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ESTUDIOS


01 noviembre 2014

RADIOLOGY. Interventional Radiology: A Half Century of Innovation

Richard A. Baum, MD, MPA, MBA Stanley Baum, MD

The evolution of modern interventional radiology began over half century ago. Use of the same diagnostic imaging tools that had revolutionized the practice of medicine became a possibility in guiding real-time treatment of disease. This concept led to rapid treatment advances in every organ system of the body. It became clear that by utilizing imaging some patients could undergo targeted minimally invasive procedures, thus avoiding major surgery, while others could undergo procedures for previously unsolvable problems. The breadth of these changes now encompasses all of medicine and has forever changed the way we think about disease. In this brief review article, we will describe the major technologic advances in the field, as chronicled in the pages of Radiology. We will also explore the 50-year journey of interventional radiologists, from diagnostic imagers to practicing clinicians.

01 diciembre 2014

AMERICAN JOURNAL OF ROENTGENOLOGY. ALPHA Glycolytic Vasculogenesis Better Correlates With MRI and CT Imaging Techniques Than the Traditional Oxygen Vasculogenesis Theory

John R. Haaga, Rebecca Haaga, Indravadan Patel, Zachary Love and Joseph Moulter

OBJECTIVE. Traditional vasculogenesis has many contradictions related to treatment and imaging. This occurs because cancer also uses glycolysis, which does not need oxygen or arteries. Glycolytic lactate supports many procancer processes but high levels of it inhibit glycolysis.

01 diciembre 2014

AMERICAN JOURNAL OF ROENTGENOLOGY. Survival, Efficacy, and Safety of Small Versus Large Doxorubicin Drug-Eluting Beads TACE Chemoembolization in Patients With Unresectable HCC

Hasmukh J. Prajapati, Minzhi Xing, James R. Spivey, Steven I. Hanish, Bassel F. El-Raye, John S. Kauh, Zhengjia Chen and Hyun S. Kim

OBJECTIVE. The purpose of this study was to investigate the overall survival, efficacy, and safety of small (100–300 µm) versus large (300–500 and 500–700 µm) doxorubicin drug-eluting beads transarterial chemoembolization (DEB TACE) in patients with unresectable hepatocellular carcinoma (HCC).

01 diciembre 2014

AMERICAN JOURNAL OF ROENTGENOLOGY. Characterization of Liver Function Parameter Alterations After Transjugular Intrahepatic Portosystemic Shunt Creation and Association With Early Mortality

Leigh C. Casadaban, Ahmad Parvinian, Patrick M. Couture, Jeet Minocha, M. Grace Knuttinen, James T. Bui and Ron C. Gaba

OBJECTIVE. The purpose of this article is to characterize the temporal evolution and clinical impact of laboratory liver function parameters after transjugular intrahepatic portosystemic shunt (TIPS) creation.

01 diciembre 2014

AMERICAN JOURNAL OF ROENTGENOLOGY. Vascular Toxicity Associated With Chemotherapy and Molecular Targeted Therapy: What Should a Radiologist Know?

Saurabh Rohatgi, Jyothi P. Jagannathan, Michael H. Rosenthal, Kyung Won Kim, Nikhil H. Ramaiya and Katherine M. Krajewski

OBJECTIVE. Venous and arterial thromboembolic events and rarely hemorrhage are complications of chemotherapy and, more recently, of molecular targeted therapy in patients with solid and hematologic malignancies. This article will use a drug-based approach to illustrate, with examples, vessel damage and end-organ damage induced by molecular targeted therapy and chemotherapy in cancer patients and will provide a clinical perspective.

01 diciembre 2014

AMERICAN JOURNAL OF ROENTGENOLOGY. Neurofibromas With Imaging Characteristics Resembling Vascular Anomalies

Sabri Yilmaz, John A. Ozolek, Lauren L. Zammerilla, Charles R. Fitz, Lorelei J. Grunwaldt and John J. Crowley

OBJECTIVE. Although neurofibromas are rare, their initial clinical and imaging presentation can mimic those of vascular anomalies, particularly if the characteristic clinical features of neurofibromatosis are not present. The diagnostic challenges encountered in five cases of histologically proven neurofibromas, initially diagnosed as vascular anomalies, are reviewed and discussed.

01 diciembre 2015

JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY. Management of High Hepatopulmonary Shunting in Patients Undergoing Hepatic Radioembolization

Thomas J. Ward, MD, Anobel Tamrazi, MD, PhD, Marnix G.E.H. Lam, MD, PhD, John D. Louie, MD, Peter N. Kao, MD, PhD, Rajesh P. Shah, MD, Michael A. Kadoch, MD, Daniel Y. Sze, MD, PhD

Purpose: To review the safety of hepatic radioembolization (RE) in patients with high (≥ 10%) hepatopulmonary shunt fraction (HPSF) using various prophylactic techniques.

01 diciembre 2015

JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY. Role of Locoregional Therapy and Predictors for Dropout in Patients with Hepatocellular Carcinoma Listed for Liver Transplantation

Rahul A. Sheth, MD, Madhukar S. Patel, MD, Brian Koottappillil, BA, Jigesh A. Shah, DO, Rahmi Oklu, MD, PhD, Peter Mueller, MD, Parsia A. Vagefi, MD, Suvranu Ganguli, MD

Purpose: To identify factors associated with removal from the liver transplantation waitlist because of death, deterioration of condition, or exceeding Milan criteria in patients with hepatocellular carcinoma (HCC), with emphasis on the role of locoregional therapy (LRT), defined as percutaneous thermal ablation and drug-eluting embolic chemoembolization, as bridge therapy.

01 diciembre 2015

WORLD JOURNAL OF HEPATOLOGY. Management of biliary complications after liver transplantation

Riccardo Memeo, Tullio Piardi, Federico Sangiuolo, Daniele Sommacale, Patrick Pessaux

Biliary complications (BC) currently represent a major source of morbidity after liver transplantation. Although refinements in surgical technique and medical therapy have had a positive influence on the reduction of postoperative morbidity, BC affect 5% to 25% of transplanted patients. Bile leak and anastomotic strictures represent the most common complications. Nowadays, a multidisciplinary approach is required to manage such complications in order to prevent liver failure and retransplantation.

28 noviembre 2015

WORLD JOURNAL OF RADIOLOGY. Iliac vein compression syndrome: Clinical, imaging and pathologic findings

Katelyn N Brinegar, Rahul A Sheth, Ali Khademhosseini, Jemianne Bautista, Rahmi Oklu

May-Thurner syndrome (MTS) is the pathologic compression of the left common iliac vein by the right common iliac artery, resulting in left lower extremity pain, swelling, and deep venous thrombosis. Though this syndrome was first described in 1851, there are currently no standardized criteria to establish the diagnosis of MTS. Since MTS is treated by a wide array of specialties, including interventional radiology, vascular surgery, cardiology, and vascular medicine, the need for an established diagnostic criterion is imperative in order to reduce misdiagnosis and inappropriate treatment. Although MTS has historically been diagnosed by the presence of pathologic features, the use of dynamic imaging techniques has led to a more radiologic based diagnosis. Thus, imaging plays an integral part in screening patients for MTS, and the utility of a wide array of imaging modalities has been evaluated. Here, we summarize the historical aspects of the clinical features of this syndrome. We then provide a comprehensive assessment of the literature on the efficacy of imaging tools available to diagnose MTS. Lastly, we provide clinical pearls and recommendations to aid physicians in diagnosing the syndrome through the use of provocative measures.

28 noviembre 2015

WORLD JOURNAL OF GASTROENTEROLOGY. Management of early hepatic artery occlusion after liver transplantation with failed rescue

Chih-Yang Hsiao, Cheng-Maw Ho, Yao-Ming Wu, Ming-Chih Ho, Rey-Heng Hu, Po-Huang Lee

Hepatic artery thrombosis is a serious complication after liver transplantation which often results in biliary complications, early graft loss, and patient death. It is generally thought that early hepatic artery thrombosis without urgent re-vascularization or re-transplantation almost always leads to mortality, especially if the hepatic artery thrombosis occurs within a few days after transplantation. This series presents 3 cases of early hepatic artery thrombosis after living donor liver transplantation, in which surgical or endovascular attempts at arterial re-vascularization failed. Unexpectedly, these 3 patients survived with acceptable graft function after 32 mo, 11 mo, and 4 mo follow-up, respectively. The literatures on factors affecting this devastating complication were reviewed from an anatomical perspective. The collective evidence from survivors indicated that modified nonsurgical management after liver transplantation with failed revascularization may be sufficient to prevent mortality from early hepatic artery occlusion. Re-transplantation may be reserved for selected patients with unrecovered graft function.

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