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ESTUDIOS


01 julio 2016

NEUROSURGERY. Treatment of Distal Anterior Circulation Aneurysms With the Pipeline Embolization Device: A US Multicenter Experience

Lin, Ning MD; Lanzino, Giuseppe MD; Lopes, Demetrius K. MD; Arthur, Adam S. MD; Ogilvy, Christopher S. MD; Ecker, Robert D. MD; Dumont, Travis M. MD; Turner, Raymond D. IV MD; Gooch, M. Reid MD; Boulos, Alan S. MD; Kan, Peter MD, MPH; Snyder, Kenneth V. MD, PhD; Levy, Elad I. MD, MBA; Siddiqui, Adnan H. MD, PhD

BACKGROUND: Utilization of the Pipeline embolization device (PED) to treat distal carotid circulation aneurysms has not been well studied.

01 junio 2016

NEUROSURGERY. Low-grade Glioma Surgery in Intraoperative Magnetic Resonance Imaging: Results of a Multicenter Retrospective Assessment of the German Study Group for Intraoperative Magnetic Resonance Imaging

Coburger, Jan MD; Merkel, Andreas MD; Scherer, Moritz MD; Schwartz, Felix MD; Gessler, Florian MD; Roder, Constantin MD; Pala, Andrej MD; König, Ralph MD, PhD; Bullinger, Lars MD, PhD; Nagel, Gabriele MD, PhD; Jungk, Christine MD; Bisdas, Sotirios MD, PhD; Nabavi, Arya MD, PhD; Ganslandt, Oliver MD, PhD; Seifert, Volker MD, PhD; Tatagiba, Marcos MD, PhD; Senft, Christian MD, PhD; Mehdorn, Maximilian MD, PhD; Unterberg, Andreas W. MD, PhD; Rössler, Karl MD, PhD; Wirtz, Christian Rainer MD, PhD

BACKGROUND: The ideal treatment strategy for low-grade gliomas (LGGs) is a controversial topic. Additionally, only smaller single-center series dealing with the concept of intraoperative magnetic resonance imaging (iMRI) have been published.

10 diciembre 2015

AMERICAN JOURNAL OF NEURORADIOLOGY. Imaging, Intervention, and Workflow in Acute Ischemic Stroke: The Calgary Approach

C. Zerna, Z. Assis, C.D. d´Esterre, B.K. Menon and M. Goyal

SUMMARY: Five recently published clinical trials showed dramatically higher rates of favorable functional outcome and a satisfying safety profile of endovascular treatment compared with the previous standard of care in acute ischemic stroke with proximal anterior circulation artery occlusion. Eligibility criteria within these trials varied by age, stroke severity, imaging, treatment-time window, and endovascular treatment devices. This focused review provides an overview of the trial results and explores the heterogeneity in imaging techniques, workflow, and endovascular techniques used in these trials and the consequent impact on practice. Using evidence from these trials and following a case from start to finish, this review recommends strategies that will help the appropriate patient undergo a fast, focused clinical evaluation, imaging, and intervention.

24 septiembre 2015

AMERICAN JOURNAL OF NEURORADIOLOGY. Treatment of 213 Patients with Symptomatic Tarlov Cysts by CT-Guided Percutaneous Injection of Fibrin Sealant

K. Murphy, A.L. Oaklander, G. Elias, S. Kathuria and D.M. Long

BACKGROUND AND PURPOSE: There has been a steady progression of case reports and a small surgical series that report successful surgical treatment of Tarlov cysts with concomitant relief of patients´ symptoms and improvement in their neurological dysfunction, yet patients are still told that these lesions are asymptomatic by physicians. The purpose of this study was to analyze the efficacy and safety of intervention in 213 consecutive patients with symptomatic Tarlov cysts treated by CT-guided 2-needle cyst aspiration and fibrin sealing.

22 enero 2015

AMERICAN JOURNAL OF NEURORADIOLOGY. Reversible Cerebral Vasoconstriction Syndrome, Part 2: Diagnostic Work-Up, Imaging Evaluation, and Differential Diagnosis

T.R. Miller, R. Shivashankar, M. Mossa-Basha and D. Gandhi

SUMMARY: The diagnostic evaluation of a patient with reversible cerebral vasoconstriction syndrome integrates clinical, laboratory, and radiologic findings. Imaging plays an important role by confirming the presence of cerebral vasoconstriction; monitoring potential complications such as ischemic stroke; and suggesting alternative diagnoses, including CNS vasculitis and aneurysmal subarachnoid hemorrhage. Noninvasive vascular imaging, including transcranial Doppler sonography and MR angiography, has played an increasingly important role in this regard, though conventional angiography remains the criterion standard for the evaluation of cerebral artery vasoconstriction. Newer imaging techniques, including high-resolution vessel wall imaging, may help in the future to better discriminate reversible cerebral vasoconstriction syndrome from primary angiitis of the CNS, an important clinical distinction.

07 junio 2012

AMERICAN JOURNAL OF NEURORADIOLOGY. Safety of the Pipeline Embolization Device in Treatment of Posterior Circulation Aneurysms

T.J. Phillips, J.D. Wenderoth, C.C. Phatouros, H. Rice, T.P. Singh, L. Devilliers, V. Wycoco, S. Meckel and W. McAuliffe

BACKGROUND AND PURPOSE: The published results of treating internal carotid artery aneurysms with the PED do not necessarily apply to its use in the posterior circulation because disabling brain stem infarcts can be caused by occlusion of a single perforator. In this multicenter study, we assessed the safety of PED placement in the posterior circulation.

02 agosto 2012

AMERICAN JOURNAL OF NEURORADIOLOGY. Canadian Experience with the Pipeline Embolization Device for Repair of Unruptured Intracranial Aneurysms

C.J. O´Kelly, J. Spears, M. Chow, J. Wong, M. Boulton, A. Weill, R.A. Willinsky, M. Kelly and T.R. Marotta

BACKGROUND AND PURPOSE: Flow-diverting stents, such as the PED, have emerged as a novel means of treating complex intracranial aneurysms. This retrospective analysis of the initial Canadian experience provides insight into technical challenges, clinical and radiographic outcomes, and complication rates after the use of flow-diverting stents for unruptured aneurysms.

07 junio 2012

AMERICAN JOURNAL OF NEURORADIOLOGY. Intrasaccular Flow-Disruption Treatment of Intracranial Aneurysms: Preliminary Results of a Multicenter Clinical Study

L. Pierot, T. Liebig, V. Sychra, K. Kadziolka, F. Dorn, C. Strasilla, C. Kabbasch and J. Klisch

BACKGROUND AND PURPOSE: The endovascular treatment of intracranial aneurysms with unfavorable anatomy (large aneurysms, wide-neck) is frequently challenging and is also associated with a high incidence of significant recurrences. The WEB, an intrasaccular flow disrupter, was designed for use in this type of aneurysm. We report our early experience with this device in this multicenter study.

29 octubre 2014

AMERICAN JOURNAL OF NEURORADIOLOGY. International Retrospective Study of the Pipeline Embolization Device: A Multicenter Aneurysm Treatment Study

D.F. Kallmes, R. Hanel, D. Lopes, E. Boccardi, A. Bonafé, S. Cekirge, D. Fiorella, P. Jabbour, E. Levy, C. McDougall, A. Siddiqui, I. Szikora, H. Woo, F. Albuquerque, H. Bozorgchami, S.R. Dashti, J.E. Delgado Almandoz, M.E. Kelly, R. Turner IV, B.K. Woodward, W. Brinjikji, G. Lanzino and P. Lylyk

BACKGROUND AND PURPOSE: Flow diverters are increasingly used in the endovascular treatment of intracranial aneurysms. Our aim was to determine neurologic complication rates following Pipeline Embolization Device placement for intracranial aneurysm treatment in a real-world setting.

26 septiembre 2013

AMERICAN JOURNAL OF NEURORADIOLOGY. Endovascular Treatment of Middle Cerebral Artery Aneurysms with Flow Modification with the Use of the Pipeline Embolization Device

K. Yavuz, S. Geyik, I. Saatci and H.S. Cekirge

BACKGROUND AND PURPOSE: The Pipeline Embolization Device was reported to be safe and effective in the treatment of sidewall aneurysms, preserving the patency of the vessels covered by the construct. However, to date, the safety and efficacy of this device in treating bifurcation aneurysms remains unknown. We report our preliminary experience with the use of the Pipeline Embolization Device in the management of MCA aneurysms located at the bifurcations, including mid- and long-term follow-up data.

21 junio 2012

AMERICAN JOURNAL OF NEURORADIOLOGY. Technical Feasibility and Application of Mechanical Thrombectomy with the Solitaire FR Revascularization Device in Acute Basilar Artery Occlusion

P. Mordasini, C. Brekenfeld, J.V. Byrne, U. Fischer, M. Arnold, M.R. Heldner, R. Lüdi, H.P. Mattle, G. Schroth and J. Gralla

BACKGROUND AND PURPOSE: Acute BAO is a devastating neurological condition associated with a poor clinical outcome and a high mortality rate. Recanalization has been identified as a major prognostic factor for good outcome in BAO. Mechanical thrombectomy using retrievable stents is an emerging treatment option for acute stroke. First clinical trials using stent retrievers have shown promising high recanalization rates. However, these studies mainly included large artery occlusions in the anterior circulation with only a few or single cases of BAO. Therefore, the purpose of this study was to evaluate technical feasibility, safety, and efficacy of mechanical thrombectomy using retrievable stent in the treatment of acute BAO.

03 mayo 2012

AMERICAN JOURNAL OF NEURORADIOLOGY. Effectiveness of Mechanical Endovascular Thrombectomy in a Model System of Cerebrovascular Occlusion

J.Y. Chueh, A.K. Wakhloo and M.J. Gounis

BACKGROUND AND PURPOSE: A number of thrombectomy devices are currently undergoing clinical evaluation; meanwhile, various novel devices are under investigation. The aims of this study were to quantify flow restoration and the particle size distribution of the effluent pursuant to MET in an in vitro occlusion model.

29 octubre 2015

AMERICAN JOURNAL OF NEURORADIOLOGY. Endovascular Treatment of Unruptured Paraclinoid Aneurysms: Single-Center Experience with 400 Cases and Literature Review

K. Shimizu, H. Imamura, Y. Mineharu, H. Adachi, C. Sakai and N. Sakai

BACKGROUND AND PURPOSE: Paraclinoid aneurysms have been increasingly treated endovascularly. The natural history of these aneurysms has gradually been elucidated. The purpose of this study was to assess the safety and efficacy of endovascular treatment for these aneurysms.

18 febrero 2016

AMERICAN JOURNAL OF NEURORADIOLOGY. Training Guidelines for Endovascular Ischemic Stroke Intervention: An International Multi-Society Consensus Document

S.D. Lavine, K. Cockroft, B. Hoh, N. Bambakidis, A.A. Khalessi, H. Woo, H. Riina, A. Siddiqui, J.A. Hirsch, W. Chong, H. Rice, J. Wenderoth, P. Mitchell, A. Coulthard, T.J. Signh, C. Phatorous, M. Khangure, P. Klurfan, K. terBrugge, D. Iancu, T. Gunnarsson, O. Jansen, M. Muto, I. Szikora, L. Pierot, P. Brouwer, J. Gralla, S. Renowden, T. Andersson, J. Fiehler, F. Turjman, P. White, A.C. Januel, L. Spelle, Z. Kulcsar, R. Chapot, L. Spelle, A. Biondi, S. Dima, C. Taschner, M. Szajner, A. Krajina, N. Sakai, Y. Matsumaru, S. Yoshimura, M. Ezura, T. Fujinaka, K. Iihara, A. Ishii, T. Higashi, M. Hirohata, A. Hyodo, Y. Ito, M. Kawanishi, H. Kiyosue, E. Kobayashi, S. Kobayashi, N. Kuwayama, Y. Matsumoto, S. Miyachi, Y. Murayama, I. Nagata, I. Nakahara, S. Nemoto, Y. Niimi, H. Oishi, J. Satomi, T. Satow, K. Sugiu, M. Tanaka, T. Terada, H. Yamagami, O. Diaz, P. Lylyk, M.V. Jayaraman, A. Patsalides, C.D. Gandhi, S.K. Lee, T. Abruzzo, B. Albani, S.A. Ansari, A.S. Arthur, B.W. Baxter, K.R. Bulsara, M. Chen, J.E. Delgado Almandoz, J.F. Fraser, D.V. Heck,S.W. Hetts, M.S. Hussain, R.P. Kluczni, T.M. Leslie-Mawzi, W.J. Mack, R.A. McTaggart, P.M. Meyers, J. Mocco, C.J. Prestigiacomo, G.L. Pride, P.A. Rasmussen, R.M. Starke, P.J. Sunenshine, R.W. Tarr, D.F. Freij, M. Ribo, R.G. Nogueira, O.O. Zaidat, T. Jovin, I. Linfante, D. Yavagal, D. Liebeskind, R. Novakovic, S. Pongpech, G. Rodesch, M. Soderman, K. terBrugge, A. Taylor, T. Krings, D. Orbach, A. Biondi, L. Picard, D.C. Suh, M. Tanaka and H.Q. Zhang

BACKGROUND: Ischemic stroke is a leading cause of death and disability worldwide. Much of the long-term disability occurs in patients with Emergent Large Vessel Occlusion (ELVO). In fact, in these patients, occlusion of a major intracerebral artery results in a large area of brain injury often resulting in death or severe disability1. Until recently, intravenous tissue plasminogen activator (t-PA) was the only proven treatment for ELVO.

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