Outcome in Patients With Silent Ischemia After Previous Revascularization

Nael Aldweib, MD⁎; Kazuaki Negishi, MD, PhD⁎; Rory Hachamovitch, MD, MS⁎; Wael A. Jaber, MD⁎; Sinziana Seicean, MD, PhD, MPH⁎; Thomas H. Marwick, MD, PhD, MPH†

Objectives: This study sought to compare the survival of asymptomatic patients with previous revascularization and ischemia, who subsequently underwent repeat revascularization or medical therapy (MT).

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