01 octubre 2013

RADIOLOGY. Abdominal Aortic Atherosclerosis at MR Imaging Is Associated with Cardiovascular Events: The Dallas Heart Study

Christopher D. Maroules, MD, , Eric Rosero, MD, , Colby Ayers, MS, , Ronald M. Peshock, MD, and , Amit Khera, MD, MSc

The burden of coronary and cerebrovascular atherosclerotic disease has been closely linked to adverse cardiovascular outcomes, but less is known about asymptomatic aortic atherosclerosis. Aortic atherosclerosis has a long subclinical phase and can be assessed by measuring aortic plaque burden and aortic wall thickness (1,2). Both aortic plaque burden and aortic wall thickness can be directly and noninvasively quantified with good reproducibility by using high-spatial-resolution, black-blood magnetic resonance (MR) imaging (3–5). Noninvasive screening tests for subclinical aortic atherosclerosis may offer new insights into atherogenesis within different vascular beds and may help refine traditional cardiovascular risk stratification guidelines.

01 agosto 2014

ORIGINAL. IMPORTANCIA DE LA DETERMINACION DE LOS NIVELES DE VITAMINA D EN EL SINDROME CORONARIO AGUDO

Luciano Consuegra Sánchez, Leticia Jaulent Huertas

La vitamina D es la vitamina principal encargada de la regulación del metabolismo del calcio-fósforo y de la mineralización ósea. La vitamina D se presenta en dos formas: vitamina D2 (ergocalciferol) y vitamina D3 (colecalciferol). La Vitamina D2, se encuentra en las plantas y es producto de la radiación ultravioleta (UVB) de 290 a 315 mm de longitud de onda o puede ser ingerida como complemento o en los alimentos enriquecidos. La vitamina D3 es un producto de la radiación UVB de 7-dehidrocolesterol, de síntesis endógena en la epidermis humana o se obtiene de la ingesta de alimentos como aceite de pescado o alimentos enriquecidos

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01 junio 2013

JACC. A Novel Tool for Reliable and Accurate Prediction of Renal Complications in Patients Undergoing Percutaneous Coronary Intervention

Hitinder S. Gurm, MD*; Milan Seth, MS*; Judith Kooiman, MSc†; David Share, MD‡

Objectives: The aim of the study was to develop and validate a tool for predicting risk of contrast-induced nephropathy (CIN) in patients undergoing contemporary percutaneous coronary intervention (PCI).

01 junio 2013

JACC. Additive Value of Semiautomated Quantification of Coronary Artery Disease Using Cardiac Computed Tomographic Angiography to Predict Future Acute Coronary Syndrome

Mathijs O. Versteylen, MD*; Bas L. Kietselaer, MD, PhD*; Pieter C. Dagnelie, MS, PhD‡; Ivo A. Joosen, MD*; Admir Dedic, MD§; Rolf H. Raaijmakers, RT¶; Joachim E. Wildberger, MD, PhD†; Koen Nieman, MD, PhD§; Harry J. Crijns, MD, PhD*; Wiro J. Niessen, MS, PhD#; Mat J. Daemen, MD, PhD††; Leonard Hofstra, MD, PhD*

Objectives: The purpose of this study was to investigate whether the use of a semiautomated plaque quantification algorithm (reporting volumetric and geometric plaque properties) provides additional prognostic value for the development of acute coronary syndromes (ACS) as compared with conventional reading from cardiac computed tomography angiography (CCTA).

01 junio 2013

JACC. The Transaortic Approach for Transcatheter Aortic Valve Replacement. Initial Clinical Experience in the United States

Joel A. Lardizabal, MD; Brian P. O´Neill, MD; Harit V. Desai, MD; Conrad J. Macon, MD; Alexis P. Rodriguez, MD; Claudia A. Martinez, MD; Carlos E. Alfonso, MD; Martin S. Bilsker, MD; Roger G. Carillo, MD; Mauricio G. Cohen, MD; Alan W. Heldman, MD; William W. O´Neill, MD; Donald B. Williams, MD

Objectives: This study sought to investigate the technical feasibility and safety of the transaortic (TAO) transcatheter aortic valve replacement (TAVR) approach in patients not eligible for transfemoral (TF) access by using a device commercially available in the United States.

01 junio 2013

JACC. Clinical Outcome Following Stringent Discontinuation of Dual Antiplatelet Therapy After 12 Months in Real-World Patients Treated With Second-Generation Zotarolimus-Eluting Resolute and Everolimus-Eluting Xience V Stents. 2-Year Follow-Up of the Randomized TWENTE Trial

Kenneth Tandjung, MD∗; Hanim Sen, MD∗; Ming Kai Lam, MD∗; Mounir W.Z. Basalus, MD∗; J. (Hans) W. Louwerenburg, MD∗; Martin G. Stoel, MD∗; K. Gert van Houwelingen, MD∗; Frits H.A.F. de Man, MD, PhD∗; Gerard C.M. Linssen, MD, PhD†; Salah A.M. Saïd, MD, PhD‡; Mark B. Nienhuis, MD, PhD§; Marije M. Löwik, PhD∗; Patrick M.J. Verhorst, MD, PhD∗; Job van der Palen, PhD⋮; Clemens von Birgelen, MD, PhD∗

Objectives: The aim of this study was to assess the safety and efficacy of the implantation of Resolute zotarolimus-eluting stents (ZES) (Medtronic Inc., Santa Rosa, California) and Xience V everolimus-eluting stents (EES) (Abbott Vascular, Santa Clara, California) following strict discontinuation of dual antiplatelet therapy (DAPT) after 12 months.

01 junio 2013

JACC. Comparison of Transcatheter and Surgical Aortic Valve Replacement in Severe Aortic Stenosis. A Longitudinal Study of Echocardiography Parameters in Cohort A of the PARTNER Trial (Placement of Aortic Transcatheter Valves)

Rebecca T. Hahn, MD∗; Philippe Pibarot, DVM, PhD‡; William J. Stewart, MD§; Neil J. Weissman, MD⋮; Deepika Gopalakrishnan, MD¶; Martin G. Keane, MD#; Saif Anwaruddin, MD#; Zuyue Wang, MD⋮; Martin Bilsker, MD∗∗; Brian R. Lindman, MD††; Howard C. Herrmann, MD#; Susheel K. Kodali, MD∗; Raj Makkar, MD‡‡; Vinod H. Thourani, MD§§; Lars G. Svensson, MD§; Jodi J. Akin, MS⋮⋮; William N. Anderson, PhD⋮⋮; Martin B. Leon, MD∗; Pamela S. Douglas, MD¶¶

Objectives: This study sought to compare echocardiographic findings in patients with critical aortic stenosis following surgical aortic valve replacement (SAVR) or transcatheter aortic valve replacement (TAVR).

01 junio 2013

JACC. One-Stop Hybrid Coronary Revascularization Versus Coronary Artery Bypass Grafting and Percutaneous Coronary Intervention for the Treatment of Multivessel Coronary Artery Disease. 3-Year Follow-Up Results From a Single Institution

Liuzhong Shen, MD∗; Shengshou Hu, MD∗; Haoran Wang, MD∗; Hui Xiong, MD∗; Zhe Zheng, MD∗; Lihuan Li, MD‡; Bo Xu, MD§; Hongbing Yan, MD§; Runlin Gao, MD§

Objectives This study sought to compare midterm clinical outcomes of 1-stop hybrid coronary revascularization (HCR) with coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) for the treatment of multivessel coronary artery disease.

01 junio 2013

JACC. Left Atrial Appendage Closure With the Watchman Device in Patients With a Contraindication for Oral Anticoagulation. The ASAP Study (ASA Plavix Feasibility Study With Watchman Left Atrial Appendage Closure Technology)

Vivek Y. Reddy, MD∗; Sven Möbius-Winkler, MD†; Marc A. Miller, MD∗; Petr Neuzil, MD, PhD‡; Gerhard Schuler, MD†; Jens Wiebe, MD§; Peter Sick, MD⋮; Horst Sievert, MD§

Objectives: The purpose of this study was to assess the safety and efficacy of left atrial appendage (LAA) closure in nonvalvular atrial fibrillation (AF) patients ineligible for warfarin therapy.

01 junio 2014

EUROPEAN HEART JOURNAL. CardioPulse Articles. The future of valves for percutaneous insertion

Francesco Maisano MD FESC, Fabian Nietlispach MD

Transcatheter valve interventions are the more advanced and successful evolution of conventional cardiac surgery. Before the introduction of the heart–lung machine, heart surgery was performed on the beating heart, as in the case of digital commissurotomy. Open-heart interventions have been crucial in understanding valve disease and to developing advanced therapeutic solutions.

10 septiembre 2013

EUROPEAN HEART JOURNAL. The German Aortic Valve Registry (GARY): in-hospital outcome

Christian W. Hamm*, Helge Möllmann, David Holzhey, Andreas Beckmann, Christof Veit, Hans-Reiner Figulla, J. Cremer, Karl-Heinz Kuck, Rüdiger Lange, Ralf Zahn, Stefan Sack, Gerhard Schuler, Thomas Walther, Friedhelm Beyersdorf, Michael Böhm, Gerd Heusch, Anne-Kathrin Funkat, Thomas Meinertz, Till Neumann, Konstantinos Papoutsis, Steffen Schneider, Armin Welz, Friedrich W. Mohr, for the GARY-Executive Board

Background: Aortic stenosis is a frequent valvular disease especially in elderly patients. Catheter-based valve implantation has emerged as a valuable treatment approach for these patients being either at very high risk for conventional surgery or even deemed inoperable. The German Aortic Valve Registry (GARY) provides data on conventional and catheter-based aortic procedures on an all-comers basis.

07 junio 2014

EUROPEAN HEART JOURNAL. CardioPulse Articles. Warfarin increases stroke risk in atrial fibrillation

Andros Tofield

Atrial fibrillation (AF) patients in the first 30 days of use. Patients with AF have nearly double the risk of suffering a stroke in the first 30 days after starting warfarin compared with non-users, according to a study of over 70 000 patients.

06 marzo 2014

EUROPEAN HEART JOURNAL. Contrast-induced acute kidney injury after primary percutaneous coronary intervention: results from the HORIZONS-AMI substudy

Amar Narula1, Roxana Mehran2,3,*, Giora Weisz3,4,5, George D. Dangas2,3, Jennifer Yu2, Philippe Généreux3,4,6, Eugenia Nikolsky7, Sorin J. Brener3,8, Bernhard Witzenbichler9, Giulio Guagliumi10, Avery E. Clark11, Martin Fahy3, Ke Xu3, Bruce R. Brodie12 and Gregg W. Stone3,4

Aim: We sought to examine the short- and long-term outcomes of patients who developed contrast-induced acute kidney injury (CI-AKI; defined as an increase in serum creatinine of ≥0.5 mg/dL or a 25% relative rise within 48 h after contrast exposure) from the large-scale HORIZONS-AMI trial.

19 noviembre 2013

EUROPEAN HEART JOURNAL. Computed tomography angiography and perfusion to assess coronary artery stenosis causing perfusion defects by single photon emission computed tomography: the CORE320 study

Carlos E. Rochitte4,†, Richard T. George1,†, Marcus Y. Chen5, Armin Arbab-Zadeh1, Marc Dewey6, Julie M. Miller1, Hiroyuki Niinuma7,8, Kunihiro Yoshioka7, Kakuya Kitagawa9, Shiro Nakamori9, Roger Laham10, Andrea L. Vavere1, Rodrigo J. Cerci1, Vishal C. Mehra1, Cesar Nomura11, Klaus F. Kofoed12, Masahiro Jinzaki13, Sachio Kuribayashi13, Albert de Roos14, Michael Laule6, Swee Yaw Tan15, John Hoe16, Narinder Paul17, Frank J. Rybicki3, Jeffery A. Brinker1, Andrew E. Arai5, Christopher Cox2, Melvin E. Clouse10, Marcelo F. Di Carli3 and Joao A.C. Lima1,*

Aims: To evaluate the diagnostic power of integrating the results of computed tomography angiography (CTA) and CT myocardial perfusion (CTP) to identify coronary artery disease (CAD) defined as a flow limiting coronary artery stenosis causing a perfusion defect by single photon emission computed tomography (SPECT).

19 febrero 2014

EUROPEAN HEART JOURNAL. Coronary computed tomography angiography with model-based iterative reconstruction using a radiation exposure similar to chest X-ray examination

Tobias A. Fuchs†, Julia Stehli†, Sacha Bull, Svetlana Dougoud, Olivier F. Clerc, Bernhard A. Herzog, Ronny R. Buechel, Oliver Gaemperli and Philipp A. Kaufmann*

Aims: To evaluate the feasibility and image quality of coronary computed tomography angiography (CCTA) acquisition with a submillisievert fraction of effective radiation dose using model-based iterative reconstruction (MBIR) for noise reduction.