01 abril 2016

NEUROSURGERY. Stereotactic Radiosurgery for Arteriovenous Malformations: The Effect of Treatment Period on Patient Outcomes

Pollock, Bruce E. MD; Link, Michael J. MD; Stafford, Scott L. MD; Garces, Yolanda I. MD; Foote, Robert L. MD

BACKGROUND: Stereotactic radiosurgery (SRS) has been performed on patients with cerebral arteriovenous malformations (AVMs) for over 40 years.

01 abril 2016

NEUROSURGERY. Association of Hemodynamic Factors With Intracranial Aneurysm Formation and Rupture: Systematic Review and Meta-analysis

Can, Anil MD; Du, Rose MD, PhD

BACKGROUND: Recent evidence suggests a link between the magnitude and distribution of hemodynamic factors and the formation and rupture of intracranial aneurysms. However, there are many conflicting results.

01 abril 2016

NEUROSURGERY. Recurrence of Cerebral Arteriovenous Malformations Following Resection in Adults: Does Preoperative Embolization Increase the Risk?

Ivanov, Alexander A. MD; Alaraj, Ali MD; Charbel, Fady T. MD; Aletich, Victor MD; Amin-Hanjani, Sepideh MD

BACKGROUND: Complete surgical resection of arteriovenous malformations (AVMs), documented by postoperative angiography, is generally felt to represent cure, obviating the need for long-term follow-up imaging. Although AVM recurrence has been reported in the pediatric population, this phenomenon has only rarely been documented in adults. Recurrence after treatment solely with embolization, however, has been reported more frequently. Thus, patients undergoing multimodal therapy with surgery following preoperative embolization may also be at higher risk for recurrence.

01 mayo 2016

NEUROSURGERY. Multisession Radiosurgery for Sellar and Parasellar Benign Meningiomas: Long-term Tumor Growth Control and Visual Outcome

Marchetti, Marcello MD; Bianchi, Stefania MD; Pinzi, Valentina MD; Tramacere, Irene PhD; Fumagalli, Maria Luisa PhD; Milanesi, Ida Maddalena MD; Ferroli, Paolo MD; Franzini, Angelo MD; Saini, Marco MD; DiMeco, Francesco MD; Fariselli, Laura MD

BACKGROUND: Concern about radiation-induced optic neuropathy (RION) has governed recent thinking about the role of radiation therapy in the treatment of meningiomas involving the anterior optic pathways. Despite this concern, during the last few years, the use of radiosurgery for such lesions has increased steadily.

01 mayo 2016

NEUROSURGERY. Lower Risk of Intracranial Arteriovenous Malformation Hemorrhage in Patients With Hereditary Hemorrhagic Telangiectasia

Yang, Wuyang MD; Liu, Ann BA; Hung, Alice L. BA; Braileanu, Maria MD; Wang, Joanna Y. BA; Caplan, Justin M. MD; Colby, Geoffrey P. MD, PhD; Coon, Alexander L. MD; Tamargo, Rafael J. MD; Ahn, Edward S. MD; Huang, Judy MD

BACKGROUND: Patients diagnosed with hereditary hemorrhagic telangiectasia (HHT) are at risk of developing intracranial arteriovenous malformations (AVM). However, the clinical manifestations and natural history of HHT-related AVMs remain unclear due to the rarity of these lesions.

23 abril 2016

THE LANCET. Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials

Prof Mayank Goyal, MD, Bijoy K Menon, MD, Wim H van Zwam, MD, Prof Diederik W J Dippel, MD, Prof Peter J Mitchell, MBBS, Prof Andrew M Demchuk, MD, Prof Antoni Dávalos, MD, Prof Charles B L M Majoie, MD, Prof Aad van der Lugt, MD, Maria A de Miquel, MD, Prof Geoffrey A Donnan, MD, Prof Yvo B W E M Roos, MD, Prof Alain Bonafe, MD, Reza Jahan, MD, Prof Hans-Christoph Diener, MD, Lucie A van den Berg, MD, Prof Elad I Levy, MD, Olvert A Berkhemer, MD, Vitor M Pereira, MD, Jeremy Rempel, MD, Mònica Millán, MD, Prof Stephen M Davis, MD, Prof Daniel Roy, MD, John Thornton, MD, Luis San Román, MD, Marc Ribó, MD, Debbie Beumer, MD, Prof Bruce Stouch, PhD, Scott Brown, PhD, Bruce C V Campbell, MD, Prof Robert J van Oostenbrugge, MD, Prof Jeffrey L Saver, MD, Prof Michael D Hill, MD, Dr Tudor G Jovin, MD for the HERMES collaborators

Background: In 2015, five randomised trials showed efficacy of endovascular thrombectomy over standard medical care in patients with acute ischaemic stroke caused by occlusion of arteries of the proximal anterior circulation. In this meta-analysis we, the trial investigators, aimed to pool individual patient data from these trials to address remaining questions about whether the therapy is efficacious across the diverse populations included.

26 marzo 2016

THE LANCET. Association between age and risk of stroke or death from carotid endarterectomy and carotid stenting: a meta-analysis of pooled patient data from four randomised trials

Prof George Howard, DrPH, Prof Gary S Roubin, MD, Prof Olav Jansen, MD, Prof Jeroen Hendrikse, MD, Prof Alison Halliday, MD, Prof Gustav Fraedrich, MD, Prof Hans-Henning Eckstein, MD, David Calvet, MD, Richard Bulbulia, MD, Leo H Bonati, MD, Prof Jean-Pierre Becquemin, MD, Prof Ale Algra, MD, Prof Martin M Brown, MD, Prof Peter A Ringleb, MD, Prof Thomas G Brott, MD, Prof Jean-Louis Mas, MD on behalf of the Carotid Stenting Trialists´ Collaboration

Background: Age was reported to be an effect-modifier in four randomised controlled trials comparing carotid artery stenting (CAS) and carotid endarterectomy (CEA), with better CEA outcomes than CAS outcomes noted in the more elderly patients. We aimed to describe the association of age with treatment differences in symptomatic patients and provide age-specific estimates of the risk of stroke and death within narrow (5 year) age groups.

01 marzo 2016

SPRINGER. Prediction of cerebral hyperperfusion syndrome after carotid artery stenting by CT perfusion imaging with acetazolamide challenge

Tomohide Yoshie , Toshihiro Ueda, Tatsuro Takada, Shinji Nogoshi, Takayuki Fukano, Yasuhiro Hasegawa

Introduction: Cerebral hyperperfusion syndrome (HPS) is an uncommon but serious complication of carotid artery stenting (CAS). The purpose of this study was to investigate the efficacy of CT perfusion imaging (CTP) with acetazolamide challenge to identify patients at risk for HPS after CAS.

01 marzo 2016

SPRINGER. Incidence of delayed ipsilateral intraparenchymal hemorrhage after stent-assisted coiling of intracranial aneurysms in a high-volume single center

Yasha Kayan, Josser E. Delgado Almandoz, Jennifer L. Fease, Kira Tran, Anna M. Milner, Jill M. Scholz

Introduction: Delayed ipsilateral intraparenchymal hemorrhage (IPH) has been reported following technically successful treatment of intracranial aneurysms using flow-diverting stents in up to 8.5 % of patients. We report a similar, though less frequent phenomenon in the setting of stent-assisted coil embolization.

01 marzo 2016

SPRINGER. Safety, efficacy, and short-term follow-up of the use of Pipeline™ Embolization Device in small (<2.5mm) cerebral vessels for aneurysm treatment: single institution experience

Ajit S. Puri, Francesco Massari, Takumi Asai, Miklos Marosfoi, Peter Kan, Samuel Y. Hou, Mary Howk, Mary Perras, Christopher Brooks, Frederic Clarencon, Matthew J. Gounis, Ajay K. Wakhloo

Introduction: Flow diversion is being increasingly used to treat cerebral aneurysms. We present our experience using these stents to treat aneurysms distal to the circle of Willis with parent arteries smaller than 2.5 mm.

01 marzo 2016

SPRINGER. Endovascular treatment of intracranial infectious aneurysms

Asim Esenkaya, Fatih Duzgun, Celal Cinar, Halil Bozkaya, Cenk Eraslan, Erkin Ozgiray, Ismail Oran

Introduction: Intracranial infectious aneurysm (IIA) accounts for less than 5 % of all intracranial aneurysms. The aim of this study was to evaluate the role of endovascular treatment for IIA.

01 marzo 2016

SPRINGER. Ruptured basilar artery perforator aneurysms—treatment regimen and long-term follow-up in eight cases

Robert Forbrig, Bernd Eckert, Lorenz Ertl, Maximilian Patzig, Christian Brem, Christian Vollmar, Joachim Röther, Niklas Thon, Hartmut Brückmann, Gunther Fesl

Introduction: Basilar artery (BA) perforator aneurysms may lead to severe subarachnoid hemorrhage (SAH). The acute management is uncertain. The anatomic approach is challenging both for coiling and clipping, and flow diverter stenting may be dangerous due to the required antiplatelet therapy. We report on our experiences in eight patients.

01 abril 2016

SPRINGER. Testing flow diversion in animal models: a systematic review

Robert Fahed, Jean Raymond , Célina Ducroux, Jean-Christophe Gentric, Igor Salazkin, Daniela Ziegler, Guylaine Gevry, Tim E. Darsaut

Introduction: Flow diversion (FD) is increasingly used to treat intracranial aneurysms. We sought to systematically review published studies to assess the quality of reporting and summarize the results of FD in various animal models.

01 abril 2016

SPRINGER. Woven Endobridge (WEB) device for endovascular treatment of complex unruptured aneurysms—a single center experience

Stephanie Lescher , Richard du Mesnil de Rochemont, Joachim Berkefeld

Introduction: The introduction of the Woven Endobridge (WEB) device increases the feasibility of endovascular treatment of wide-neck bifurcation aneurysms with limitations given by currently available sizes and shapes of the device. Parallel to other studies, we used the new device for selected patients who were no optimal candidates for established techniques like neurosurgical clipping or endovascular coiling. We aimed to report the angiographic and clinical results of WEB implantations or combinations between WEB and coiling or intracranial stents.

11 abril 2016

SPRINGER. Duplex-assisted carotid artery stenting without administration of contrast medium for patients with chronic kidney disease or allergic reaction

Takashi Mizowaki, Atsushi Fujita, Taichiro Imahori, Atsushi Uyama, Satoshi Inoue, Masaaki Kohta, Hirotoshi Hamaguchi, Takashi Sasayama, Kohkichi Hosoda, Eiji Kohmura

Introduction: We aimed to investigate the safety and feasibility of duplex-assisted carotid artery stenting (CAS) without administration of contrast medium for the prevention of adverse reactions.