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ESTUDIOS


18 noviembre 2014

STROKE. Clinical Sciences. Intraluminal Thrombus, Intraplaque Hemorrhage, Plaque Thickness, and Current Smoking Optimally Predict Carotid Stroke

J. Scott McNally, MD, PhD; Michael S. McLaughlin, MD; Peter J. Hinckley, BS; Scott M. Treiman; Gregory J. Stoddard, MBA, MPH, PhD; Dennis L. Parker, PhD; Gerald S. Treiman, MD

Background and Purpose: Intraplaque hemorrhage (IPH) is associated with acute and future stroke. IPH is also associated with lumen markers of stroke risk including stenosis, plaque thickness, and ulceration. Whether IPH adds further predictive value to these other variables is unknown. The purpose of this study was to determine whether IPH improves carotid-source stroke prediction.

06 noviembre 2014

STROKE. Brief Report. Cerebral Venous Thrombosis in the Absence of Headache

Jonathan M. Coutinho, MD, PhD; Jan Stam, MD, PhD; Patricia Canhão, MD, PhD; Fernando Barinagarrementeria, MD; Marie-Germaine Bousser, MD, PhD; José M. Ferro, MD, PhD; on behalf of the ISCVT Investigators

Background and Purpose: Although headache is the most common symptom in cerebral venous thrombosis, 5% to 30% of patients do not report headache at baseline. Characteristics of these patients have not been investigated.

13 enero 2015

STROKE. Clinical Sciences. Influence of Intracerebral Hemorrhage Location on Incidence, Characteristics, and Outcome

Neshika Samarasekera, MRCP; Arthur Fonville†; Christine Lerpiniere, RGN; Andrew J. Farrall, MD; Joanna M. Wardlaw, MD; Philip M. White, MD; Colin Smith, MD; Rustam Al-Shahi Salman, PhD; for the Lothian Audit of the Treatment of Cerebral Haemorrhage Collaborators

Background and Purpose: The characteristics of intracerebral hemorrhage (ICH) may vary by ICH location because of differences in the distribution of underlying cerebral small vessel diseases. Therefore, we investigated the incidence, characteristics, and outcome of lobar and nonlobar ICH.

08 enero 2015

STROKE. Clinical Sciences. Is Prophylactic Anticoagulation for Deep Venous Thrombosis Common Practice After Intracerebral Hemorrhage?

Shyam Prabhakaran, MD, MS; Patricia Herbers, MS; Jane Khoury, PhD; Opeolu Adeoye, MD; Pooja Khatri, MD; Simona Ferioli, MD; Dawn O. Kleindorfer, MD

Background and Purpose: Prophylactic anticoagulation for deep venous thrombosis prevention after intracerebral hemorrhage (ICH) is safe. Current guidelines recommend prophylactic anticoagulation after cessation of hematoma growth. We aimed to evaluate nationwide trends in deep venous thrombosis prophylaxis after ICH.

06 enero 2015

STROKE. Brief Report. Plaque Components in Symptomatic Moderately Stenosed Carotid Arteries Related to Cerebral Infarcts. The Plaque At RISK Study

Alexandra A.J. de Rotte, MD; Martine T.B. Truijman, MD; Anouk C. van Dijk, MD; Madieke I. Liem, MD; Floris H.B.M. Schreuder, MD; Anja G. van der Kolk, MD, PhD; Jelle R. de Kruijk, MD, PhD; Matt J.A.P. Daemen, MD, PhD; Anton F.W. van der Steen, PhD; Gert Jan de Borst, MD, PhD; Peter R. Luijten, PhD; Paul J. Nederkoorn, MD, PhD; Marianne Eline Kooi, PhD; Aad van der Lugt, MD, PhD; Jeroen Hendrikse, MD, PhD

Background and Purpose: Carotid plaque composition is a major determinant of cerebrovascular events. In the present analysis, we evaluated the relationship between intraplaque hemorrhage (IPH) and a thin/ruptured fibrous cap (TRFC) in moderately stenosed carotid arteries and cerebral infarcts on MRI in the ipsilateral hemisphere.

23 diciembre 2014

STROKE. Brief Report. Comparing National Institutes of Health Stroke Scale Among a Stroke Team and Helicopter Emergency Medical Service Providers

Matthew R. Kesinger, BA; Denisse J. Sequeira, BA; Samantha Buffalini, RN(c); Francis X. Guyette, MD, MPH

Background and Purpose: The use of tissue-type plasminogen activator is limited to a maximum of 4.5 hours after symptom-onset. Endovascular recanalization may improve outcomes for large-vessel occlusions (LVO), but efficacy decreases with time from symptom-onset. A National Institutes of Health Stroke Scale (NIHSS) score ≥12 is predictive of LVOs and could be used to triage patients if appropriately used by prehospital providers. The NIHSS has been considered too complex and has not been validated in the prehospital setting.

14 enero 2016

SPRINGER. CT angiography and CT perfusion improve prediction of infarct volume in patients with anterior circulation stroke

Tom van Seeters, Geert Jan Biessels, L. Jaap Kappelle, Irene C. van der Schaaf, Jan Willem Dankbaar, Alexander D. Horsch, Joris M. Niesten, Merel J. A. Luitse, Charles B. L. M. Majoie, Jan Albert Vos, Wouter J. Schonewille, Marianne A. A. van Walderveen, Marieke J. H. Wermer, Lucien E. M. Duijm, Koos Keizer, Joseph C. J. Bot, Marieke C. Visser, Aad van der Lugt, Diederik W. J. Dippel, F. Oskar H. W. Kesselring, Jeannette Hofmeijer, Geert J. Lycklama à Nijeholt, Jelis Boiten, Willem Jan van Rooij, Paul L. M. de Kort, Yvo B. W. E. M. Roos, Frederick J. A. Meijer, C. Constantijn Pleiter, Willem P. T. M. Mali, Yolanda van der Graaf, Birgitta K. Velthuis, on behalf of the Dutch acute stroke study (DUST) investigators

Introduction: We investigated whether baseline CT angiography (CTA) and CT perfusion (CTP) in acute ischemic stroke could improve prediction of infarct presence and infarct volume on follow-up imaging.

03 septiembre 2015

AMERICAN JOURNAL OF NEURORADIOLOGY. Carotid Near-Occlusion: A Comprehensive Review, Part 2—Prognosis and Treatment, Pathophysiology, Confusions, and Areas for Improvement

E. Johansson and A.J. Fox

SUMMARY: In Part 1 of this review, the definition, terminology, and diagnosis of carotid near-occlusion were presented. Carotid near-occlusions (all types) showed a lower risk of stroke than other severe stenoses. However, emerging evidence suggests that the near-occlusion prognosis with full collapse (higher risk) differs from that without full collapse (lower risk). This systematic review presents what is known about carotid near-occlusion. In this second part, the foci are prognosis and treatment, pathophysiology, the current confusion about near-occlusion, and areas in need of future improvement.

08 octubre 2015

AMERICAN JOURNAL OF NEURORADIOLOGY. Diagnostic Impact of Bone-Subtraction CT Angiography for Patients with Acute Subarachnoid Hemorrhage

P. Aulbach, D. Mucha, K. Engellandt, K. Hädrich, M. Kuhn and R. von Kummer

BACKGROUND AND PURPOSE: Detection and evaluation of ruptured aneurysms is critical for choosing an appropriate endovascular or neurosurgical intervention. Our aim was to assess whether bone-subtraction CTA is capable of guiding treatment for cerebral aneurysms in patients with acute SAH and could replace DSA.

08 octubre 2015

AMERICAN JOURNAL OF NEURORADIOLOGY. Cerebral Perfusion Pressure is Maintained in Acute Intracerebral Hemorrhage: A CT Perfusion Study

A.S. Tamm, R. McCourt, B. Gould, M. Kate, J.C. Kosior, T. Jeerakathil, L.C. Gioia, D. Dowlatshahi, M.D. Hill, S.B. Coutts, A.M. Demchuk, B.H. Buck, D.J. Emery, A. Shuaib and K.S. Butcher on behalf of the ICH ADAPT Investigators

BACKGROUND AND PURPOSE: Although blood pressure reduction has been postulated to result in a fall in cerebral perfusion pressure in patients with intracerebral hemorrhage, the latter is rarely measured. We assessed regional cerebral perfusion pressure in patients with intracerebral hemorrhage by using CT perfusion source data.

22 octubre 2015

AMERICAN JOURNAL OF NEURORADIOLOGY. Osseous Pseudoprogression in Vertebral Bodies Treated with Stereotactic Radiosurgery: A Secondary Analysis of Prospective Phase I/II Clinical Trials

B. Amini, C.B. Beaman, J.E. Madewell, P.K. Allen, L.D. Rhines, C.E. Tatsui, N.M. Tannir, J. Li, P.D. Brown and A.J. Ghia

BACKGROUND AND PURPOSE: Osseous pseudoprogression on MR imaging can mimic true progression in lesions treated with spine stereotactic radiosurgery. Our aim was to describe the prevalence and time course of osseous pseudoprogression to assist radiologists in the assessment of patients after spine stereotactic radiosurgery.

27 agosto 2015

AMERICAN JOURNAL OF NEURORADIOLOGY. Carotid Near-Occlusion: A Comprehensive Review, Part 1—Definition, Terminology, and Diagnosis

E. Johansson and A.J. Fox

SUMMARY: Carotid near-occlusion is distal ICA luminal collapse beyond a tight stenosis, where the distal lumen should not be used for calculating percentage stenosis. Near-occlusion with full ICA collapse is well-known, with a threadlike lumen. However, near-occlusion without collapse is often subtle and can be overlooked as a usual severe stenosis. More than 10 different terms have been used to describe near-occlusion, sometimes causing confusion. This systematic review presents what is known about carotid near-occlusion. In this first part, the foci are definition, terminology, and diagnosis.

27 agosto 2015

AMERICAN JOURNAL OF NEURORADIOLOGY. A New Aneurysm Occlusion Classification after the Impact of Flow Modification

H.S. Cekirge and I. Saatci

SUMMARY: A new classification is proposed for cerebral aneurysms treated with any endovascular technique, for example, coiling with or without adjunctive devices, flow diversion, intrasaccular flow modifiers, or any combination of the above. Raymond-Roy Occlusion Classification is expanded with novel subgroups such as class 1 represents complete occlusion and is subdivided if a branch is integrated to, or originated from, the aneurysm sac; class 2 represents neck filling; class 3 represents incomplete occlusion with aneurysm filling as in the previous classification; and class 4 describes the immediate postoperative status after extra- or intrasaccular flow modification treatment. A new concept, “stable remodeling,” is included as class 5, which represents filling in the neck region that stays unchanged or reduced, as shown with at least 2 consecutive control angiographies, at least 6 months apart, for not <1 year, or the remodeled appearance of a dilated and/or tortuous vessel in continuation with the parent artery without sac filling.

30 octubre 2014

STROKE. Clinical Sciences. Influence of Age on Clinical and Revascularization Outcomes in the North American Solitaire Stent-Retriever Acute Stroke Registry

Alicia C. Castonguay, PhD; Osama O. Zaidat, MD, MS; Roberta Novakovic, MD; Thanh N. Nguyen, MD; M. Asif Taqi, MD; Rishi Gupta, MD; Chung-Huan J. Sun, MD; Coleman Martin, MD; William E. Holloway, MD; Nils Mueller-Kronast, MD; Joey E. English, MD; Italo Linfante, MD; Guilherme Dabus, MD; Tim W. Malisch, MD; Franklin A. Marden, MD; Hormozd Bozorgchami, MD; Andrew Xavier, MD; Ansaar T. Rai, MD; Michael T. Froehler, MD, PhD; Aamir Badruddin, MD; Michael G. Abraham, MD; Vallabh Janardhan, MD; Hashem Shaltoni, MD; Albert J. Yoo, MD; Alex Abou-Chebl, MD; Peng R. Chen, MD; Gavin W. Britz, MD; Ritesh Kaushal, MD; Ashish Nanda, MD; Mohammad A. Issa, MD; Raul G. Nogueira, MD

Background and Purpose: The Solitaire With the Intention for Thrombectomy (SWIFT) and thrombectomy revascularization of large vessel occlusions in acute ischemic stroke (TREVO 2) trial results demonstrated improved recanalization rates with mechanical thrombectomy; however, outcomes in the elderly population remain poorly understood. Here, we report the effect of age on clinical and angiographic outcome within the North American Solitaire-FR Stent-Retriever Acute Stroke (NASA) Registry.

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